• Title/Summary/Keyword: R.M.Schafer

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Concept of Soundscape Design and the Creative Activity Domains (사운드스케이프 디자인의 개념과 그 창조적 활동영역)

  • Han, Myung-Ho
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 2014.10a
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    • pp.425-430
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    • 2014
  • The purpose of this study is to establish a clear-cut concept and meaning of soundscape design through an inquiry into the various literatures on the ideologies, features and domains of soundscape design. Soundscape enables us to design various relationship through a sound in that it is important for interaction, namely the relations with sound, environment and people in a region. Soundscape design is an endogenous design which is participated in a large number of people of the region, and it contains various activities such as research study, environmental preservation, creation of sound environment and sound education.

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In Vitro Trypanocidal Activity of Macela (Achyrocline satureioides) Extracts against Trypanosoma evansi

  • Baldissera, Matheus D.;Oliveira, Camila B.;Zimmermann, Carine E.P.;Boligon, Aline A.;Athayde, Margareth Linde;Bolzan, Leandro P.;Vaucher, Rodrigo De A.;Santurio, Janio M.;Sagrillo, Michele R.;da Silva, Aleksandro Schafer;Monteiro, Silvia G.
    • Parasites, Hosts and Diseases
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    • v.52 no.3
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    • pp.311-315
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    • 2014
  • The aim of this study was to verify the trypanocidal effectiveness of aqueous, methanolic, and ethanolic extracts of Achyrocline satureioides against Trypanosoma evansi in vitro. A. satureioides extracts, known as macela, were used on trypomastigotes at different concentrations (1, 5, 10, 50, 100, 500, and $1,000{\mu}g/ml$) and exposure times (0, 1, 3, 6, and 9 hr). A dose-dependent effect was observed when the 3 extracts were tested. The concentrations of 1, 5, and $10{\mu}g/ml$ were not able to kill trypomastigotes until 3 hr after exposure, and the highest concentrations (500 and $1,000{\mu}g/ml$) were able to kill all trypomastigotes after 1 hr. When the time of exposure was increased up to 9 hr, the concentrations at 50 and $100{\mu}g/ml$ were 100% effective to 3 extracts. The chemical analysis of the extracts revealed the presence of flavonoids, a trypanocidal compound already described. Based on the results, we can conclude that the A. satureioides extracts exhibit trypanocidal effects.