• Journal of the Computational Structural Engineering Institute of Korea
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• v.32 no.6
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• pp.367-374
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• 2019

We investigate the effect of soil-structure interaction (SSI) on the response of LNG storage tanks to vertical seismic excitation depending on the type of foundation. An LNG storage tank with a diameter of 71 m on a clay layer with a thickness of 30 m upon bedrock, was selected as an example. The nonlinear behavior of the soil was considered in an equivalent linear method. Four types of foundation were considered, including shallow, piled raft, and pile foundations (surface and floating types). In addition, the effect of soil compaction within the group pile on the seismic response of the tank was investigated. KIESSI-3D, an analysis package in the frequency domain, was used to study the SSI and the stress in the outer tank was calculated. Based on an analysis of the numerical results, we arrived at three main conclusions: (1) for a shallow foundation, the vertical stress in the outer tank is less than the fixed base response due to the SSI effect; (2) for foundations supported by piles, the vertical stress can be greater than the fixed base stress due to the increase in the vertical impedance due to the piles and the decrease in radiation damping; and (3) soil compaction had a miniscule impact on the seismic response of the outer tank.

• Journal of the Korean Society of Marine Environment & Safety
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• v.25 no.4
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• pp.433-440
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• 2019

Offshore working environments such as ships, offshore oil and gas plants, and offshore wind turbines are isolated and directly exposed to rough seas, which pose high risks of safety accidents. Therefore, all workers in offshore plants should be able to cope with emergency situations and must be qualified according to relevant laws and regulations such as the International Convention on Standards of Training, Certification and Watchkeeping for Seafarers (STCW Convention) and Offshore Petroleum Industry Training Organization (OPITO) standards. In particular, marine workers should be able to perform cardiopulmonary resuscitation (CPR) in isolated locations or enclosed and confined spaces such as those in life-boats, life-rafts, rescue-boats, etc. Because the floor material is made of rubber, it may be difficult to perform chest compressions in life-rafts used to escape from emergency situations in ships or offshore plants. Chest compressions performed on life-rafts may reduce the accuracy of CPR and increase fatigue for those providing aid. To measure the accuracy and fatigue of those performing CPR in life-rafts, 15 experimenters with more than five years of experience as first aid instructors were exposed to different CPR environments in a marine safety training center equipped with an artificial wave generator. The results showed that the accuracy of CPR in the classroom was 99.6 %, but that in various life-raft environments was only 84 %. T-verification of the two sites confirmed the reduced accuracy of CPR performed on life-rafts. CPR on life-rafts should be performed in groups of two and with the use of automated chest compression devices.

• Applied Chemistry for Engineering
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• v.21 no.1
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• pp.34-39
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• 2010

Methacryloxypropyltrimethoxysilane (MPTMS) was used for the surface modification of silica nanoparticles in the toluene dispersion system for 8 h (MPSN). Then, methacryloxypropyl-modified silica nanoparticles were successfully prepared by solutioun polymerization in the ethanol solution at $60^{\circ}C$ for 14 h with adding AIBN initiator. The modification of ultra-fine particles (SiOx-PAA nanospheres) was investigated via EA, XPS, FTIR, TGA, SEM and TEM. The mean diameter of the bare silica nanoparticles, MPSN and SiOx-PAA monodisperse nanoparticles was about 25, 30 and 35 nm, respectively.

• Molecules and Cells
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• v.25 no.1
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• pp.99-104
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• 2008

Gangliosides, sialic acid-containing glycosphingolipids, are implicated in many neuronal diseases, but the precise molecular mechanisms underlying their pathological activities are poorly understood. Here we report that TLR2 participates in the initiation of ganglioside-triggered inflammatory signaling responses. Using FACS analysis and immunofluorescence microscopy, we found that gangliosides rapidly enhanced the cell surface expression of TLR2 in microglia, while reducing that of TLR4. The ganglioside-dependent increase of TLR2 expression was also observed at the messenger and protein levels. We also showed that gangliosides stimulate the interaction of TLR2 with Myd88, an adaptor for TLRs, and obtained evidence that lipid raft formation is closely associated with the ganglioside-induced activation of TLR2 and subsequent inflammatory signaling. These results collectively suggest that TLR2 contributes to the ability of gangliosides to cause inflammatory conditions in the brain.

• Proceedings of the KOSOMBE Conference
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• v.1995 no.11
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• pp.14-17
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• 1995

An in vitro construct of three dimensional artificial skin equivalent has been engineered using human cervical epithelial cells and human foreskin fibroblasts with a matrix of bovine type I collagen. Two cell lines were established from cervical uteri cancer tissues which have the HPV(human papillomavirus)18 genome. These two cell lines came from the same origin but have slight differencies in growth rate and tumorigenicity. The organotypic raft culturing of epithelial cells were accomplished at air-liquid interface. The differentiation related characteristics were examined by immunohistochemistry using monoclonal antibodies against EGFreceptor, cytokeratin 5/6/18 as proliferation markers and against filaggrin, involucrin, and cytokeratin 10/13 as differentiation marker. We have obtained the stratification and the differentiation in the artificial skin equivalent, and differentiation-related proteins were expressed more in the C3-artificial skin, and proteins of proliferation were expressed more in the C3N-artificial skin, relatively. We found that reconstituted artificial skin have the same characteristics of differentiation proteins of original tissue or cells of human body.

• International Journal of High-Rise Buildings
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• v.3 no.1
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• pp.35-48
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• 2014

In designing a 300 meter high skyscraper expected to be the tallest building in Japan, an earthquake-ridden country, we launched on the full-scale performance based design to ensure redundancy and establish new specifications using below new techniques. The following new techniques are applied because the existing techniques/materials are not enough to meet the established design criteria for the large-scale, irregularly-shaped building, and earth-conscious material saving and construction streamlining for reconstructing a station building are also required: ${\bullet}$ High strength materials: Concrete filled steel tube ("CFT") columns made of high-strength concrete and steels; ${\bullet}$ New joint system: Combination of outer diaphragm and aluminium spray jointing; ${\bullet}$ Various dampers including corrugated steel-plate walls, rotational friction dampers, oil dampers, and inverted-pendulum adaptive tuned mass damper (ATMD): Installed as appropriate; and ${\bullet}$ Foundation system: Piled raft foundation, soil cement earth-retaining wall construction, and beer bottle shaped high-strength CFT piles.

• International Journal of High-Rise Buildings
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• v.3 no.3
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• pp.167-171
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• 2014

TORANOMON HILLS is the main building of a large-scale re-development project located in the center of Tokyo. This high-rise building has a height of 247 m and 52 floors above ground, 5 floors below ground, and $62m{\times}80m$ in plan. It is used as hotel, residential facilities, offices, shops and conference facilities. The super structure is mainly a rigid steel frame with response-control devices, using concrete-filled steel tube columns. The underground section is a mixed structure composed of steel, steel-reinforced concrete and reinforced concrete framings. The piled-raft foundation type is used. The remarkable feature of this high-rise building is that the motorway runs through the basements of the building, which makes it stand just above the motorway. This condition is an important factor of the building design. The plan shape is designed to fit along the curve of the motorway. Special columns at the corners are required to avoid placing columns in the motorway. This special column is a single inclined column in the lower floors that branches into two columns in the mid-floors to suit the column location in the upper floors. The cast steel joint is used for the branching point of each special column to securely transfer the stress.

• Structural Engineering and Mechanics
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• v.4 no.3
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• pp.227-242
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• 1996

An important class of problems in the field of geotechnical engineering may be analyzed with the aid of a simple integro-differential equation. Behavior of "rigid" piles(say concrete piles), "deformable" piles(say gravel piles), pile groups, pile-raft foundations, heavily reinforced earth, flow within circular silos and down drag on cylindrical structures (for example the crusher unit of a mineral processing complex) are the type of situations that can be handled by this type of equation. The equation under consideration has the form; $$\frac{{\partial}w(r,\;z)}{{\partial}z}+f(z){\int}^z_0g({\xi})(\frac{{\partial}^2w(r,\;{\xi})}{{\partial}r^2}+\frac{1}{r}\frac{{\partial}w(r,\;{\xi})}{{\partial}r})d{\xi}+h(r,\;z)=0$$ where w(r, z) is the vertical displacement of a soil particle expressed as a function of the polar cylindrical space coordinates (r, z) and the symbols f, g and h represent soil properties and the loading conditions. The merit of the analysis is its simplicity (both in concept and in application) and the ease with which it can be expressed in a computer code. In the present paper the analysis is applied to investigate the behavior of a single rigid pile to bedrock. The emphasis, however, is placed on developing the equation, the numerical techique used in its evaluation and validation of the technique, hereafter called the ID technique, against a formal program, CRISP, which uses the FEM.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.12 no.4
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• pp.255-259
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• 1979

Depuration of extraneous substances such as bottom deposit, feces and coliforms from live oyster has been studied. Coliform accumulation of bottom cultured oysters was much higher than that of raft or long line cultured oysters. When the depuration tank designed in this study was adopted, the depuration rate could be diminished to about $50\%$ within one hour treatment. Tho most effective conditions of the tank water for depurating live oysters wer $22^{\circ}C$ in temperature, 8.80 in pH and below about 2 ppm of residual chlorine concentration.

• International Journal of High-Rise Buildings
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• v.9 no.3
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• pp.283-300
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• 2020

The Lakhta Center is a Multifunction Complex Development (MFCD) consisting of 1) an 86 story office tower rising 462 m above the ground to provide high-end offices for Gazprom Neft and Gazprom Group affiliates 2) a Multi-Function Building (MFB) that includes, a scientific/educational center, a sport center, a children's technopark, a planetarium, a multi-transformable hall, an exhibition center, shops, restaurants, and other public facilities 3) a Stylobate 4) "The Arch, which forms the main entrance to the tower, restaurants, and cafes 5) underground parking and 6) a wide range of large public plazas. While each of the MFCD buildings is technically challenging in its own right, the focus of the paper is to present the development and integration of the structural and foundation systems of the bowed, tapered, and twisted shape of the tower into the fabric of the tallest Tower in Europe.