• Title/Summary/Keyword: Radiation hazards

Search Result 90, Processing Time 0.027 seconds

Lack of any Impact of Histopathology Type on Prognosis in Patients with Early-Stage Adenocarcinoma and Squamous Cell Carcinoma of the Uterine Cervix

  • Teke, Fatma;Yoney, Adnan;Teke, Memik;Inal, Ali;Urakci, Zuhat;Eren, Bekir;Zincircioglu, Seyit Burhanedtin;Buyukpolat, Muhammed Yakup;Ozer, Ali;Isikdogan, Abdurrahman;Unsal, Mustafa
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.15 no.6
    • /
    • pp.2815-2819
    • /
    • 2014
  • Background: The aim of this study was to evaluate the prognosis of patients with stage IA-IIB cervical carcinoma and to investigate a possible correlation of histology with prognosis. Materials and Methods: Two hundred fifty one patients with adenocarcinoma and squamous cell carcinoma (SCC) histology for FIGO (International Federation of Gynecology and Obstetrics) stage IA-IIB uterine cervical carcinomas at the Radiation Oncology Clinic of GH Okmeydan Training and Research Hospital between January 1996 and December 2006 were selected, analyzed retrospectively and evaluated in terms of general characteristics and survival. Disease-free survival (DFS) and overall survival (OS) was calculated using the Kaplan-Meier method and differences were compared with the log-rank test. Multivariate analysis using a Cox-proportional hazards model was used to adjust for prognostic factors and to estimate hazard ratio (HR) with 95% confidence interval (CI). Results: There was no differences between the two tumour types in age, stage, pelvic nodal metastasis, parametrial invasion, surgical margin status, DSI, LVSI, maximal tumor diameter, grade, and treatment modalities. 5-year OS and DFS were 73% and 77%, versus 64% and 69%, for SCC and adenocarcinoma, respectively (p> 0.05). Multivariate analysis revealed independent prognostic factors including pelvic nodal metastasis and resection margin status for OS (p=0.008, p=0.002, respectively). Conclusions: Prognosis of FIGO stage IA-IIB cervical cancer patients was found to be the same for those with adenocarcinoma and SCC.

Prognostic value of FDG PET/CT during radiotherapy in head and neck cancer patients

  • Kim, Suzy;Oh, Sowon;Kim, Jin Soo;Kim, Yu Kyeong;Kim, Kwang Hyun;Oh, Do Hoon;Lee, Dong-Han;Jeong, Woo-Jin;Jung, Young Ho
    • Radiation Oncology Journal
    • /
    • v.36 no.2
    • /
    • pp.95-102
    • /
    • 2018
  • Purpose: To evaluate the prognostic value of $^{18}F$-fluorodeoxyglucose positron-emission tomography (FDG PET) with computed tomography (CT) before and during radiotherapy (RT) in patients with head and neck cancer. Methods: Twenty patients with primary head and neck squamous cell carcinoma were enrolled in this study, of whom 6 had oropharyngeal cancer, 10 had hypopharyngeal cancer, and 4 had laryngeal cancer. Fifteen patients received concurrent cisplatin and 2 received concurrent cetuximab chemotherapy. FDG PET/CT was performed before RT and in the 4th week of RT. The parameters of maximum standardized uptake value, metabolic tumor volume, and total lesion glycolysis (TLG) of the primary tumor were measured, and the prognostic significance of each was analyzed with the Cox proportional hazards model. Results: Higher TLG (>19.0) on FDG PET/CT during RT was a poor prognostic factor for overall survival (OS) (p = 0.001) and progression-free survival (PFS) (p = 0.007). In the multivariate analysis, TLG during RT as a continuous variable was significantly associated with OS and PFS rate (p = 0.023 and p = 0.016, respectively). Tumor response worse than partial remission at 1 month after RT was another independent prognostic factor for PFS (p = 0.024). Conclusions: Higher TLG of the primary tumor on FDG PET/CT during RT was a poor prognostic factor for OS and PFS in patients with head and neck cancer.

Assessment of occupational radiation exposure of NORM scales residues from oil and gas production

  • EL Hadji Mamadou Fall;Abderrazak Nechaf;Modou Niang;Nadia Rabia;Fatou Ndoye;Ndeye Arame Boye Faye
    • Nuclear Engineering and Technology
    • /
    • v.55 no.5
    • /
    • pp.1757-1762
    • /
    • 2023
  • Radiological hazards from external exposure of naturally occurring radioactive materials (NORM) scales residues, generated during the extraction process of oil and gas production in southern Algeria, are evaluated. The activity concentrations of 226Ra, 232Th, and 40K were measured using high-purity gamma-ray spectrometry (GeHP). Mean activity concentration of 226Ra, 232Th and 40K, found in scale samples are 4082 ± 41, 1060 ± 38 and 568 ± 36 Bq kg-1, respectively. Radiological hazard parameters, such as radium equivalent (Raeq), external and internal hazard indices (Hex, Hin), and gamma index (Iγ) are also evaluated. All hazard parameter values were greater than the permissible and recommended limits and the average annual effective dose value exceeded the dose constraint (0.3 mSv y-1). However, for occasionally exposed workers, the dose rate of 0.65 ± 0.02 mSv y-1 is lower than recommended limit of 1 mSv y-1 for public.

Assessment of radioactivity levels and radiation hazards in building materials in Egypt

  • Ahmed E. Abdel Gawad;Mohamed Y. Hanfi;Mostafa N. Tawfik;Mohammed S. Alqahtani;Hamed I. Mira
    • Nuclear Engineering and Technology
    • /
    • v.56 no.2
    • /
    • pp.707-714
    • /
    • 2024
  • Different degrees of natural radioactivity found in quartz can have negative consequences on health. Quartz vein along the investigated Abu Ramad area, Egypt, had its natural radioactivity assessed. The HPGe spectrometer was used to determine the role played by the radionuclides 238U, 232Th, and 40K in the gamma radiation that was emitted, and the results showed that these concentrations are 484.64 ± 288.4, 36.8 ± 13.1 and 772.2 ± 134.6 Bq kg-1 were higher than the corresponding reported global limits of 33, 45, and 412 Bq kg-1 for each radionuclide (238U, 232Th, and 40K). Among the radiological hazard parameters, the excess lifetime cancer risk (ELCR) is estimated and it's mean value of ELCR (1.2) is higher than the permissible limit of 0.00029. The relationship between the radionuclides and the associated radiological hazard characteristics was investigated based on multivariate statistical methods including Pearson correlation, principal component analysis (PCA), and hierarchical cluster analysis (HCA). According to statistical research, the radioactive risk of quartz is primarily caused by the 238U, 232Thand 40K. Finally, applying quartz to building materials would pose a significant risk to the public.

Increase in the Th1-Cell-Based Immune Response in Healthy Workers Exposed to Low-Dose Radiation - Immune System Status of Radiology Staff

  • Karimi, Gholamreza;Balali-Mood, Mahdi;Alamdaran, Seyed-Ali;Badie-Bostan, Hassan;Mohammadi, Elaheh;Ghorani-Azam, Adel;Sadeghi, Mahmood;Riahi-Zanjani, Bamdad
    • Journal of Pharmacopuncture
    • /
    • v.20 no.2
    • /
    • pp.107-111
    • /
    • 2017
  • Objectives: Radiation is one of the most important sources of free radical (such as reactive oxygen species) production, which plays an essential role in the etiology of over hundred diseases. The aim of the study was to investigate some immune parameters and hematological indices in healthy workers of the Radiology Department, University Hospital of Mashhad, Iran. Methods: The study was performed on 50 healthy workers: 30 radiology staff as the case group and 20 laboratory workers as the control group. The radiation dose received by the radiology staff participating in the study was less than the annual maximum permissible level, 50 millisievert. Hematological parameters, lymphocyte proliferation and cytokine production were studied in both groups. Results: Among healthy radiology workers, the hematological indices did not differ statistically; however, their proliferation indices and $IFN-{\gamma}$ levels showed significant increases in parallel with decreases in the IL-4 levels as compared to controls. The immune system of workers exposed to low-dose ionizing radiation was found to be shifted from a Type 2 to a Type 1 response to promote cellular immunity. Conclusion: Based on our data, exposure to low-dose ionizing radiation may decrease the prevalence, frequency, and recurrence of various cancers and infectious diseases because of an increase in Th1-cell-based response, thus leading to more protection of the human body against tumor cells and foreign agents and possibly increased longevity. However, due to high rate of fluoroscopy use for interventional radiology, we suggest continuing research projects on radiation protection and hazards to prevent irreversible damage. As a recommendation, in future studies, radiology staff with a weakened immunity due to high radiation exposure should be considered as good choices to be treated using acupuncture techniques because acupuncture has been demonstrated to enhance the function and the number of immune cells.

Test and Analysis of Electromagnetic Compatibility in Next-Generation Train (차세대전동차 유도장애시험 및 분석)

  • Lee, Chang-Mu;Lee, Han-Min;Kim, Ju-Rak;Kim, Kil-Dong
    • Proceedings of the KSR Conference
    • /
    • 2011.10a
    • /
    • pp.2031-2036
    • /
    • 2011
  • To leading subway technology Advanced Urban Transit System is developed by national research and development. Next-generation trains equipped with direct driving permanent magnet traction motor and individually controlled propulsion system. Electromagnetic properties of the Next-Generation Train from four perspectives will be discussed. The first is closely related to human hazards that affect the 60Hz low frequency electromagnetic field. The Second is inductive noise that affect railroad signal system. The third is conductive noise that affect communication line near railroad. The 4th is radiation noise that may affect electronic equipment near the railroad tracks.

  • PDF

Characteristics of Induced Voltage in Loop Structures from High-frequency Radiation Antenna (고주파 방사에 의한 루프형 구조물에서의 유도전압 특성)

  • Choi, Sang-Won;Kwon, Hyuk-Myun
    • Journal of the Korean Society of Safety
    • /
    • v.27 no.5
    • /
    • pp.49-54
    • /
    • 2012
  • There is a possibility that electrical sparks may occur at discontinuities in metallic structures from distance of close to high power radio/radar transmitters. Voltage may be induced on these metallic structures by the radio-frequency transmitter. In this case, a person who comes into contact with these structure may be undergone a severe electrical shock. In this paper, assessment of the electrical shock and ignition hazards was investigated through experimental which are consisted radio transmitter and metallic loop-type structure in shield room. We measured that the induced voltage was highest at 61 MHz of transmission frequency, and confirmed the possibility of electric shock and explosion induced by a voltage or spark. But it is needed additional research where is opened site.

Meteorological Data Integrity for Environmental Impact Assessment in Yongdam Catchment (용담댐시험유역 환경영향평가의 신뢰수준 향상을 위한 기상자료의 품질검정)

  • Lee, Khil-Ha
    • Journal of Environmental Science International
    • /
    • v.29 no.10
    • /
    • pp.981-988
    • /
    • 2020
  • This study presents meteorological data integrity to improve environmental quality assessment in Yongdam catchment. The study examines both extreme ranges of meteorological data measurements and data reliability which include maximum and minimum temperature, relative humidity, dew point temperature, radiation, heat flux. There were some outliers and missing data from the measurements. In addition, the latent heat flux and sensible heat flux data were not reasonable and evapotranspiration data did not match at some points. The accuracy and consistency of data stored in a database for the study were secured from the data integrity. Users need to take caution when using meteorological data from the Yongdam catchment in the preparation of water resources planning, environmental impact assessment, and natural hazards analysis.

The Research of the HERO Test and Evaluation Technique (HERO 시험평가 기법 연구)

  • Shin, Seung-Je
    • Journal of the Korea Institute of Military Science and Technology
    • /
    • v.10 no.2
    • /
    • pp.76-83
    • /
    • 2007
  • This report presents the test technique using optic thermal sensor for the HERO evaluation of equipment installed EED. The calibration method of EED-thermal sensor assembly is explained by relation between the current in bridge wire and voltage in thermal sensor. And the HERO test and evaluation method is indicated based on MIL-STD-464A and MIL-STD-331C. The safety and reliability levels of EED-thermal sensor assembly are evaluated when exposed in the electromagnetic environment.

Effects of Microgravity on Human Physiology

  • Nguyen, Nguyen;Kim, Gyutae;Kim, Kyu-Sung
    • Korean journal of aerospace and environmental medicine
    • /
    • v.30 no.1
    • /
    • pp.25-29
    • /
    • 2020
  • Space exploration is one of the dreams of humankind. However, the intriguing environment was a challenge for the human body, where we must counter with many extreme conditions such as thermal support, radiation, microgravity. Life, as well as the human body, developed and evolved in the continuous presence of gravity, especially when living creatures transfer from the ocean to the land. Once this gravitational force doesn't impact on the body, the drastic changes occur. Some of these changes were observed immediately, while others progress only slowly. Since the first orbital flight was performed, several hazards for the organs of the human body were identified [1]. These changes in human physiology can reverse when astronauts return to Earth. This article will review the published findings of the effects of microgravity exposure on the human body.