• IE interfaces
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• v.24 no.4
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• pp.408-419
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• 2011

R&D is a foundation for new business chance and productivity improvement leading to enormous expense and a long-term multi-step process. During the R&D process, decision-makers are confused due to the various future uncertainties that influence economic and technical success of the R&D projects. For these reasons, several decision-making models for R&D project investment have been suggested; they are based on traditional methods such as Discounted Cash Flow (DCF), Decision Tree Analysis (DTA) and Real Option Analysis (ROA) or some fusion forms of the traditional methods. However, almost of the models have constraints in practical use owing to limits on application, procedural complexity and incomplete reflection of the uncertainties. In this study, to make the constraints minimized, we propose a new model named Real Option Decision Tree Model which is a conceptual combination form of ROA and DTA. With this model, it is possible for the decision-makers to simulate the project value applying the uncertainties onto the decision making nodes.

• Journal of Information Technology Services
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• v.7 no.3
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• pp.31-45
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• 2008

The number of national research and development(R&D) projects have been continually increased, and it is necessary that the efficiency of investment of R&D projects have been improved during the last two decades. also the government has improved national R&D process and supporting tools for the projects. However, it is not enough to develop a quality model to evaluate the projects systematically. Therefore, a quality model for national R&D projects need to be revised. The quality model for the projects should be based on the global standard(ISO/IEC 9126). In this paper, the authors proposed a quality model for national R&D projects and took a case study for verification of the quality model. The quality model is defined in terms of functionality, reliability, usability, efficiency, portability and maintainability. Also, the authors suggest metrics for measuring the quality of products or services. finally, The productivity and quality of national R&D projects will be improved by the quality model.

• International Area Studies Review
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• v.12 no.3
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• pp.153-169
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• 2008

This paper examines the recently empirical test for the two types of endogenous growth models, which one is more fitted to real data. We adopt the non-stationary panel data methodologies for seeking empirical implication by using productivity and R&D data in the OECD over the past two decades. The Empirical tests show that there is a robust relationship Total Factor Productivity and R&D variables implied by semi-endogenous growth model. The relationship suggested by fully endogenous growth theory, however, is sensitive to R&D variables. Therefore, the estimation results provide empirical evidence in favour of endogenous growth theory of R&D expenditure role for sustaining economic growth. The sustained Total Factor Productivity, however, is maintained by more increasing R&D inputs for overcoming diminishing return to R&D efforts.

• 한국생물공학회:학술대회논문집
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• 2003.04a
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• pp.311-314
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• 2003

Under hyperosmotic stress, rCHO cells display decreased specific growth rate $({\mu})$ and increased specific antibody productivity $(q_{Ab})$. The effects of hyperosmotic stress on batch culture cellular dynamics are not well understood. To this end, we conducted a proteome profile of rCHO cells, using 2D-gel, MALDI-TOF-MS and MS/MS. As a result, the proteome profile of rCHO cells could be established using 41 identified proteins. Based on this proteome profile of rCHO cells, we have found at least 8 differently expressed spots at hyperosmotic osmolality (450 mOsm/kg). Among these spots, two metabolic enzymes were found to be up-regulated (pyruvate kinase and GAPDH), while down-regulated protein was identified as tubulin. It shows that hyperosmotic stress can alter metabolic state, by up-regulated activities of two glycolysis enzymes, which could lead to activate the generation of metabolic energy. Tubulin expression was down-regulated, suggesting a reduction of cell division. Finally, the increased conversion energy could leads to improve overall productivity.

• Economic Analysis
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• v.17 no.1
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• pp.103-130
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• 2011

This paper intends to provide applied economists which study the effects of research and development with valuable information on econometric model selection. It includes extensive discussion on econometric models which have been applied for the study on the relationship between research and development and productivity. In particular, it compares various stochastic production frontier models which have been developed recently. The discussion decomposes them into models with scaling property and the ones with nonscaling property as well as models with monotonic and nonmonotonic relationships between research and development and productivity. Finally, this paper applies the models to two different panel data sets (firm level data and country level data) and compare estimation results from competing econometric models.

• Transactions of the Korean Society of Machine Tool Engineers
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• v.15 no.3
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• pp.1-7
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• 2006

By the reason of increased demand of high productivity, the researches on manufacturing process and equipments for reducing cycle time have been made in many directions of a machine tool industries. Especially high productivity is very important to machining center with high-speed spindle. This paper proposed method of reducing T-T(tool to tool) time which results in shorter unclamping time. T-T time varies as factors such as a hydraulic system, a drawbar mass, a flow meter, a disc spring, piston and pipe diameters. In this paper We could find design factors has much influence on decreasing the unclamping time using DOE(Design of Experiment) and optimized the level of the factors using AMESim $4.0^{(R)}$ and visualNastran $4D^{(R)}$ Finally, we have verified improved result of the optimized factors with initial design.

• International Journal of Quality Innovation
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• v.9 no.3
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• pp.123-144
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• 2008

This paper describes a comprehensive approach to examine how technological innovation contributes to the renewal of a firm's competences through its dynamic and reciprocal relationship with R&D and product commercialization. Three theories of technology and innovation (the R&D and technological knowledge concept, product-process concept, technological interdependence concept) are used to relate technology and innovation to strategic management. Based on these theories, this paper attempts to identify the dynamic relationship between product innovation and process innovation using system dynamics by investigating that aspect of the dynamic changes in the closed feedback circulation structure in which R&D investments drive the accumulation of technological knowledge. Further, such knowledge accumulation actualizes product innovation and process innovation, subsequently resulting in an increase in productivity, customer satisfaction, profit generation, and.

• Journal of Microbiology and Biotechnology
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• v.26 no.7
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• pp.1285-1289
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• 2016

A split-column photobioreactor (SC-PBR), consisting of two bubble columns with different sizes, was developed to enhance the photon utilization efficiency in an astaxanthin production process from Haematococcus lacustris. Among the two columns, only the smaller column of SC-PBR was illuminated. Astaxanthin productivities and photon efficiencies of the SC-PBRs were compared with a standard bubble-column PBR (BC-PBR). Astaxanthin productivity of SC-PBR was improved by 28%, and the photon utilization efficiencies were 28-366% higher than the original BC-PBR. The results clearly show that the effective light regime of SC-PBR could enhance the production of astaxanthin.

• Laser Solutions
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• v.11 no.3
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• pp.21-24
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• 2008

Hybrid laser welding technology is a good process to reduce a thermal distortion and increase the productivity. However, it requires a high investment and a massive modification of the fabrication line such as a gantry system, milling machine for the edge preparation, high power laser system and weld machine. Therefore the development of an economical laser welding system is a crucial point to apply this system in shipbuilding yard. In this study, a portable hybrid laser welding carriage was developed for I-butt joint without edge milling. It is expected that the carriage type system could reduce investment cost.

• Korean Management Science Review
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• v.23 no.1
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• pp.87-113
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• 2006

This paper describes a comprehensive approach to examine how technological innovation contributes to the renewal of the firm's competences through its dynamic and reciprocal relationship with R&D and product commercialization. Three theories of technology and innovation (R&D and technological knowledge concept, product-process concept, technological interdependence concept) are used to relate technology and innovation to strategic management. Based on those theories, this paper attempts to identify dynamic relationship between product innovation and process innovation by system dynamics, by investigating the aspect of the dynamic changes of the closed feedback circulation structure in which R&D investments drive technological knowledge accumulation, and such knowledge accumulation actualizes product innovation and process innovation, subsequently resulting in the increase of productivity, customer satisfaction, profit generation, and re-investment on R&D from the created profits. This provides the ability to assess the advantages and disadvantages of different technological innovation strategies and commitments, and the opportunity to explore equilibrium point and suggest a generalized technological innovation model under different industry environment parameters and time-strategies.