• Nuclear Medicine and Molecular Imaging
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• v.42 no.4
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• pp.275-284
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• 2008

Purpose: We intended to evaluate myocardial oxygen consumption ($MVO_2)$ by applying recirculation correction and modified one-compartment model to have a reference range of $MVO_2$ in normal young population and to reveal the effect of recirculation on time-activity curve (TAC). Materials and Methods: In nine normal male volunteers with mean age of $26.3{\pm}4.0$, $MVO_2$ was estimated with 925 MBq (25mCi) of $^{11}C$-Acetate (Neuroscience Research Institute, Gachon University of Medicine and Science, Incheon, Korea) and PET/CT (Biograph 6, Siemens Medical Solution, Germany). Analysis software such as $MATLAB^{(R)}$ v7.1 (Mathworks, Inc., United States), $Excel^{(R)}$ 2007 (Microsoft, United States), and $SPSS^{(R)}$ v12.0 (Apache Software Foundation, United States) were used. Twenty three frames were of $12{\times}10$, $5{\times}60$, $3{\times}120$, $2{\times}300's$ duration, respectively. The modified one-compartmental model and the recirculation correction method were applied. Statistical analysis was performed by using Test of Normality, ANOVA and Post-Hoc (Scheffe's) analysis, and p-value less than 0.05 was considered as significant. Results: The normal reference ranges of $MVO_2$ were presented as $3.18-4.64\;{\times}\;10^{-4}\;ml/g/sec$, $1.91-3.94\;{\times}\;10^{-4}\;ml/g/sec$, $4.31-6.40\;{\times}\;10^{-4}\;ml/g/sec$, $2.84-4.53\;{\times}\;10^{-4}\;ml/g/sec$ and $3.42-5.00\;{\times}\;10^{-4}\;ml/g/sec$ in the septum, the inferior wall, the lateral wall, the anterior wall and the entire wall, respectively. In addition, it was noted that the dual exponentiality of the clearance curve is due to the recirculation effect and that the characteristic of the curve is essentially mono-exponential. Conclusion: $^{11}C$-Acetate is a radiotracer worthwhile to assess $MVO_2$. Re-circulated $^{11}C$ can influence TAC of $^{11}C$ in myocadia and so the recirculation correction must be considered when measuring $MVO_2$.

• International Journal of Highway Engineering
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• v.8 no.4 s.30
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• pp.63-74
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• 2006

It's essential to meet the expectations of drivers through reasonable road design, which makes the drivers to recognize the conditions of road sufficiently. In this case, we could say that because the roads are consistently designed, drivers can make a safe and comfortable drive. There are so many studies about the alignment design consistency methods which are previously mentioned. In this study, Firstly we categorize the studies which are concerned with the estimation of the alignment design consistency methods and then apply the method which fits for the actual condition into the practice. And we'll make a realistic method by using the data which aye collected from the National Road. The developed model in this study is the predicting model including speed($V_t$) as the variable on the upper stream 100m of the curve. This model was developed which divided to two cases in the all directions of two lanes; One case is the $R{\leq}200m$ and another case is the R>200m. In the section of the $R{\leq}200m$, this case was influenced on the road alignment(R) and($V_t$) and another section was found that is affected to the speed($V_t$) on the upper stream loom rather than the effect of road alignment(R). In the case of all directions of four lanes, however, this study is predicted divided to two sections on the 400m of R, these section have more influenced to($V_t$) than the road alignment factors. This result of the four lanes was represented to different result with the two lanes. This study will further need development of the predicting model with the higher confidence through collecting data with more the exact data, the various road alignment data and speed of the several sections on the upper stream on the curve.

• Journal of the korean academy of Pediatric Dentistry
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• v.42 no.1
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• pp.30-37
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• 2015

A new colorimetric test ($Cariview^{(R)}$) using a new type of pH indicator can reflect the acidogenic potential of plaque bacteria. The objective of this study was to evaluate the correlation between $Cariview^{(R)}$ and the caries experience (measured through the dmft index) of children, and to compare $Cariview^{(R)}$ with Dentocult $SM^{(R)}$. Having obtained informed consent, 135 children less than 6 years old participated in the study. We examined their dmft index, and performed two caries activity tests ($Cariview^{(R)}$ and Dentocult $SM^{(R)}$) according to the manufacturers' instructions. In the results, $Cariview^{(R)}$ showed a moderate correlation with the dmft index (r = 0.43, p < 0.01). $Cariview^{(R)}$ showed a sensitivity of 68.8%, a specificity of 69.2%, and an area under curve of 0.686 in the ROC curve analysis. $Cariview^{(R)}$ had a significant correlation with the children's caries experience and had a slightly better explanatory ability than Dentocult $SM^{(R)}$. Furthermore, $Cariview^{(R)}$ was convenient and easy to use on uncooperative children, and also had an educational effect with its visual colors. It is suggested that $Cariview^{(R)}$ could be used clinically to identify the children susceptible to develop caries and to establish a preventive strategy.

• Proceedings of the Korea Water Resources Association Conference
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• 2019.05a
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• pp.205-205
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• 2019

우리나라에서 강우의 시간분포를 위해 보편적으로 사용되고 있는 방법은 Huff 4분위법으로 강우의 시간적 분포특성을 나타내는 무차원 시간분포곡선을 제시한 것으로, 강우의 지속기간을 4분위로 구분하여 각 분위의 강우량 중 가장 큰 값이 속해 있는 구간을 선택하여 그 구간의 위치에 따라 분위를 정하는 방법이다. 현재 실무에서는 Huff의 분위별 곡선에 대한 회귀식은 지속기간 전반에 걸쳐 정확도가 높은 이유로 6차식을 적용하고 있으나, 통계 모델링에서 간결함의 원리에 따라 회귀식이 간결할 필요가 있으며, 통계적 유의수준에 기초하여 회귀계수를 결정하여야 하므로 유의성 검정 방법을 통한 검정결과를 비교할 필요가 있다. 따라서 본 연구에서는 다중회귀분석 방법에 따른 회귀계수 유의성 검정결과 비교를 위하여 구미지역의 무차원 누가우량 백분율을 이용한 시간분포 회귀식을 이용하여 유의성 검정 방법인 분산분석 방법(Analysis of Variance)과 변수선택 방법(Backward Selection)의 검정 결과를 도출 및 비교하였다. 통계프로그램인 프로그래밍 R을 이용하여 변수선택 방법 중 후방제거법 함수를 이용하여 최종 회귀식을 도출하고 또한 7차 회귀식을 분산분석을 이용한 후방제거법으로 회귀계수를 제거하는 방법으로 최종 회귀식을 산정하였다. 분산분석을 이용한 후방제거법의 유의성 검정결과는 프로그래밍 R을 이용한 후방제거법의 결과와 동일한 것으로 분석되었다. 일반적으로 설계강우량의 시간분포를 위한 방법으로 사용되고 있는 Huff의 4분위 방법의 시간분포 회귀식은 회귀계수의 유의성 검정이 이루어지고 있지 않으므로 본 연구결과를 통해 설계강우량 시간분포 회귀식의 유의성 검정방법 제시 및 결과도출과정을 통해 시간분포 회귀식 산정기법으로 활용할 수 있을 것으로 사료된다.

• The Journal of the Acoustical Society of Korea
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• v.39 no.2
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• pp.113-119
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• 2020

Motor noise is a major concern in order to improve perceptual feeling of car interior sound due to increased motor usage in passenger cars. The purpose of this study is to propose factors that can represent the acoustic performance of motor noise according to the change of load. To this end, at first, it is shown that power spectrum and total loudness are not fit for noise performance, and then, PN_B, partial loudness related to the brush friction component, and PN_R, partial loudness related to the torque ripple component are investigated as factors representing motor noise. The performance curve of motor noise using PN_B and PN_R is proposed to identify trends of motor noise according to the loads. The curve could be a guide for the noise control, the selection of motor, and the improvement of a system.

• The Korean Journal of Pesticide Science
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• v.19 no.4
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• pp.370-393
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• 2015

This study was conducted to compare STQ method, multi-residue method in Korean food code and QuEChERS method for validated selected and accuracy, reproducibility and efficiency. A total of 45 selected and targeted pesticides were the analyzed by GC and 5 of them were crops (apple, potato, green pepper, rice, soy bean). $R^2$ values were calculated in the standard calibration curve was over 0.990. Recovery tests were performed by three replications in two levels and the relative standard deviation of the repeated experiments was less than 30%. The average percentage of recoveries in the multi-residue method in Korean food code was 89.13%, QuEChERS method was 92.45% and STQ method was 85.28%. In addition, matrix effects in multi-residue method in Korean food code was 24.61%, QuEChERS method was 23.98% and STQ method showed 11.24%. The STQ method is easy and showed high clean-up effect in extracting the sample solution than the QuEChERS method and clean-up with C18, PLS, PSA cartridge columns. A large volume of the sample was injected in order to compensable for the problem, that occurred due to high detection limit in the analyser. When the STQ method was applied using a large volume injector, the standard calibration curve showed a higher linearity $R^2=0.990$, and method detection limit was 0.01 mg/kg. It showed an average recovery of 91.84% and the relative standard deviations of three replications repeated in two level process was less than 30% and had an average matrix effect of 17.90%.

• Analytical Science and Technology
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• v.21 no.5
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• pp.412-423
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• 2008

A procedure based on solid-phase extraction (SPE) followed by liquid chromatography-tandem mass spectrometry has been developed for the simultaneous analysis of 55 basic drugs in equine urine. The test scope covers diversified classes of drugs including some ${\beta}$-blockers, ${\beta}$-agonists, antihypotensives, CNS stimulants, sedatives, tranquilizers, antidepressants, antihypertensives and so on. LC-MS/MS separation and quantification was carried out in positive electrospray ionization and multiple reaction monitoring (MRM) mode. Four different brands of mixed mode cation exchange SPE sorbents; UCT XTRACT$^{(R)}$ XRDAH, Supelco DSC-MCAX$^{(R)}$, Varian Bond Elut Certify$^{(R)}$ and Waters Oasis$^{(R)}$ MCX were compared. The UCT XTRACT$^{(R)}$ XRDAH sorbent provided the best results in the preconcentration of samples, yielding relative recoveries higher than 80% except for terbutaline (41.3%), salbutamol (71.5%), heptaminol (70.7%), phenylpropanolamine (66.3%). Detection limits of the target drugs provided by the proposed analytical procedure were between 0.2~8.3 ng/mL.

• Transactions of the Korean Society of Mechanical Engineers
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• v.13 no.3
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• pp.472-478
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• 1989

Using the SMC(sheet moulding compound) composite material consisting of E-glass chopped strand mat and unsaturated polyester resin, three-point bending tests are carried out to evaluate the elasto-plastic fracture toughness by means of R curve. The crack extension is experimentally observed with the ink staining method. The point of stable crack growth is discussed in consideration of the load-load point displacement curve, the damage behavior of the notch vicinity, and the R-curves. The damage zone of the notch vicinity was composed of the initiation and growth of subcracks as well as those of the main crack. The point of stable crack growth can be defined as the inflection point in the R curves and its point also concurrs with the proportional limit on the load-load point displacement curve.

• Journal of Ocean Engineering and Technology
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• v.15 no.3
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• pp.63-68
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• 2001

SG-365 steel is an important material and used for manufacturing a pressure vessel which the gas piping. In this investigation, the elastic plastic fracture toughness of this material is evaluated by the an unloading compliance method according to the ATM E813-97 method on the smooth and side groove 1CT specimens. The effect of smooth and side groove is studied on the elastic plastic fracture toughness. The side grooved specimen is very useful in estimation of the $J_IC. Because it is much easier than the smooth specimen to the onset of the ductile tearing by the R curve method. Besides, it improves the accuracy of toughness values, decreases the scattering of them and tunneling and shear lip by the side groove.

• Journal of Ocean Engineering and Technology
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• v.9 no.1
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• pp.111-119
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• 1995

The elastic-plastic fracture toughness($J_{IC}$) and fracture resistance (J-R curve) of SA508-3 alloy steel used for nuclear reactor pressure vessel are investigated by using CT-type specimens. Fracture toughness tests are conducted by unloading compliance method and multiple specimen method at room temperature, -2$0^{\circ}C$ and 20$0^{\circ}C$. The apparent negative crack growth phenomenon which usually arises in partial unloading compliance test is well known. The negative crack growth phenomenon in determining J sub(IC) or J-R cure from partial unloading compliance experiments may be eliminated by the offset technique. In this study, the evaluation of $J_{IC}$ multiple specimen method recommended by the JSME gives the most reliable results by using half-size CT(similar-type) specimens.