• 제목/요약/키워드: RD-14 Test

검색결과 125건 처리시간 0.035초

중수로 실증 실험설비를 이용한 소형냉각재상실사고의 MARS-KS 입력모델 개발 및 검증계산 (Development and Validation of MARS-KS Input Model for SBLOCA Using PHWR Test Facility)

  • 백경록;유선오
    • 한국안전학회지
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    • 제36권2호
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    • pp.111-119
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    • 2021
  • Multi-dimensional analysis of reactor safety-KINS standard (MARS-KS) is a thermal-hydraulic code to simulate multiple design basis accidents in reactors. The code has been essential to assess nuclear safety, but has mainly focused on light water reactors, which are in the majority in South Korea. Few previous studies considered pressurized heavy water reactor (PHWR) applications. To verify the code applicability for PHWRs, it is necessary to develop MARS-KS input decks under various transient conditions. This study proposes an input model to simulate small-break loss of coolant accidents for PHWRs. The input model includes major equipment and experimental conditions for test B9802. Calculation results for selected variables during steady-state closely follow test data within ±4%. We adopted the Henry-Fauske model to simulate break flow, with coefficients having similar trends to integrated break mass and trip time for the power supply. Transient calculation results for major thermal-hydraulic factors showed good agreement with experimental data, but further study is required to analyze heat transfer and void condensation inside steam generator u-tubes.

형방지황탕이 Alzheimer's disease 모델 백서의 학습과 기억에 미치는 영향 (The effects of Hyungbangjiwhangtang on Learning and Morris water maze and Radial arm maze paradigm)

  • 조윤숙;황의완;김현택;박순권
    • 동의신경정신과학회지
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    • 제9궈1호
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    • pp.1-24
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    • 1998
  • The effects of Hyungbangjiwhangrang on the enhancement of learning and memory of AD model rats were studied with Morris water maze and radial arm maze. Sample group was electrolytically lesioned on nbM, and then daily treated with the medicine for two months. Control group with nbM lesion, and sham group with the sham operation were treated the vehicle for same duration. The following results were observed.1. As the learning trials of Morris water maze processed repeatedly, sham group achiened 201.64${\pm}$33.13 seconds in 1st trial, 153.14${\pm}$61.80 seconds in 2nd, 106.21${\pm}$46.81 seconds in 3rd, 76.64${\pm}$48.40 seconds in 4th, and 52.29${\pm}$38.25 seconds in 5th. The control group achieved 224.08${\pm}$29.16 in 1st trial, 191.77${\pm}$67.97 seconds in 2nd, 177.77${\pm}$65.44 seconds in 3rd, 140.92${\pm}$68.27 seconds in 4th, and 126.46${\pm}$79.15 seconds in 5th. The sample group achieved 223.36${\pm}$23.33 seconds in 1st trial, 215.86${\pm}$38.93 seconds in 2nd, 190.79${\pm}$51.57 seconds in 3rd, 155.79${\pm}$62.67 seconds in 4th, and 127.93${\pm}$62.11 seconds in 5th. Therefore, these data shows that all three groups were improved in learning capacity as trials were repeated, but the shame group showed prominent improvement in learning compared with the control group(p<0.05).2. In memory retention test of Morris water maze that counts the staying time in the target area, sham group stayed for 15.36${\pm}$5.39 seconds, the control group stayed for 5.54${\pm}$5.64 seconds, and the sample group stayed for 7.43${\pm}$6.09 seconds. The analysis of the memory retention data shows that the sham group marked more significant improvement stati- stically in memory retention compared with the control group(p<0.05).3. In the learning of radial arm maze, the number and rate of animals that arrive the learning criteria amounted 12 out of 14, 85.7% in sham group, 4 out of 13, 30.8% in the control group, and 10 out of 14, 71.4% in the sample group So, the sample group shows better learning capacity significantly compared with the control group(p<0.05). With the experimental results above, Hyungbangjiwhangtang can be supposed to have the improving effects on the learning and memory of AD rats induced by eletronical injury of nbM.

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초고속 클라우드 비디오 서비스 실현을 위한 SDN 기반의 다중 무선접속 기술 제어에 관한 연구 (A Study of Development for High-speed Cloud Video Service using SDN based Multi Radio Access Technology Control Methods)

  • 김동하;이성원
    • 방송공학회논문지
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    • 제19권1호
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    • pp.14-23
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    • 2014
  • 본 논문은 최근 이동통신 네트워크에서 폭발적으로 증가하고 있는 비디오 트래픽이 야기한 문제와 요구사항의 해결책으로써, SDN(Software Defined Network)을 기반으로 하는 다중 무선 접속 기술(Multiple Radio Access Technology)의 제어 기법을 제안하고 그 성능을 자체 구축한 테스트베드를 통하여 평가한다. 이를 위하여, 먼저 사업자 입장에서 3rd-party의 비디오 트래픽을 사업자망으로부터 우회(off-loading)시키는 방안의 필요성과, 사용자에게 저비용으로 고속의 대용량 비디오 콘텐츠 서비스를 제공하는 방안에 대하여 논의한다. 또한 성능평가를 위한 테스트베드는 OpenStack 클라우드 및 SDN 기반으로 구축 하였다. 이를 통해, OpenFlow와 Open Switch를 이용하여 2개의 2.4GHz 무선 랜 링크와 3개의 5GHz 무선 랜 링크가 동시에 하나의 서비스를 지원하도록 함으로서 820 Mbps 급의 초고속 클라우드 비디오 서비스를 위한 전송 속도를 실현하였다.

양혈장근건보탕(養血壯筋健步湯)과 녹용약침(鹿茸藥鍼)이 척수손상 유발 흰쥐의 운동기능 회복 및 신경재생에 미치는 영향 (Effects of Yanghyuljanggeungunbo-tang(Yangxuezhuangjinjianbu-tang) and Cervi Cornu Parvum Pharmaco-Acupuncture on the Motor Function Recovery and Nerve Regeneration in Rats Induced Spinal Cord Injury)

  • 박지용;설재욱;김선종;최진봉;신미숙
    • 한방재활의학과학회지
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    • 제19권2호
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    • pp.27-49
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    • 2009
  • Objectives : The purpose of this study was to investigate the effects of Yanghyuljanggeungunbo-tang(Yangxuezhuangjinjianbu-tang) and Cervi Cornu Parvum pharmaco-acupuncture in Spinal Cord Injury(SCI)-induced rats. Methods : The subjects were divided into 5 groups ; Normal, Control no treatment after SCI, Experimental I taken with Yanghyuljanggeungunbo-tang (Yangxuezhuangjinjianbu-tang) 500 mg/kg $0.5m{\ell}$ daily after inducing SCI. Experimental II taken with Cervi Cornu Parvum pharmaco-acupuncture at Taegye(KI3) and $Yangnungch{\acute{o}}n$(GB34) after inducing SCI and Experimental III taken with Yanghyuljanggeungunbo-tang(Yangxuezhuangjinjianbu-tang) 500 mg/kg $0.5m{\ell}$ and Cervi Cornu Parvum pharmaco-acupuncture at KI3 and GB34 to SCI-induced rats. After each operation, the present author observed the motor behavior recovery and nerve regeneration by analysis of the motor behavior tests, EMG, hematological(AST, ALT, WBC), histological and immunological changes. Rats were tested at modified Tarlov test at the 1st, 2nd, 3rd, 4th day, and Motor behavior test at 1st, 3rd, 7th, 14th, 21st day. Results : Results are as follows. 1. All the experimental groups were improved compared with control group in the motor behavior tests including Tarlov test, Basso-Beattle-Bresnahan locomotor rating scale, modified inclined plane test, open field test, grid walk test and narrow beam test. Especially Experimental III was improved significantly among other groups. 2. In EMG test, H wave appeared weak only in Experimental III. And M wave was increased significantly in Experimental III. 3. All the experimental groups were significantly decreased compared with control group in serum AST, serum ALT and serum WBC tests. 4. significantly decreased in Tumor Necrosis Factor-${\alpha}$ test compared with the first day of SCI. 5. Muscle contraction and denaturation of all the experimental groups were inhibited in histological observations of gastrocnemius muscle. Especially, those of experimental III was more effective. 6. NGF and BDNF of spinal cord gray matter in all the experimental groups were increased compared with control group. Especially, those of experimental III was more effective. Conclusions : As above, it can be suggested that Yanghyuljanggeungunbo-tang(Yangxuezhuangjinjianbu-tang) and Cervi Cornu Parvum pharmaco-acupuncture may improve motor behavior, EMG, hematological, histological and immunological findings in Spinal Cord Injury(SCI)-induced rats. Especially, effects will be somewhat better in combination of these two treatments.

척수손상 흰쥐에서 수영훈련이 운동기능 회복에 미치는 영향 (The Effect of the Swimming Exercise on Motor Functional Recovery after Experimental Contusive Spinal Cord Injury in the Rats)

  • 김용억;김경윤
    • The Journal of Korean Physical Therapy
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    • 제19권3호
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    • pp.1-9
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    • 2007
  • Purpose: Previous studies have suggested that BDNF has a role in plasticity and survival following spinal cord injury and treadmill exercise increases BDNF levels in the normal brain and spinal cord. We attempted to determine whether swimming exercise improve motor function following experimental contusive spinal cord injury and whether motor outcome is associated with BDNF expression. Methods: Thirty six Sprague-Dawley rats (weight, 250 to 300 g) were divided into control (n=18) and experimental swimming group (n=18). Spinal cord injury was produced using NYU-spinal impactor at the eleven thoracic levels in both groups. Swimming exercise started $7^{th}$ day from SCI operation, lasted 5 min per day, 5 days a week for 4 weeks and then exercise times a day were increased in one number to each week. Motor functional recovery was determined by the Basso-Beattie-Bresnahan (BBB) locomotor rating scale, modified inclined board plane test, histological findings, H&E and BDNF expression observed at $1^{th}$, $3^{rd}$, $7^{th}$, $14^{th}$, $21^{st}$ and $28^{th}$day after injury. Results: 1. The BBB scores were higher in experimental group than control group at $14^{th}$, $21^{st}$ day (left hind limb) and at $21^{th}$ day (right hind limb) (p<0.05) after injury. 2. The inclined board plane test were significantly greater in experimental group than control group at $7^{th}$ day (p<0.05), $14^{th}$ and $28^{th}$ day (p<0.01) after injury. 3. The BDNF expression was severe revealed in experimental group than control group at $7^{th}$, $14^{th}$ and $28^{th}$ day after injury. Conclusion: This study suggests that swimming applied from the early phase after spinal cord injury be beneficial effects in motor functional recovery.

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Characterization of Paenibacillus sp. MBT213 Isolated from Raw Milk and Its Ability to Convert Ginsenoside Rb1 into Ginsenoside Rd from Panax ginseng

  • Renchinkhand, Gereltuya;Cho, Soo Hyun;Urgamal, Magsar;Park, Young W;Nam, Joong Hyeon;Bae, Hyung Churl;Song, Gyu Yong;Nam, Myoung Soo
    • 한국축산식품학회지
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    • 제37권5호
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    • pp.735-742
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    • 2017
  • This study was conducted to isolate and characterize Paenibacillus sp. MBT213 possessing ${\beta}$-glucosidase activity from raw milk, and examine the enzymatic capacity on the hydrolysis of a major ginsenoside ($Rb_1$). Strain MBT213 was found to have a high hydrolytic ability on ginsenoside $Rb_1$ by Esculin Iron Agar test. 16S rDNA analysis revealed that MBT213 was Paenibacillu sp. Crude enzyme of MBT213 strain exhibited high conversion capacity on ginsenoside $Rb_1$ into ginsenoside Rd proven by TLC and HPLC analyses. The API ZYM kit confirmed that Paenibacillu sp. MBT213 exerted higher ${\beta}$-glucosidase and ${\beta}$-galactosidase activity than other strains. Optimum pH and temperature for crude enzyme were found at 7.0 and $35^{\circ}C$ in hydrolysis of ginsenoside $Rb_1$. After 10 d of optimal reaction conditions for the crude enzyme, ginsenoside $Rb_1$ fully converted to ginsenoside Rd. Ginseng roots (20%) were fermented for 14 d, and analyzed by HPLC showed that amount of ginsenoside $Rb_1$ significantly decreased, while that of ginsenoside Rd was significantly increased. The study confirmed that the ${\beta}$-glucosidase produced by Paenibacillus sp. MBT213 can hydrolyze the major ginsenoside $Rb_1$ and convert to Rd during fermentation of the ginseng. The ${\beta}$-glucosidase activity of this novel Paenibacillus sp. MBT213 strain may be utilized in development of variety of health foods, dairy foods and pharmaceutical products.

대학생의 불안, 취업스트레스 및 자아존중감이 우울에 미치는 영향 -회복탄력성의 조절효과- (Influence on College Students' Depression of Anxiety, Unemployment Stress, and Self-esteem - Moderating Effect of Resilience -)

  • 최승혜;이해영
    • 한국콘텐츠학회논문지
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    • 제14권10호
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    • pp.619-627
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    • 2014
  • 본 연구는 대학생의 우울 정도를 파악하고, 불안, 취업스트레스, 자아존중감과 우울의 상관관계 및 이들의 관계에 회복탄력성이 미치는 조절효과를 규명하기 위한 서술적 조사연구이다. 본 연구는 S대학에 재학중인 대학생 298명을 대상으로 하였다. 수집된 자료는 t-test, ANOVA test, Pearson correlation coefficient, 조절회귀분석을 이용하여 분석하였다. 연구결과 남학생보다 여학생의 우울점수가 높고, 3학년보다는 1,2,4학년의 우울정도가 높았으며, 가족 경제수준에 따라 우울정도의 유의한 차이가 있었다. 또한, 우울은 불안, 취업스트레스와 양의 상관관계가 있었고, 자아존중감, 회복탄력성과 음의 상관관계가 있는 것으로 나타났다. 우울에 영향을 주는 조절요인에 대한 분석결과 회복탄력성 중 자기조절능력이 자아존중감과 불안을 조절하는 효과가 있는 것으로 나타났다. 이상의 결과를 바탕으로 대학생의 우울을 조절하기 위해서는 불안과 취업스트레스를 낮추고 자아존중감을 높이는 것이 중요하며, 이를 위해서는 회복탄력성 중 특히 자기조절능력을 향상시키는 전략이 효과적일 것으로 생각된다.

광주지역 고등학교 3학년생의 비정시안의 굴절상태에 대한 고찰 (Relationship on the Refractive Status of the High School 3rd Grade Students with Subnormal Visual Acuity in Gwangju Metropolitan City)

  • 윤영;유근창
    • 한국안광학회지
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    • 제12권3호
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    • pp.105-110
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    • 2007
  • 본 연구는 광주지역 고등학교 3학년생 111명 222안을 대상으로 굴절상태를 자각적, 타각적 검안을 토대로 조사, 시행하여 안질환이 없는 학생의 비정시의 정도 및 굴절상태를 연구하였다. 눈의 형태는 근시가 85% 원시가 1% 그리고 정시가 14%로 나타났다. 굴절 이상안은 단순근시 38%, 근시성 단난시 4%, 근시성 복난시 56%, 단순원시 0%, 원시성 단난시 0%, 원시성 복난시 2%, 혼합난시 0% 순이었다. 난시의 축은 직난시 92%, 도난시 6%, 사난시 2%순이었다. 난시의 굴절력은 0.5D에서 1.0D가 68%, 1.0D에서 2.0D가 25%, 2.0D 이상이 7% 이었다. 근시성 굴절 이상안의 등가구면 굴절력은 -0.50D에서 -2.0D 이하 26%, -2.0D에서 -6.0D 이하에서 55%, -6.0D 이상이 19% 이었다. 안경 착용률은 74%로 20년 전에 비해 증가함을 알 수 있었다. 검안은 안경원에서 91%, 안과에서 9% 이었다. 최근 시력검사가 5개월이 넘은 학생 중에 안경렌즈 교체가 필요한 등가구면 굴절력이 0.5D가 넘은 경우는 80% 이었다.

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저속 압축성 유동에서 예조건화 방법을 이용한 수렴성 증진에 대한 연구 (A Study of Convergence Enhancement Using Preconditioning Methods at Two Dimensional Compressible Low Speed Flows)

  • 이재은;박수형;권장혁
    • 한국전산유체공학회:학술대회논문집
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    • 한국전산유체공학회 2004년도 추계 학술대회논문집
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    • pp.7-14
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    • 2004
  • It is well known that preconditioning methods are efficient for convergence acceleration at compressible low Mach number flows. In this study, the original Euler equations and three preconditioners nondimensionalized differently are implemented in two dimensional inviscid bump flows using the 3rd order MUSCL and DADI schemes as flux discretization and time integration respectively. The multigrid and local time stepping methods are also used to accelerate the convergence. The test case indicates that a properly modified local preconditioning technique involving concepts of a global preconditioning one produces Mach number independent convergence. Besides, an asymptotic analysis for properties of preconditioning methods is added.

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융복합기반 핵심기본간호술 재교육이 간호학생의 수행능력 및 자신감에 미치는 효과 (The Effects of Convergence-Based Reeducation on Core Basic Nursing Skills on Nursing Students' Competence and Confidence)

  • 정명숙;권영숙
    • 디지털융복합연구
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    • 제13권4호
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    • pp.295-302
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    • 2015
  • 본 연구는 융복합기반 핵심기본간호술 (피하주사 및 유치도뇨) 재교육이 간호학생의 수행능력, 지식, 태도 및 자신감에 미치는 효과를 파악하고자 시도되었다. 대상자는 일개 대학교의 간호학과 3학년 34명이었다. 실험처치 및 자료 수집은 2013년 12월 14일부터 12월 29일까지 시행되었다. 재교육 전과 후에 간이혈당 검사를 포함한 피하주사 및 유치도뇨술 및 구조화된 설문지를 이용한 지식, 태도, 자신감을 평가하였다. 수집된 자료는 SPSS 21 프로그램의 빈도분석, 기술통계 및 paired t-test를 이용하여 분석하였다. 연구 결과, 재교육 전에 비해 재교육 후의 피하주사 및 유치도뇨 수행능력(p<.001)은 유의하게 증가한 것으로 나타났다. 지식(p<.001), 피하주사 및 유치도뇨 수행 자신감(p<.001)도 재교육 후 유의한 증가를 보여 융복합기반 재교육 프로그램이 졸업 전 간호학생의 핵심기본간호술 역량을 높이는데 효과적임을 확인하였다. 그러므로 지속적으로 프로그램을 개발하고 후속 연구를 통하여 그 효과를 평가할 필요가 있다.