• 대한의생명과학회지
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• 제19권4호
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• pp.338-343
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• 2013

Serum levels of alkaline phosphatase (ALP) are widely used in the clinical diagnosis of hepatic diseases and the assessment of liver status. They also have epidemiological significance to be prospective risk factors for bone diseases, such as osteitis deformans, rickets, osteomalacia, hyperparathyroidism, healing fractures, and osteoblastic bone tumors. In the previous study, single nucleotide polymorphisms (SNPs) in several genes have been reported to be associated with serum levels of liver enzyme in American population. We aimed to confirm whether the genetic variation of RETNLB (resistin like beta) gene also influence the serum levels of liver enzyme in Korean population. We genotyped variants in or near RETNLB in a population-based sample including 994 Korean adults. Here, we performed association analysis to elucidate the possible relations of genetic polymorphisms in RETNLB gene with serum levels of liver enzyme. By examining genotype data of a total of 944 subjects in 5 hospital health promotion centers, we discovered the RETNLB gene polymorphisms are associated with serum levels of ALP. The common and highest significant polymorphism was rs736327 (${\beta}$=8.66, P=2.37E-05), rs7639070 (${\beta}$=8.56, P=3.24E-05) with ALP in all groups. Furthermore, the ALP was consistently associated with rs736327 (${\beta}$=10.40, P=5.23E-05), rs7639070 (${\beta}$=10.32, P=6.74E-05) in the male population. Consequently, we found statistically significant SNPs in RETNLB gene that are associated with serum levels of ALP. In addition, these results suggest that the individuals with the minor alleles of the SNP in the RETNLB gene may have elevated serum levels of ALP in the Korean population.

• 한국항해항만학회:학술대회논문집
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• 한국항해항만학회 2006년도 International Symposium on GPS/GNSS Vol.1
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• pp.221-226
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• 2006

Around 2002, the United States Coast Guard (USCG) identified a need to re-capitalize their Reference Station (RS) and Integrity Monitor (IM) equipment used in the Nationwide Differential Global Position System (NDGPS). Commercially available off-the-shelf differential RS and IM equipment lacked the open architecture required to support long-term goals that include future system improvements such as use of new civil frequencies on L2 and L5 and realization of a higher rate NDGPS beacon data channel intended to support RTK. The first step in preparing for this future NDGPS was to port current RTCM SC-104 compatible RS and IM functionality onto an open architecture PC-based platform. Trimble's product Charisma is a PC-based RS and IM software designed to meet these USCG goals. In fact USCG engineers provided key designs and design insights throughout the development. We cannot overstate the contribution of the USCG engineers. Fundamental requirements for this effort were that it be sufficiently flexible in hardware and software design to support fluid growth and exploitation of new signals and technologies as they become available, yet remain backward compatible with legacy user receivers and existing site hardware and system architecture. These fundamental goals placed an implicit adaptability requirement on the design of the replacement RS and IM. Additionally, project engineers were to remain focused on sustaining the high level of differential GPS service that 1.5 million legacy users have come to depend on. This paper will present new hardware and software (i.e., Trimble's Charisma software) architecture for the next generation NDGPS RS and IM. This innovative approach to engineering on an open architecture PC-based platform allows the system to continue to fulfill legacy NDGPS system requirements and allows the USCG and others to pursue a scalable hardware re-capitalization strategy. We will use the USCG's recapitalization project to explain the essential role of the Charisma software.

• 한국식품과학회지
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• 제34권3호
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• pp.431-436
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• 2002

보통 옥수수 전분을 이용하여 저항전분을 제조할 때 저항 전분의 수율을 높일 수 있는 방법을 개발하기 위한 목적으로 가교결합 전분을 제조하고 annealing처리를 병행하였다. Annealing은 $40{\sim}60^{\circ}C$ 범위에서 실시하였고, 이와 비교하기 위하여 $70^{\circ}C$와 $100^{\circ}C$에서 열처리한 후 가교결합 전분을 제조하였다. RS 분석방법으로는 pancreain-gravimetric법(P/G법)을 사용하였다. 보통 옥수수전분과 고아밀로오스 옥수수전분으로 annealing하지 않고 가교결합 전분을 제조했을 때의 RS수율은 각각 14.7, 45.3%였고, annealing 한 후 가교결합 전분을 제조했을 때 28.0, 63.4%까지 증가하였다. 가교결합 전분의 팽윤력은 annealing 처리에 의해 영향받지 않았으나, 보통 옥수수전분으로 제조한 시료의 경우는 호화온도이상에서 열처리했을 때 팽윤력이 2배이상 증가하였다. 두가지 전분으로부터 제조된 가교결합 전분의 X-선 회절도와 주사전자현미경에 의한 특성 역시 annealing에 의해 영향받지 않았다.

• The Plant Pathology Journal
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• 제20권4호
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• pp.289-292
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• 2004

The population of Ralstonia solanacearum (Rs) in soil is very important as a primary inoculum source of bacterial wilt in tobacco fields. To investigate the population of Rs, physical properties and chemical components during the tobacco growing season, soil samples were taken from the fifteen fields which were located in the flue-cured tobacco growing area, Ansung, Kyunggi province and Wonju, Kangwon province. Two fields of the fifteen were bacterial wilt free. Six fields had less than 10% plants being diseased and seven over 10%. The Rs population level determined by using SMSA medium generally showed an up-and-down pattern being low in May, high in Jun and July and low in August. The soil population in May and June showed a positive correlation with the incidence of bacterial wilt (r=0.571$^*$, r=0.688$^{**}$), but P$_2O_5$, content of soil was negatively correlated with the disease incidence (r=-0.539$^*$). These results suggest that Rs population in soil examined in May or in June, and the P$_2O_5$ content in soil should be key factors to determine the bacterial wilt potential of tobacco fields.

• Journal of Life Science
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• 제9권1호
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• pp.14-16
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• 1999

Genetic variability was monitored by random amplified polymorphic DNA-polymerase chain reaction (RAPD-PCR) in dicofol-susceptible (S), dicofol-resistant (R) and its reverse-selected (RS) strains of two-spotted spider mite, of Tetranychus urticae. Before the reverse-selection, RS strain, selected reversely from R strain, was 23-fold resistance ratio at {TEX}$LC_{50}${/TEX} to S strain. The resistance was started to in incline slowly to the resistance level of S strain after one year, and the resistance ratio was 4-fold in the 7 years after then. PCR-amplification of T. urticae DNA showed polymorphism in the amplifications with 12 primers in 100 kinds of arbitrary DNA sequences. RAPD amplification with primer OPR-12 (5`-ACAGGTGCGT-3`) showed amplified bands at 1,000 base pair in the S-and RS-strain, and at 350 base pair in R-strain. The results of polymorphism are genetic variabilities derived from development and selection of resistance in each strain. The peculiarly amplified fragments were guessed to participate in dicofol resistance. From the analysis of genetic similarity, it is inferred the gene composition of S-and RS-strain is much closer than that of R-strain.

• Asian Pacific Journal of Cancer Prevention
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• 제15권6호
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• pp.2663-2667
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• 2014

Background: Single nucleotide polymorphisms of C-reactive protein (CRP) have been shown to be related to circulating CRP level, risk and prognosis in cancer patients. However, accumulating evidence of rs1800947 involvement in risk of cancer is inconsistent. Thus, a meta-analysis was performed to obtain a more precise relationship. Materials and Methods: The pooled odds ratio (OR) and its 95% confidence interval were assessed in 10 eligible articles with 12 studies containing 5,601 cancer cases and 8,669 cancer-free controls. Results: No significant association was observed overall and in subgroups in comparison of genotype GC vs GG ($P_H$=0.847, OR=0.939, 95%CI=0.810-1.087), GC/CC vs GG ($P_H$=0.941, OR=1.021, 95%CI=0.901-1.157) and allele C vs G ($P_H$=0.933, OR=1.026, 95%CI=0.909-1.159). However, statistically significance was evident in comparison of genotype CC vs GG in cancer risk ($P_H$=0.586, OR=2.854, 95%CI= 1.413-5.763), especially in colorectal cancer ($P_H$=0.481, OR=4.527, 95%CI= 1.664- 12.315). Conclusions: Genotype CC of rs1800947 in the CRP gene is strongly associated with increased cancer risk, particularly in colorectal cancer.

• Asian Pacific Journal of Cancer Prevention
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• 제13권7호
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• pp.3483-3488
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• 2012

Objective: Several studies have demonstrated associations between the TERT rs2736098 single nucleotide polymorphisms (SNPs) and susceptibility to cancer development. However, there are conflicting results. A systematic meta-analysis was therefore performed to establish the cancer risk associated with the polymorphism. Methods: In this meta-analysis, a total of 6 case-control studies, including 5,567 cases and 6,191 controls, were included. Crude odds ratios with 95% confidence intervals were used to assess the strength of associations in several genetic models. Results: Our results showed no association reaching the level of statistical significance for overall risk. Interestingly, in the stratified analyses (subdivided by ethnicity), significantly increased risks were found in the Asian subgroup which indicates the TERT rs2736098 polymorphism may have controversial involvement in cancer susceptibility. Conclusions: Overall, this meta-analysis indicates that the TERT rs2736098 polymorphism may have little involvement in cancer susceptibility.

• 한국통신학회논문지
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• 제18권10호
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• pp.1495-1507
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• 1993

본 논문에서 마이크로프로그램 제어방식을 이용하여 CDP(Compact Disc Player)에서 사용되는 RS 부호(Reed-Solomon code)의 복호기를 설계하였다. 사용한 복호방법은 Newton 항등식들로 부터 얻어진 연립방정식들을 이용하여 오류위치다항식의 계수들을 구하고, C2(외부호)복호에서의 소실데이타 개수를 확인한다. 또한 C2복호에서 소실데이타 값들을 C1(내부호)복호 결과와 신드롬들을 이용하여 구한다. 이와 같은 복호방법을 이용하여 4개의 소실정정까지 할 수 있도록 해서 오류정정능력을 높였다. 설계한 복호기는 오류정정에 필요한 GF(28)상에서 연산을 수행할 수 있는 복호연산기와 프로그램 ROM을 가지고있는 복호제어기 띤 마이크로명령어(microinstruction)들로 구성된다. 마이크로명령어들을 이용하여 RS부호의 복호 알고리즘을 프로그램할 수 있으며, 성능향상이나 다른 용도에 사용하기 위해서는 프로그램 ROM만 바꾸면 가능하므로 간편하다. 본 논문에서 설계한 복호기는 Verilog HDL의 Logic Level Modeling을 이용하여 구현했으며, 설계된 복호기에서 각 마이크로명명령어들은 14비트(=1 word)이고, 프로그램 ROM의 크기는 360 word이다. 또한 C1과 C2를 모두 복호하는데 걸리는 최대시간은 424 clock-cycle이다.

• 한국환경과학회지
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• 제19권6호
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• pp.671-680
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• 2010

The present study evaluated residential exposure to atmospheric formaldehyde and acetaldehyde according to distance from the a dyeing industry complex (DIC). This purpose was achieved by measuring concurrently the outdoor air concentrations in residences near the DIC and a certain distance away, plus the outdoor air concentrations at two industrial areas within the DIC boundary. Formaldehyde concentrations (median values of 24.3 and $22.5{mu}g/m^3$ in IS1 and IS2, respectively) were higher than acetaldehyde concentrations (median values of 7.4 and $7.3{mu}g/m^3$ in IS1 and IS2, respectively) at both sites. However, there was no significant difference in the industrial outdoor air concentrations of both formaldehyde and acetaldehyde between the two sites. In addition, the median formaldehyde concentration from the residential site near the DIC (RS1) was about 1.5 times higher than that from the residential site far away from the DIC(RS2), and the median acetaldehyde concentration from RS1 was about 1.3 times higher than that from RS2. It is noteworthy that the mean or median risk as well as these maximum risks are well above the USEPA's permissible risk level of $10^{-6}$ from environmental exposure. This suggests that appropriate management for formaldehyde and acetaldehyde is necessary in order to decrease risk of the residents of study areas, regardless of the distance from the DIC.

• Agribusiness and Information Management
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• 제9권1호
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• pp.7-17
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• 2017

Agricultural water management has gained enormous attention in the developing world to alleviate poverty, reduce hunger and conserve ecosystems in small-scale production systems of resource-poor farmers. The story of food security in the $21^{st}$ century in India is likely t o be closely linked to the story of water security. Today, the water resource is under severe threat. The past experiences in India in general and in Andhra Pradesh in particular, indicated inappropriate management of irrigation has led to severe problems like excessive water depletion, reduction in water quality, water logging, salinization, marked reduction in the annual discharge of some of the rivers, lowering of ground water tables due to pumping at unsustainable rates, intrusion of salt water in some coastal areas etc. Considering the importance of irrigation water resource efficiency, Krishna Western Delta (KWD) of Andhra Pradesh was purposively selected for this in depth study, as the farming community in this area are severely affected due to severe soil salinity and water logging problems and hence, adoption of different water saving crop production technologies deserve special mention. It is quite disappointing that, canals, tube wells and filter points and other wells could not contribute much to the irrigated area in KWD. Due to less contribution from these sources, the net area irrigated also showed declining growth at a rate of -6.15 per cent. Regarding paddy production, both SRI and semi-dry cultivation technologies involves less irrigation cost (Rs. 2475.21/ha and Rs. 3248.15/ha respectively) when compared to transplanted technology (Rs. 4321.58/ha). The share of irrigation cost in Total Operational Cost (TOC) was highest for transplanted technology of paddy (11.06%) followed by semi-dry technology (10.85%) and SRI technology (6.21%). The increased yield and declined cost of cultivation of paddy in SRI and semi-dry production technologies respectively were mainly responsible for the low cost of production of paddy in SRI (Rs. 495.22/qtl) and semi-dry (Rs. 532.81/qtl) technologies over transplanted technology (Rs. 574.93/qtl). This clearly indicates that, by less water usage, paddy returns can be boosted by adopting SRI and semi-dry production technologies. Both the system-level and field-level interventions should be addressed to solve the issues/problems of water management. The enabling environment, institutional roles and functions and management instruments are posing favourable picture for executing the water management interventions in the State of Andhra Pradesh in general and in KWD in particular. This facilitates the farming community to harvest good crop per unit of water resource used in the production programme. To achieve better results, the Farmers' Organizations, Water Users Associations, Department of Irrigation etc., will have to aim at improving productivity per unit of water drop used and this must be supported through system-wide enhancement of water delivery systems and decision support tools to assist farmers in optimizing the allocation of limited water among crops, selection of crops based on farming situations, and adoption of appropriate alternative crops in drought years.