• Journal of Radiation Protection and Research
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• 제49권1호
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• pp.1-18
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• 2024

Exponential growth has been observed in nuclear medicine procedures worldwide in the past decades. The considerable increase is attributed to the advance of positron emission tomography and single photon emission computed tomography, as well as the introduction of new radiopharmaceuticals. Although nuclear medicine procedures provide undisputable diagnostic and therapeutic benefits to patients, the substantial increase in radiation exposure to nuclear medicine patients raises concerns about potential adverse health effects and calls for the urgent need to monitor exposure levels. In the current article, model-based internal dosimetry methods were reviewed, focusing on Medical Internal Radiation Dose (MIRD) formalism, biokinetic data, human anatomy models (stylized, voxel, and hybrid computational human phantoms), and energy spectrum data of radionuclides. Key results from many articles on nuclear medicine dosimetry and comparisons of dosimetry quantities based on different types of human anatomy models were summarized. Key characteristics of seven model-based dose calculation tools were tabulated and discussed, including dose quantities, computational human phantoms used for dose calculations, decay data for radionuclides, biokinetic data, and user interface. Lastly, future research needs in nuclear medicine dosimetry were discussed. Model-based internal dosimetry methods were reviewed focusing on MIRD formalism, biokinetic data, human anatomy models, and energy spectrum data of radionuclides. Future research should focus on updating biokinetic data, revising energy transfer quantities for alimentary and gastrointestinal tracts, accounting for body size in nuclear medicine dosimetry, and recalculating dose coefficients based on the latest biokinetic and energy transfer data.

• Nuclear Engineering and Technology
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• 제38권4호
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• pp.327-342
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• 2006

Radiation therapy is an important part of cancer treatment in which cancer patients are treated using high-energy radiation such as x-rays, gamma rays, electrons, protons, and neutrons. Currently, about half of all cancer patients receive radiation treatment during their whole cancer care process. The goal of radiation therapy is to deliver the necessary radiation dose to cancer cells while minimizing dose to surrounding normal tissues. Success of radiation therapy highly relies on how accurately 1) identifies the target and 2) aim radiation beam to the target. Both tasks are strongly dependent of imaging technology and many imaging modalities have been applied for radiation therapy such as CT (Computed Tomography), MRI (Magnetic Resonant Image), and PET (Positron Emission Tomogaphy). Recently, many researchers have given significant amount of effort to develop and improve imaging techniques for radiation therapy to enhance the overall quality of patient care. For example, advances in medical imaging technology have initiated the development of the state of the art radiation therapy techniques such as intensity modulated radiation therapy (IMRT), gated radiation therapy, tomotherapy, and image guided radiation therapy (IGRT). Capability of determining the local tumor volume and location of the tumor has been significantly improved by applying single or multi-modality imaging fur static or dynamic target. The use of multi-modality imaging provides a more reliable tumor volume, eventually leading to a better definitive local control. Image registration technique is essential to fuse two different image modalities and has been In significant improvement. Imaging equipments and their common applications that are in active use and/or under development in radiation therapy are reviewed.

• 센서학회지
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• 제27권4호
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• pp.232-236
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• 2018

A radiation detection sensor was developed and characterized by combining three types of CsI(Tl) scintillators and an array-type SiPM to detect the radioactive contamination of discharged water in real time. The characterization results showed that type 3 exhibited the most desirable characteristics in response linearity (R-square: 0.97889) according to detection sensitivity and incident radiation dose. Furthermore, in terms of spectral characteristics, type 3 exhibited 16.54% at 0.356 MeV (the emission gamma ray energy of $^{133}Ba$), 10.28% at 0.511 MeV (the emission gamma ray energy of $^{22}Na$), 9.68% at 0.356 MeV (the emission gamma ray energy of $^{137}Cs$), and 2.55% and 4.80% at 1.173 MeV and 1.332 MeV (the emission gamma ray energies of $^{60}Co$), respectively. These measurements confirmed the good energy characteristics. The results were used to evaluate the spectral characteristics and energy linearity in a mixed source using type 3 with the best detection characteristics. It was confirmed that the gamma ray peaks of $^{133}Ba$, $^{22}Na$, $^{137}Cs$, and $^{60}Co$ were well resolved. Moreover, it was confirmed that R-square, which is an indicator of energy linearity, was 0.99986. This indicates a good linearity characteristic. Based on this study, further commercialization studies will contribute to measurements in real time and to the management of the contamination caused by radioactive wastewater or radioactive material leakage, which originate from facilities that use radioactive isotopes or care facilities.

• 대한기계학회논문집B
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• 제31권9호
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• pp.790-798
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• 2007

An experimental study was performed to investigate the effects of mixing quality, inlet pressure, nozzle diameter on CO, NO emission and radiation characteristics in porous ceramic fiber radiant burners. Observations of combustion characteristics occurring inside the burner system which was insulated fiber mat, were investigated by measuring emission and radiation characteristics. Combustion was achieved at the firing rate of $88{\sim}99\;kcal/hr$, inlet pressure of $100{\sim}250mmH_2O$. The fiber burner exhibit significant both spectral intensity peaks in the bands at $2.5{\mu}m\;and\;4.0{\mu}m$ relatively. There is a small difference in the variable mixing tube. However spectral intensity increased with the firing rate. CO emissions were found to be strongly dependent on the operating conditions. There was a tendency that CO concentration increased as the firing rate increases. the reason for rise of CO concentration is that is becomes it the relatively rich condition. Relatively low NO emission was observed for the whole operating range. The NO concentration is maximal at the firing rate of approximately 2850 kcal/hr and an air ratio of about 1.

• Nuclear Engineering and Technology
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• 제55권6호
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• pp.2018-2025
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• 2023

In our previous study, we proposed an integrated PG-PET-based imaging method to increase the prediction accuracy for patient dose distributions. The purpose of the present study is to experimentally validate the feasibility of the PG-PET system. Based on the detector geometry optimized in the previous study, we constructed a dual-head PG-PET system consisting of a 16 × 16 GAGG scintillator and KETEK SiPM arrays, BaSO₄ reflectors, and an 8 × 8 parallel-hole tungsten collimator. The performance of this system as equipped with a proof of principle, we measured the PG and positron emission (PE) distributions from a 3 × 6 × 10 cm³ PMMA phantom for a 45 MeV proton beam. The measured depth was about 17 mm and the expected depth was 16 mm in the computation simulation under the same conditions as the measurements. In the comparison result, we can find a 1 mm difference between computation simulation and measurement. In this study, our results show the feasibility of the PG-PET system for in-vivo range verification. However, further study should be followed with the consideration of the typical measurement conditions in the clinic application.

• Journal of Radiation Protection and Research
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• 제13권1호
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• pp.42-54
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• 1988

1988년 4월 10일부터 17일까지 오스트레일리아의 Sydney에서 개최된 제7차 IRPA 국제학회에서 발표된 방사선방어에 관한 연구논문들을 전반적으로 검토하여 방사선 연구의 동향을 파악하는 한편, 전리방사선 안전분야에서 일어나고 있는 변화와 비전리 방사선 영역에서 증가되고 있는 관심사항등을 소개함으로써 금번 제7차 IRPA 국제학회의 면모를 소개한다. 첨가하여 IRPA 7 국제학회의 poster session에서 발표된 연구논문, '황산망간 용액조 방법에 의한 Cf-252 중성자 선원의 방출률측정'이 전재된다.

• 한국방사선학회논문지
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• 제14권6호
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• pp.725-731
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• 2020

구(sphere)형의 섬광체를 사용한 방사선 스펙트로스코피 검출기를 설계하였고, 여러 대의 검출기를 사용하여 방사선원의 위치를 추적하는 시스템을 개발하였다. 방사선원의 위치 추적은 방사선의 수는 거리의 역자승 법칙에 따라 감소하는 이론을 바탕으로 위치 추적 알고리듬을 설계하였으며, 여러 위치의 방사선원에서 발생된 방사선의 수를 측정하여 알고리듬을 통해 위치를 계산하였다. 방사선원에서 발생되는 방사선은 각 검출기에서 서로 다른 계수로 검출되며, 이러한 검출되는 계수의 차이는 거리의 역자승에 비례하여 달라진다. 설계한 방사선원 위치 추적 시스템의 성능을 검증 및 평가하기 위해 Geant4 Application for Tomographic Emission (GATE) 시뮬레이션을 실시하였으며, 서로 다른 위치에 놓이 방사선원에서 발생된 방사선을 각 검출기로 계수하였다. 측정된 방사선의 수는 방사선원 위치 추적 알고리듬을 통해 위치가 추적되었으며, 실제 방사선원의 위치와 알고리듬으로 계산된 위치와의 오차를 평가하였다. 실제 방사선원의 위치와 계산된 위치와의 오차는 평균 X축 0.11%, Y축 0.37%로 측정되었으며, 매우 정확하게 위치를 측정할 수 있음이 검증되었다.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2016년도 제50회 동계 정기학술대회 초록집
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• pp.433-433
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• 2016

Carbon nanotubes (CNT) emitter has widely become an attractive mechanism that draws growing interests for cold cathode field emission. CNT yarns have demonstrated its potential as excellent field emitters. It was demonstrated that a small focal spot size was achieved by manipulating some electrical parameters, such as applied bias voltage at the mesh gate, and electrostatic focal lenses, geometrical parameters, such as axial distances of the anode, and the electrostatic focal lens from the cathode assembly, and the dimension of the opening of the electrostatic lens. Electrical-optics software was used to systematically investigate the behavior of the electron beam trajectory when the aforementioned variables were manipulated. The results of the experiment agree with the theoretical simulation results. Each variable has an individual effect on the electron beam focal spot size impinging on the target anode. An optimum condition of the parameters was obtained producing good quality of X-ray images. Also, MWCNT yarn was investigated for field emission characteristics and its contribution in the X-ray generation. The dry spinning method was used to fabricate MWCNT yarn from super MWCNTs, which was fabricated by MW-PECVD. The MWCNT yarn has a significant field emission capability in both diode and the triode X-ray generation structure compared to a MWCNT. The low-voltage-field emission of the MWCNT yarn can be attributed to the field enhancing effect of the yarn due to its shape and the contribution of the high-aspect-ratio nanotubes that protrude from the sides of the yarn. Observations of the use of filters on the development of X-ray images were also demonstrated. The amount of exposure time of the samples to the X-ray was also manipulated. The MWCNT yarn can be a good candidate for use in the low voltage field emission application of X-ray imaging.

• 한국연소학회지
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• 제7권1호
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• pp.8-14
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• 2002

Measurements of global emissions, flame radiation and flame dimensions are presented for unconfined turbulent-jet and precessing-jet diffusion flames. Precessing jet flames are characterised by increases in global flame radiation and global flame residence time for methane and propane fuels, however a strong dependency of the NOx emission indices on the fuel type exists. The fuel type dependence is considered to be because soot radiation is more effective than gas-radiation at reducing global flame temperatures relative to adiabatic flame temperatures and reducing the NO production rate.

• Radiation Oncology Journal
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• 제36권4호
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• pp.254-264
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• 2018

This article reviewed new trends and controversial issues, including the intensification of chemotherapy and recent brachytherapy (BT) advances, and also reviewed recent consensuses from different societies on the management of locally advanced cervical cancer (LACC). Intensive chemotherapy during and after radiation therapy (RT) was not recommended as a standard treatment due to severe toxicities reported by several studies. The use of positron emission tomography-computed tomography (PET-CT) and magnetic resonance imaging (MRI) for pelvic RT planning has increased the clinical utilization of intensity-modulated radiation therapy (IMRT) for the evaluation of pelvic lymph node metastasis and pelvic bone marrow. Recent RT techniques for LACC patients mainly aim to minimize toxicities by sparing the normal bladder and rectum tissues and shortening the overall treatment time by administering a simultaneous integrated boost for metastatic pelvic lymph node in pelvic IMRT followed by MRI-based image guided adaptive BT.