• Title/Summary/Keyword: RCT(randomized controlled trials)

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Chuna Manual Therapy for Rheumatoid Arthritis : A Systematic Review and Meta-analysis (류마티스 관절염에 대한 추나요법의 효과 : 체계적 문헌고찰과 메타분석)

  • Heo, In;Han, In-Sik;Cha, Yun-Yeop
    • The Journal of Churna Manual Medicine for Spine and Nerves
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    • v.13 no.1
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    • pp.1-10
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    • 2018
  • Objectives: To evaluate the evidence supporting the effectiveness of Chuna manual therapy for rheumatoid arthritis. Methods: We conducted a search across 9 electronic databases to find all randomized controlled clinical trials (RCTs) that used Chuna manual therapy as a treatment for rheumatoid arthritis. The methodological quality of each RCT was assessed using the Cochrane risk of bias tool. Results: Our inclusion criteria were met by 5 RCTs. The meta-analysis showed positive results for the use of Chuna manual therapy combined with oriental usual care (UC) in terms of the efficacy rate, pain, and duration of morning stiffness when compared to western UC. Positive results were also obtained in terms of the efficacy rate, when Chuna manual therapy combined with medication was compared to medication treatments alone. Conclusions: Our systematic review found encouraging, but limited evidence of Chuna manual therapy for rheumatoid arthritis. However, to obtain stronger evidence without the drawbacks of trial design and the quality of studies, we recommend a comparative research to test the effectiveness of Chuna manual therapy.

Tai-chi for Low back pain: Systematic Review (태극권 운동이 요통에 미치는 영향 : 체계적 문헌 고찰)

  • Choo, Su-Cheol;Kim, Kyu-Jin;Kim, Eun-Bi;Hwang, Eui-Hyoung
    • The Journal of Churna Manual Medicine for Spine and Nerves
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    • v.13 no.1
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    • pp.35-44
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    • 2018
  • Objectives: To determine the effectiveness of Tai-chi in treatinglow back pain. Methods: We searched 9 electronic databases(Pubmed, CAJ, EMBASE, Cochrane Library, Web of Science, KISS, KISTI, NDSL, and RISS) till April 2018 and included randomized controlled trials(RCTs) that used Tai-chi for lower back pain treatment. The methodological quality of each RCT was assessed usingthe Cochrane risk of bias tool. Results: As per the inclusion criteria, 5 RCTswere found to be eligible for our review. These studies were divided into 4 groups and meta-analysis was performed. The meta-analysis of 1 study showed favorable results regardingthe use of Tai-chi. Twostudies showed favorable results regardingthe use of Tai-chi with Tuina rather than Tuina alone. All studies were observed to have a high risk of bias. Conclusions: There is limited evidence available to support the effectiveness of Tai-chi in relieving low back pain;hence, additionalwell-designed RCTs should be encouraged for better evidence.

The Efficacy of Acupuncture on Postpartum Urinary Incontinence: A Systemic Review and Meta-analysis (산후 요실금에 대한 침의 효과 : 체계적 문헌고찰 및 메타분석)

  • Lee, Soo-Hyung;Kim, Song-Baek
    • The Journal of Korean Obstetrics and Gynecology
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    • v.35 no.3
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    • pp.37-55
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    • 2022
  • Objectives: The purpose of this study is to investigate the efficacy and safety of acupuncture on postpartum urinary incontinence. Methods: 'postpartum urinary incontinence', 'postnatal urinary incontinence', 'acupuncture' were searched on 4 online databases (Cochrane Library, Pubmed, CNKI, OASIS). Randomized controlled trials (RCTs) that used acupuncture on postpartum urinary incontinence were included. The methodological quality of each RCT was assessed by using Cochrane risk of bias tool. Results: 12 RCTs were finally selected. The overall risk of bias was evaluated as uncertain. 11 studies showed that combined treatment group was better than control group in effective rate and/or ICIQ-SF total score, but among those 1 study was not statistically significant in ICIQ-SF total score. In the comparison of alone treatment group and control group, 1 study showed favorable effect in ICIQ-SF total score, but 1 study was not significant in effective rate. Conclusions: Treatment that include acupuncture can effect on postpartum urinary incontinence. but considering quality of studies, inconsistent and insufficient evidence, further well-designed studies are needed to confirm the efficacy and safety of this treatment.

Efficacy of Muscle Energy Technique for Temporomandibular Disorders: A Systematic Review and Meta-analysis (턱관절 장애에 대한 근에너지 기법의 효과: 체계적 문헌 고찰 및 메타분석)

  • HongRyoul Yoon;JungWon Byun;SoonJoong Kim
    • The Journal of Churna Manual Medicine for Spine and Nerves
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    • v.18 no.2
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    • pp.31-42
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    • 2023
  • Objectives This study aimed to conduct a systematic review evaluating the effectiveness of muscle energy technique(MET) in temporomandibular joint disorders (TMD). Methods Searches were conducted in 11 electronic databases until October 2023. Randomized controlled trials(RCT) comparing the effect of MET for TMD were included. All studies were evaluated using the Cochrane Risk of Bias tool. Results Nine documents that fulfilled all the criteria were obtained for analysis. All studies showed some concerns in high risk of bias, but showed a significant improvement in pain and maximum mouth opening compared to baseline of MET or control group. MET was not better than extracorporeal shock wave therapy or myofascial release in some outcomes. Conclusions MET seems to be an effective treatment for TMD in some regards, however, can be considered as an adjunct therapy which has weak evidence. Further studies are required due to the inconclusive data and poor homogeneity found in this review.

Chuna Manual Therapy for Headache : A Systematic Review and Meta-analysis (두통에 대한 추나요법의 효과 : 체계적 문헌고찰과 메타분석)

  • Kim, Dae-Hun;Hwang, Eui-Hyoung;Heo, In;Kim, Byung-Jun;Bae, Ji-Min;Kim, Jae-Kyu
    • The Journal of Churna Manual Medicine for Spine and Nerves
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    • v.10 no.2
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    • pp.1-12
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    • 2015
  • Objectives : To determine the effectiveness of Chuna manual therapy for headache Methods : We searched 6 electronic databases(Pubmed, CAJ, Oasis, RISS, DBPIA, KoreanTK) and 2 journals up to Oct 2015. We included randomized controlled trials(RCTs) using Chuna manual therapy for headache. The methodological quality of each RCT was assessed by the Cochrane risk of bias tool. Results : 9 RCT studies were eligible in our review. The meta-analysis of 6 studies showed favorable results for the use of Chuna manual therapy. High risk of bias were observed in all studies. Conclusions : Although there are favorable results with meta-analysis, our systematic review arehighly dependent on the single source of Chinese electrical database, CAJ. Now limited evidence is available tosupport Chuna manual therapy for headache and further well-designed RCTs should be encouraged.

Effect of Kegel Exercise to Prevent Urinary and Fecal Incontinence in Antenatal and Postnatal Women: Systematic Review (임신 및 출산 여성의 요실금 및 대변실금 예방을 위한 케겔운동의 효과: 체계적 문헌 고찰)

  • Park, Seong-Hi;Kang, Chang-Bum;Jang, Seon Young;Kim, Bo Yeon
    • Journal of Korean Academy of Nursing
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    • v.43 no.3
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    • pp.420-430
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    • 2013
  • Purpose: The aim of this study was to review the literature to determine whether intensive pelvic floor muscle training during pregnancy and after delivery could prevent urinary and fecal incontinence. Methods: Randomized controlled trials (RCT) of low-risk obstetric populations who had done Kegel exercise during pregnancy and after delivery met the inclusion criteria. Articles published between 1966 and 2012 from periodicals indexed in Ovid Medline, Embase, Scopus, KoreaMed, NDSL and other databases were selected, using the following keywords: 'Kegel, pelvic floor exercise'. The Cochrane's Risk of Bias was applied to assess the internal validity of the RCT. Fourteen selected studies were analyzed by meta-analysis using RevMan 5.1. Results: Fourteen RCTs with high methodological quality, involving 6,454 women were included. They indicated that Kegel exercise significantly reduced the development of urinary and fecal incontinence from pregnancy to postpartum. Also, there was low clinical heterogeneity. Conclusion: There is some evidence that for antenatal and postnatal women, Kegel exercise can prevent urinary and fecal incontinence. Therefore, a priority task is to develop standardized Kegel exercise programs for Korean pregnant and postpartum women and make efficient use of these programs.

Analysis of Clinical Researches on Traditional Medicine Treatment for Behcet's Disease in Korea, China, and Japan (한중일의 베체트병에 대한 한의약 임상연구 분석)

  • Yong, Seokil;Gu, Hyungyung;Kim, Daehun;Sohn, Kyungwoo;Yun, Youngju
    • Journal of Society of Preventive Korean Medicine
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    • v.18 no.1
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    • pp.67-82
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    • 2014
  • Objective : To find a treatment strategy, this study aimed to review and compare the clinical studies of Korea, China, and Japan on traditional medicine treatment for Behcet's disease. Method : Literature searches were performed on six databases in each country and English databases, such as OASIS, KoreanTK, CNKI, J-STAGE, PubMed, and Cochrane CENTRAL. In addition, using the limited keywords, the area was restricted to traditional medicine treatment, but the period was not limited. Studies were categorized according to the study design and we analyzed the difference of treatment among three countries. Results : One hundred and forty-one clinical studies met our inclusion criteria: 11 studies in Korea, 15 in Japan, 115 in China. Randomized controlled trials (RCT) have increased in China, however, no RCT was reported in Korea and Japan. The method of treatment was mainly traditional herbal medicine in all the three countries, but there were significant differences in the field of syndrome identification and prescription among countries. The studies in China made use of most various treatment modalities and reported the highest effectiveness. Conclusion : Traditional medicine treatment showed a considerable effect for improving various symptoms of Behcet's disease. However, more research for answering the safety and well-designed studies considering characteristics of Behcet's disease should be performed to evaluate the effectiveness of traditional medicine treatment objectively in the future.

Efficacy of intralipid administration to improve in vitro fertilization outcomes: A systematic review and meta-analysis

  • Han, E Jung;Lee, Hye Nam;Kim, Min Kyoung;Lyu, Sang Woo;Lee, Woo Sik
    • Clinical and Experimental Reproductive Medicine
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    • v.48 no.3
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    • pp.203-210
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    • 2021
  • We performed a systematic review and meta-analysis to evaluate whether intralipid administration improved the outcomes of in vitro fertilization. Online databases (PubMed, Cochrane Library, Medline, and Embase) were searched until March 2020. Only randomized controlled trials (RCTs) that assessed the role of intralipid administration during in vitro fertilization were considered. We analyzed the rates of clinical pregnancy and live birth as primary outcomes. Secondary outcomes included the rates of chemical pregnancy, ongoing pregnancy, and missed abortion. We reviewed and assessed the eligibility of 180 studies. Five RCTs including 840 patients (3 RCTs: women with repeated implantation failure, 1 RCT: women with recurrent spontaneous abortion, 1 RCT: women who had experienced implantation failure more than once) met the selection criteria. When compared with the control group, intralipid administration significantly improved the clinical pregnancy rate (risk ratio [RR], 1.48; 95% confidence interval [CI], 1.23-1.79), ongoing pregnancy rate (RR, 1.82; 95% CI, 1.31-2.53), and live birth rate (RR, 1.85; 95% CI, 1.44-2.38). However, intralipid administration had no beneficial effect on the miscarriage rate (RR, 0.75; 95% CI, 0.48-1.17). A funnel plot analysis revealed no publication bias. Our findings suggest that intralipid administration may benefit women undergoing in vitro fertilization, especially those who have experienced repeated implantation failure or recurrent spontaneous abortion. However, larger, well-designed studies are needed to confirm these findings.

The effects of maternal-child nursing clinical practicum using virtual reality on nursing students' competencies: a systematic review (가상현실을 이용한 모아간호 실습교육이 간호 대학생의 실습역량에 미치는 영향: 체계적 문헌고찰)

  • Hwang, Sungwoo;Kim, Hyun Kyoung
    • Women's Health Nursing
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    • v.28 no.3
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    • pp.174-186
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    • 2022
  • Purpose: This study aimed to investigate the effects of virtual reality used in maternal-child nursing clinical practicums on nursing students' competencies through a systematic review. Methods: The inclusion criteria were peer-reviewed papers in English or Korean presenting analytic studies of maternal-child nursing practicums using virtual reality. An electronic literature search of the Cochrane Library, CINAHL, EMBASE, ERIC, PubMed, and Research Information Sharing System databases was performed using combinations of the keywords "nursing student," "virtual reality," "augmented reality," "mixed reality," and "virtual simulation" from February 4 to 15, 2022. Quality appraisal was performed using the RoB 2 and ROBINS-I tools for randomized controlled trials (RCTs) and non-RCTs, respectively. Results: Of the seven articles identified, the RCT study (n=1) was deemed to have a high risk of bias, with some items indeterminable due to a lack of reported details. Most of the non-RCT studies (n=6) had a moderate or serious risk of bias related to selection and measurement issues. Clinical education using virtual reality had positive effects on knowledge, skills, satisfaction, self-efficacy, and needs improvement; however, it did not affect critical thinking or self-directed learning. Conclusion: This study demonstrated that using virtual reality for maternal-child nursing clinical practicums had educational effects on a variety of students' competencies. Considering the challenges of providing direct care in clinical practicums, virtual reality can be a viable tool that supplements maternal-child nursing experience. Greater rigor and fuller reporting of study details are required for future research.

Recent Domestic and International Trends on Non-Surgical Treatment of Lumbar Spinal Stenosis (요추 척추관 협착증의 비수술적 치료에 대한 최근 국내·외 연구 동향)

  • Kim, Mi-Hyun;Park, Eun-Sang;Hwang, Hyeon-Ho;Lee, Yeo-Gyeong;Song, Geum-Ju;Kwon, Mi-Ri;Kang, Jun-Hyuk
    • Journal of Korean Medicine Rehabilitation
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    • v.31 no.3
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    • pp.1-17
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    • 2021
  • Objectives The present study examined the recent domestic and international trends of non-surgical treatment of lumbar spinal stenosis (LSS). Methods The studies on non-surgical treatment of LSS were investigated via searching Korean web databases and PubMed. As a result, 39 studies were analyzed according to the authors, the types of study, the relationship to surgical treatment and the method of treatment. Results The first authors' occupations were identified as 17 doctors, 12 Korean medicine doctors, six physiotherapists, three chiropractic doctors and one doctor of science. The most common type of study in Korea was the case report and most of the studies were retrospective. Overseas, there were many prospective or experimental studies including randomized controlled trials (RCT). In Korea, non-surgical treatment was performed independently of surgical treatment in most cases. Among non-surgical treatments, the most researched treatment was traditional Korean medicine (TKM), followed by injection therapy, exercise therapy, and physical therapy. Conclusions Through this review, we can determine the effectiveness of TKM and its research direction. TKM should be studied experimentally including RCT and it should be conducted not only on acupuncture, but also on other treatment methods such as acupotomy, chuna, and herbal medicine. It is also necessary to conduct studies on TKM before and after surgery to compare the effects of surgery and TKM together, as well the effects on non-surgical treatments.