• Journal of the Society of Cosmetic Scientists of Korea
• /
• v.36 no.2
• /
• pp.129-136
• /
• 2010

In order to evaluate anti-wrinkle activity of Carex humilis extract, free radical scavenging activity, elastase inhibitory activity and reduction of expression Matrix metalloproteinase-1 (MMP-1) mRNA and MMP-1 protein were investigated. The roots of Carex humilis were extracted with 95 % ethanol and successively partitioned with organic solvents with increasing polarity of the solvents. Each fraction of organic solvent were investigated by using free radical scavenging activity and elastase inhibitory activity test. Among them, EtOAc fraction showed antioxidant activity ($SC_{50}$=4.89 ${\mu}g/mL$) and elastase inhibitory activity ($IC_{50}$=23.5 ${\mu}g/mL$). EtOAc fraction was developed on silica gel by open-column chromatography and consecutively re-developed on C18 resin by prep-HPLC to give ${\alpha}$-viniferin as a major component, which was confirmed by spectrometric analysis. In the assay on expression of MMP-1 mRNA by RT-PCR and protein by western-blot, EtOAc layer (10 ~ 100 ${\mu}g/mL$) was reduced about 50 ~ 60 %, 50 ~ 65 % respectively and ${\alpha}$-viniferin (0.5 ~ 2 ${\mu}g/mL$) was inhibited about 60 ~ 75 %, 55 ~ 65 % respectively in human fibroblast. Therefore, our findings suggest that EtOAc layer of Carex humilis containing ${\alpha}$-viniferin can be useful as an active ingredient for cosmeceuticals of anti-wrinkle effects.

• Journal of the Korean Solar Energy Society
• /
• v.28 no.2
• /
• pp.64-69
• /
• 2008

As the grid-connected photovoltaic power conditioning systems (PVPCS) are installed in many residential areas, these have raised potential problems of network protection on electrical power system. One of the numerous problems is an Islanding phenomenon. There has been an argument that it may be a non-issue in practice because the probability of islanding is extremely low. However, there are three counter-arguments: First, the low probability of islanding is based on the assumption of 100% power matching between the PVPCS and the islanded local loads. In fact, an islanding can be easily formed even without 100% power matching (the power mismatch could be up to 30% if only traditional protections are used, e.g. under/over voltage/frequency). The 30% power-mismatch condition will drastically increase the islanding probability. Second, even with a larger power mismatch, the time for voltage or frequency to deviate sufficiently to cause a trip, plus the time required to execute a trip (particularly if conventional switchgear is required to operate), can easily be greater than the typical re-close time on the distribution circuit. Third, the low-probability argument is based on the study of PVPCS. Especially, if the output power of PVPCS equals to power consumption of local loads, it is very difficult for the PVPCS to sustain the voltage and frequency in an islanding. Unintentional islanding of PVPCS may result in power-quality issues, interference to grid-protection devices, equipment damage, and even personnel safety hazards. Therefore the verification of anti-islanding performance is strongly needed. In this paper, improved RPV method is proposed through considering power quality and anti-islanding capacity of grid-connected single-phase PVPCS in IEEE Std 1547 ("Standard for Interconnecting Distributed Resources to Electric Power Systems"). And the simulation results are verified.

• Land and Housing Review
• /
• v.2 no.4
• /
• pp.397-406
• /
• 2011

This research aims to develop various infill-systems for practically applying to long-life housing with 100-year durability and flexibility as a strategy for realizing sustainable residential environment. Especially, the developed infill-systems & technologies were concentrated to the mock-up house applied with the standard model of long-life housing, and their in-situ applicability by a phase, experts' consultation, and questionnaire survey were also evaluated. This research was executed to divide by 3 phases. In the First phase infill-systems for a housing unit of $84m^2$ exclusive use area as well as a support of whole structure and infill-systems including dry wall, and windows were constructed, and their in-situ applicability were evaluated. In the Second phase vertical integration of upper and lower housing units of $50m^2$ and $40m^2$ exclusive use area was investigated the first in domestic for 3 housing units of $50m^2$ exclusive use area. In addition, various infill-systems including the horizontal expansion of $50m^2$ and $10m^2$ exclusive use areas were also constructed and evaluated on their in-situ applicability. In the third phase diverse performance tests and field investigation for in-situ verifying of dry Ondol, developed this research, were executed to improve their practicability. Inner dry walls were taken apart, moved and re-constructed for verifying their practicability to investigate 3R-Reduce, Reuse and Recycle-realization too.

• (The)Study of the Eastern Classic
• /
• no.59
• /
• pp.297-324
• /
• 2015

This article discusses Dasan Cheong Yagyong(1762-1836)'s perspectives on The Book of historical documents("書經"). Dasan Cheong Yagyong considered The Shoo King as The Book of historical documents presented Ideas of Confucian Politics in ancient China. Many Scholar and Kings dispersed and re-edition The Shoo King as historical documents. Dasan Cheong Yagyong analyzed, de-constructed, and reinterpretations documents of dominant The Shoo King. Dasan Cheong Yagyong tried to recover the original documents The Shoo King. Dasan Cheong Yagyong collected dispersed material of The Shoo King, and complied the original documents. Dasan Cheong Yagyong wrote four book of The Shoo King. Dasan want to reconstruct the new theory by these reinterpretations of The Book of historical documents presented Ideas of Confucian Politics in ancient China, and to open new era.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
• /
• v.28 no.3
• /
• pp.30-47
• /
• 2015

Objective : Melanoma is a very critical and devastating disease. Although many people have depended on surgical operation in melanoma treatment, they have placed importance on non-invasive methods constantly. So we planned to establish a research methodology by analysing existing articles containing conservative melanoma treatments in Journals of Korean Medicine published in Korea.Methods : Using search words of anti-cancer, B16, cancer, lung metastasis, melanoma, metastasis, S-100, SK-MEL, tumor, tyrosinase, we collected 26 articles by searching internet portal sites as following;Using search words of anti-cancer, B16, cancer, lung metastasis, melanoma, metastasis, S-100, SK-MEL, tumor, tyrosinase, we collected 26 articles by searching internet portal sites as followinghttp://oasis.kiom.re.kr,http://www.koreantk.com,http://www.riss.kr,http://www.dbpia.co.kr,http://www.ndsl.kr,http://kiss.kstudy.com,http://www.naver.com,http://www.google.com.Result : The number of articles is 26 and in the year of 2003, 2004 is ranked the highest number in publication. The journal of acupuncture & moxibustion society ranked the highest(30.8%). 2 and 4 authors ranked the highest(26.9%) in number of authors. T-test ranked the highest(58.1%) in statistics methods. P.O. med indicated in 11 articles and Pharmacopuncture in 15 articles. B16 murine melanoma cell was indicated in 25 articles by cancer-induced methods. In measurement, T cell activity was indicated in 14 articles, NK activity in 4 articles, IL-2 in 6 articles, apoptosis in 1 article, lung metastasis in 14 articles.Conclusion : Considering overall results, it is necessary to diversify cancer-induced methods and measurement methods in experimental melanoma research.

• Resources Recycling
• /
• v.30 no.6
• /
• pp.61-67
• /
• 2021

This work investigated the cementation of iridium from iridium-containing hydrochloric acid leachate. Zinc powder was used as the reducing agent, and the effects of the stoichiometric ratio of Zn/Ir, initial Ir concentration, initial pH, reaction time, and ultrasound irradiation on iridium recovery were investigated. When only the stirrer was used for cementation, the iridium recovery increased with the addition amount of zinc, and the recovery of about 70% at 40 times the stoichiometric ratio of Zn/Ir. In contrast, when employing ultrasonic irradiation with stirring, the recovery of iridium decreased at 20 times or less the stoichiometric amount of zinc. The recovery of iridium increased at 40 times the stoichiometric ratio of Zn/Ir. This result may be due to the ionization of zinc and re-dissolution of iridium during the ultrasound irradiation treatment. When a combination of ultrasonic irradiation and stirring was used for cementation, the iridium recovery increased by more than 27% compared to that when using only the stirrer. It was possible to recover 99% of iridium under the following conditions: reaction time, 60 min; initial pH, 0.01; volume of leachate, 100 mL; 1770 ppm Ir, 40 times the stoichiometric ratio of Zn/Ir.

• Korean Journal of Applied Biomechanics
• /
• v.31 no.4
• /
• pp.241-248
• /
• 2021

Objective: The purpose of this study was to investigate the difference in muscle strength, kinematics, and kinetics between injured and non-injured sides of the leg after Achilles Tendon Rupture surgery during walking and running. Method: The subjects (n=11; age = 30.63 ± 5.69 yrs; height = 172.00 ± 4.47 cm; mass = 77.00 ± 11.34 kg; time lapse from surgery = 29.81 ± 10.27 months) who experienced Achilles Tendon Rupture (ATR) surgery participated in this study. The walking and running trials were collected using infrared cameras (Oqus 300, Qualisys, Sweden, 100 Hz) on instrumented treadmill (Bertec, U.S.A., 1,000 Hz) and analyzed by using QTM (Qualisys Track Manager Ver. 2.15; Qualisys, U.S.A). The measured data were processed using Visual 3D (C-motion Inc., U.S.A.). The cutoff frequencies were set as 6 Hz and 12 Hz for walking and running kinematics respectively, while 100 Hz was used for force plate data. Results: In ATR group, muscle strength there were no difference between affected and unaffected sides (p> .05). In kinematic analysis, subjects showed greater ROM of knee joint flexion-extension in affected side compared to that of unaffected side during walking while smaller ROM of ankle dorsi-plantar and peak knee flexion were observed during running (p< .05). In kinetic analysis, subjects showed lower knee extension moment (running at 2.2 m/s) and positive ankle plantar-flexion power (running at 2.2 m/s, 3.3 m/s) in affected side compared to that of unaffected side (p< .05). This lower positive ankle joint power during a propulsive phase of running is related to slower ankle joint velocity in affected side of the subjects (p< .05). Conclusion: This study aimed to investigate the functional evaluation of the individuals after Achilles tendon rupture surgery through biomechanical analysis during walking and running trials. Based on the findings, greater reduction in dynamic joint function (i.e. lower positive ankle joint power) was found in the affected side of the leg compared to the unaffected side during running while there were no meaningful differences in ankle muscle strength and walking biomechanics. Therefore, before returning to daily life and sports activities, biomechanical analysis using more dynamic movements such as running and jumping trials followed by current clinical evaluations would be helpful in preventing Achilles tendon re-rupture or secondary injury.

• Journal of the Korean Society of Marine Environment & Safety
• /
• v.23 no.7
• /
• pp.767-774
• /
• 2017

Maritime traffic safety audits (MTSA) were enacted in order to ensure marine traffic safety throughout changes or the construction of water facilities, port facilities, etc. After the introduction of MTSA, the scope of subject vessels was restricted to an LOA of more than 100 m or a maximum speed of more than 60 knots as of 2014. In this study, the scope of subject vessels was re-examined in comparison with specific marine traffic safety areas and tanker prohibited areas identified in the maritime safety act. Furthermore, the state of subject vessels and exception cases for MTSA were also analyzed. As a result of these analyses, MTSA were deemed necessary for dangerous goods carriers of more than 1,000 G/T in specific marine traffic safety areas and dangerous goods carriers of more than 794 G/T in tanker prohibited areas. Finally, the necessity of further review was suggested given the present scope of subject vessels.

• Korean Journal of Veterinary Service
• /
• v.44 no.2
• /
• pp.73-83
• /
• 2021

Although many swine farms continuously vaccinated to sow to prevent Porcine epidemic diarrhea(PED), PED has occurred annually in swine herds in Jeonbuk province, Korea. In the present study, the small intestine and feces samples from 17 farms where severe watery diarrhea and death of newborn piglets occurred in 2019 were collected, amplified by RT-PCR and determined the complete nucleotide sequences of the spike (S) glycoprotein genes of nine Jeonbuk PEDV isolates. The spike (S) glycoprotein is an important determinant for molecular characterization and genetic relationship of PEDV. These nine complete S gene isolates were compared with other PEDV reference strains to identify the molecular diversity, phylogenetic relationships and antigenicity analysis. 9 field strains share 98.5~100% homologies with each other at the nucleotide sequence level and 97.3~100% homologies with each other at the amino acid level. The nine Jeonbuk PEDV isolates were classified into G2b group including a genetic specific signal, S-indels (insertion and deletion of S gene). In addition, comparisons the neutralizing epitopes of S gene between 9 field strains and domestic vaccine strains of Korea mutated 12-15 amino acids with SM-98-1 (G1a group) and mutated 0-3 amino acids with QIAP1401 (G2b group). Therefore, the development of G2b-based live vaccines will have to be expedited to ensure effective prevention of endemic PED in Korea. In addition, we will need to be prepared with periodic updates of preventive vaccines based on the PEDV variants for the re-emergence of a virulent strain.

• Journal of the Korean Society of Radiology
• /
• v.16 no.3
• /
• pp.217-223
• /
• 2022

In this study, images taken using a grid and images taken using Air Gap Technique were evaluated in X-ray chest radiography. Subjective Evaluation The ROC (Receiver Operating Characteristic) evaluation was evaluated by 5 radiologists who had worked for more than 10 years in the radiology department of a university hospital. Objective evaluation SNR (Signal to noise ratio) was evaluated. As a result of the analysis, the Cronbach Alpha value was 0.714, which was significantly higher. In the Air Gap Technique, the distance between the phantom and the subject was set at 20 cm, and the image was taken with a tube voltage of 100 kVp, a tube current and a recording time of 8 mAs. In the ROC (Receiver Operating Characteristic) evaluation, the highest score was obtained with 18 score and an objective evaluation SNR (signal to noise ratio) of 6,149 scored. Also, in the imaging method using a grid, when the distance between the phantom and the constant receptor is 15 cm apart, and the tube voltage is 110 kVp, the tube current and the recording time are taken at 8 mAs, the ROC evaluation score is 19 and the objective evaluation SNR (Signal to noise ratio) is the highest with 6.622 scored. Therefore, if the Air Gap Technique imaging method is used, which overcomes the shortcomings such as delay in reading, increase in patient's exposure dose, and shortening of mechanical lifespan, as well as re-radiography due to the cut-off phenomenon of the grid that appears using the grid, the It is thought that it will be very helpful for chest imaging, including the case of using a portable X-ray imaging device.