• 대한임상검사과학회지
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• 제48권2호
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• pp.109-113
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• 2016

분석전 변이로 인하여 검사실은 오류에 직면하게 되고 많은 요인들은 환자의 검사결과에 영향을 미치게 된다. 다양한 진공채혈관은 신속하게 분리하고 방치된 검체의 용혈을 방지한다. 그러나 진공채혈관의 상태에 따라 몇 가지 제한점들이 발생하는데 이러한 문제점을 알아보기 위해 다양한 진공채혈관을 이용해 혈구산정검사로 비교 평가하였다. 유통기한별 검사결과에서는 백혈구(WBC)와 혈소판(PLT)의 값에서 0.24, 0.21로 큰 변이계수를 나타냈고 상관성에서는 백혈구(WBC), 혈소판(PLT), 적혈구(RBC)의 값이 유의성을 보였다(p<0.01). 한편 각 3사의 비교평가에서는 백혈구(WBC), 혈소판(PLT)의 값에서 0.27, 0.21로 가장 큰 변이계수를 나타냈고, 상관성에서는 각 3사가 모두 백혈구(WBC), 혈소판(PLT), 혈소판분포폭(PDW)의 값에서 높은 유의한 차이를 보였다(p<0.01) 그러나 G사와 B사는 혈소판(PLT), 혈소판분포폭(PDW)의 값에서는 낮은 유의한 차이를 보였다(p<0.05). 결론적으로 진공채혈관의 상태에 따른 분석의 안정성을 위해 적절한 진공채혈관의 분석평가가 이루어져야 한다.

• 사상체질의학회지
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• 제17권2호
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• pp.74-84
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• 2005

1. Objectives The purpose of this study is to find out effects of Choeongsimyeonja-tang and Taeumjowi-tang on the against decline of physical function as aging. 2. Methods In Wistar rat 10, 30, 50 week and 40 week Choeongsimyeonja-tang & Taeumjowi-tang between 10 weeks form condition change of weight, change of intestine weight, hematology, blood chemistry, research result about serum content following conclusion get. 3. Results and Conclusions 1. Observed gain in weight than control group form of Cheongsimyeonja-tang & Taeumjowi-tang to aged Wistar rat. 2. Is thought to promote activation of living body action gaining intestine weight along with gain in weight. 3. Displayed decrease of MDA's content of serum than control group form of Cheongsimyeonja-tang & Taeumjowi-tang to aged Wistar rat. 4. Change that is Wistar rat's hematological value by aging according to 10, 30, 50 week WBC, RBC, Hgb, monocyces, eosinophil ere. increase, and HCT, PLT ere. showed tendency that decrease accorcling to old-week, and observed improvement that is hematological value than control group form of Cheongsimyeonja-tang & Taeumjowi-tang.5. Change that is Wistar rat's biochemical value by aging was measured highest in 50 week because ALT, AST, BUN, CRN, T-bili., T-chol., TG, TP, ALB, A/G. P ete. increase according to 10, 30, 50 week, and observed improvement that is biochemical value than control group form of Cheongsimyeonja-tang & Taeumjowi-tang. Is considered by being effect that Cheongsimyeonja-tang & Taeumjowi-tang living body function decline by aging by this result.

• 혜화의학회지
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• 제13권2호
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• pp.337-345
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• 2004

Using aged Wistar rat living body change by aging CheongSimYeonJaTang was each orally administrated and achieved research about aging control. In Wistar rat 10, 30, 50 week and 40 week CheongSimYeonJaTang between 10 weeks form condition change of weight, change of intestine weight, hematology, blood chemistry, research result about serum content following conclusion get. 1. Observed gain in weight than control group form of CheongSimYeonJaTang to aged Wistar rat. 2. Is thought to promote activation of living body action gaining intestine weight along with gain in weight. 3. Displayed decrease of MDA's content of serum than control group form of CheongSimYeonJaTang to aged Wistar rat. 4. Change that is Wistar rat's hematological value by aging according to 10, 30, 50 week WBC, RBC, Hgb, monocytes, eosinophil etc. increase, and HCT, PLT etc. showed tendency that decrease according to old-week, and observed improvement that is hematological value than control group form of CheongSimYeonJaTang. 5. Change that is Wistar rat's biochemical value by aging was measured highest in 50 week because ALT, AST, BUN, CRN, T-bili., T-chol, TG, TP, ALB, A/G, P etc. increase according to 10, 30, 50 week, and observed improvement that is biochemical value than control group form of CheongSimYeonJaTang. Is considered by being effect that CheongSimYeonJaTang living body function decline by aging by this result.

• 혜화의학회지
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• 제13권2호
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• pp.317-326
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• 2004

Administrating PalMoolGoonJaTang and SipIMiGwanJungTang to 40-weeks-(old Wistar rat for 10 weeks so, I researched into weight change, weight change of internal organ, and hemtological and serological changews. Then I got these conclusions. 1. Observed gain in weight than control group form of SipIMiGwanJungTang to aged Wistar rat. 2. Is thought to promote activation of living body action gaining intestine weight along with gain in weight. 3. Displayed decrease of MDA's content of serum than control group form of SipIMiGwan JungTang to aged Wistar rat. 4. Change that is Wistar rat's hematological value by aging according to 10, 30, 50 week WBC, RBC, Hgb, monocytes, eosinophil etc. increase, and HCT, PLT etc. showed tendency that decrease according to old-week, and observed improvement that is hematological value than control group form of SipIMiGwanJungTang 5. Change that is Wistar rat's biochemical value by aging was measured highest in 50 week because ALT, AST, BUN, CRN, T-bili., T-chol., TG, TP, ALB, A/G, P etc. increase according to 10, 30, 50 week, and observed improvement that is biochemical value than control group form of SipIMiGwanJungTang As those results, PalmoolGoonJaTang and SipIMiGwanJungTang are effective against dacline of physical function as aging. Moreover, considered to the serogical results, SipIMiGwanJungTang is much more effective than the other.

• 사상체질의학회지
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• 제25권1호
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• pp.14-22
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• 2013

Objectives The purpose of this study is to know hematologic characteristics of patients with stroke in Sasang Constitutional Medicine which will be helpful for the prevention and treatment of stroke. Methods We collected data from 111 patients who received treatment as a stroke inpatient at one Korean medicine hospital in Busan, Korea. A Sasang Constitutional Medicine(SCM) specialist diagnosed their Sasang Constitutional types based on the four diagnosis standard of SCM and herbal medicine reaction. Results of hematologic tests were classified according to gender, age, stroke types and Sasang Constitutional types and analysed by SAS system. Results 1. Male's mean value of RBC count, Hemoglobin and Hematocrit was lower than normal range. 2. The mean value of hsCRP of above age 65 group was 3.19 times significantly higher than under age 65 group. 3. The mean value of platelet of cerebral hemorrhage group was significantly higher than cerebral infarction group. 4. The mean value of triglyceride of Taeeumin was significantly higher than Soyangin and Soeumin. Conclusions For the prevention of stroke, appropriate treatment of stress, trauma and infections is needed and male require a regular and balanced meals. Especially Taeeumin need to eat small meals to avoid excessive accumulation of energy.

• 한방안이비인후피부과학회지
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• 제18권2호
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• pp.10-27
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• 2005

Objectives: To study the effectiveness of Sanpunggosamhwan(SGH) against Allergic Contact Dermatitis(ACD), the contact hypersensitivity assay, change of cutaneous shape, anti-allergic effect, anti-inflammatory effect, and the effect on skin barrier were observed. Methods: The 200g rats were divided into three groups of 15 rats. The first group is the Normal group which was applied Acetone olive oil only. The second group is the ACD group which has intentionally activated Allergic Contact Dermatitis by DNCB. The third group is the SGH group which was given medication of Sanpunggosamhwan extract after the induction of Allergic Contact Dermatitis by DNCB. Each group of rats was observed after 24, 48 and 72 hours. Results: I. With the result of contact hypersensitivity assay, at 24hours SGH group showed appreciably less ear swelling than ACD group. 2. Regarding general change of skin, SGH group showed less hyperplasia of epidermis, less damage of epidermis than ACD group. 3. Regarding the number of WBC, ACD group showed significantly less than normal and SGH group at 72 hours. 4. Regarding the number of RBC in blood, ACD and SGH group showed significantly more RBC than normal group at 24, 48, 72 hours. 5. Regarding the ratio of neutrophil in WBC, ACD and SGH group showed significantly high percentage than normal group at 24, 48 hours. 6. Regarding the ratio of lymphocyte in WBC, ACD and SGH group showed significantly high percentage than normal group at 48 hours. 7. Regarding the erythema, SGH group showed significantly more erythema than normal and ACD group at 48 hours. 8. Regarding the melanin, SGH group showed significantly less melanin than normal group at 24 hours.9. Regarding the skin hydration, SGH group showed significantly high value than and ACD group at 72 hours. 10. Regarding the skin pH, ACD group showed significantly high value than normal and SGH group af 24 hours. 11. Regarding the number of Total IgE, ACD and SGH group showed more Total IgE than normal. g개up at 24 hours. 12. At Electro microscope-morphologic changes of skin, the damage of epithelium was decreased and regeneration power of skin was increased in the SGH group. Conclusions: The Sanpunggosamhwan extract administration was effective on the mitigation of skin damage in rats with allergic contact dermatitis.

• 한국식품영양과학회지
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• 제12권4호
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• pp.368-373
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• 1983

제사공장(製絲工場)에서 부산물(副産物)로 나오는 번데기 단백질(蛋白質) 영양가(營養價)를 측정(測定)하기 위하여 이의 아미노산조성을 분석하였고 casein군(群)($D_1$), 대두단백질군(大豆蛋白質群)($D_2$), 대두단백질(大豆蛋白質)+20%번데기단백질군(蛋白質群)($D_3$), 대두단백질(大豆蛋白質)+40%번데기단백질군(蛋白質群)($D_4$), 번데기단백질군(蛋白質群)($D_5$)등(等) 5군(群)의 식이(食餌)로 나누어 동물실험(動物實驗)을 통(通)해 성장률(成長率), protein efficiency ratio, 장기중량(臟器重量), 그리고 hematology 및 total serum protein과 albumin의 함량을 측정(測定)하여 비교(比較)하였다. 번데기단백질(蛋白質)의 아미노산조성은 FAO의 provisional scoring pattern과 비교(比較)하였을 때 필수아미노산 조성이 우수하였으며 특히 lysine과 methionine의 함량이 높은 것은 곡류(穀類)와 두류(豆類) 단백질(蛋白質)에 부족(不足)한 필수아미노산을 보충(補充)하는데 좋은 단백질원(蛋白質源)으로 이용(利用)될 수 있다. 번데기단백질군(蛋白質群)의 체중증가량(體重增加量)과 단백효율(蛋白效率)은 대두단백질(大豆蛋白質)보다 우수하였으며 대두단백질(大豆蛋白質)에 첨가하는 양(量)의 증가(增加)에 따라 성장율과 단백효율(蛋白效率)이 증가(增加)하는 경향을 나타내었다. liver와 spleen의 총 중량은 대두단백질군(大豆蛋白質群)에 비(比)해 번데기단백질(蛋白質) 첨가군(群)에 있어서 더욱 높았으며 RBC, WBC, Hct과 Hb함량(含量)은 5식이군(食餌群) 모두 정상치(定常値)에 속(屬)하였다. Total serum protein과 albumin의 함량(含量)은 번데기단백질(蛋白質)의 첨가로 인해 현저히 증가(增加)하는 결과를 보여주고 있다. 이상의 결과로서 번데기단백질(蛋白質)은 대두단백질(大豆蛋白質)의 질(質)을 향상(向上)시킬 수 있는 단백질원(蛋白質源)으로 사료(思料)된다.

• Parasites, Hosts and Diseases
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• 제29권3호
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• pp.279-292
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• 1991

마우스에의 돼지회충(Ascaris strum) 또는 선모충(Trichinella spiralis) 감염이 sRBC에 대한 면역능에 미치는 영향을 조사한 다음 전처치로서 선모충을 감염시키거나 또는 cyclophosphamide를 투여하고 나서 돼지회충란을 경구투여하여 그 감염상태와 소장점막내 비만세포와의 관련성 그 리고 비특이 세포성 및 체액성 면역능을 함께 관찰하였다. 마우스에 1,000개의 돼지회충란을 경구투여한 바 지연형 과민반응과 로제트 형성능은 시일이 경과됨에 따라 점점 감소하기 시작하여 각각 5주, 6주에 최저치에 이른 다음 점점 상승하여 10주에 원상으로 복귀하였으며, 적현구 응집소가 및 용현소가는 점점 상승하여 3주에 최고치에 이른 다음 그 후 정상으로 복귀하였으며, 말초힐액내 호산구 및 소장접막내 비만세포 출현율은 각각 4주 및 2주에 최고치를 보였다. 한편, 유충은 1주후에 폐와 간으로부터 총 21.97%가 누수되었다. 마우스에 300마리의 선모충의 감염유충을 경구투여한 바 지연형 과민반응과 로제트 형성능은 시일이 경과 됨에 따라 점점 낮아져 각각 30일 및 21일에 전저치에 이른 다음 그 후부터 다소 높아지다가 70일 및 80일에 다시 일시적으로 낮아졌다. 그리고, 적현구 응집소가 및 용혈소가도 각각 21일 및 90일 에 다른 기보다 낮았으나, 말초혈액내 호산구 및 소장점막내 비만세포 출현율은 각각 40일째 및 14 일째에 다른 기보다 높았다. Cyclophosphamide를 400 mg/kg의 용량으로 마우스의 복륙 내에 투여한 바 체중이나 비장의 중량, 지연형 과민반응, 로제트 형성능, 적혈구 응집소가 및 용혈소가, 백현구 총수, 소장점막내 비만세포 출현율은 투여 후 1일에 비하여 5일에 현저하게 저하되었다가 10일에 다 시 증가하여 1일과 거의 비슷한 수준으로 복귀하였다. 말포혈액내 호산구 출현율은 시일이 경과함 에 따라 점점 낮아지는 경향이었다. 한편, 마우스의 복강 내에 cyclophosphamide를 투여한 다음 1일, 5일, 10일에 각각 1,000개의 감염성 돼지회충란을 투여하고 난 후 7일의 유충각수률은 1일 7.07%, 5일 14.94%, 10일 10.1%이었으며 대조군은 8.02%이었다 유모충을 마우스에 감작감염시키고 나서 각각 30일 및 70일 간격을 두고 감염성 돼지회충란을 도전감염시킨 바 참작감염후 37일과 도전감염후 7일의 시점에 있어서 지연형 과민반응과 로제트 형성능은 고도로 저하하였는데 반하여 소장점막내 비만세포 출현율은 고도로, 말초혈액내 호산구출현율, 적혈구 응집소가 및 용혈소가는 상당히 증가하였다. 이 시점에 있어서의 유충은 대조가 22.18% 회수되었는데 비하여 9.3%밖에 회수되지 않았다. 한편, 감작감염후 77일과 도전감염후 7일의 시점에 있어서 sRBC에 대한 면역능에 미치는 영향은 전자의 양상과 비슷하였는데 대조에 비하여 지연형 과민반응과 로제트 형성능이 현저하게 저하되었다. 이 시점에 있어서의 유충회수율은 대조가 10.5% 이었는데 비하여 8.3%이었다.

• The Journal of Korean Physical Therapy
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• 제17권3호
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• pp.403-412
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• 2005

The purpose of this investigation is examining how treatment for foot reflex massage affect the changes in body temperature and blood composition. The cases of experiment are 10 male(n=2) and female(n=8) who don't have special clinical problems. This is the process of experiment. First, we photograph the anterior part and posterior of the upper, lower half of the body with an infrared imaging system. Second, among same parts, we compare the temperature of the whole body before treatment for foot reflex massage with the temperature after it. Then we draw blood from the body and observe a change: in numerical value of blood before and after treatment. Before and after treatment, we come to measure temperature of the whole body, the numerical value of WBC, RBC, platelet, HCT, Hb through analysis of blood, and the result of AST(GOT), ALT(GPT), ALP, GGT through analysis of serum enzyme activity of blood. There were no significant differences in blood composition. In terms of SPSS statistic program, when we explain each numerical value before and after foot massage, the abdominal, the buttocks, the femoral region universally take successful results about a change in body temperature(p<0.05).

• 대한수의학회지
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• 제14권2호
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• pp.253-268
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• 1974

A total of 331 dairy cattle in Jeonnam area were examined for the breeding status and hematological values during the period from June to August. 1971 and 1974. The data obtained were analysed according to the status of breeding and the type of farm management. The results obtained in this work were summarized as follows: 1. 331 dairy cows were grouped as pregnant (63.81%) anestrus after parturition (12.45%), pregnancy unknown (11.48%), repeat breeder (10.32%), and others (1.94%). 2. The summery of reproductive histories and clinical examination were as follows. Average of calving interval was 16.5 months, interval from parturition to first breeding 97 days and postpartum interval to first estrus 72 days. Services per conception was 1.6 rate of postpartum estrus (60 days) 12.0%, and the rate of repent breeder 10.3%. 3. Generally, the blood values of RBC, Hb, serum total protein and A/G ratio were lower than those normal values, especially, the cows which showed abnormal values belonged to the repeat breeder and the unknown to conception group. The mean value for serum inorganic phosphorus was the normal value or hyperphosphatemia, on the other hand, the mean value for serum calcium of the repeat breeder group was the lowest than the other group. 4. Follow-up evaluations on the results of the laboratory tests strongly suggest that the problems of repeat breeder had a tendency to occur more frequently in the large herd (A and B type farm), and the Ca/P ratio of almost all the cows showed abnormal values.