• Title/Summary/Keyword: RAD7

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The Results of Radiation Treatment in Carcinoma of the Uterine Cervix (자궁경암의 방사선치료 성적)

  • Lee, Myung-Za;Kim, Jung-Jin
    • Radiation Oncology Journal
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    • v.3 no.2
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    • pp.95-101
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    • 1985
  • From July 1979 through March 1985,112 patients with carcinoma of the uterine cervix were treated by whole pelvis irradiation and intracavitary radiation with Cs-137. The treatment consisted of 3600rad-5200rad to the whole pelvis by parallel opposing portals, 5 days per week, 180-200rad per day. Parametrial boost with 400-800rad was given in 60 patients. 2 intracavitary Cs-137 radiation using TAO applicator were done with 7-10 days interval. Total treatment times were 40-65 days with average 52 days. Total dose of radiation to point A varied from 6820 to 10500rad with average 8388rad and to point B from 4850 to 6899ra0 with average 5898rad. All patients had follow up from 6 months to 75 months and median follow up of 31 months. $9(8\%)$ had stage $14(12.5\%)$ had stage IIa, $50(44.6\%)$ had stage IIb, $33(29.5\%)$ had stage III, $6(5.4\%)$ had stage IV. 110 patients had squamous cell carcinoma and 2 patients had adenocarcinoma. 5 year actuarial survival rates were $61.8\%$ for the entire group, $84.6\%$ for stage Ib,$77.8\%$ for stage IIa, $56.7\%$ for stage IIb, $60\%$ for stage III, $33.3\%$ for stage IV. RT dose to medial parametrium (point A) below 8000rad resulted in $7/18(38.9\%)$ failure (=death) in contrast to 25/94 $(26.5\%)$ failure with dose over 8000rad. RT dose to lateral parametrium (point B) below 6000ra0 yielded 20/63 $(34.9\%)$ failure compared to $10/49(20.4\%)$ failure with dose over 6000rad. Poor survival group of age were between 40-49 years with failure of $14/41(34.1\%)$. There was no increased failure rate below age of 40 with failure of $2111(13.9\%)$. The results suggest that survival is as good as other published data, and that higher doses over 8000rad to point A and 6000rad to point B should be delivered.

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A Biomechanical Comparative Analysis between Single-Radius and Multi-Radius Total Knee Arthroplasty for Sit-to-Stand Movement (앉았다 일어나는 동작동안 단축회전반경 무릎인공관절 수술자와 다축회전반경 무릎인공관절 수술자의 운동역학적 비교분석)

  • Jin, Young-Wan
    • Journal of Life Science
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    • v.16 no.5
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    • pp.773-779
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    • 2006
  • Eight of the individuals had a unilateral S-RAD TKA and Multi-Radius TKA ($Scorpio^{TM}$ PS, Howmedica-Osteonics, Inc.). The instrument were used Peak Motion Measurement $System^{TM}$, $MYOPAC^{TM}$EMG System, KIN-COM $III^{TM}$ System. The Figure 3 shows that the average time for the S-RAD group to accomplish the sit-to-stand movement was 1.59 s, which was 0.19 s less than the M-RAD group (p= 0.033). In Figure 5, the S-RAD TKA group tended to have $7^{\Omega}{\cdot}S^{-1}$ less trunk flexion velocity than that of the M-RAD group (p= 0.058). The Figure 6 shows that the S-RAD TKA limb tended to have less ADD displacement (p = 0.071) than that of the M-RAD TKA limb. We failed to find significant differences for ABD and ADD displacements between the S-RAD and M-RAD N-TKA limbs (p= 0.128 and 0.457, respectively). The VM of the S-RAD TKA limb demonstrated significant less RMS EMG than that of the M-RAD TKA limb from $60^{\Omega}$ to $15^{\Omega}$ of knee flexion (p 0.05). The VL of the S-RAD TKA limb also demonstrated significant less RMS EMG than that of the M-RAD TKA limb from $60^{\Omega}$ to $45^{\Omega}$ of knee flexion (p 0.05). Similar to the VM and VL, the RF of the S-RAD TKA limb showed less RMS EMG than that of the M-RAD TKA limb from $60^{\Omega}$ to $30^{\Omega}$ of knee flexion (p 0.05).

CONTINUOUS DERIVATIONS OF NONCOMMUTATIVE BANACH ALGEBRA

  • Park, Kyoo-Hong;Jung, Yong-Soo
    • Journal of applied mathematics & informatics
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    • v.7 no.1
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    • pp.319-327
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    • 2000
  • In this paper we investigate the conditions for derivations under which the Singer-Wermer theorem is true for noncommutative Banach algebra A such that either [[D(x),xD(x)] ${\in}$ rad(A) for all $x{\in}$A or $D(x)^2$x+xD(x))$^2$${\in}$rad(A) for all $x{\in}$A, where rad(A) is the Jacobson radical of A, then $D(A){\subseteq}$rad(A).

The Effect of glutathione contents of White Ginseng(WG) Extracts and Entomopathogenic Fugi Extracts on the liver in Mice that was irradiated by radiation (동충하초 추출물과 백삼추출물 투여가 방사선을 조사한 생쥐 간에서의 glutathione함량에 미치는 영향)

  • Ko, In-Ho;Yeo, Jin-Dong
    • Journal of the Korean Society of Radiology
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    • v.6 no.2
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    • pp.99-106
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    • 2012
  • The radioprotective effects of white ginseng and Entomopathogenic Fugi Extract on liver damage induced by X-ray were investigated. To one group of ICR male mice were given white ginseng(150 mg/kg/day for 7days, orally) and Entomopathogenic Fugi (200 mg/kg/day for 7days, orally) before X-ray irradiation. To another group were irradiated by 5 Gy(1.01 Gy/min) dose of X-ray. Contrast group were given with saline(0.1 ml). The levels of reduced(GSH) and oxidized(GSSG) glutathione in liver tissue were measured. The ratio of GSSG/total GSH was significantly decreased in the white ginseng and Entomopathogenic Fugi (200 mg/kg/day)(150 mg/kg/day) groups than irradiation group.

Dynamical Analysis of the Mooring Vessel System Under Surge Excitations (선박 계류시스템의 종방향 외력하의 비선형 동적거동 해석)

  • Lee, Sang-Do;You, Sam-Sang
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.24 no.2
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    • pp.140-145
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    • 2018
  • This paper deals with the dynamical analysis of a two-point mooring vessel under surge excitations. The characteristics of nonlinear behaviors are investigated completely including bifurcation and limit cycle according to particular input parameter changes. The strong nonlinearity of the mooring system is mainly caused by linear and cubic terms of restoring force. The numerical simulation is performed based on the fourth order Runge-Kutta algorithm. The bifurcation diagram and several instability phenomena are observed clearly by varying amplitudes as well as frequencies of surge excitations. Stable periodic solutions, called the periodic windows, can be obtained in succession between chaotic clouds of dots in case of frequency ${\omega}=0.4rad/s$. In addition, the chaotic region is unexpectedly increased when external forcing amplitude exceeds 1.0 with the angular frequency of ${\omega}=0.7rad/s$. Compared to the cases for ${\omega}=0.4$, 0.7rad/s, the region of chaotic behavior becomes more fragile than in the case of ${\omega}=1.0rad/s$. Finally, various types of steady states including sub-harmonic motion, limit cycle, and symmetry breaking phenomenon are observed in the two-point mooring system at each parameter value.

Characterization of HRD3, a Schizosaccharomyces pombe Gene Involved in DNA Repair and Cell Viability

  • Choi, In-Soon
    • Animal cells and systems
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    • v.7 no.2
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    • pp.159-164
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    • 2003
  • The RAD3 gene of Saccharomyces cerevisiae is required for excision repair and is essential for cell viability. The RAD3 encoded protein possesses a single stranded DNA-dependent ATPase and DNA and DNA-RNA helicase activities. To examine the extent of conservation of structure and function of a S. pombe RAD3 during eukaryotic evolution, the RAD3 homolog gene was isolated by screening of genomic DNA library. The isolated gene was designated as HRD3 (homolog of RAD3 gene). Southern blot analysis confirmed that S. pombe chromosome contains the same DNA as HRD3 gene and this gene exists as a single copy in S. pombe. The transcript of 2.8 kb was detected by Northern blot analysis, The level of transcripts increased by ultraviolet (UV) irradiation, indicating that HRD3 is one of the UV-inducible genes in S. pombe. Furthermore, the predicted partial sequence of HRD3 protein has 60% identity to S. cerevisiae RAD3 gene. This homology was particularly striking in the regions identified as being conserved in a group of DNA helicases. Gene deletion experiments indicate that the HRD3 gene is essential for viability and DNA repair function. These observations suggest evolutionary conservation of other protein components with which HRD3 might interact in mediating its DNA repair and viability functions.

The Effect of protein and lipioperoxide on White Ginseng(WG) and Fermenta Ginseng(FG) Extracts on the liver in Mice that was irradiated by radiation (방사선이 조사된 생쥐 간에서 백삼과 발효인삼추출물이 단백질 및 지질과산화에 미치는 효과)

  • Ko, In-Ho;Chang, Chae-Chul;Koh, Jeong-Sam
    • Journal of radiological science and technology
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    • v.27 no.3
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    • pp.43-50
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    • 2004
  • The effects of ginseng extracts on liver damage induced by high energy x-ray were studied. To one group of ICR male mice were given white(50 mg/kg/day for 7 days, orally) and fermenta ginseng extracts(500 mg/kg/day for 7 days, orally)before irrdiation. To another group were irradiated by 5 Gy dose of high energy x-ray. Contrast group were given with saline(0.1 ml). This study also investigated the effect between MDA, protein content and ginseng extracts on hepatic damage. This study measured the level of MDA(malondialdehyde), protein content in liver tissue. Administrating orally white (50 mg/kg/day for 7 days, orally)and fermenta ginseng extracts(500 mg/kg/day), the level of MDA were generally decreased and the inhibition was increased. And the protein contents were identical with control group. After irradiation, the protein contents were increased and MDA(malondialdehyde) was increased. Therefore, ginseng extracts increased antioxidative enzyme activity. And We know that the antioxidatant effect of extracts from white and fermenta ginseng protect radiation damage by direct antioxidant effect involving SOD, CAT, GPX. It was included that ginsengs can protect against the lipid peroxidation in radiation damage through its antioxidatant properties.

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The Effects of Korean Ginseng Components for the Mouse Irradiated 1 by Neutron(Besource) (중성자방사선에 피폭된 생쥐에 대한 인삼제제의 효과에 관하여)

  • 공태희;유성열
    • Journal of Ginseng Research
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    • v.14 no.3
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    • pp.357-363
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    • 1990
  • When mice irradiated by neutron (Be) are fed with ginseng concentrate, ginseng powder, and adaptagen of which the major ingredient is ginseng alkaloid to neutron (Be source) irradiated mouse, the following results are obtained. 1. The 50% lethal dose (LD50) for the neutron irradiation were 4 days at 600 rad, 7 days at 500 rad, 16 days at 400 rad, 33 days at 375 rad, and 55 days at 350 rad. In thistest, the standard amollntofirradiation was set at 375 rad/8 min. 2. Some spots appeared in the tail of the neutron-irradiated mouse because of blood congestion, and some had its tip tails cut. But the group administered with adaptagen did not show any of these symptoms. 3. The neutron irradiated mouse showed darkening the color of their lung-chloasmas while none of the adaptagen group had this symptom. 4. The lung tissue of the neutron irradiated mouse showed an increase of the karyolysis and cytoplasmic vacuole. 5. When both neutron irradiation and the ginseng sllbstances were given to the mouse at the same day, the 50% lethal days were increased to 29-33 days for the group administered with ginseng extract. 67 days for the group given with the ginseng powder. and 80 days for the groilp arith the adaptagen. 6. The survival rate of those fed with adaptagen for 33 days before the neutron-irradiation was 100%, while the 50% lethal daysofthe group fed with ginsengextract were 39 days and that of the group fed with ginseng powder were 69 days. 7. The serum valued of ${\gamma}$-globulin, IgG, and albumin were returned to normal condition in the group fed with adaptagen for 33 days before the neutron-irradiation. But those of the group which were given the irradiation and the ginseng substances at the same day did not show such a recovery.

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Study of Two-shaft Rotary Disc UF Module for the Separation of Oil Emulsion (2축 회전판형 UF 모듈의 Oil Emulsion 분리 특성 연구)

  • 김제우;노수홍
    • Membrane Journal
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    • v.6 no.4
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    • pp.219-226
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    • 1996
  • Rotary disc ultrafiltration module(RDM) was developed for the separation of oil emulsions. This module was devised to reduce the gel polarization phenomenon by alecoupling the operation pressure and the surface velocity of solution in ultrafiltration(UF) processes. Two-shaft engaged disc type RDM having 20 rotary disc membcanes(UOP, USA) was operated under 85kPa vacuum at $25^{\circ}$C. The pressure drop due to slip flow in the two-shaft RDM was found to be proportional to $(2.5{\omega}r)^{2}$. The pure water flux of two-shaft RDM decreased by 9.95% at the angular velocity of 41.89rad/s compared to the decrease of 3.01% for one-shaft RDM at the same velocity. When the angular velocity was changed from 31.42rad/s to 2.62rad/s, the flux decline for 1% cutting oil in two-shaft RDM was 30.16% that is similar to that of one-shaft RDM. Disc gap of 3mm and 7mm did not show any significant differences in the flux for 1% cutting oil solution. A modified model for two-shaft RDM showed good agreement with the experimental results for the cutting oil solution.

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