• Preventive Nutrition and Food Science
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• 제22권3호
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• pp.203-210
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• 2017

The antioxidant and antimicrobial activities of three kinds of strawberry ethanol extracts from Robus corchorifolius L. f. (RCL), Rubus parvifolius L. var. parvifolius (RPL), and Duchesnea chrysantha Miq. (DCM) were investigated. The RPL was highest (P<0.05) in phenolic, flavonoid, and anthocyanin contents. 2,2-Diphenyl-1-picrylhydrazyl and 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) radical scavenging activities of RPL and DCM extracts were higher than that of RCL (P<0.05). Hydrogen peroxide scavenging activity of RPL was high compared to DCM and RCL (P<0.05). RCL exhibited a significant (P<0.05) potent antioxidant activity in nitric oxide radical inhibition. Inhibition diameter zone (nearest mm) of extracts against the test bacteria ranged from 11.5 in RCL to 12.5 in DCM against Staphylococcus aureus, from 10.5 in RCL to 13.5 in DCM against Streptococcus pneumoniae, from 8.5 in DCM to 10.5 in RCL against Escherichia coli, and the same inhibition of 10 mm in three of the extracts against Klebsiella pneumoniae. However, there was no inhibition against fungi Aspergillus niger and Candida albicans. Three of the extracts had the same minimum inhibitory concentration values of 12.50, 12.50, and $6.25{\mu}g/mL$ against S. aureus, K. pneumoniae, and S. pneumoniae, respectively. On the other hand, MIC values of 12.50, 12.50, and $6.50{\mu}g/mL$ were recorded for RPL, DCM, and RCL against E. coli, respectively. The result of present study revealed that extracts from three kinds of strawberries could be potential candidates as antioxidant and antimicrobial sources for functional food industries.

• 대한한의학회지
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• 제34권1호
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• pp.89-102
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• 2013

Objectives: This study aimed to evaluate the effects of root of Curcumin longa (RCL) on LPS-induced COPD (chronic obstructive pulmonary disease) model. Materials and Methods: Extract of RCL was treated to RAW 264.7 cells and LPS-induced COPD mouse model. Then, various parameters such as cell-based protective activity, airflow limitation, accumulation of immune cells and histopathological finding were analyzed. Results: RCL showed a protective effect on LPS-induced cytotoxicity in RAW 264.7 cells. RCL treatment also revealed a protective effect on LPS-induced lung injury in a COPD mouse model. This effect was demonstrated via the reduction of accumulation of immune cells and pathophysiological regulation of caspase 3, elastin and collagen in lung tissue. Conclusions: These data suggest that RCL has a pharmaceutical property on lung injury. This study provides scientific evidence for the efficacy of RCL for clinical application to COPD patients.

• 한국응용약물학회:학술대회논문집
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• 한국응용약물학회 2003년도 Annual Meeting of KSAP : International Symposium on Pharmaceutical and Biomedical Sciences on Obesity
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• pp.99-99
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• 2003

We studied the effect of Rubus croceacanthus Leveille (RCL) on mast cell-mediated anaphylactic reactions. RCL inhibited compound 48/80-induced systemic anaphylactic shock. When RCL was given at concentrations ranging from 0.01 to 1 mg/$m\ell$, the histamine release from rat peritoneal mast cells induced by compound 48/80 was reduced in a dose-dependent manner. RCL also inhibited passive cutaneous anaphylaxis activated by anti-dinitrophenyl IgE. In addition, RCL inhibited phorbol 12-myristate 13-acetate and A23187-induced tumor necrosis factor-${\alpha}$ secretion from human mast cell line HMC-1 cells. These results indicate that RCL may possess a strong anti-anaphylactic activity.

• 약학회지
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• 제49권3호
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• pp.217-224
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• 2005

Human Immunodeficiency Virus type 1 (HIV-l) based lentivirus vector has demonstrated great potential as gene therapy vectors mediating efficient gene delivery and long-term transgene expression in both dividing and nondividing cells. However, for clinical studies it must be confirmed that vector preparations are safe and not contaminated by replication competent lentivirus (RCL) related to the parental pathogenic virus, HIV-l. In this study, we would like to establish the method for titration and RCL detection of lentivirus vector. The titration was determined by vector expression containing the green fluorescent protein, GFP in transduced cells. The titer was $1{\times}10^7$ Transducing Unit/ml in the GFP expression assay and $8.9{\times}10^7$ molecules/ml in the real-time PCR. Also, for the detection of RCL, we have used a combination method of PCR and p24 antigen detection. First, PBS/psi and VSV-G region in the genomic DNA of transduced cells was detected by PCR assay. Second, transfer and expression of the HIV-1 gag gene was detected by p24 ELISA. In an attempt to amplify any RCL, the transduced cells were cultured for 3 weeks (amplification phase) and the supernatant of amplified transduced cell was used for the second transduction to determine whether a true RCL was present (indicator phase). Analysis of cells and supernatant at day 6 in indicator phase were negative for PBS/psi, VSV-G, and p24 antigen. These results suggest that they are not mobilized and therefore there are no RCL in amplification phase. Thus, real-time PCR is a reliable and sensitive method for titration and RCL detection of lentivirus vector.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 2003년도 ICCAS
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• pp.1736-1740
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• 2003

POSCO Kwang-Yang Works #2 Cold Rolling Mill RCL has the main hydraulic system that controlled on/off control method. In the aspect of the consumption of electrical energy this system has some problem. So, we present a continuous control method instead of on/off control method that controls the pressure of main hydraulic system with saving the electric energy.

• Journal of Radiation Protection and Research
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• 제22권1호
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• pp.29-33
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• 1997

중성자교정실내에서 $D_2O$ 감속 $^{252}Cf$중성자선원을 사용하여 계측기를 교정할 때는 그 계측기에 대한 교정실산란보정 인자를 미리 결정하여야 한다. 이러한 교정실산란보정인자는 계측기의 종류, 교정거리, 교정실형태에 따라 다르게 결정된다. 본 연구에서는 한국원자력연구소에서 운영하는 2차 표준중성자교정실에서 한가지의 열형광선량계와 2가지의 구형검출기에 대한 교정실산란보정인자를 실험적으로 결정하였고 본소의 2차 표준중성자교정실조건에 의하여 이론적으로 예측한 값과 비교하였다. 비교한 결과 실험하여 얻어진 상기의 3가지 계측기에 대한 교정실산란보정인자가 이론적으로 예측한 결과와 최대 약 10% 이내에서 일치하였다.

• 분석과학
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• 제10권1호
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• pp.53-59
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• 1997

$Cl^-$형 음이온 교환수지에서 희토류-EDTA 용리액을 사용하여 희토류 원소 혼합물 중의 원하는 한 원소를 분리 회수하는 연구를 하였다. 음이온 교환수지에 $Sm^{3+}$, $La^{3+}$, $Ce^{4+}$의 EDTA-착물을 흡착시키고, Sm-EDTA 용액으로 용리시키면, 수지에 흡착된 희토류 원소 중 $Sm^{3+}$ 외의 희토류 원소는 용리된다. 수지에 남아 있는 $Sm^{3+}$는 단계적으로 1M HCl 용액으로 용리시켜 분리하였다. Sm-EDTA 용액 대신 La-EDTA 용액으로 용리시키면 $Sm^{3+}$과 $Ce^{4+}$이 $La^{3+}$과 같이 용리되어 완전한 분리가 되지 않았고, Ce-EDTA 용액으로 용리시킬 때도 분리가 불가능하였다. Sm-EDTA 용액으로 용리시킬 때 용리 구조는 다음과 같다. 흡착과정 : $RCl+Ln-Y^-{\leftrightarrows}RLnY+Cl^-$, Sm-EDTA 용리 : $RLnY+Sm-Y^-{\leftrightarrows}RSmY+Ln-Y^-$, HCl 용리 : $RSmY+HCl{\leftrightarrows}RCl+Sm-Y^-$.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 1997년도 한국자동제어학술회의논문집; 한국전력공사 서울연수원; 17-18 Oct. 1997
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• pp.1573-1576
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• 1997

In this paper we present an associative menory network(AMN) controller for learning of robot trajectories. We use AMN controller in order to improve the performance of conventional learning control, e.g. RCL, which had studied by Sadegh et al. Computer simulations show the feasibility and effectiveness of the proposed AMN controller.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제13권10호
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• pp.4971-4987
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• 2019

Node localization is the basic task of underwater wireless sensor networks (UWSNs). Most of the existing underwater localization methods rely on ranging accuracy. Due to the special environment conditions in the ocean, beacon nodes are difficult to deploy accurately. The narrow bandwidth and high delay of the underwater acoustic communication channel lead to large errors. In order to reduce the ranging error and improve the positioning accuracy, we propose a localization algorithm based on ranging correction and inertial coordination. The algorithm can be divided into two parts, Range Correction based Localization algorithm (RCL) and Inertial Coordination based Localization algorithm (ICL). RCL uses the geometric relationship between the node positions to correct the ranging error and obtain the exact node position. However, when the unknown node deviates from the deployment area with the movement of the water flow, it cannot communicate with enough beacon nodes in a certain period of time. In this case, the node uses ICL algorithm to combine position data with motion information of neighbor nodes to update its position. The simulation results show that the proposed algorithm greatly improves the positioning accuracy of unknown nodes compared with the existing localization methods.

• 한국산업안전학회:학술대회논문집
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• 한국안전학회 1998년도 춘계 학술논문발표회 논문집
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• pp.257-262
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• 1998

In order to understand the characteristics of electrostatic discharge (ESD) by a charged human body, a dynamic analysis method based on RCL circuit and a quasi-static analysis method based on two-body model are introduced. In this paper, these methods calculate waveforms, discharge energy and potential difference to analyze the ESD phenomena from given initial conditions and geometry. Results are compared and discussed.