• Journal of the Korean Society of Radiology
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• v.85 no.3
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• pp.549-565
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• 2024

MRI is a crucial tool for diagnosing adenomyosis and identifying its related pathologies. To accurately diagnose adenomyosis, it is necessary to recognize both the typical MRI findings and atypical features of the condition. Recently, a standardized classification system has been developed to facilitate precise presurgical diagnosis of adenomyosis and to determine the appropriate treatment method. Differentiating between various subtypes based on MRI-based classification and identifying different MRI phenotypes can aid in categorizing patients with adenomyosis into specific treatment groups and monitoring their response to therapy.

• Journal of the Korean Society of Radiology
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• v.85 no.1
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• pp.222-229
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• 2024

Synchronous renal malignancies are seldom encountered or diagnosed post-renal resection. A combination of renal cell carcinoma (RCC) and urothelial carcinoma (UC) is most commonly reported. Typically, the RCC subtype is clear-cell RCC; however, a combination of collecting duct carcinoma (CDC) and UC has rarely been reported in the existing literature. Here, we present two cases of synchronous renal malignancy, specifically a combination of CDC and UC, in the ipsilateral kidney.

• Journal of The Korean Association For Science Education
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• v.27 no.2
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• pp.105-119
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• 2007

Several studies have attempted to test students' misconceptions of physics and to provide teaching strategies in order to repair them. The results from these studies have revealed that the diagnosis of students' misconception is crucial, although they often failed to grasp the practice of its implementation. In terms of being a type of methodology for science education, the Internet allows large-scale surveys and investigations to be carried out in a relatively short period of time. This paper reports the results of the development, implementation, and evaluation of a WEb-based SYStem for TEsting students' Misconceptions in physics (WEBSYSTEM) aimed at three groups (science educational researchers who study students' physics conceptions using the system as a detector, school science teachers who practice it as an instructional material, and students who benefit from it for their self-directed learning). The web-based testing system is based on a review of the instructional development strategies of ADDIE (Gustafson, Branch, 2002; Rha, Chung, 2001). Results showed that WEBSYSTEM could work effectively as a multi-purposed tool for the three target groups with a further partial revision, providing educational researchers with resourceful data to study students' misconceptions in physics. Issues of administrative strategies, reexamination of questionnaires, and international collaboration via WEBSYSTEM are discussed.

• IMMUNE NETWORK
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• v.21 no.1
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• pp.2.1-2.11
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• 2021

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection causes coronavirus disease 2019 (COVID-19), an ongoing pandemic disease. In the current review, we describe SARS-CoV-2-specific CD4⁺ and CD8⁺ T-cell responses in acute and convalescent COVID-19 patients. We also discuss the relationships between COVID-19 severity and SARS-CoV-2-specific T-cell responses and summarize recent reports regarding SARS-CoV-2-reactive T cells in SARS-CoV-2-unexposed individuals. These T cells may be cross-reactive cells primed by previous infection with human common-cold coronaviruses. Finally, we outline SARS-CoV-2-specific T-cell responses in the context of vaccination. A better understanding of SARS-CoV-2-specific T-cell responses is needed to develop effective vaccines and therapeutics.

• Proceedings of the Korean Statistical Society Conference
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• 2002.05a
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• pp.79-83
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• 2002

Since its introduction in 1995 by Schena et al. cDNA microarrays have been established as a potential tool for high-throughput analysis which allows the global monitoring of expression levels for thousands of genes simultaneously. One of the characteristics of the cDNA microarray data is that there is inherent noise even after the removal of systematic effects in the experiment. Therefore, replication is crucial to the microarray experiment. The assessment of reproducibility among replicates, however, has drawn little attention. Reproducibility may be assessed with several different endpoints along the process of data reduction of the microarray data. We define the reproducibility to be the degree with which replicate arrays duplicate each other. The aim of this note is to develop a novel measure of reproducibility among replicates in the cDNA microarray experiment based on the unprocessed data. Suppose we have p genes and n replicates in a microarray experiment. We first develop a measure of reproducibility between two replicates and generalize this concept for a measure of reproducibility of one replicate against the remaining n-1 replicates. We used the rank of the outcome variable and employed the concept of a measure of tracking in the blood pressure literature. We applied the reproducibility measure to two sets of microarray experiments in which one experiment was performed in a more homogeneous environment, resulting in validation of this novel method. The operational interpretation of this measure is clearer than Pearson's correlation coefficient which might be used as a crude measure of reproducibility of two replicates.

• Journal of Families and Better Life
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• v.25 no.5
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• pp.167-183
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• 2007

The purpose of this study was to investigate the changes in infant-mother interactions and to measure infant-mother interaction, mutuality, and reciprocity at the 2nd and 6th postnatal monthperiods. Infant-mother interaction was assessed in the mornings, afternoons, and evenings in the 2nd and 6th postnatal months, by filming unstructured free play in the home and analyzing 28 of these infant-mother film recordingsusing two trained observers. This study can be summarized in five points. First, the separate frequency distribution of each category in MIIBR's maternal behavior was as follows: the frequencies of vocalization category, the kinesthetic exercise & physical contact category, the physical caregiving category, and theuse of play tool category. These all showed changes in the 6th postnatal month compared to the 2nd postnatal month. Second, the separate frequency distribution of each category in MIIBR's infant behavior was as follows: the frequencies of physical behavior category, the vocalization category, and the play behavior category. These also all showed changes in the 6th postnatal month compared to the 2nd postnatal month. Third, the mutuality and reciprocity of mother interaction decreased in the 2nd postnatal month compared to the 6th postnatal month. Fourth, mutuality and reciprocity in the infant interaction increased in 2nd postnatal month compared to the 6th postnatal month. Fifth, mutuality and reciprocity in the infant-mother interaction increased in 2nd postnatal month compared to the 6th postnatal month. In conclusion, it is evident that infant-mother interactions change over time. This study bears particular significance in setting a foundation for the theoretical basis of the interaction between infant and mother by observation.

• Clinical and Experimental Reproductive Medicine
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• v.11 no.2
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• pp.17-25
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• 1984

Hypothalamic-pituitary function in patients of 6 selected groups of amenorrhea was evaluated by performing premarin test. Selected amenorrheic patients were divided into 6 groups of Turner's syndrome(5), adrenogenital syndrome(3), Sheehan's syndrome(4), moderate hyperprolactinemia(3), severe hyperprolactinemia(9) and functional oligoamenorrhea(9) the diagnoses of which were performed according to modified our own protocol for management of amenorrheic patients. As control 20 normally cycling women in mid follicular phase determined by their symptothermal charts during last 6 months designed by WHO were compared. The premarin test which is one of the tests evaluating the hypothalamic-pituitary function by the principle of negative and positive feed back effect's of estrogen was performed by injecting 20 mg of premarin in volus intravenously. The levels of serum LH before, 24, 48, 72, 96 and 120 hours after injection of premarin were measured by double antibody technique radioimmunoassay the reagents of which were supplied by WHO. The results were as follows: 1. Both negative and positive feed back effects by exogenous estrogen were well preserved even in the patients of gonadal dysgenesis although the baseline levels were much higher than normal. 2. In the patients of Sheehan's syndrome one could observe the minimal response of feed back effect in the case with minimal pituitary function. 3, Androgens in adrenogenital syndrome and prolactin in hyperprolactinemia may suppress mainly the positive feed back effect rather than the negative one. The suppressive effect can be abolished by proper treatments which can eliminate those suppressive hormones. 4. This premarin test may be beneficial for predicting the result of clomiphene in ovulation induction.

• Mycobiology
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• v.40 no.2
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• pp.124-128
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• 2012

Multiple treatment modalities, including topical and systemic corticosteroid and phototherapy, have been used in treatment of patients with atopic dermatitis. However, long-term corticosteroid therapy may have various adverse effects. The purpose of this study was to investigate the therapeutic efficacy and safety of bath therapy using green tea extracts for treatment of patients with atopic dermatitis. A total of four patients with atopic dermatitis were enrolled in this study. A Malassezia multiplex detection kit was used in performance of multiplex PCR on clinical isolates, which confirmed Malassezia sympodialis. Subjects underwent treatment with bath therapy using green tea extracts three times per wk for a period of 4 wk. Assessment using the scoring atopic dermatitis (SCORAD) index, the visual analogue scale for pruritus, and transepidermal water loss was performed weekly. Laboratory tests were performed before and after treatment. All patients showed marked improvement on the mean SCORAD and visual analogue scale, and a significant decrease in the mean values of serum eosinophil counts was observed after treatment. Bath therapy with green tea extract is an effective, safe, and nonsteroidal therapy for treatment of patients with atopic dermatitis associated with Malassezia sympodialis.

• Korean Journal of Plant Resources
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• v.25 no.6
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• pp.731-738
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• 2012

Dandelion has been widely utilized for medicinal and edible purposes. This research was conducted to evaluate the effect of supplemental LED (light-emitting diode) light on germination, growth characteristics and anthocyanin content of dandelion (Taraxacum officinale) seedling using LED blue (460 nm), red (660 nm, R), blue + red (B:R=6:4) and fluorescent lamp light treatment. By LED illumination to T. officinale seed germination speed was delayed, and germination rate was the highest in the fluorescent light. The growth characteristics (plant height, number of leaves, root length and fresh weight) were greatly influenced by supplemental LED light compared with control treatment, and the growth promotion was the most effective in the red LED illumination. After 60 days of red and mixed LED light treatments, anthocyanin content of dandelion plants was significantly changed. The anthocyanin content was increased by 12~19 mg/100 g under the red LED and the mixed light conditions compared with the control and the blue LED. Results indicate that illumination with red and mix LEDs, compared with other light treatments, is beneficial for promotion of growth and anthocyanin content in dandelion.

• Structural Engineering and Mechanics
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• v.32 no.3
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• pp.383-398
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• 2009

Applying nonlinear statistical analysis methods in estimating the performance of structures in earthquakes is strongly considered these days. This is due to the methods' simplicity, timely lower cost and reliable estimation in seismic responses in comparison with time-history nonlinear dynamic analysis. Among nonlinear methods, simplified to be incorporated in the future guidelines, Modal Pushover Analysis, known by the abbreviated name of MPA, simply models nonlinear behavior of structures; and presents a very proper estimation of nonlinear dynamic analysis using lateral load pattern appropriate to the mass. Mostly, two kinds of connecting joints, 'hinge' and 'rigid', are carried out in different type of steel structures. However, it should be highly considered that nominal hinge joints usually experience some percentages of fixity and nominal rigid connections do not employ totally rigid. Therefore, concerning the importance of these structures and the significant flexibility effect of connections on force distribution and elements deformation, these connections can be considered as semi-rigid with various percentages of fixity. Since it seems, the application and implementation of MPA method has not been studied on moment-resistant steel frames with semi rigid connections, this research focuses on this topic and issue. In this regard several rigid and semi-rigid steel bending frames with different percentages of fixity are selected. The structural design is performed based on weak beam and strong column. Followed by that, the MPA method is used as an approximated method and Nonlinear Response History Analysis (NL-RHA) as the exact one. Studying the performance of semi-rigid frames in height shows that MPA technique offers reasonably reliable results in these frames. The methods accuracy seems to decrease, when the number of stories increases and does decrease in correlation with the semi-rigidity percentages. This generally implies that the method can be used as a proper device in seismic estimation of different types of low and mid-rise buildings with semi-rigid connections.