• Earthquakes and Structures
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• v.14 no.1
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• pp.85-94
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• 2018

The paper focuses on the seismic responses of a hyperbolic cooling tower resting on soil foundation represented by the three-parameter Vlasov elastic soil model. The three-parameter soil model eliminates the necessity of field testing to determine soil parameters such as reaction modulus and shear parameter. These parameters are calculated using an iterative procedure depending on the soil surface vertical deformation profile in the model. The soil and tower system are modeled in SAP2000 structural analysis program using a computing tool coded in MATLAB. The tool provides a two-way data transfer between SAP2000 and MATLAB with the help of Open Application Programming Interface (OAPI) feature of SAP2000. The response spectrum analyses of the tower system with circular V-shaped supporting columns and annular raft foundation on elastic soil are conducted thanks to the coded tool. The shell and column forces and displacements are presented for different soil conditions and fixed raft base condition to investigate the effects of soil-structure interaction. Numerical results indicate that the flexibility of soil foundation leads to an increase in displacements but a decrease in shell membrane and column forces. Therefore, it can be stated that the consideration of soil-structure interaction in the seismic response analysis of the cooling tower system provides an economical design process.

• Earthquakes and Structures
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• v.12 no.6
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• pp.629-641
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• 2017

Foundation plays a significant role in safe and efficient turbo machinery operation. Turbo machineries generate harmonic load on the foundation due to their high speed rotating motion which causes vibration in the machinery, foundation and soil beneath the foundation. The problems caused by vibration get multiplied if the soil is poor. An improperly designed machine foundation increases the vibration and reduces machinery health leading to frequent maintenance. Hence it is very important to study the soil structure interaction and effect of machine vibration on the foundation during turbo machinery operation in the design stage itself. The present work studies the effect of harmonic load due to machine operation along with earthquake loading on the frame foundation for poor soil conditions. Various alternative foundations like rafts, barrette, batter pile and combinations of barrettes with batter pile are analyzed to study the improvements in the vibration patterns. Detailed computational analysis was carried out in SAP 2000 software; the numerical model was analyzed and compared with the shaking table experiment results. The numerical results are found to be closely matching with the experimental data which confirms the accuracy of the numerical model predictions. Both shake table and SAP 2000 results reveal that combination of barrette and batter piles with raft are best suitable for poor soil conditions because it reduces the displacement at top deck, bending moment and horizontal displacement of pile and thereby making the foundation more stable under seismic loading.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.41 no.12
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• pp.1801-1810
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• 2016

The OpenDaylight controller has been receiving significant attention as one of the enabling open source framework for SDN, and this paper analyzes the architecture and procedure of OpenDaylight based controller cluster. The OpenDaylight controller cluster uses shard based distributed datastore and Raft algorithm to maintain consistency among controllers inside a cluster. The performance evaluation analyzes the leader re-election time as well as latencies of CRUD and Routed RPC according to cluster size, shard role, and sharding strategy, and we discuss the optimal operation strategy for OpenDaylight controller cluster.

• Journal of the Society of Disaster Information
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• v.13 no.2
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• pp.130-138
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• 2017

The connector of the complex behavior is to connect the individual piles of the pile to the lower foundation of the oil sand plant where the floating foundation is used. In this study, to verify the shape of a connector of the complex behavior for applying the advantages of existing group pile and piled raft foundation to an oil sand plant, a scaled model was constructed to measure the behavior of the load.

• Journal of Life Science
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• v.16 no.6
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• pp.955-959
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• 2006

A dynamic cycle of addition and removal of O-linked N-acetylglucosamine (O-GlcNAc) at serine and threonine residues is emerging as a key regulator of nuclear and cytoplasmic protein activity. In this work, immunocytochemistry was carried out to investigate the subcellular expression of GlcNAc kinase (NAGK, EC 2.7.1.59) that catalyzes the phosphorylation of GlcNAc to GlcNAc 6-phosphate. Immunostainings of cultured rat hippocampal neurons revealed patchy or punctate distribution of NAGK. When NAGK is doublestained with caveolin-1 or flotillin, markers for caveolae and lipid rafts, respectively, NAGK was co-localized with these markers. These results indicate that most, if not all, of the NAGK immunopunctae represent caveolae and lipid rafts, and suggest NAGK's role in these membrane microdomains.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.21 no.1
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• pp.1-18
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• 1995

We had tested the effect of amino propane sulfonic acid(APSA) on the human skin with non-invasive technique. It was tested with four parameters that were hydration, elasticity, color and skin wrinkles. In vitro culture systems, APSA stimulated the proliferation of fibroblasts bolt it didn't stimulate that of keratinocyte. Also we obtained the similar effects in the raft culture method. So we concluded that APSA affected the dermal region than the epidermal region. In clinical tests, APSA changed the skin color, pbiomechanical properties(especially elasticity) and reduced skin wrinkles of the volunteers. And we could get the better results of skin wrinkle improvement by use of Skin Visiometer than Silflo Image analysis systems.

• Geomechanics and Engineering
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• v.18 no.4
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• pp.363-371
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• 2019

In this study, the load carrying behavior of piled rafts installed in inclined bearing rock layer was investigated for rock-mounted and -socketed conditions. It was found that settlements induced for an inclined bearing rock layer are larger than for a horizontal layer condition. The load capacity of piled rafts for the rock-mounted condition decreased as rock-layer inclination angle (${\theta}$) increased, while vice versa for the rock-socketed condition. The load capacities of raft and piles both decreased with increasing ${\theta}$ for the rock-mounted condition. When bearing rock layer was inclined, loads carried by uphill-side piles were greater than those by downhill-side piles. The values of differential settlements of rock-mounted and -socketed conditions were not significantly different whereas slightly higher for the rock-socketed condition. The values of load sharing ratio (${\alpha}_p$) and its variation with settlement were not markedly changed by the inclination of bedrock. It was shown that ${\alpha}_p$ for piled rafts installed in rock layer was not affected by ${\theta}$ whereas actual loads carried by raft and piles may vary depending on the pile installation and rock-layer inclination conditions.

• Structural Engineering and Mechanics
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• v.88 no.3
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• pp.273-285
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• 2023

This study examines how the interaction between soil and a wind turbine's supporting system affects the optimal design. The supporting system resting on an elastic soil foundation consists of a steel conical tower and a concrete circular raft foundation, and it is subjected to wind loads. The material cost of the supporting system is aimed to be minimized employing various metaheuristic optimization algorithms including teaching-learning based optimization (TLBO). To include the influence of the soil in the optimization process, modified Vlasov and Gazetas elastic soil models are integrated into the optimization algorithms using the application programing interface (API) feature of the structural analysis program providing two-way data flow. As far as the optimal designs are considered, the best minimum cost design is achieved for the TLBO algorithm, and the modified Vlasov model makes the design economical compared with the simple Gazetas and infinitely rigid soil models. Especially, the optimum design dimensions of the raft foundation extremely reduce when the Vlasov realistic soil reactions are included in the optimum analysis. Additionally, as the designated design wind speed is decreased, the beneficial impact of soil interaction on the optimum material cost diminishes.

• Journal of Adhesion and Interface
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• v.19 no.3
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• pp.106-112
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• 2018

Recently, the hyperthermia treatment of malignant tissues has gained great attention as a biocompatible and benign method that facilitates successful cancer therapy compared to radiation and chemotherapy. In this study, superparamagnetic ($Fe_3O_4$) iron oxide nanoparticles (IONP) coated with biocompatible polymer (IONP@P(MPC/FOM)) for the purpose of hyperthermia treatment were prepared and related characterization were performed. IONPs with having 15 nm diameter were first prepared by coprecipitation and followed by surface modification with 4-cyanopentanoic acid dithiobenzoate (CTP) for reversible addition-fragmentation chain transfer (RAFT) copolymerization by using 2-methacryloyloxyethyl phosphorylcholine (MPC) and fluorescein O-methacrylate (FOM) to form corona layer of P(MPC/FOM) on the surface of the IONP. Transmission electron microscopy (TEM) and dynamic light scattering (DLS) confirmed the morphology and hydrodynamic size of the IONP@P(MPC/FOM) and thermogravimetric analysis (TGA) confirmed the formation of P(MPC/FOM) corona layer, respectively. Exposing IONP dispersion to alternating magnetic field suggests that the IONP@P(MPC/FOM) aqueous dispersion with 0.2 wt.% can be used for hyperthermia treatment.

• Journal of Life Science
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• v.17 no.12
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• pp.1627-1633
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• 2007

c-Jun N-terminal kinase (JNK)-interacting protein 1 (JIP1), also known as Islet-brain 1 (IB1), is a scaffold protein that is highly expressed in neurons and pancreatic ${\beta}-cells$. In this study subcellular localization of JIP was investigated in cultured rat hippocampal neurons using an antibody that recognize all variants of JIP1, JIP-2 and JIP-3. The overall expression profile of JIP is punctate throughout soma and dendrites. Statistic analysis showed that $54.8{\pm}4.0%\;and\;94.1{\pm}4.5%$ of total JIP immunopuncta overlapped with those of excitatory postsynaptic markers SD-95 and ${\alpha}Camik$, respectively. In contrast, only $8.6{\pm}0.5%\;and\;7.3{\pm}0.5%$ of JIP clusters overlapped with those of inhibitory postsynaptic markers glycine receptor (GlyR) and gephyrin, respectively. JIP clusters overlapped or juxtaposed with SV2 but not GAD, markers for general and inhibitory nerve terminals, respectively. A substantial fraction $(29.3{\pm}1.0%)$ of flotillin immunopuncta, a marker for lipid rafts, clusters overlapped with those of JIP. In addition, JIP was highly expressed in some select ends of dendrites but minimal in axons. These data suggest important roles of JIP in excitatory postsynaptic sites, lipid rafts and dendritic ends.