• Title/Summary/Keyword: ROC곡선

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Differential Diagnosis of Benign and Malignant Thyroid Nodules Using the K-TIRADS Scoring System in Thyroid Ultrasound (갑상샘 초음파 검사에서 K-TIRADS 점수화 체계를 사용한 양성과 악성 갑상샘 결절의 감별진단)

  • An, Hyun;Im, In Cheol;Lee, Hyo-Yeong
    • Journal of the Korean Society of Radiology
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    • v.13 no.2
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    • pp.201-207
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    • 2019
  • This study has evaluated whether the method of using the combination of different risk group, according to K-TIRADS classification and K-TIRADS classification in thyroid ultrasonography is useful in a differential diagnosis of benign and malignant nodules. The subject was patients underwent thyroid ultrasonography and retrospective analysis were performed based on the results of fine needle aspiration cytology. A chi-square test was performed for the difference analysis of the score system in K-TIRADS and different risk group according to the benign and malignant of thyroid nodule. The optimized cut off value was determined by the K-TIRADS score and different risk group to predict malignant nodule through ROC curve analysis. In the differential verification result of K-TIRADS and different risk group, according to the classification of benign and malignant nodule group each showed significant difference statistically(p=.001). In the point classification according to K-TIRADS for the prediction of benign and malignant in ROC curve analysis showed AUC 0.786, Cut-off value>2(p=.001), and in the different risk group, it was decided as AUC 0.640, Cut-off value>2(p=.001). When discovering the nodule in thyroid ultrasound, it is considered that the K-TIRADAS which helps in identifying benign and malignant thyroid nodules, it is considered to be helpful in the differential diagnosis of thyroid nodules, than the classification system according to Different risk group, and when applying the classification system according to K-TIRADS, it is considered that it can reduce unnecessary fine needle aspiration cytology and could be helpful in finding the malignant nodules early.

Evaluation of convergence Elasticity of Liver Fibroscan used measurement with Ultrasonography (초음파를 이용한 간 섬유화 스캔 검사의 융합 탄성도 측정 평가)

  • Kim, Min-Jeong;Han, Man-Seok;Jang, Jae-Uk
    • Journal of the Korea Convergence Society
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    • v.8 no.5
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    • pp.79-85
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    • 2017
  • The purpose of this research was to evaluate the clinical and the instrument of convergence utility of transient elastography (FibroScan(R):electromagnetic wave) in diagnosing and treating liver ailments through a comparison and an analysis between liver function blood test and transient elastography (FibroScan(R)) in patients with chronic hepatitis B virus infection. Of all the patients with chronic hepatitis B virus infection who visited clinic B in Daejeon City between July 1, 2015, and February 28, 2016, 75 who underwent a FibroScan(R) test were selected for this study. Their laboratory and liver function test results were compared for a correlation analysis before constructing an ROC (Receiver Operation Characteristic) curve. Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) levels were 0.572 and 0.502, respectively, and showed highest correlation with fibrosis score, with statistical significance (p<0.000). Gamma glutamyltranspeptidase, total bilirubin, and alkaline phosphatase levels also showed relatively significant correlations in this order of sequence, while -fetoprotein and total protein levels did not show any statistically significant values. Albumin (-0.449) and platelet levels (-0.373) showed negative correlations with each other and no correlation with fibrosis score (p < 0.000). As liver fibrosis worsened, the accuracy of the ROC curve increased. At the F4 stage, which is the cirrhotic stage, the largest area under the curve was observed. FibroScan(R) showed significant correlation with the ALT (serum glutamic pyruvic transaminase) and AST (serum glutamic oxaloacetic transaminase) levels in the liver function test, which is a routine test for patients with chronic liver ailments. This implies that fibrosis correlates with liver inflammation severity.

Comparison of the Usefulness of Lipid Ratio Indicators for Prediction of Metabolic Syndrome in the Elderly Aged 65 Years or Older (65세 이상 고령자에서 대사증후군 예측을 위한 지질비율 지표의 유용성 비교)

  • Shin, Kyung-A;Kim, Eun Jae
    • Journal of the Korea Convergence Society
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    • v.13 no.1
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    • pp.399-408
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    • 2022
  • The purpose of this study was to compare the usefulness of the lipid ratio indicators for the diagnosis of metabolic syndrome in the elderly aged 65 years or older. From January 2018 to December 2020, 1,464 people aged 65 years or older who underwent a health checkup at a general hospital in Seoul were included. Lipid ratio indicators were measured through blood tests. The prevalence of metabolic syndrome according to the quartiles of the lipid ratio index was confirmed by logistic regression analysis. In addition, the metabolic syndrome predictive ability and cutoff value of the lipid ratio indices were estimated with the receiver operating characteristic(ROC) curve. The correlation between atherogenic index of plasma(AIP) and waist circumference was the highest in both men and women(r=0.278, p<0.001 vs r=0.252, p<0.001). As for the lipid ratio indices, the incidence of metabolic syndrome was higher in the fourth quartile than in the first quartile. The area under the ROC curve(AUC) value of AIP was higher at 0.826(95% CI=0.799-0.850) and 0.852(95% CI=0.820-0.881) for men and women, respectively, compared to other lipid ratio indicators, and the optimal cutoff values for both men and women was 0.44(p<0.001). Therefore, the AIP among the lipid ratio indicators was found to be the most useful index for diagnosing metabolic syndrome in the elderly aged 65 years or older.

Computer Aided Diagnosis Applications for the Differential Diagnosis of Infarction: Apply on Brain CT Image (뇌경색 감별진단을 위한 컴퓨터보조진단 응용: Brain CT Images 적용)

  • Park, Hyong-Hu;Cho, Mun-Joo;Im, In-Chul;Lee, Jin-Soo
    • Journal of the Korean Society of Radiology
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    • v.10 no.8
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    • pp.645-652
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    • 2016
  • In this study, based on the analysis of texture feature values of statistical properties. And we examined the normal and the applicability of the computer-aided diagnosis of cerebral infarction in the brain computed tomography images. The experiment was analyzed to evaluate the ROC curve recognition rate of disease using six parameters representing the feature values of the texture. As a result, it showed average mean 88%, variance 92%, relative smoothness 94%, uniformity of 88%, a high disease recognition rate of entropy 84%. However, it showed a slightly lower disease recognition rate and 58% for skewness. In the analysis using ROC curve, the area under the curve for each parameter indicates 0.886 (p = 0.0001) or more, resulted in a meaningful recognition of the disease. Further, to determine the cut-off values for each parameter are determined to be the prediction of disease through the computer-aided diagnosis.

Medical Image Restoration by Digital Image Processing (디지털영상처리를 이용한 의료영상복원)

  • Lee, Won-Seok;Chung, Kil-Soo;Lee, Yong-Gu
    • 전자공학회논문지 IE
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    • v.49 no.2
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    • pp.75-81
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    • 2012
  • In this paper, restoration methods were applied to restore analog medicine images with an aged image added and then blurred by noises. To restore the aged image blurred by the blurring function and added by noises, it was applied to the restoration methods which are inverse filtering and wiener filtering which are linear restoration techniques and Lucy-Richardson's algorithm which is nonlinear restoration technique. Moreover, ROC curve, a subjective evaluation method, was applied to evaluate the image quality of the restoration image. The wiener filtering using the ratio of constants acquired better image than the inverse filtering, but both of them couldn't improve ability to make a diagnosis. The restoration image applied to Lucy-Richardson algorithm was the best performance of the applied techniques and its sensitivity and specitivity were improved by 15[%] as much performance as the original aged image.

Neuropsychology of Attention (주의력의 신경심리학)

  • Kim, Chang-Yoon;Kim, Seong-Yoon
    • Sleep Medicine and Psychophysiology
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    • v.6 no.1
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    • pp.26-31
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    • 1999
  • "Attention" is not defined sufficiently. This term incorporates several dimensions or complex information processes such as alertness, spatial distribution, focused attention, sustained attention, divided attention and supervisory attentional control. In practice, however, various aspects of attention cannot be assessed separately with a single test. Moreover, a particular test is never assessing attention only, because the several intervening variables may influence the attentional component. Therefore, one can only assess a certain aspect of human behavior with special interest for its attentional component. This paper attempted to clarify various concepts of attention, reviewed signal detection theories with receiver operating characteristic(ROC) curves, and listed practical methods for assessment of attention.

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A Single Channel Voice Activity Detection for Noisy Environments Using Wavelet Packet Decomposition and Teager Energy (웨이블렛 패킷 변환과 Teager 에너지를 이용한 잡음 환경에서의 단일 채널 음성 판별)

  • Koo, Boneung
    • The Journal of the Acoustical Society of Korea
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    • v.33 no.2
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    • pp.139-145
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    • 2014
  • In this paper, a feature parameter is obtained by applying the Teager energy to the WPD(Wavelet Packet Decomposition) coefficients. The threshold value is obtained based on means and standard deviations of nonspeech frames. Experimental results by using TIMIT speech and NOISEX-92 noise databases show that the proposed algorithm is superior to the typical VAD algorithm. The ROC(Receiver Operating Characteristics) curves are used to compare performance of VAD's for SNR values of ranging from 10 to -10 dB.

Clinical Significance of Creatine Kinase MB mass and Cardiac Troponin I as a Marker of Perioperative Myocardial Infarction After Coronary Artery Bypass Grafting (관상동맥 우회술 후 심근경색의 표지자로서 Creatine Kinase MB 농도와 Cardiac Troponon I의 임상적 의의)

  • 이재진;김응중;이원용;신윤철;지현근
    • Journal of Chest Surgery
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    • v.35 no.1
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    • pp.27-35
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    • 2002
  • Background: A perioperative myocardial infarction(PMI) is one of the major complications after CABG. Among diagnostic methods of PMI, CK-MB activity assays have been increasingly replaced by CK-MB mass assays, which have more sensitive, simple measurement. Also, new cardiac-specific and -sensitive marker, cardiac troponin I(cTnl), has been shown to be a marker of myocardial infarction. We report our evaluation of clinical significance of CK-MB mass and cTnl as a marker of PMI after CABG. Material and Method: We studied 32 patients who underwent CABG at Kangdong Sacred Hospital between April 2000 and April 2001. Postoperative serum CK-MB activity level, serum CK-MB mass, cTnl, electrocardiogram, echocardiogram, and clinical data were recorded prospectively The diagnosis of PMI was defined as positive 2 among 3 or all of the following , by a new Q wave on the electrocardiogram, by serum CK-MB activity higher than 200 lU/L within 72 hours after operation, and by new regional wall motion abnormality on the echocardiogram. Result: After CABG, 3 patients had sustained a PMI according to current diagnostic criteria. As serum CK-MB activity time course, a level of CK-MB activity 12 hours after CABG had very linear correlated significance with serum CK-MB mass 24hours(R=0.946) and cTnl 48 hours(R=0.933) after CABG(p=0.000). As we used a receiver operating characteristics curve(ROC curve) for a diagnostic cutoff value in patients with PMI, serum CK-MB mass levels higher than 30.05 ug/L 24 hours after CABG detected the presence of PMI with an area under the ROC curve of 1.0, a sensitivity of 100%, a specificity of 100%, a positive predictive value of 100%, and a negative predictive value of 100%. Also serum cTnl levels higher than 17.15 ug/L 48 hours after CABG detected the presence of PMI with an area under the ROC curve of 0.98, a sensitivity of 100%, a specificity of 96.6%, a positive preclictive value of 75%, and a negative predictive value of 100% Conclusion: We concluded that both the measurement of CK-MB mass and cTnl are the easier, accurate methods as a diagnostic marker of PMT after CABG, also as a proposal of diagnostic cutoff value enables to an early detection of PMI. However, a 1arger number of patient will be needed because of statistic limitation that a small number of participating patients, a small number of PMI.

A Validation of The Korean Version of Eating Attitude Test-26 (한국판 식사태도검사-26(The Eating Attitude Test-26 : KEAT-26) 의 타당화)

  • Rhee, Min-Kyu;Go, Young-Taek;Lee, Hye-Kyung;Whang, Eul-Ji;Lee, Young-Ho
    • Korean Journal of Psychosomatic Medicine
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    • v.9 no.2
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    • pp.153-163
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    • 2001
  • This study was attempted to investigate the discriminant validity of Korean version of Eating Attitude Test-26(KEAT-26) and to provide the sensitivity, specificity and efficiency according to cutting score, which may be useful to determine the optimal cutoff point on various purposes. The KEAT-26 was administered to 108 female patients with eating disorders, 179 female participants in body slimming center, 120 female athletic college students, 227 female college students, and 183 healthy normal women. Validity was tested by ANOVA and ROC curve analysis. The results revealed that the total score of the KEAT-26 showed a statistically significance between groups and that the score of the KEAT-26 of eating disorders group was significantly higher than that of the other groups in post hoc test. In comparison of the 4 subfactor score of the KEAT-26 between groups, significant differences in main effect within groups were found in all subfactors except factor IV. ROC curve analysis showed 80% of efficiency to discriminate eating disorders group from normal control group using cutoff score on maximum discriminant efficiency and 69% of efficiency to discriminate eating disorders group from high risk groups for eating disorders. Each cutoff score on maximum in efficiency was as follows ; 25 between eating disorders group and participants in body slimming center, 19 between eating disorders group and healthy normal woman, 23 between eating disorders group and athletic college students, 21 between eating disorders group and college students. Using 22(T score 65) of the KEAT-26 as the cutoff score, sensitivity was 54%, specificity was 84%, and overall efficiency was 80%. These results indicate that the KEAT-26 has a good discriminant validity in Korean population and also suggest that the KEAT-26 may be useful assessment tool to screen the disordered eating problems on clinical and epidemiological purposes.

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