• 대한방사선기술학회지:방사선기술과학
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• 제1권1호
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• pp.15-24
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• 1978

The characteristics of the rare earth phosphors intensifying screen (LM-6, Grenex-8) as compared with $CaWO_4$ intensifying screen had been studied utilizing several common x-ray films, and found the following results. 1. Compared with the conventional CaWO4 intensifying screen, the rare earth phosphors intensifying screen was found to be more sensitive over to 1.26-3.47 times. So the radiation exposure could be reduced to 1/1.26 -1/3.47. 2. Sharpness as well as the film speed were both increased. So the motion blurring and geometrical unsharpness could be decreased. 3. In spite of that the film speed was increased, photographic contrast was kept up. Therefore, the more ideal film of greater latitude could be obtained. 4. The effects of the rare earth phosphors intensifying screen would be much increased as using with orthochromatic x-ray films.

• The Journal of the Acoustical Society of Korea
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• 제16권1E호
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• pp.9-14
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• 1997

Check valves used in industrial and Nuclear Power Plant safety systems are susceptible to failure modes generally associated with wear of internal parts. Specifically, hinge pins, disc studs, pistons, and other mechanical parts may degrade over time, and in some cases, may which might produce a disabling event leading to plant or process shutdown. The primary diagnostic technique in the past has been to disassemble the valves. This procedure is costly, time consuming, and in the nuclear industry, it can lead to radiation exposure in some situations. Additionally repair and reassembly of a valve does not ensure proper operation. Non-intrusive diagnostic technologies including acoustics and magnetics with a digital signal analysis allow to evaluate check valve performance without a disassembly and is able to help the user detect degraded valve conditions.

• 대한방사선기술학회지:방사선기술과학
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• 제20권2호
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• pp.49-55
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• 1997

This study was carried out to investigate radiographical and operating conditions of X-ray units and exposure doses to patients during chest radiography, so that the results could provide basic data used for reducing the exposure dose and for providing the diagnostic information with better quality. The conditions and exposure doses of 100 X-ray units mainly used for chest radiography were examined and also 100 radiological technologists mainly handling those apparatus at 76 medical facilities in Pusan were surveyed using a questionnaire from October 1 to December 31 in 1995. The following results were obtained from the study : 1. It was found that most units were capable of taking a high tube voltage radiography by showing 67% of the units equipped with the maximum tube voltage of 150 kV, 94% with more than 500 mA for the rating capacity and 85% with the full wave type of a signal phase. 2. For actual chest radiographical conditions, however, 80% of the units were operated at $60{\sim}100\;kVp$ and only 14% at 100 kVp and over for the high tube voltage. 3. The average exposure time was less than 0.1 second, and eighty four percent of the units adapted the X-ray tube currents ranging from 200 to 300 mA, 80% the focus-film distances between 180 and 210 cm, and 63% the focus sizes of more than 2.0 mm. 4. Most units(98%) employed additional filters made of aluminum, 75% the thickness of filters less than 2.0 mm, and only 2 units the compound filters. 5. Ortho chromatic system was only adopted in 13% of screen film system for the units, and 73% used the grid ratio at 8 : 1 for the low tube voltage during chest radiography. 6. The average exposure dose of all X-ray units during chest radiography was $371\;{\mu}Sv$ with a difference of about 16 times between the minimum to the maximum, and $386\;{\mu}Sv$ both at hospitals and at health centers, followed by $380\;{\mu}Sv$ at general hospitals and $263\;{\mu}Sv$ at university hospitals without showing any statistically significant differences. In conclusion, since patients during chest radiography at medical facilities in Pusan exposed to high levels of radiation, it is recommended that appropriate added filters and grids necessary for the high tube voltage radiography and high-speed screen systems should be adopted and used as soon as possible in order to reduce exposure dose to the patients.

• Radiation Oncology Journal
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• 제28권1호
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• pp.39-49
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• 2010

목 적: 좌측 유방의 방사선치료에 있어, 3 빔 또는 5 빔을 이용한 세기변조방사선치료(intensity modulated radiation therapy, IMRT)와 다중빔조사영역 치료기법(multistatic fields techniques, MSF) 사이의 선량학적 차이를 분석하고자 하였다. 대상 및 방법: 개선된 선량 균일성을 만들 수 있는 가능성을 지닌 두 종류의 방사선치료 기술을 서로 비교 분석하였다. 첫째, 다중빔조사영역치료로 주조사야와 소조사야를 동시에 사용하여 치료하였다. 둘째, 고정된 다엽 조준기를 사용하는 IMRT로, 3 빔 또는 5 빔을 이용하였다. 유방보존술 후 방사선치료를 받은 16명의 초기 좌측 유방암 환자들을 대상으로 방사선치료계획들을 세운 다음, 이들을 선량학적 측면에서 비교 분석하였다. 결 과: $V_{95}$와 선량균일지수의 평균값은, 이 세 치료 사이에 통계학적으로 유의한 차이가 없었다. 방사선처방선량의 110% 이상을 받는 극심한 열점은 세 치료 모두에서 관찰되지 않았다. 동측 폐와 심장의 피폭 선량측정인자들에 대한 Tukey 검정에서, 세기변조방사선치료가 다중빔조사영역치료에 비해 저선량 영역의 피폭 선량을 유의하게 증가시킨 반면, 오히려 고선량 영역에서는 다중빔조사영역치료가 방사선 피폭을 약간 증가시켰다. 결 론: 선량 균일성 개선을 위해, 통상적인 쐐기기법 대신, 세기변조방사선치료보다 쉽게 계획되고 실시 될 수 있는 다중빔조사영역치료의 적용은 초기 좌측 유방암의 방사선치료 기술로 적합하다고 생각한다.

• Nuclear Engineering and Technology
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• 제17권3호
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• pp.216-223
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• 1985

원자력 발전소로부터 방출되는 기체상 방사성 물질에 의한 환경 영향을 평가함에 있어서 방사성 물질의 대기중에서의 수송과 확산을 기술하는 모델로써 Gaussian plume mode띠 널리 사용되고 있다. Gaussian plume model은 평탄한 지형에 적용하도록 만들어진 모델이므로 대부분의 국토가 복잡한 산악으로 구성된 한극의 경우에 적용하기 위해서는 모델의 수정이 필요하다. 본 논문에서는 2차원적 x-ｚ 평면에서 확산방정식을 해석한 numerical diffusion model과 Gaussian plume model을 비교하여, Gaussian plume mode에서 가장 중요한 변수인 dispersion coefficient를 지형의 높이에 대하여 보정하였다. 보정된 dispersion coefficient 값을 Gaussian plume mode에 적용시켜 계산을 수행한 결과를 보면, 산악지역에서의 방사성 물질의 농도는 평지에서보다 낮게 나타나고 있다.

• Journal of Multimedia Information System
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• 제7권2호
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• pp.147-156
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• 2020

The author Nakajima was involved in the field of disaster communications and emergency medical care as guest research scientist at the Fukushima Nuclear Accident Independent Investigation Commission established by the National Diet of Japan and reviewer of the Commission's report, and Kurokawa was the chairman of this Commission. Looking back over a decade, we are on the liability issue of bureaucrats and telecom operators, so it's becoming clear what was hidden at the time. The battery of NTT DoCoMo's mobile phone repeaters had a capacity of only about 24 hours, and communication failures increased after one day. The Government also failed to issue an announcement of "Vent from reactor" under the Telecommunications Act Article No. 129. This mistake lost the opportunity to use the third-party telecommunications (e.g. taxi radios). Furthermore, as a result of LASCOM (telecommunications satellite network for local governments via GEO) and a variety of unexpected communication failures, the evacuation order "Escape!" could not be notified to the general public well. As a result, the general public was exposed to unnecessary radiation exposure. Such bureaucratic slow action in emergencies is common in the response to the 2020 coronavirus.

• 한국재료학회지
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• 제18권8호
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• pp.427-431
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• 2008

The mechanical property of a phosphore layer was investigated by measuring the resolution (LP/mm) and by positron annihilation spectroscopy and SEM. Image plate samples containing the phosphore layer were irradiated by X-rays in a hospital numerous times over a course of several years. The LP/mm values of a (Ba,Sr)FBr : Eu image plate irradiated by X-rays varied between 2.2 and 2.0 over a period of four years. Coincidence Doppler Broadening (CDB) positron annihilation spectroscopy was used to analyze defect structures. The S parameters of the samples from hospital use varied from 0.6219 to 0.6232. There was a positive relationship between the time of exposure to the X-rays and the S parameters. Most of the defects were found to have been generated by X-rays.

• 전자공학회논문지
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• 제50권2호
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• pp.203-209
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• 2013

Digital Radiography(DR)는 film/screen(F/S)과 비교하여 넓은 계조와 높은 Detective Quantum Efficiency(DQE), Modulation Transfer function(MTF)를 바탕으로 화질의 개선과 저 선량으로 검사가 가능할 것으로 예상됐지만 기대와는 다르게 과노출이 Signal to Noise Ratio(SNR)향상을 가져 오면서 환자 피폭선량의 증가를 가져오게 되었으며 이는 Dose Creep이라는 개념으로 설명 된다. DR에서의 선량 증가 이유는 F/S의 촬영에서 사용했던 관전압(kVp)을 고정 적용하여 Auto Exposure Control(AEC)를 사용하기 때문에 과노출을 유발 할 수 있다. 이에 본 논문은 DR에서 적합한 일반촬영 방법을 제안하고자 관전압이 대조도에 주는 영향, 관전류(mA)변화에 따른 MTF 측정, 머리 모형을 촬영한 영상의 Peak Signal to Noise Ratio(PSNR) 측정을 통해 정량적 평가를 시행 하였다. 그 결과 관전압에 의한 대조도 변화는 후보정 이후 개선이 가능하며, 관전류에 의한 MTF 측정 결과 50%영역은 1.41~1.39 lp/mm, 10% 영역은 3.19~2.8 lp/mm로 관전류 변화에 따른 초점크기 변화는 영상의 해상력에 영향을 주지 않는다. 영상의 PSNR측정 결과는 관전압과 관전류가 증가 하여도 90kVp를 제외하고 30dB 이상으로 시각에 의한 영상의 차이를 인지하기 어렵다. 실험결과를 바탕으로 디지털 일반촬영에서 관전압은 80kVp 이상 100kVp이하, 관전류는 선예도와 상관 관계가 없으므로 선량과 조사시간을 단축 시킬 수 있는 방향으로 사용하기를 제안한다.

• Animal cells and systems
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• 제5권4호
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• pp.267-274
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• 2001

Calpains are a family of cysteine proteases existing primarily in two forms designated by the $Ca^{2+}$ concentration needed for activation in vitro, $\mu$-calpain (calpain-I) and m-calpain (calpain-II). The physiologica1 roles of calpains remain unclear. Many groups have proposed a role for calpains In apoptosis, but their patterns of activation are not well characterized. Calpains have been implicated in neutrophil apoptosis, glucocorticoid-induced thymocyte apoptosis, as well as many other apoptotic pathways. Calpain activation in apoptosis is usually linked upstream or downstream to caspase activation, or in a parallel pathway alongside caspase activation. Calpains have been suggested to be involved in DNA fragmentation (via endonuclease activation), but also as effector proteases that cleave cellular proteins involved in DNA repair, membrane associated proteins and other homeostatic regulatory proteins. Recently, our laboratory demonstrated $\mu$-calpain activation in NAD(P)H: quinone oxidoreducatse 1 (NQO1)-expressing cells after exposure to $\beta$-lapachone, a novel quinone and potential chemo- and radio-therapeutic agent. Increased cytosolic $Ca^{2+}$ in NQO1-expressing cells after $\beta$-lapachone exposures were shown to lead to $\mu$-calpain activation. In turn, $\mu$-calpain activation was important for substrate proteolysis and DNA fragmentation associated with apoptosis. Upon activation, $\mu$-calpain translocated to the nucleus where it could proteolytically cleave PARP and p53. We provided evidence that $\beta$-lapachone-induced, $\mu$-calpain stimulated, apoptosis did not involve any of the known caspases; known apoptotic caspases were not activated after $\beta$-lapachone treatment of NQO1-expressing cells, nor did caspase inhibitors have any effect on $\beta$-1apachone-induced cell death. Elucidation of processes by which $\beta$-1apachone-stimulated $\mu$-calpain activation and calpains ability to activate endonucleases and induce apoptosis independent of caspase activity will be needed to further develop/modulate $\beta$-lapachone for treatment of human cancers that over-express NQO1.

• Imaging Science in Dentistry
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• 제48권2호
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• pp.103-109
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• 2018

Purpose: To analyze cone-beam computed tomography (CBCT) use, indications, and exposure parameters in San $Jos{\acute{e}}$, Costa Rica. Materials and Methods: A cross-sectional study was performed. All CBCT examinations over a period of 6 months at 2 radiological centers in San $Jos{\acute{e}}$, Costa Rica were evaluated. The examinations were performed with Veraview EPOC X550 and Veraviewepocs 3D R100 equipment. The patients' age and sex, clinical indication for CBCT, region of interest (ROI), repeat examinations, specialty of the referring dentist, field-of-view (FOV), tube voltage (kV), tube current (mA), and radiation dose (${\mu}Gy$) were evaluated. Patients were classified by age as children (${\leq}12years$), adolescents(13-18 years), and adults(${\geq}19years$). Results: The mean age of the 526 patients was 49.4 years. The main indications were implant dentistry and dental trauma. The most frequent ROIs were posterior, while anterior ROIs were much less common. The highest percentage of repeat examinations was in children. Fifty-six percent of the referring dentists were specialists. The most commonly used FOV was small. The mean tube voltage and current were 79.8 kV and 7.4 mA for Veraview EPOC X550 and 89.9 kV and 6 mA for Veraviewepocs 3D R100, respectively. The mean doses for children, adolescents, and adults were $6.9{\mu}Gy$, $8.4{\mu}Gy$, and $7.8{\mu}Gy$, respectively. Conclusion: Although CBCT was most commonly used in adults for implant dentistry, most repeat examinations were in children, and the highest mean dose was in adolescents. Additional dose optimization efforts should be made by introducing low-dose protocols for children and adolescents.