• Food Science and Biotechnology
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• v.15 no.5
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• pp.694-697
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• 2006

The initiation of immunoglobulin E (IgE)-mediated allergic reactions requires binding of IgE antibody to its high-affinity receptor. Human basophilic KU812F cells express $Fc{\varepsilon}RI$ on the cell surface and act as effector cells in the allergic response. In this study, we investigated the effects of Scutellaria radix extract on the expression of the $Fc{\varepsilon}RI$ in human KU812F cells. Flow cytometric analysis showed that S. radix extract treatment caused a concentration-dependent decrease in $Fc{\varepsilon}RI$ expression on the cell surface. Furthermore, the level of $Fc{\varepsilon}RI$ ${\alpha}$, ${\beta}$, and ${\gamma}$ chain mRNA in KU812F cells was examined by RT-PCR. S. radix extract reduced total cellular $Fc{\varepsilon}RI$ $\alpha$ and ${\gamma}$ chain mRNA expression in a concentration-dependent manner. $Fc{\varepsilon}RI$-mediated histamine release was reduced from $21.75{\pm}1.34\;ng/10^6$ cells in non-treated cells to $16.46{\pm}1.98\;ng/10^6$ cells in S. radix extract treated cells. These results suggested that S. radix extract has the potential to down-regulate of FcRI expression and to inactivate basophils.

• Journal of International Academy of Physical Therapy Research
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• v.1 no.1
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• pp.65-72
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• 2010

Supposing that somatotype evaluation results would have significant differences between the public group with less amounts of exercises and the special group with intensive exercises for three to four times a day, this study aimed at comparing the mutual consistency between the results determined by somatotype evaluation tools such as visually calculated index(VCI), R$\ddot{o}$hrer's Index(RI) and Body Mass Index(BMI). The public, taekwondo players and judo players groups were composed of fifty persons, taekwondo players and judo players passed through VCI determination, respectively. Their height and weight were examined and analyzed with somatotype evaluation tools. Comparison of somatotype dispersion of RI and VCI showed that most women were determined by VCI as lean type but were determined by RI as normal type. And that women were determined by VCI as fat type but were determined by RI as normal type. Therefore both men and women showed significant differences in VCI and RI. Comparison of somatotype dispersion of VCI and BMI showed that both men and women were overestimated or underestimated by VCI rather than by BMI. Comparison of somatotype dispersion of RI and BMI showed that men were less determined by BMI as lean type compared with women; both men and women less determined by BMI rather than by RI as normal type; and both men and women, in particular, were more determined by BMI as fat type but men were more determined by BMI rather than by RI as fat type. Total somatotype consistency by tools showed that VCI has the greatest possibility of determining the public group, compared with other groups as lean type and that the consistency of the three tools were relatively higher for the taekwondo players and judo players groups, compared with the public.

• Journal of Conservation Science
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• v.31 no.4
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• pp.489-497
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• 2015

Iron sickle is tool used in various ways and have various form. It has agricultural feature as well as is used in weapon. Previous studies have been focused on features of farming tools. In this study, metallurgical analysis of iron sickles are introduced because examples of analysis for iron sickles is rare. Two sickles form Yeongi Jangjae-ri are investigated and compared to one sickle of Yeongi Songwon-ri. Three sickles have forging molding process and heat treatment process. No.1 sickle of Jangjae-ri have martensite of quenching. No.2 sickle of Jangjae-ri was undergone high temperature as compared with others. This show manufacturing technology of sickles from Jangjae-ri in over the Songwon-ri's.

• Journal of the Korean Society of Costume
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• v.34
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• pp.195-208
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• 1997

1) The color of JOGORI and CHIMA was such gorgeous and those garments were put on during the events of GAM-EUNG-CHUNG-BAI HO-GU-GEO-RI JO-SANG-GEO-RI DEWT-JUN and CHAN-BOO-GEO-RI. 2)BULSA-JANG-SAM(JE-SUK-GEO-RI) was white colored and had wide sleeves putting on a pink priestrobe and a pink belt on it 3) they put on HONG-CHUL-NIK(GU-REUNG) and CHONG-CHUL-NIK(DAE-GEO-RI). 4)They put on GOO-GUN-BOK(JUN-RIP JUN-BOK(BYUL-SUNG-GEO-RI) DONG-DA-RI(Expel the demon) 5) MONG-DOO-RI(MAN-SIN-MAL-BYUNG) put on the garment constructed with the color and from of a white straight collar a wide sleeve and a pink belt 6) A long robe was colored with green (GAM-EUNG-CHUNG-BAI) and was used not as a headdress but as a man's overcoat. 7) CHANG-EUI was a green colored small CHAHG-EUI(SUNG-JO-GEO-RI). As observed above the Shaman apprel during Chosun Dynasty is a part of the traditional clothing originated from THE THEORY OF THE COSMIC DUAL FORCES and THEORY OF THE COSMIC DUAL FORCES and the FIVE ELEMENTS (i.e. metal wood water fire and earth) It's basic form and wearing method were not so different from the traditional clothing silmilar to the official uniform during Chosun Dynasty and the official uniform was the symbol of authority(almost almighty) at that time of period and to that the Shaman apparel was constructed with the more gorgeous colors to emphasize the sanctity or the descent of the Divine Being from heaven. We realized that a Shaman had put on the symbolic garment suitable for the grade and nature of the Divine Body at every events to enter into " The World of Gods"Gods."

• BMB Reports
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• v.31 no.2
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• pp.149-155
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• 1998

The N199H variant of the EcoRI endonuclease has about twice the catalytic activity of the wild-type. A comparison of their biochemical characteristics, using synthetic oligonucleotides 5'-dAAAACTTAAGAAAAAAAAAAA-3' (KA) and 5'-dTTTTTGAATTCTTTTTTTTTT-3' (KT), helps to define the cleavage reaction pathway of these enzymes. Both EcoRI and EcoRI variant N199H were found to cleave singlestranded KA or KT about three times faster than the double-stranded forms, although the KT oligonucleotide was more susceptible. Using the ssDNA substrate in kinetic analyses, lower $K_m$ values were obtained for the N199H variant than for the wild-type at low (50 mM), as well as high (200 mM), sodium chloride concentrations. This difference between the endonucleases is attributed to a grealter accessibility for tbe substrate by the variant, and also a higher affinity for the DNA backbone. It also appears that the relative activities of the two enzymes, particularly at high ionic strength, are proportional to their populations in the monomeric enzyme form. That is, according to gel filtration data, half of the N199H molecules exist as monomers in 200 mM NaCl, whereas those of the wild-type are mainly dimeric. Consequently, the Asp199 residue of the EcoRI endonuclease may be implicated in the protein-protein interaction leading to dimerization, as well as in coupling to DNA substrates. In summary, it is proposed that active monomeric endonuclease molecules, derived from the dimeric enzyme, recognize and form a complex with a single stranded form of the DNA substrate, which then undergoes nucleophilic substitution and cleavage.

• Journal of Veterinary Clinics
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• v.20 no.3
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• pp.274-277
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• 2003

The purpose of this study was to determine the range of resistive index(RI) of the cranial pancreaticoduodenal artery(cPDA) in the normal dog's and to assess the possibility of clinical application of RI for diagnosing a pancreatitis. Five patients with acute pancreatitis and 17 healthy adult beagle dogs were used. Duplex color Doppler ultrasonographic examination was performed by using a real-time scanner with 11-MHz linear-array transducer. The dogs were restrained in dorsal recumbency without the use of chemical agent. The mean RI of the normal pancreas(0.63$\pm$0.04) was significantly(t = 5.79, p = 0.001) different from acute pancreatitis dog(0.75$\pm$0.04). Duplex color Doppler ultrasonography was an useful technique for detecting and measuring RI of the cPDA. The evaluation of RI of the cPDA may be a valuable supportive diagnostic procedure for evaluating the pancreatitis or suspected in dogs.

• Journal of the Korean Institute of Rural Architecture
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• v.24 no.4
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• pp.17-24
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• 2022

This study aims to identify the Spatial Changes and the main agent of space creation in Samrye Area during the Japanese Occupation Period. As for the urban space in the Samrye area, the urban space was expanded to the Hujeong-ri area from the construction of the Jeonbuk light railway. Before 1914, the urban space of Samrye was formed around Samrye Station in Samrye-ri, which oversees Samrye-do from the Goryeo Dynasty to the Joseon Dynasty, but when Samrye Station of Jeonbuk light railway was established in Hujeong-ri in 1914, the foundation of a ladder-type street network visible from the central space of the current Samrye area was formed until the 1930s. And it was the Japanese and Korean landowners who took the lead in the construction of the Jeonbuk light railway, not the government, who expanded the urban space of Samnye from Samrye-ri to Hujeong-ri. The background of the establishment of Jeonbuk light railway is the reason why Dongsan Farm has difficulty in transporting rice to the Honam Line during the rice harvest. At that time, Park Ki-soon, famous as the land king, took charge of the established chairman of the railroad installation and established it, and with the establishment of Samrye Station, the access road was connected to his farm. In addition, a new road was built on the farm land that owned the Hujeong-ri area to the Seoul-Mokpo Interroad in Samrye-ri, thereby expanding the urban space. In other words, unlike Gunsan and Iksan, which were built under the leadership of the Japanese colonial eran government, the urban space in Samrye area was expanded by a farmer who grew up as a large landowner based on agriculture, which was the economic base at the time.

• Journal of Radiopharmaceuticals and Molecular Probes
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• v.6 no.1
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• pp.27-38
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• 2020

Alzheimer's disease (AD) is one of the challenging conditions that have no cure, yet early diagnosis can help to control the disease. PET imaging of tau has several advantages, such as being a noninvasive, safe diagnostic technique that correlates directly with the disease progression. Many tau tracers have been reported to date; however, the chemical scaffolds of them fall in a narrow chemical window, and none was approved yet as none is entirely selective and sensitive to tau. These problems are being solved as new tracers emerge constantly. In this report, the first-generation tau tracers such as [¹¹C]PBB3, 2-arylquinoline (THK) series, [¹⁸F]T808, and [¹⁸F]AV-1451 ([¹⁸F]T807) are reviewed from an organic and radiochemistry perspective; thus the most effective chemical approach to synthesize these tracers is discussed. This would help to design novel tracers which can meet the challenges faced by the current tracers.

• Journal of the Korean Institute of Rural Architecture
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• v.16 no.2
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• pp.27-34
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• 2014

This paper is to research the present condition of settlements in rural areas of the Integrated Cheongju city. Especially the study is focused on the 243 Ri of old Cheongwon-gun(county) from the geographical language. The numbers of settlement with geographical language collected in 243 Ri (10 Myun, 3 Eup, and 4 Gu) are 1,180. The geographical languages could be classified into 6 categories. The main results are as follows: The geographical languages of 243 Ri are classified and categorized in the order of nature(116 Ri, 68.31%), manmade(30 Ri, 12.34%), and location related(23 Ri, 9.46%). The geographical languages of nature are quite much in comparison with the others. The geographical languages of 1,180 settlements are classified and categorized in the order of nature(520units, 44.06%), location related(329 Units, 27.88%), and manmade(184 Units, 15.59%). The geographical languages of nature are much in comparison with the others, but are less than them of 243 Ri.

• Proceedings of the PSK Conference
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• 2003.10b
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• pp.243.1-243.1
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• 2003

The pharmacokinetics of eupatilin (an active components of Stillen, a new antigastritic agent) were investigated using UV-HPLC method. The quantitation limit of eupatilin was 10 ng/ml in plasma. After intravenous administration of eupatiln, 30 mg/kg to rats, the plasma concentrations of unchanged eupatilin declined rapidly with the mean terminal half-life of 0.101 hr. Total body clearance was 121 ml/min/kg, and fractions of dose excreted in urine and feces for 24 hr were only 2.5% and 0.919%, respectively. (omitted)