• Radiation Oncology Journal
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• v.5 no.1
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• pp.13-21
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• 1987

The effect of local hyperthermia of 41 to $43^{\circ}C$ for 30 minutes on radiosensitivity of normal tissue was studied utilizing jejunal crypt microcolony assay. Hyperthermia of this range enhanced the radiation effect and the effect was mainly additive without significant effect on the slopes of cell survival curves. At the isoeffect level of 20 microcolony formation, the thermal enhancement ratio was 1.02, 1.10 and 1.39 for $41^{\circ},\;42^{\circ}\;and\;43^{\circ}C$, respectively. The distribution of microcolony formation along the circumference of jejunum was not uniform, having more colonies around the mesenteric border, and this suggests the effect of uneven cooling by blood circulation.

• Toxicological Research
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• v.20 no.1
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• pp.21-29
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• 2004

We used cDNA microarray to assess gene expression profiles in hematopoetic cell line, U-937, exposed to low doses of ionizing irradiation. The 1,000 DNA elements on this array were PCR-amplified cDNAs selected from named human cancer related genes. According to the strength of irradiation, the levels of some gene expression were increased or decreased as dose-dependent manner. The gene expressions of Tubulin alpha, protein kinase, interferon-alpha, -beta, -omega receptor and ras homolog gene family H were significantly increased. Especially, Tubulin gene was shown 2.5 fold up-regulated manner under stress of 500 rad irradiation than 200 rad. On the other hand, fibroblast growth factor 12 and four and a half LIM domains, etc. were significantly down-regu-lated. Also, tumor protein 53(TP53) related genes that p53 inducible protein, tumor protein 53-binding protein looks of little significance as radiation sensitive manner. The radio-sensitivity of tubulin gene etc. that we proposed could be useful to rapid and correct survey for the bio-damage by exposure to low dose irradiation.

• Journal of The Korean Astronomical Society
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• v.48 no.5
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• pp.257-265
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• 2015

We present results of long-term multi-wavelength polarization observations of the powerful blazar 3C 279 after its γ-ray flare on 2013 December 20. We followed up this flare with single-dish polarization observations using two 21-m telescopes of the Korean VLBI Network. Observations carried out weekly from 2013 December 25 to 2015 January 11, at 22 GHz, 43 GHz, 86 GHz simultaneously, as part of the Monitoring Of GAmma-ray Bright AGN (MOGABA) program. We measured 3C 279 total flux densities of 22–34 Jy at 22 GHz, 15–28 Jy (43 GHz), and 10–21 Jy (86 GHz), showing mild variability of ≤ 50 % over the period of our observations. The spectral index between 22 GHz and 86 GHz ranged from −0.13 to −0.36. Linear polarization angles were 27°–38°, 30°–42°, and 33°–50° at 22 GHz, 43 GHz, and 86 GHz, respectively. The degree of linear polarization was in the range of 6–12 %, and slightly decreased with time at all frequencies. We investigated Faraday rotation and depolarization of the polarized emission at 22–86 GHz, and found Faraday rotation measures (RM) of −300 to −1200 rad m⁻² between 22 GHz and 43 GHz, and −800 to −5100 rad m⁻² between 43 GHz and 86 GHz. The RM values follow a power law with a mean power law index a of 2.2, implying that the polarized emission at these frequencies travels through a Faraday screen in or near the jet. We conclude that the regions emitting polarized radio emission may be different from the region responsible for the 2013 December γ-ray flare and are maintained by the dominant magnetic field perpendicular to the direction of the radio jet at milliarcsecond scales.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.22 no.2
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• pp.21-26
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• 2022

In this paper, we investigated the effect of tilting and bending of an 2.45GHz ISM band embroidered dipole array antenna due to the human body movement. The antenna characteristics showed larger variations in tilting on the X-axis than the Y-axis. The antenna gain varied by 0.25[dB] when the antenna tilted by 3.5°. As tilting angle increased the operating frequency(f_o) showed decreasing tendency and the return loss(S₁₁) showed increasing tendency. The antenna characteristics also showed more variation in bending on the X-axis than the Y-axis. As bending the antenna the antenna characteristics affected much more in bending on the X-axis than the Y-axis. The antenna gain varied by 3.73[dB] as the curvature(1/R_rad) increased by 0.04[mm^-1]. As it bended more the operating frequency(f_o) showed decreasing and then increasing tendency and the return loss(S₁₁) showed increasing tendency.

• Journal of Biosystems Engineering
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• v.9 no.1
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• pp.11-21
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• 1984

This study was intended to analyze the dynamic force system which induced the shattering of paddy grains. A model to predict the shattering of paddy grains was developed, and physical quantities, such as mass distribution and rigidity of rice plant, needed for evaluating the minimum shattering forces were also measured. Under the assumption that rice plant right before harvesting is a vibratory system, the mathematical model of the vibratory system was developed and solved with the varied conditions of forcing functions. The results of the study were summarized as follows: 1. The shattering of grain occurred at the abscission layer of grain by the bending moments resulted from the impact force due to the collision of panicles of rice plant. 2. The vibratory model developed for milyang 23 rice variety was analyzed to give the natural frequencies of 7-9 Hz, which were closely related with the excitation frequencies of 4-10 Hz caused by various machine parts besides engine. Thus, avoiding the resonance should be taken into consideration in the design of the harvesting machinery. 3. It was analyzed to predict the lowest frequency that could develop the shattering when the excitation force was applied to the lower end of stem. The lowest frequency for the Milyang 23 rice variety ranged from 8.33 Hz to 11.66 Hz as the amplitude varied from 1 cm to 2.5 cm. 4. The degree of shattering depended upon the magnitude of the impact force and its application point. For Milyang 23 rice variety, the minimum impact force developing the shattering was $5g_f$ when it was applied at 1 cm above the lower end of stern and $1g_f$ when applied at 5 cm above the lower end of stem. 5. The minimum colliding velocity of the panicle, when it was on the ground that would just develop the shattering, was given as follows, $$V=\sqrt{\frac{K_t}{m_g}{\cdot}{{\phi}^2}}$$ where V : The colliding velocity of the panicle against ground to cause the shatteering of rice grain. (cm/sec) $K_t$ : The minimum spring constant for bending at the abscission layer of grain. (dyne-cm/rad) ${\phi}$ : The minimum shattering angle of grain (rad) $m_g$ : The maximum mass of grain. (g).

• The Bulletin of The Korean Astronomical Society
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• v.41 no.1
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• pp.65.1-65.1
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• 2016

We present results of long-term multi-wavelength polarization observations of the powerful blazar 3C 279 after its ${\gamma}$-ray flare on 2013 December 20. We followed up this flare by means of single-dish polarization observations with two 21-m telescopes of the Korean VLBI Network, carried out weekly from 2013 December 25 to January 11, and at 22, 43, and 86 GHz, simultaneously. These observations were part of the Monitoring Of GAmma-ray Bright AGNs (MOGABA) program. We Measured 3C 279 total flux densities at 22, 43, and 86 GHz, showing a mild variability of a factor of ${\leq}50%$ over the period of our observations. The spectral index ranged from -0.13 to -0.36 at between 22 and 86 GHz. The degree of linear polarization was in the range of 6 ~ 12 %, and slightly decreased with time at all frequencies. We found Faraday rotation measures (RM) of -300 to $-1200rad\;m^{-2}$ between 22 and 43 GHz, and -800 to $-5100rad\;m^{-2}$ between 43 and 86 GHz. The RM values follow a power law ${\mid}RM{\mid}{\propto}{\nu}^{\alpha}$, with a mean ${\alpha}$ of 2.2, implying that the polarized emission at these frequencies travels through a Faraday screen in or near the jet. We conclude that the regions emitting polarized radio emission may be different from the region responsible for the 2013 December ${\gamma}$-ray flare, and that these regions are maintained by the dominant magnetic field perpendicular to the direction of the radio jet at milliarcsecond scales.

• The Korean Journal of Pain
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• v.27 no.2
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• pp.162-167
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• 2014

Background: Although a physician may be the nearest to the radiation source during C-arm fluoroscope-guided interventions, the radiographer is also near the fluoroscope. We prospectively investigated the radiation exposure of radiographers relative to their location. Methods: The effective dose (ED) was measured with a digital dosimeter on the radiographers' left chest and the side of the table. We observed the location of the radiographers in each procedure related to the mobile support structure of the fluoroscope (Groups A, M and P). Data about age, height, weight, sex, exposure time, radiation absorbed dose (RAD), and the ED at the radiographer's chest and the side of the table was collected. Results: There were 51 cases for Group A, 116 cases for Group M and 144 cases for Group P. No significant differences were noted in the demographic data such as age, height, weight, and male to female ratio, and exposure time, RAD and ED at the side of the table. Group P had the lowest ED ($0.5{\pm}0.8{\mu}Sv$) of all the groups (Group A, $1.6{\pm}2.3{\mu}Sv$; Group M, $1.3{\pm}1.9{\mu}Sv$; P < 0.001). The ED ratio (ED on the radiographer's chest/ED at the side of the table) of Group A was the highest, and the ED radio of Group P was the lowest of all the groups (Group A, $12.2{\pm}21.5%$; Group M, $5.7{\pm}6.5%$; Group P, $2.5{\pm}6.7%$; P < 0.001). Conclusions: Radiographers can easily reduce their radiation exposure by changing their position. Two steps behind the mobile support structure can effectively decrease the exposure of radiographers by about 80%.

• BMB Reports
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• v.47 no.6
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• pp.299-310
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• 2014

Cohesin is a multi-protein complex composed of four core subunits (SMC1A, SMC3, RAD21, and either STAG1 or STAG2) that is responsible for the cohesion of sister chromatids following DNA replication until its cleavage during mitosis thereby enabling faithful segregation of sister chromatids into two daughter cells. Recent cancer genomics analyses have discovered a high frequency of somatic mutations in the genes encoding the core cohesin subunits as well as cohesin regulatory factors (e.g. NIPBL, PDS5B, ESPL1) in a select subset of human tumors including glioblastoma, Ewing sarcoma, urothelial carcinoma, acute myeloid leukemia, and acute megakaryoblastic leukemia. Herein we review these studies including discussion of the functional significance of cohesin inactivation in tumorigenesis and potential therapeutic mechanisms to selectively target cancers harboring cohesin mutations.

• Journal of The Korean Astronomical Society
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• v.21 no.2
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• pp.133-153
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• 1988

Linear polarization has been measured for fifteen extragalactic radio sources in the field of supernova remnant S 147. These observations were made at 4885, 4835, 1665, 1515, 1465, and 1385 MHz using the Very Large Array, primarily to determine unambiguous Rotation Measures (RM) of the sources. This yields a total of 11 new RM sources. Comparisons of a sample of sources which are seen through S 147 were made with sources located farther away. The result tentatively indicates that the distribution of the rotation measure of the former population is broadened, with more than a 85% level of confidence. This constitutes evidence that there is a SNR contribution to rotation measure in sources seen through the SNR. Limits on this RM contribution are statistically at 30 < | RM | < 70 rad $m^{-2}$ with a 85% statistical level of confidence. These result imply the magnetic field in the rim of S 147 has strength 10 microguass if the electron density is $1\;cm^{-3}$.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.19 no.3
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• pp.177-182
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• 1986

The dynamic mechanical properties of milk gel were examined as function of temperature, concentrations of milk and enzyme. The real and imaginary parts of the complex rigdity G' and G' were measured at $2\%$ strain and 5 rad/s of frequency. The results showed that the rigidity of milk gel was dependent on the concentration of milk (C) in such a way that $\sqrt{G'}{\propto}C$. It was found that gel point ($t_g$) was dependent on the concentration of milk as $t_g{\propto}C$, and on the concentration of enzyme as $t_g{\propto}\;1/(E)$, The activation energy of enzymatic reaction stage and coagulation stage were $21.1{\pm}5.8\;kcal/mol$ and $26.4{\pm}1.14\;kcal/mol$, respectively.