• 제목/요약/키워드: R401A, R22

검색결과 22건 처리시간 0.038초

Propatation and Application of a New HPLC Chiral Stationary Phase Edrived from 2-Amino-1-indanolo

  • 현명호;장영수;민혜정;김도훈;엄봉호
    • Bulletin of the Korean Chemical Society
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    • 제22권4호
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    • pp.401-404
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    • 2001
  • A new chiral stationary phase (CSP) based on (1R,2S)-2-amino-1-indanol, which is expected to be conformationally rigid because of its cyclic nature, was prepared. The new CSP was applied in resolving various $N-acyl-\alpha-arylalkylamines$. The chromatographic resolution results on the new CSP were compared with those on the other CSP based on (1S,2R)-norephedrine, which is believed to be conformationally flexible. Comparison of the chromatographic resolution results on the two CSPs demonstrated that conformationally flexible analytes are resolved better on the conformationally rigid CSP while conformationally rigid analytes are resolved better on the conformationally flexible CSP. From these results it was concluded that conformational rigidity or flexibility of CSPs is the important factor for the chiral recognition.

간호대학생의 핵심역량과 간호전문직관 및 취업전략과의 관계 (Relationship between Core competencies, Nursing professionalism and Employment strategies in Nursing students)

  • 한영인
    • 한국산학기술학회논문지
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    • 제17권3호
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    • pp.144-152
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    • 2016
  • 본 연구는 간호대학생의 핵심역량과 간호전문직관 및 취업전략과의 관계를 파악하기 위한 서술적 상관관계 조사연구이다. 자료수집은 2014년 11월 1일부터 11월 28일까지 B시와 G시 소재 4년 간호대학생 107명 대상으로 구조화된 설문지로 수집하였다. 수집된 자료는 SPSS 22.0 프로그램을 사용하여 분석하였다. 연구의 평균값은 핵심역량은 3.57점, 간호전문직관 4.22점, 취업전략 3.69점이었다. 핵심역량과 간호전문직관(r=.401, p<.001), 핵심역량과 취업전략(r=.559, p<.001), 간호전문직관과 취업전략(r=.465, p<.001)는 양의(+) 상관관계이었다. 취업전략에 영향을 미치는 요인은 핵심역량(${\beta}=.43$, p<.001)와 간호전문직관(${\beta}=.28$, p=.001), 학교성적(${\beta}=-.19$, p=.011)이었으며 취업전략의 약 42%를 설명하였다(F=24,82, p<.001). 결론적으로, 간호대학생의 핵심역량은 간호전문직관과 취업전략과의 양의(+) 상관관계가 있었다. 따라서 간호대학생의 핵심역량, 간호전문직관과 취업전략을 향상시키기 위해 반복연구, 프로그램개발과 교육과정개선이 필요하다.

중년후기 성인의 건강상태, 노화불안, 사회관계망, 생성감 및 행복 (The health status, aging anxiety, social networking, generativity, and happiness of late middle-aged adults)

  • 장혜경
    • 한국간호교육학회지
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    • 제27권4호
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    • pp.392-401
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    • 2021
  • Purpose: This study was conducted to identify the relationship of health status, aging anxiety, social networking, generativity, and happiness and to investigate the main factors influencing happiness of late middle-aged adults. Methods: The study collected data from a total of 153 middle-aged men and women aged 50 to 64 years old from a consumer panel of Macromill-Embrain, the biggest online survey provider in Korea. The data were analyzed using descriptive statistics, Pearson's correlation coefficient and a stepwise multiple regression using the SPSS 22.0 program. Results: The subjects' happiness mean score was 16.17±9.29. Statistically significant differences in happiness were found according to education (F=4.38, p=.014), economic status (t=5.13, p<.001), and religion (t=2.18, p=.031). Happiness was correlated significantly with health status (r=.41, p<.001), aging anxiety (r=-.62, p<.001), family support (r=.43, p<.001), friend support (r=.36, p<.001) and generativity (r=.63, p<.001). The factors influencing happiness of late middle-aged adults were generativity (𝛽=.37, p<.001), aging anxiety (𝛽=-.35, p<.001), family support (𝛽=.20, p<.001), and economic status (𝛽=.13, p=.033). The explanatory power of the model was 58.0%. Conclusion: This study will be used as basic data when developing a nursing intervention program for successful aging by identifying factors that affect the happiness of late middle-aged adults.

소하은어의 병소로부터 Flavobcterium succinicans의 분리 및 동정 (Isolation and identification of Flavobcterium succinicans from anadromous ayu Plecoglossus altivelis)

  • 이창훈;김필연;임봉수;오덕철;강봉조
    • 한국어병학회지
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    • 제22권3호
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    • pp.401-406
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    • 2009
  • 2008년 5월 제주지역 하천에 소하하는 은어 중 일부개체가 주둥이 부식 또는 체표궤양증상을 보이면서 폐사하였다. 어류 질병원인균 중 부식증 및 체표궤양과 연관성이 높은 Flavobac-terium 속 세균의 분리를 위해 Shu-Shott medium 및 R2A medium에 주둥이 부식 및 체표궤양 부위를 도말하여 배양 하였고, Flavobacterium 속 세균의 전형적인 집락인 pale yellow colony를 분리하였다. 16S rDNA 염기서열 분석결과 Flavobacterium succinicans DSM 4002(Accession NO. AM230492)와 98.27%의 상동성을 보여 F. succinicans JMFL55로 동정하였다.

응급실 간호사의 라이프케어 증진을 위한 재직의도에 영향을 미치는 요인 (Factors Affecting the Retention Intention of the Emergency Room Nurse to Promote Life Care)

  • 정지현;박현정
    • 한국엔터테인먼트산업학회논문지
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    • 제15권4호
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    • pp.287-297
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    • 2021
  • 본 연구는 응급실 간호사의 직무스트레스, 건강상태, 건강증진행위, 재직의도의 관계를 알아보고, 재직 의도에 영향을 미치는 요인을 확인하고자 시도되었다. 연구대상은 G광역시 15개 응급실에 6개월 이상 근무하는 간호사 155명이다. 자료수집기간은 2020년 10월 15일부터 2020년 11월 3일까지 설문조사를 이용하여 이루어졌다. 연구결과, 대상자의 직무스트레스와 건강증진행위(r=-0.310, p=<.000), 직무스트레스와 재직의도(r=-0.220, p=.006), 건강상태와 건강증진행위(r=-0.448, p=<.000), 건강상태와 재직의도(r=-0.296, p=<.000)는 음의 상관관계를 나타내었고, 직무스트레스와 건강상태(r=0.368, p=<.000), 건강증진행위와 재직의도(r=0.229, p=.004)는 양의 상관관계가 있는 것으로 나타났다. 재직의도에 영향을 주는 요인은 영적 건강상태(β=-0.401, p=.000), 업무량 과중에 따른 스트레스(β=-0.184, p=.016), 피로감(β=-0.191, p=.018), 사회적 건강상태(β=0.203, p=.043)로 나타났다. 회귀모형의 설명력은 22.7%였다. 따라서 응급실 간호사의 재직의도를 높이기 위해서는 건강상태를 증진하고 업무량을 조절함으로써 직무스트레스를 감소하며, 피로를 감소할 수 있는 기관의 적극적인 관심과 중재프로그램 개발이 필요하다.

판형열교환기의 세브론각에 따른 증발 열전달특성 및 압력강하에 대한 실험적 연구 (An Experimental Study on Evaperation Heat Transfer and Pressure Drop in Plated cleat Exchangers with Different Chevron Angles)

  • 김윤호;이규정
    • 대한기계학회논문집B
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    • 제26권2호
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    • pp.269-277
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    • 2002
  • Experiments on the evaporation heat transfer and pressure drop in the brazed type plate heat exchangers were performed using refrigerants R410A and R22. To investigate the geometric effect, plate heat exchangers with the same pitch and height but different 45$^{\circ}$, 35$^{\circ}$and 20$^{\circ}$chevron angles are used. Tests were conducted fur the ranges of the mass flux of refrigerant from 13 kg/m$^2$s to 34 kg/m$^2$s, the evaporation temperatures of 15$^{\circ}C$, 1$0^{\circ}C$ and 5$^{\circ}C$, vapor quality from 0.15 to 0.95 and the heat flux from 2.5 kW/m$^2$to 8.5 kW/m$^2$. The evaporation heat transfer coefficients and pressure drops were measured. Most of flow patterns are in the chum flow regime and become close to the annular flow for increasing the mass flux and the vapor quality. The heat transfer coefficient increases with increasing the evaporation temperature at a given mass flux in all plate heat exchangers. Also, the pressure drop increases with increasing the mass flux and the quality and decreasing the evaporation temperature and the chevron angle.

가변 롤 성형 공정시 길이방향 변형률에 근거한 제품 형상 설계 기술 개발 (Development of Profile Design Method Based on Longitudinal Strain for Flexible Roll Forming Process)

  • 주병돈;한상욱;신세계로;문영훈
    • 소성∙가공
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    • 제22권7호
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    • pp.401-406
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    • 2013
  • The use of roll-formed products increases every year due to its advantages, such as high production rates, reduced tooling cost and improved quality. However, till now, it is limited to part profiles with constant cross section. In recent years, the flexible roll forming process, which allows variable cross sections of profiles by adaptive roll stands, was developed. In this study, an attempt to optimize profile design for the flexible roll forming process was performed. An equation that predicts the longitudinal strain for part geometries with variable cross-sections was proposed. The relationship between geometrical parameters and the longitudinal strain was analyzed and investigations on the optimal profile design were performed. Experiments were conducted with a lab-scale roll forming machine to validate the proposed equation. The results show that the profile design method proposed in this study is feasible and parts with variable cross sections can be successfully fabricated with the flexible roll forming process.

Effects of Restricted Feeding on Intake, Digestion, Nitrogen Balance and Metabolizable Energy in Small and Large Body Sized Sheep Breeds

  • Kamalzadeh, A.;Aouladrabiei, M.R.
    • Asian-Australasian Journal of Animal Sciences
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    • 제22권5호
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    • pp.667-673
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    • 2009
  • Ninety six intact male sheep (12 months old with mean live weight of about 35 kg) were used to assess the effects of restricted feeding on intake, digestion, nitrogen balance and metabolizable energy (ME). The animals were selected from two known Iranian small and large body size breeds: 48 Sangsari (S) and 48 Afshari (A), and were divided into two equal groups: restricted (R) and a control (C). Each group had 48 sheep (24 each breed). The experiment had a duration of 15 and 75 days adaptation and treatment periods, respectively. The animals were individually placed in metabolism cages and fed a diet based on pelleted concentrate mixture consisting of alfalfa, barley grain, cottonseed meal and barley straw. The animals in group C were fed ad libitum, while animals in group R were fed at maintenance level and maintained a relatively constant live weight. During the experiment, the average daily weight gain (ADG) of S and A animals in R group was 0.34 and -0.25 g/d (0.02 and -0.02 $g/kg^{0.75}/d$), respectively. While that of S and A animals in C group was 174.4 and 194.4 g/d (10.16 and 11.48 $g/kg^{0.75}/d$), respectively. Nitrogen (N) was determined by both measured and regression methods. Animals of R group stayed at about zero N balance (0.01 and -0.00 g $N/kg^{0.75}/d$ for S and A animals, respectively). The N retention of animals of both S and A breeds in C group were similar (0.45 and 0.46 g $N/kg^{0.75}/d$, respectively). Digestible organic matter intake (DOMI) and ME requirement for maintenance (MEm) were measured by both constant weight technique and regression method by regressing N balance on DOMI and ME intake on ADG. The measured DOMI during constant weight was 24.61 and 24.27 g $DOMI/kg^{0.75}/d$ and the calculated DOMI from regression equation was 24.24 and 24.22 g $DOMI/kg^{0.75}/d$, for S and A animals, respectively. The measured MEm was 402 and 401 kJ $ME/kg^{0.75}/d$ and the calculated MEm from regression analysis was 398 and 400 kJ $ME/kg^{0.75}/d$ for S and A breeds, respectively. There were no significant differences between both measured and regression techniques. There was no significant difference between S and A breeds for DOMI, N retention, MEm, digestibility and metabolizability values. Digestibility values for OM, GE and CP and metabolizability were significantly (p<0.05) higher in restricted feeding sheep compared with that of sheep fed ad libitum.

Usability Evaluation of Graphic User Interfaces for a Military Computer-Based Training System

  • Kim, Sungho;Lee, Soojung;Lee, Kiwon;Lee, Baekhee;Lee, Jihyung;Park, Seikwon;You, Heecheon
    • 대한인간공학회지
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    • 제34권5호
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    • pp.401-410
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    • 2015
  • Objective: The present study was to improve the graphic user interface (GUI) of a military computer-based training (CBT) system in terms of usability. Background: Existing studies have focused on usability evaluation of a particular GUI type such as sequence, hierarchy, or context type; however, few research has been conducted which identifies preferred GUI features based on a comparative analysis of different GUI types. Method: A comparative evaluation was conducted by 9 CBT design experts using a 7-point scale (1: very low, 4: neutral, and 7: very high) on hierarchy and context GUI types of a military CBT system in terms of 10 usability criteria. Then, preferred features of the hierarchy and context types being accommodated, a new GUI was developed and validated by 22 CBT users. Results: While the hierarchy type was found preferred by 1.6 times in terms of controllability to the context type, the opposite was found in terms of attractiveness, simplicity, and responsiveness by 0.6, 0.8, and 0.8 times, respectively. The proposed GUI was found superior to the hierarchy and context types in terms of accessibility and informativeness by more than 1.5 times, but inferior to the hierarchy and context type in terms of simplicity by 0.6 and 0.9 times, respectively. Conclusion: The new GUI developed by accommodating the preferred features of the hierarchy and context types improves usability in terms of accessibility and informativeness except simplicity. Application: The comparative analysis of various GUIs can be applied to develop an improved GUI in a systematic manner based on preferred features of the existing GUIs.

Anthracofibrosis의 결핵활동성 지표로서 혈청 IL-2 $sR{\alpha}$, IFN-${\gamma}$, 그리고 TBGL(tuberculous glycolipid) antibody 측정의 의의 (Evaluation of Tuberculosis Activity in Patients with Anthracofibrosis by Use of Serum Levels of IL-2 $sR{\alpha}$, IFN-${\gamma}$ and TBGL(Tuberculous Glycolipid) Antibody)

  • 정도영;차영주;이병준;정혜령;이상훈;신종욱;김재열;박인원;최병휘
    • Tuberculosis and Respiratory Diseases
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    • 제55권3호
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    • pp.250-256
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    • 2003
  • 연구배경 : 기관지내시경에서 관찰되는 anthracofibrosis가 활동성결핵과 연관이 있다는 보고가 있으나, 관찰 당시에 결핵의 활동성 여부가 확실하지 않아서 항결핵치료 시행여부를 결정하기 어려운 경우가 있다. 본 연구에서는 결핵의 활동성과 연관이 높은 IL-2 $sR{\alpha}$, IFN-${\gamma}$의 혈청 농도와 결핵의 혈청진단방법인 TBGL 항체의 농도가 anthracofibrosis 환자에서 결핵의 활동성 여부를 진단하는데 도움이 되는지를 알아보고자 하였다. 방 법 : 건강한 자원자(16명), 활동성결핵으로 진단되어 투약하기 직전의 환자(22명), 활동성결핵으로 진단되고 6개월간 항결핵제 투여를 마친 환자(13명), 그리고 anthracofibrosis 환자(15명)에서 혈청을 채취한 뒤, IL-2 $sR{\alpha}$, IFN-${\gamma}$ 그리고 TBGL 항체의 농도를 ELISA 방법으로 측정하였다. 결 과 : 건강한 자원자, 결핵치료전 환자, 결핵치료후 환자, 그리고 anthracofibrosis 환자의 IL-2 $sR{\alpha}$는 각각 $640{\pm}174$, $1,611{\pm}2,423$, $953{\pm}562$, $863{\pm}401$ pg/ml, IFN-${\gamma}$의 농도는 각각 0, $8.16{\pm}17.34$, $0.70{\pm}2.53$, $2.33{\pm}6.67$ pg/ml, 그리고 TBGL 항체 농도는 각각 $0.83{\pm}0.80$, $5.91{\pm}6.71$, $6.86{\pm}6.85$, $3.22{\pm}2.59$ U/ml였다. TBGL 항체 농도만이 건강한 자원자에서 다른 군에 비해 낮았을 뿐(p<0.05) IL-2 $sR{\alpha}$와 IFN-${\gamma}$ 농도는 네 군 사이에 차이가 없었다. Anthracofibrosis 환자 중에서 나중에 활동성 결핵으로 진단된 6명과 나머지 9명 사이에서도 상기한 지표의 농도 차이는 관찰되지 않았다. 결 론 : 1) Anthracofibrosis 환자의 40%에서 활동성 결핵이 동반되었다. 2) 혈청 IL-2 $sR{\alpha}$, IFN-${\gamma}$ 그리고 TBGL 항체 농도는 anthracofibrosis에서 결핵의 활동성 지표로 유용하지 않았다. 3) 혈청 TBGL 항체 농도는 건강한 자원자와 나머지 군 사이에 유의한 차이를 보였다.