• Asian Pacific Journal of Cancer Prevention
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• 제16권1호
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• pp.363-365
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• 2015

Background: Kidney cancer is the third most frequent urologic cancer in Lebanon after prostate and bladder cancer, accounting for 1.5% of all diagnosed cancers. In this paper, we report the histologic characteristics and distribution of kidney cancer, never described in Lebanon or the Middle East. Materials and Methods: Pathology results of operated kidney cancer were collected during a two year period (2010-2011) from two different Lebanese hospitals (Hotel-Dieu de France University Hospital and Saint Joseph Hospital). A total of 124 reports were reviewed and analyzed according to WHO classification of 2009. Results: The 124 patients diagnosed with kidney cancer had a median age of 62.4 [18-86], 75% being men and 25% women. Some 71 % of the lesions were renal cell carcinoma (RCC), 25.8% had a urothelial histology, 1.6% were lymphomas and 1.6% were metastases to the kidney. Patients having RCC had a median age of 60.3 [18-85], 77.3% were men and 22.7% women. Of the RCCs, 59.1% were clear cell carcinoma, 22.7% papillary, 11.4% chromophobic, 3.4% rom the collecting ducts of Bellini and 3.4% were not otherwise classified. Conclusions: Histological distribution of Lebanese kidney cancer seems unusual when compared to the literature. The percentage of urothelial renal pelvis tumors is strikingly high. Moreover, clear cell carcinoma accounts for only 59.1% of RCCS in contrast to the 75% described elsewhere, while papillary carcinoma represents more than 22.7% compared to 10%.

• Asian Pacific Journal of Cancer Prevention
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• 제13권10호
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• pp.4963-4965
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• 2012

Objective: To diagnose renal cell carcinoma at early stages and for better prognosis, the main objective of our current study was to understand any association with diabetes with relation to age, gender, history of disease, diabetic laboratory parameters, tumor size and grade. Materials and Methods: This hospital based study was carried out using data retrieved from the register maintained in the Department of Biochemistry of Nepalese Army Institute of Health Sciences between $1^{st}$ December, 2011 and $31^{st}$ May, 2012. The variables collected were age, gender, HbA1c, serum creatinine, fasting blood glucose. One way ANOVA was applied to examine statistical significance of differences between groups. The LSD post hoc test was used for the comparison of means of case groups. Results: Of the total 140 cases of renal cell carcinoma, 79 patients were also suffering from diabetes mellitus. The number of females (47) was more in diabetic RCC patients when compared to males (32). Significance was observed in levels of serum creatinine for tumor size >10cm ($0.0001^*$). The highest value of glycated hemoglobin (8.9%) and fasting blood sugar(148.3mg/dl)in cases of renal cell carcinoma along with diabetes mellitus was found in tumour size of 1-5cm. Conclusion: Diabetes mellitus has independent prognostic significance in RCC in relation to tumour size and grade.

• 한국임상수의학회지
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• 제28권5호
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• pp.526-529
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• 2011

새김질동물류의 상완머리동맥은 대동맥활에서 분지하는 유일한 동맥으로 왼빗장밑동맥, 양목동맥 또는 왼 오른온목동맥, 오른빗장밑동맥을 분지한다. 이런 분지 양상은 발생초기에 왼온목동맥과 왼빗장밑동맥이 심장 내림현상에 따라 차례로 앞쪽으로 이동하여 일명 무명동맥과 합류함으로써 생긴다. 본 증례의 약 31개월령 한국고라니 암컷에서는 상완머리동맥과 왼빗장밑동맥이 합쳐져 외형상 하나의 혈관을 이루고 있었으나 두 동맥의 중간막 안쪽층이 남아 있었으며, 이에 따라 불완전한 상완머리동맥으로 남아 있었음을 볼 수 있었다. 이러한 기형은 왼빗장밑동맥이 정상적으로 이동 하였으나 합쳐지는 과정이 불완전하게 된 경우라고 볼 수 있으며, 한국고라니에서 처음 보고하는 바이다.

• Food Science and Biotechnology
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• 제17권4호
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• pp.687-691
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• 2008

This study was performed to investigate the taste composition and biological activities of cheonggukjang containing Rubus coreanum to improve cheonggukjangs' flavor and consumption. In R. corenum cheonggukjang (RCC), the total content of soluble sugars, including glucose, fructose, maltose, and sucrose, was 1,052.1 mg/100 g. Glutamic acid, phenlylalanine, leucine, cystine, and tyrosine were the major amino acids, and the ratio of sweet to bitter components was higher in RCC than in general cheonggukjang (GC). The 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activities of the extracts, in decreasing order, were found to be: ethanol extract> water extract> chloroform extract, at all concentrations. The water extract had the highest SOD-like activity (10.2%) at a concentration of 0.5 mg/mL, whereas the chloroform extract showed the highest SOD-like activity (19.1%) at a concentration of 2 mg/mL. The nitrite scavenging ability was higher at pH 1.2 than at pH 3.0 or 6.0, and had a positive correlation with the extract concentration. The chloroform extract had the highest nitrite scavenging ability (84.6%) at a concentration of 2 mg/mL and pH 2.0.

• Advances in concrete construction
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• 제5권6호
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• pp.625-638
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• 2017

The flexural behavior of Fiber reinforced polymer (FRP) sheets has gained much research interest in the flexural strengthening of reinforced concrete beams. The study on flexure includes various parameters like increase in strength of the member due to the externally bonded (EB) Fiber reinforced polymer, crack patterns, debonding of the fiber from the structure, scaling, convenience of using the fibers, cost effectiveness, etc. The present work aims to study experimentally about the reasons behind the failure due to flexure of an externally bonded FRP concrete beam. In the design of FRP-reinforced concrete structures, deflection control is as critical as much as flexural strength. A numerical model is created using Finite element (FEM) software and the results are compared with that of the experiment.

• Annals of Coloproctology
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• 제34권6호
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• pp.286-291
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• 2018

Purpose: Stage-IIIC colon cancer is an advanced disease; however, its oncologic outcomes and prognostic factors remain unclear. In this study, we aimed to determine the predictors of disease-free survival (DFS) in patients with stage-IIIC colon cancer. Methods: From a multicenter database, we retrospectively enrolled 611 patients (355 men and 256 women) who had undergone a potentially curative resection for a stage-IIIC colon adenocarcinoma between 2003 and 2011. The primary endpoint was the 5-year DFS. Results: The median age was 62 years; 213 and 398 patients had right-sided colon cancer (RCC) and left-sided colon cancer (LCC), respectively. The 5-year DFS in all patients was 52.0%; median follow-up time was 35 months (range, 1-134 months). A multivariate Cox regression revealed that female sex (hazard ratio [HR], 1.50; 95% confidence interval [CI], 1.19-1.90; P < 0.01), right-sided tumor location (HR, 1.65; 95% CI, 1.29-2.11; P < 0.01), lymphatic invasion (HR, 1.52; 95% CI, 1.08-2.15; P < 0.01) and a high (${\geq}0.4$) metastatic lymph node ratio (HR, 3.72; 95% CI, 2.63-5.24; P < 0.01) were independent predictors of worse 5-year DFS. Female patients with RCC were 1.79 fold more likely to experience recurrence than male patients with LCC. Conclusion: Female sex and right-sided tumor location are associated with higher tumor recurrence rates in patients with stage-IIIC colon cancers. Aggressive treatment and close surveillance should be planned for patients in these groups.

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 2006년도 하계학술대회 논문집 Vol.7
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• pp.224-225
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• 2006

$BaTiO_3$ powder를 epoxy/solvent에 혼합한 슬러리와 solvent에 혼합한 슬러리의 분산 특성을 평가하기 위하여 분산제인 silane을 $BaTiO_3$ powder 표면에 코팅한 powder를 이용하여 분산실험을 진행하였다. Silane 표면 코팅 량에 따른 $BaTiO_3$ 슬러리와 $BaTiO_3$/epoxy 복합 슬러리의 분산 특성은 서로 다른 경향으로 나타남을 확인하였으며, silanae 최적 첨가량은 $BaTiO_3$/solvent 슬러리의 경우 0.3~0.5 wt%, $BaTiO_3$/epoxy/solvent 슬러리의 경우 1wt% 이상 첨가한 조건이었다. 또한 분산성 측정의 방법으로 점도 측정 방법과 함께 표면 거칠기 측정 방법의 가능성을 확인하였다.

• 농업과학연구
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• 제20권2호
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• pp.109-116
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• 1993

본(本) 실험(實驗)은 목초지(牧草地)에 있어서 혼파(混播)의 경우 화본과목초(禾本科牧草)와 콩과목초(科牧草)를 혼파할 때 그에 따른 생산성(生産性)과 경합관계(競合關係)를 분석(分析)하고 화본과와 콩과목초를 일정한 비율로 파종하였 때 파종비율에 따른 초종들간의 경합에 미치는 영향을 조사하기 위해 실시하였던 바 그 결과를 요약하면 다음과 같다. 1. 건물중(乾物重)은 단파(單播)했을 때 톨페스큐구에서 $1105g/m^2$으로 가장 많았으며 화이트클로바에서 $503g/m^2$으로 가장 적었다. 그리고 혼파의 경우는 톨페스큐-레드클로바 (1:0.1)구(區)가 $1500g/m^2$으로 가장 높았으며, 오차드그라스-화이트클로바 (1:0.1)구(區)가 $844g/m^2$으로 가장 낮았다. 2. LAI는 혼파구(混播區)에서 단파구(單播區)의 화본과(禾本科) 초종(草種)보다 증가하였는데 단파구(單播區)의 오차드그라스에서 9.3, 레드클로바에서 12.5, 톨페스큐는 6.5, 화이트클로바는 8.1을 보인 반면, 혼파구(混播區)에서는 오차드그라스-레드클로바구에서 10.7-12.1, 오차도그라스-화이트클로바구에서 9.2-12.3, 톨페스큐-레드클로바구에서 9.2-12.4, 톨페스큐-화이트클로바구에서 7.8-8.1을 보였다. 3. 목초(牧草)의 수량(收量)으로 살펴본 단파(單播)에 비해 혼파(混播)의 유리함을 비교하는 지수(指數)로서 RYT를 살펴보면 오차드그라스-레드클로바의 1:0.1파(播) 종구(種區)와 1:1파(播) 종구(種區)를 제외하고는 RYT가 1.0보다 모두 커 혼파(混播)가 단파(單播)에 비하여 유리한 것으로 나타났다. 4. 콩과목초(科牧草)의 파종비율(播種比率)이 높을수록 화본과목초(禾本科牧草)의 경합력(競合力)이 떨어지는데 화이트클로바와의 혼파(混播)에서 레드를로바보다 그 정도가 더 컸으며 톨페스큐가 오차드그라스보다 콩과목초(科牧草)에 대한 경합력(競合力)이 큰 것으로 나타났다. 5. 화본과목초(禾本科牧草)의 콩과목초(科牧草)에 대한 RCC를 살펴보면 콩과목초(科牧草)의 파종비율(播種比率)이 높을수록 화본과목초(禾本科牧草)는 생육(生育)이 억제(抑制)되었는데 레드클로바보다는 화이트 클로바와의 혼파(混播)에서 더 크게 나타났다.

• 방송공학회논문지
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• 제23권5호
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• pp.669-681
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• 2018

본 논문에서는 고해상도 자궁경부암 세포사진을 CNN(Convolution Neural Network)을 통해 효과적으로 인식 및 분류하는 방법을 소개한다. 이때 고려되는 세포의 종류는 Ascus, Inflammation, RCC, Normal 로 네 가지가 있다. 본 논문에서는 먼저 기존의 고해상도 이미지를 분류하는 알고리즘을 소개하고, 이 방법을 이용하여 고해상도 세포사진을 분류하는 과정에서 어떤 정보의 손실이 발생하는지 분석한 후, 이를 해결하기 위한 방법을 제시한다. 이를 위해서 본 논문에서 제안하는 학습 모델에서는 dilated convolution을 이용하여 고해상도 사진의 정보의 손실을 최소한으로 줄임과 동시에 학습속도 빠르게 하는 알고리즘을 제시한다. 또한 이미지 전처리 과정으로 임계치를 사용함으로써 암세포를 판단하는데 혼란을 줄 수 있는 부분을 제거함으로써 인식률을 향상시킨다. 본 논문에서 제시되는 실험 결과를 통해, 제안한 알고리즘이 기존 기술보다 높은 인식률을 제공하는 것을 확인할 수 있었다.

• Asian Pacific Journal of Cancer Prevention
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• 제16권11호
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• pp.4665-4669
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• 2015

The aim of this study was to assess the diagnostic value of RASSF1A methylation in renal cell carcinoma. Systematically search were performed using the Pubmed, ProQest and Web of Science for all articles on the association between RASSF1A methylation and renal cell carcinoma before 15 April 2015. After the filtration, 13 studies involving 677 cases and 497 controls met our criteria. Our meta-analysis suggested that hypermethylation of RASSF1A gene was associated with the increased risk of RCC(OR:4.14, 95%CI:1.06-16.1). Stratified analyses showed a similar risk in qualitative detection method(OR:28.4, 95%CI:10.2-79.6), body fluid sample(OR:12.8, 95%CI:5.35-30.8), and American(OR:10.5, 95%CI:1.97-55.9). Our result identified that RASSF1A methylation had a strong potential in prediction the risk of Renal cell carcinoma.