• Asian Pacific Journal of Cancer Prevention
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• 제15권15호
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• pp.6161-6164
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• 2014

Background: We have reported the radiation could activate STAT3, which subsequently promotes the invasion of A549 cells. We here explored the dose- and time-response of STAT3 to radiation and the effect of radiation on upstream signaling molecules. Materials and Methods: A549 cells were irradiated with different doses of ${\gamma}$-rays. The expression of and nucleus translocation of p-STAT3 in A549 cells were detected by immunoblotting and immunofluorescence, respectively. The level of phosphorylated EGFR was also assessed by immunoblotting, and IL-6 expression was detected by real time PCR and ELISA. Results: Radiation promoted the phosphorylation of STAT3 at Y705 in a dose- and time-dependent manner and nuclear translocation. The level of phosphorylated EGFR in A549 cells increased after radiation. In additional, the mRNA and protein levels of IL-6 in A549 cells were also up regulated by radiation. Conclusions: STAT3 is activated by radiation in a dose-and time-dependent manner, probably due to radiation-induced activation of EGFR or secretion of IL-6 in A549 cells.

• Journal of Radiation Protection and Research
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• 제5권1호
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• pp.48-51
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• 1980

• Journal of Radiation Protection and Research
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• 제5권1호
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• pp.26-31
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• 1980

• Journal of Radiation Protection and Research
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• 제10권1호
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• pp.74-85
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• 1985

ICRU 보고서 39에서 새로이 정의된 의부방사선피폭에 의한 선량당량평가 목적의 네 가지 실용량에 대하여 그 도입의 배경과 기존량과의 관계, 그리고 방사선 방어 및 측정에서의 전망에 대하여 기술하였다.

• Imaging Science in Dentistry
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• 제37권3호
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• pp.117-126
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• 2007

Although the diagnostic information provided by radiographs may be of definite benefit to the patients, the radiographic examination does carry the potential for harm from exposure to ionizing radiation. Therefore we should try to expose radiation as low as reasonably achievable and to give diagnostic information to patients as much as possible. All of dentists should have competence in radiation protection. I wish to deal with what we should do for the optimization of radiation protection in dental clinic.

• Journal of Radiation Protection and Research
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• 제48권2호
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• pp.68-76
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• 2023

Background: In the process of discussion on the possibility of using radionuclide-contaminated soil and debris generated by radiation disasters, a strategy for the proper management of radiation exposure protection while considering the source of the contaminated materials is necessary. Materials and Methods: The radiological protection criteria that are likely to be applied to the source-related approach based on the International Commission on Radiological Protection recommendations and the International Atomic Energy Agency safety standards are summarized. We proposed five interpretations of radiation protection to contribute to the promotion of discussion on the possibility of using a part of low-level-radionuclide-contaminated soil and debris in the post-accident rehabilitation. Interpretations I to III are based on the idea of "using a reference level to protect the public in post-accident rehabilitation," whereas IV and V are based on the idea of "using the dose constraint to protect the public in the post-accident rehabilitation when the sources are handled in a planned activity." The former idea is subdivided into three based on the definition of the source, which is managed by the reference level, and the latter idea is divided into two depending on whether or not additional dose from using contaminated materials is deemed acceptable. Results and Discussion: To confirm the applicability of the five interpretations presented, we suggested the concrete values of protection criteria via two feasible cases. In this case study, we proposed radiation protection by the dose constraint based on the Interpretation IV and chose 1 mSv/yr for the public and 20 mSv/yr for workers dealing with radionuclide-contaminated materials. Conclusion: We concretely and systematically demonstrated how the concept of radiation protection can be applied to the process of discussion on the possibility of using radionuclide-contaminated materials within the framework of an international system of protection. This study's findings can provide necessary information to discuss the possibility of using radionuclide-contaminated materials as an alternative option for recovery and reconstruction after a radiation disaster from the viewpoint of radiation protection.

• Journal of Radiation Protection and Research
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• 제28권1호
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• pp.65-73
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• 2003

The paper discusses results of recent international intercomparison exercises on internal dose assessments, status of up to date internal dosimetry methods and the radiological legislation developed and implemented in Korea, European Union and Ukraine. The system of radiation protection in Korea is based on the Korean Atomic Energy Regulatory Enforcement on Safety Standards (Ministry Notice No. 2001-2). The notice is based on the recommendations in ICRP Publication 60 (1990) and IAEA Basic Safety Standards (1996). But the full implementation of the notice by the end of the year 2002 is not required because of the socio-economic situation and inexperience in internal radiation dosimetry Regulatory framework for internal radiation dosimetry is under development toward the full implementation of the notice from January 1, 2003. The system of radiation protection in Ukraine is based on the National radiation protection regulatory code NRBU-97. The code was developed and adopted in 1998 and replaced the Regulations of Former Soviet Union. The document is based on the ICRP Publication 60, Euratom Directive 96/29 and IAEA Basic Safety Standards (1996). The transitional period of 5 years (effected till January 2003) is established for implementation of all requirements of this new regulation. The system of radiation protection in the European Community is based on the Council Directive 96/29/Euratom, adopted in 1996 and enforced from 13 May 2000. Directive 96/29/Euratom has the status of the European law.

• Journal of Radiation Protection and Research
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• 제39권2호
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• pp.103-108
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• 2014

Following the emergency work in Fukushima Daiichi nuclear power plant, more attention was paid for the radiation protection of workers working under severe accident condition. The protection procedure for the emergency workers, including the on-site emergency center, the seismic isolated building and the reestablishment of the radiation protection framework were analyzed to investigate drawbacks and deficiencies which led to adverse effects on the emergency planning and on emergency workers' health and comfort. Those drawbacks were identified and studied, and then suggestions were made to enhance the emergency working condition to avoid any future problems during severe accident emergency work and management.

• 한국콘텐츠학회논문지
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• 제16권10호
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• pp.563-572
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• 2016

본 연구는 간호학생과 간호사를 대상으로 방사선 방어에 대한 지식, 태도와 교육 요구를 조사하여 방사선 방어에 대한 중요성을 인지하도록 하고, 나아가 방사선 방어를 위한 안전관리의 효과적인 교육 프로그램 개발에 기초자료를 제공하고자 하였다. B광역시에 소재한 일 대학의 3, 4학년 간호학생(n=139)과 간호사(n=135) 총 274명을 대상으로 45문항의 설문지로 방사선 방어에 대한 지식, 태도, 교육 요구를 조사하였다. 그 결과 방사선 방어를 위한 안전관리 교육이 미흡한 실정이고, 이에 비해 교육요구와 참여의사는 매우 높으며, 방사선 방어에 대한 지식이 높을수록 방사선 방어에 대한 태도 또한 높아진다는 것을 알 수 있었다. 따라서 대상자의 교육 요구를 반영한 교육과정 개발이 매우 필요하며, 간호사의 외부교육 또는 병원 자체교육에서도 방사선 방어에 대한 프로그램의 운영이 필요하다고 볼 수 있다. 또한 교육 효과를 높이기 위하여 전문가를 통한 강연과 시청각 자료를 활용한 교육이 요구된다.

• 전기학회논문지
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• 제62권10호
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• pp.1421-1424
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• 2013

The electronic equipment which is exposed to high level pulsed radiation is damaged by Upset, Latchup, and Burnout. Those damages come from the instantaneous photocurrent from electron-hole pairs generated in itself. Such damages appear as losses of a power in military weapon system or as a blackout in aerospace equipment and eventually caused in gross loss of national power. In this paper, we have implemented a RDC(Radiation detection and control module) as a part of the radiation protection technology of the electronic equipment or devices from the pulsed gamma radiation. The RDC, which is composed of pulsed gamma-ray detection sensor, signal processors, and pulse generator, is designed to protect the an important electronic circuits from the a pulse radiation. To verify the functionality of the RDC, LM118s, which had damaged by the pulse radiation, were tested. The test results showed that the test sample applied with the RDC was worked well in spite of the irradiation of a pulse radiation. Through the experiments we could confirm that the radiation protection technology implemented with the RDC had the functionality of radiation protection for the electronic devices.