• Korean Journal of Plant Taxonomy
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• v.47 no.3
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• pp.171-179
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• 2017

Ten species of vascular plants newly recorded in Uzbekistan are presented. The first record of Anthemis ruthenica from the northern side of the Alay range is confirmed, and the species was found for the second time in a neighborhood of Tashkent as an alien. Carduus arabicus as a native plant in Central Asia is recorded for the first time from Western Pamir-Alay. Chondrilla brevirostris, C. macrocarpa, and C. phaeocephala are from the desert and adyrs zones. Crinitaria tatarica and Crepis mira collected from Western Tien-Shan are presented, Olgaea baldschuanica first recorded on the Babatag range of mountains as a subendemic species and Erigeron andryaloides from the Hissar range are reported here as among the flora of Uzbekistan. The former Centaurea apiculata Ledeb. was accepted as a synonym of C. scabiosa L. subsp. apiculata. All records were collected in different habitats of Uzbekistan. Taxonomic remarks, pictures and distribution maps for these species are provided.

• Korean Journal of Soil Science and Fertilizer
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• v.48 no.5
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• pp.384-390
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• 2015

Remote sensing can be used to provide information about the monitoring of crop situation. This study was conducted to estimate the amount of nitrogen present in paddy fields by measuring the amount of nitrogen in hairy vetch using an UAV (Unmaned Aerial Vehicle). NDVIs (Normalized Difference Vegetation Index) were calculated using UAV images obtained from paddy fields in Seocheon on May $14^{th}$ 2015. There was strong relationship between UAV NDVI and the amount of nitrogen in hairy vetch ($R^2=0.79$). Spatial distribution maps of green manure nitrogen were generated on each paddy field using the nitrogen-vegetation index relations to help farmers determine the amount of N fertilizers added to their rice fields after the application of green manure such as hairy vetch.

• Investigative Magnetic Resonance Imaging
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• v.25 no.3
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• pp.141-155
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• 2021

Purpose: To develop a 3D magnetic resonance fingerprinting (MRF) method for application in high resolution knee cartilage PD, T₁, T₂ mapping. Materials and Methods: A novel 3D acquisition trajectory with golden-angle rotating radial in k_xy direction and interleaved echo planar imaging (EPI) acquisition in the k_z direction was implemented in the MRF framework. A centric order was applied to the interleaved EPI acquisition to reduce Nyquist ghosting artifact due to field inhomogeneity. For the reconstruction, singular value decomposition (SVD) compression method was used to accelerate reconstruction time and conjugate gradient sensitivity-encoding (CG-SENSE) was performed to overcome low SNR of the high resolution data. Phantom experiments were performed to verify the proposed method. In vivo experiments were performed on 6 healthy volunteers and 2 early osteoarthritis (OA) patients. Results: In the phantom experiments, the T₁ and T₂ values of the proposed method were in good agreement with the spin-echo references. The results from the in vivo scans showed high quality proton density (PD), T₁, T₂ map with EPI echo train length (N_ETL = 4), acceleration factor in through plane (R_z = 5), and number of radial spokes (N_spk = 4). In patients, high T₂ values (50-60 ms) were seen in all transverse, sagittal, and coronal views and the damaged cartilage regions were in agreement with the hyper-intensity regions shown on conventional turbo spin-echo (TSE) images. Conclusion: The proposed 3D MRF method can acquire high resolution (0.5 mm³) quantitative maps in practical scan time (~ 7 min and 10 sec) with full coverage of the knee (FOV: 160 × 160 × 120 mm³).

• BMB Reports
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• v.56 no.3
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• pp.190-195
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• 2023

We propose a novel blood biomarker detection method that uses miRNA super-resolution imaging to enable the early diagnosis of Alzheimer's disease (AD). Here, we report a single-molecule detection method for visualizing disease-specific miRNA in tissue from an AD mice model, and peripheral blood mononuclear cells (PBMCs) from AD patients. Using optimized Magnified Analysis of Proteome (MAPs), we confirmed that five miRNAs contribute to neurodegenerative disease in the brain hippocampi of 5XFAD and wild-type mice. We also assessed PBMCs isolated from the whole blood of AD patients and a healthy control group, and subsequently analyzed those samples using miRNA super-resolution imaging. We detected more miR-200a-3p expression in the cornu ammonis 1 and dentate gyrus regions of 3 month-old 5XFAD mice than in wild-type mice. Additionally, miRNA super-resolution imaging of blood provides AD diagnosis platform for studying miRNA regulation inside cells at the single molecule level. Our results present a potential liquid biopsy method that could improve the diagnosis of early stage AD and other diseases.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.23 no.3
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• pp.80-96
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• 2024

This study conducted over two rounds Delphi survey targeting experts in the fields of roads, transportation, automobiles, intelligent transport systems(ITS), and communications to analyze the direction of change in road design, operation, and systems in the Lv.4/4+ autonomous driving era. To construct the Delphi survey items, a basic survey was conducted. The first and second Delphi surveys targeted experts in fields closely related to autonomous driving. The results of the survey revealed an expectation that in the future, transportation operations would change focus to shared autonomous vehicle(AV) and public transportation transfers, and there would be corresponding changes in the cross-sectional configuration. Exclusive lanes for AV are expected to be introduced commencing from highways and general national roads, and there was a consensus that they should be installed in the center of the road rather than on the sides and would use the same lane width as that of the existing road. In terms of facilities for AVs, it was found that it would be necessary to expand pedestrian-vehicle separation facilities, insert communication chips into facilities for location recognition, advance precision maps, and expand roadside communication facilities.

• Journal of Environmental Science International
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• v.16 no.4
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• pp.523-532
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• 2007

This study utilized the 1/25,000 topographic map of the upper area from the Geum-ho watermark located at the middle of Geum-ho river from the National Geographic Information Institute. For the analysis, first, the influence of the size of critical area to the hydro topographic factors was examined changing grid size to $10m{\times}10m,\;30m{\times}30m\;and\;50m{\times}50m$, and the critical area for the formation of a river to $0.01km^2{\sim}0.50km^2$. It is known from the examination result of watershed morphology according to the grid size that the smaller grid size, the better resolution and accuracy. And it is found, from the analysis result of the degree of the river according to the minimum critical area for each grid size, that the grid size does not affect on the degree of the river, and the number of rivers with 2nd and higher degree does not show remarkable difference while there is big difference in the number of 1st degree rivers. From the results above, it is thought that the critical area of $0.15km^2{\sim}0.20km^2$ is appropriate for formation of a river being irrelevant to the grid size in extraction of hydro topographic parameters that are used in the runoff analysis model using topographic maps. Therefore, the GIUH model applied analysis results by use of the river level difference law proposed in this study for the explanation on the outflow response-changing characters according to the decision of a critical value of a minimum level difference river, showed that, since an ogival occurrence time and an ogival flow volume are very significant in a flood occurrence in case of not undertow facilities, the researcher could obtain a good result for the forecast of river outflow when considering a convenient application of the model and an easy acquisition of data, so it's judged that this model is proper as an algorism for the decision of a critical value of a river basin.

• Food Science and Preservation
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• v.15 no.6
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• pp.840-846
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• 2008

Microwave-assisted extraction (MAE) of grape seeds was performed under the different conditions based on a central composite design for independent variables of microwave power ($0{\sim}120\;W$), ethanol concentration ($0{\sim}100%$) and extraction time ($1{\sim}5\;min$). Response surface methodology (RSM) was used to predict the optimum extraction conditions for three dependent variables in grape seed extracts: total yield, total catechin and electron donating ability. Determination coefficients ($R^2$) of regression equations for the three dependent variables were higher than 0.9 (p < 0.01). The optimal MAE conditions to yield the maximum value of total catechin (434.16 mg%) were 122.76 W microwave power, 42.88% ethanol and 4.67 min extraction time. The superimposed contour maps for maximizing the three dependent variables indicated that the MAE condition ranges were 75150 W, 4060% ethanol and 3.55.0 min. The predicted values at the optimized conditions (6.72% total yield, 408.65 mg% total catechin, and 83.33% electron donation ability) were similar to the experimental values. The optimized MAE (112.5 W, 50% EtOH, 4.2 min) was more efficient than the conventional solvent extraction using 80% EtOH, $60^{\circ}C$ for 3h and 150 rpm.

• Korean Journal of Agricultural and Forest Meteorology
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• v.8 no.4
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• pp.250-259
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• 2006

This study looks into forest fire occurrence hazards according to the change of temperature and humidity over thirty years at interval of ten days. We used data from the forest fire inventory from 1995 to 2004 and weather data such as average temperature and relative humidity for 30 years from 1971 to 2000. These data were expressed as a database with ten-day intervals for 76 weather stations. Forest fire hazards occurred in the spring season from the end of March to the middle of April. For the first step, the primitive surface of temperature and humidity was interpolated by IDW (the standard interpolation method). These thematic maps have a 1 km by 1 km grid spacing resolution. Next, we executed a simple regression analysis after extracting forest fire frequency, temperature and humidity values from 76 weather stations. The results produced a coefficient of determination ($R^2$) ranging from 0.4 to 0.6. Moreover, the estimation of forest fire occurrence hazards during early April was very high at Gyeongbuk Interior, Chungcheong Interior and part of Gangwon. The range of temperature and humidity having an influence on forest fire occurrence was as follows: average temperature and relative humidity in early April was $9-12^{\circ}C$ and 61-65%. At the end of March, temperature was $6-10^{\circ}C$, humidity 62-67%, and temperature was $11-14^{\circ}C$ and humidity 60-67% in the middle of April.

• Analytical Science and Technology
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• v.26 no.1
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• pp.91-98
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• 2013

Interested in NOA (Naturally Occurring Asbestos), Korea as well as the USA has been making geologic maps of asbestos distributed mines and surrounding areas, restoring mines, evaluating hazard, and so on. The result can be used to improve the reliability of analysts and analysis institutions by judging the amount of asbestos and set up PLM(Polarizing Light Microscope) information by analyzing in soil. The certification value of 2 kinds of CRM(Certified Reference Material) was performed by counting total 400 points with EPA 600-R-93-116 method using by PLM. The following is the result of homogeneity and stability of 2 kinds of manufactured CRM analyzed by ANOVA (Analysis of variance) and Regression Analysis. Based on the analyzation, the results are satisfied with homogeneity and long-term stability. The analyzed certification value of CRM includes the range of minimum and maximum value of point counting result for chrysotile; low concentration-1% (range, 0.25~3.00), high concentration-4% (range, 2.25~5.50).

• Journal of the Korean Applied Science and Technology
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• v.34 no.3
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• pp.451-460
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• 2017

This study optimized the extraction of antioxidants from Gugija (Lycium chinensis Mill). To determine operational parameters, including ethanol concentration ($X_1$, 0~80%) and extraction time ($X_2$, 1~5 hr), response surface methodology was applied to monitor yield, anthocyanins, flavonoids and DPPH radical scavenging activity. Coefficients of determinations ($R^2$) of the models were range of 0.8645~0.9859 (p<0.01~0.1) in dependant parameters. Yield of Gugija extracts was maximized 23.12% in extraction conditions of 4.22 h at 8.25% ethanol. Anthocyanins was maximized 1.43 (OD in 530 nm) in extraction conditions of 3.06 h at 79.98% ethanol. Flavonoids was maximized $3,100{\mu}g/100g$ in extraction conditions of 3.37 h at 67.02% ethanol. DPPH radical scavenging activity was maximized 96.93% in extraction conditions of 1.67 h at 69.81% ethanol. Optimum extraction conditions (2.5 h extraction at 70% ethanol) were obtained by superimposing the contour maps with regard to anthocyanins, flavonoids and DPPH radical scavenging activity of Gugija. Maximum values of anthocyanins, flavonoids and DPPH radical scavenging activity in optimum extraction condition were 1.0080 (OD in 530 nm), $3,145{\mu}g/100g$, 96.96%, respectively. But values of anthocyanins, flavonoids and DPPH radical scavenging activity in water extraction condition (1 h at water) were 0.4652 (OD in 530 nm), $1,633{\mu}g/100g$, 86.98%, respectively.