• Bulletin of the Korean Chemical Society
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• v.32 no.12
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• pp.4352-4360
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• 2011

A four dimensional quantitative structure activity relationship analysis was applied to a series of 50 flavonoid inhibitors of $p56^{lck}$ protein tyrosine kinase by the molecular comparative electron topological method. It was found that the -log (IC50) values of the compounds were highly dependent on the topology, size and electrostatic character of the substituents at seven positions of the flavonoid scaffold in this study. Depending on the negative or positive charge of the groups correctly embedded in these substituents, three-dimensional bio-structure to increase or decrease -log (IC50) values in the training set of 39 compounds was predicted. The test set of 11 compounds was used to evaluate the predictivity of the model. To generate 4D-QSAR model, the defined function groups and pharmacophore used as topological descriptors in the calculation of activity were of sufficient statistical quality ($R^2$ = 0.72 and $Q^2$ = 0.69). Ligand docking approach by using Dock 6.0. These compounds include many flavonoid analogs, They were docked onto human families of p56lck PTKs retrieved from the Protein Data Bank, 1lkl.pdb.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.20
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• pp.1-26
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• 1975

In order to provide basic information for the application of tissue culture to a rice breeding program. experiments were carried out on the callus formation from seedings and anthers and organ differentiation from the callus of rice varieties and their hybrids. It appeared that in general the callus tissue was more easily induced in japonicas than in indicas with significant varietal differences. A highly significant positive correlation (r=0.896$^{**}$) was obtained between the fresh weight of callus induced in NAA medium and in 2, 4-D medium in the same variety. Callus formed on the medium with 2, 4-D was more friable than that formed on the medium with NAA. The callus formation from seedlings was better than from anthers in upland rice varieties. The easiness of the callus formation appeared to be a dominant character in crosses of rice varieties. Varietal difference was also noticed in the organ differentiation from the callus and the root differentiation seemed to be easier than the shoot differentiation. Most of the plants derived from the cal1us were albinos and the frequency of occurrence of albinos was greater in callus of seedlings than in that of anthers. Greater amount of callus tissue was formed from anthers of $F_1$ plants than anyone of their parents in remote-crosses but it was clear in close-crosses. A highly significant positive correlation (r=0.504$^{**}$) was found between the callus formation from seedlings and from anthers.

• Proceedings of the Korea Technology Innovation Society Conference
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• 2006.11b
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• pp.371-396
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• 2006

To see the implication of trade policy in endogeneous growth model, we introduce trade protection that takes the form of an import tariff and represents one plus the rate of protection provided to industry sector. We showed that considering goodness of fit of regression model, we can see that the empirical evidence is strongly in favor of the character of trade policies as the instrument spurring economic growth. As for import tariff, we see that 1% increase in the rate of tariff that protect domestic market causes the rate of growth to increase by 0.87%. An import tariff to final product significantly spurs product development and faster growth come as a result. But, we should note that the effects of trade policy are muted by the induced changes in the output of intermediates in an economy that is relatively unproductive in the research lab.

• Journal of Technology Innovation
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• v.8 no.2
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• pp.119-143
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• 2000

The main objective of this study is to test hypotheses by empirical study on the technology transfer from a national institute to small and medium sized enterprises(SMEs) in the Korean electronic devices industry. The important findings of the study are as follows: First, the success of the technology transfer from national institute to SMEs depends on the character of the project manager such as research experience and academic degree level. Second, the success of the technology transfer is related to the nature of the research project, especially to the technology life cycle stage but insignificantly to the amount of R&D fund and duration. Third, another success factor for technology transfer is the joint technology development between institute and SMEs, which is due to the possibility of early commercialization of the technology development project. Fourth, the hypothesis about the relationship between the project selection and evaluation results and technology transfer success is not statistically supported.

• Journal of Environmental Science International
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• v.13 no.6
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• pp.497-503
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• 2004

In this research, we have performed a T-test to see how the relationship between dependent variable or visual point level and independent variable or visual quantity is in order to clear up the correlation between pattern of visual point and visual quantity by the constituents of a view from a different visual point level and the results are as follows: 1) In case of the character of Mt. Uam landscape of the city, Uamsan is set as a fixed point and about a direction of view(D), the north is a datum point from which the range of direction is distributed within 1800 westwardly and the visual range(R) is also within 2000m. An elevation is an average of 7.40 and the average story of the buildings is 3.85. Here the height of a story is about 4m so the average of the visual point difference is estimated at 15.4m. 2) The type of visual point is divided into the intersection group and the front of the highly used public buildings group. Double intersection types account for about 78.80%(52 spots) which forms a majority part of LCP. 3) The analysis of the difference of visual point level divided by eye level and that of the top of the buildings has been proved that there's a sharp difference resulted from t-test at 1 % significant level. The significant difference of elevation from height difference(l5.93m), however, has not been shown. 4) From the result of T-test about visual quantity by the elements of a view from a different visual point level, the visual quantity of mountain(VQM), sky(VQS), ground(VQG) is significant at about 1% each and that of building(VQB) is at about 5%. The difference in visual quantity of a mountain by the visual point level is at about 4% which can meet a marginal level of LCP necessary for evaluation of mountainscape.

• Journal of the Korean Institute of Navigation
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• v.19 no.1
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• pp.49-69
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• 1995

What is the national competitive power\ulcorner What are the determinants of national competitive advantage\ulcorner In order to find these problems, this study was initiated theoretically through the international trade theory and international managerial strategic theory. The flow of studies, in connection with these competitive advantage, come into industries competitive advantage from national competitive advantage. It is understood that the flow of studies is based on the change of paradigm about the international industry environment. Today, the international industry environment has been changed into vigorous situation with the new trade system such as globalization, UR negotiation, WTO system instead of GATT. Among these environments, all enterprises in any industries should try to enhance their benefit, income profits and develop their management strategy, because it is essential for them to keep and make a profit in order to be competitive against all other rivaling enterprises. According to researchers and the ages of history, the concept and determinants of competitive advantage have been dissimiliar as followings. 1) Theory of absolute advantage : Absolute Product Cost. 2) Theory of comparative advantage : Comparative Product Cost. 3) Theory of reciprocal demand : the Reciprocal Demand Structure. 4) Theory of Hechsher-Ohlin : Factor Endowment. 5) Paradox of Leontief : the Quality of Factor Endowment. 6) Theory of technological gap : R & D. 7) Technological gap model : The Technological Gap. 8) Theory of the product life cycle : Product Life Cycle. 9) Christensen's study : Firm's character & manager's character. 10) Monopolistic Advantage Theories : Monopolistic Advantage 11) Electic theory : Ownership, location and internalization specific advantages. 12) Theory of value chain : Cost advantage, Differentiation, Focus. However all these theories have the limit of illustration regarding today's competitive situation, the Porter's theory shows well the determinants of competitive advantage with competitive strategy. Therefore, the analysis of the competitive advantage for maritime industry should be studied by the determinants of competitive advantage of nations

• Applied Biological Chemistry
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• v.48 no.4
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• pp.394-399
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• 2005

The comparative molecular field analyses (CoMFA) models for the herbicidal activities against barnyardgrass (Echinochloa crus-galli) and rice plant (Orysa sativa L.) by the substituent (R) on the hexahydroisoindol-1-one ring in a series of new 2-(4-chloro-5-(2-chloroallyloxy)-2-fluorophenyl)-3-thioalkoxy-2,3,4,5,6,7-hexahydroisoindol-1-one derivatives were conducted and discussed for selectivity between both plants. The statistical results of the two best models (B2 & R7) showed the best predictability for the herbicidal activities based on the cross-validated value $q_2(r^2cv.=0.529{\sim}0.755)$ and none cross-validated value $({r^2}_{ncv.}=0.937{\sim}0.945)$, respectively. Based on the findings, the predictability and fitness of the model (B2) for barnyard grass was better than that of the model (R7) for rice plant. From the two models and contour maps, it is revealed that the novel selective character for herbicidal activity between the two plants depend on the electrostatic field and steric field for the substituent of ortho-positions on the S-phenyl group as R-substituent in hexahydroisoindol-1-one ring.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.45 no.6
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• pp.392-399
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• 2000

This study was carried out to investigate the physicochemical characteristics of corn silks. Pollination of corn silks was finished within three days after silking, and elongation of open pollinated corn silks was stopped, but unpollinated silks elongated until eight days after silking. Moisture contents of corn silks were about 92-94% at silking stage, but continuously decreased. these were about 70-75% at 30 days after silking. Chlorophyll b was higher than chlorophyll a in corn silks, and chlorophyll a/b ratios of four hybrids were high in this order : silage ＞ sweet ＞ super sweet ＞ waxy corn. Free sugars in corn silks were mainly fructose, glucose and maltose. Their composition rate was 55% of glucose, 42% of fructose and 4% of maltose. Water soluble solid (Brix %) contents of unpollinated corn silks were ranged from 13.7 to 16.8 Brix % and pollinated corn silks were from 12.6 to 13.7 Brix %. Phytic, oxalic, malic. shikimic, glutaric and acetic acid were detected on corn silks. Phytic, oxalic and glutaric acid were considered as a major organic acids in corn silks. Amino acids in corn silks were high in this order : waxy ＞ silage ＞ sweet ＞sweet corn. Serine, glycine and thereoine were contained more than 10%, and five amino acids such as aspartic, glutaric, arginine, alanine and proline were ranged about 5 to 8%. Methionine and cystine, amino acids containing sulfur were contained only small quantity as about 2.1% and 1.3%, respectively. Acetaldehyde, ethanol, acetone, DMS, isobutylaldehyde, cis-3-hexanol, 3-hexe-1-ol, acetate, trans-2-hexanol and pentanol were detected as the volatile components in corn silks, but acetaldehyde and DMS were major volitiles in silage corn silks, and acetaldehyde, ethanol and DMS were major volitiles in waxy corn silks. The length of corn silks was a positively correlated with organic acids (r=${0.556}^*$), and a negatively correlated with amino acids (r=${-0.514}^*$), respectively. Free sugars were positively correlated with all characteristics tested and significantly correlated with organic acid (r=TEX>${0.703}^{**}$), and flavonoids (r=TEX>${0.544}^*$). Chlorophyll was significantly correlated with flavonoid contents (r=TEX>${0.523}^*$). For this reason chlorophyll was evaluated as an indirect selection character for the high flavonoid containing varieties.

• Journal of Life Science
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• v.22 no.3
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• pp.332-339
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• 2012

Horizontal distributions and their ecotoxicological implications relating to organochlorine compounds (OCs) were determined in surface sediments sampled from the West Nakdong River. The concentrations of polychlorinated biphenyls (PCBs), dichlorodiphenyltrichloroethanes (DDTs), hexachlorocyclohexanes (HCHs), and hexachlorobenzene (HCB) in surface sediments were in the range of 0.57-3.68, 0.41-8.35, 0.63-1.65, and n.d.-0.56 ng/g, respectively. DDTs represent the major OC in the West Nakdong River. Concentrations of PCBs and DDTs correlate with the total organic carbon (PCBs: r=0.874, p<0.001, and DDTs: r=0.762, p<0.05, respectively), indicating that organic content in the sediments is one of the major factors for influencing horizontal distribution of the organochlorine compounds in this river. Examining the potential poisonous character of the surface sediments to benthic organisms according to the sediment quality guideline (SQG), set out by the Canadian Council of Ministers of the Environment (CCME) and the National Oceanic and Atmospheric Administration (NOAA), we found that the concentrations of total PCBs, p,p'-DDD, and ${\gamma}$-HCH were lower than the effects range-low (ER-L) and the probable effects level (PEL). As a result, it is considered that the effect of organochlorines in the region considered on benthic organisms is very low from the perspective of environmental toxicology. However, in terms of the Canadian SQC, p,p'-DDE, p,p'-DDT, and total DDTs, respectively, exceeded the interim sediment quality guidelines (ISQG) and the threshold effect level (TEL) in 30%, 17%, and 19%, respectively, of the sediment samples analyzed.

• Preventive Nutrition and Food Science
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• v.7 no.4
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• pp.405-410
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• 2002

Rice wine was prepared with medicinal plants or plant extracts to obtain a value added nutritious alcoholic tonics. Powders of ten medicinal plants (PTM) or aqueous extracts prepared from them (ATM) were added during the initial stage of fermentation. Aroma compounds of rice wine (control) and wines containing PTM or ATM were isolated by liquid-liquid continuous solvent extraction (LLCSE) and analyzed by gas chromatography-olfactometry and aroma extract dilution analysis (AEDA). Desirable aroma compounds: acetaldehyde (sweet, ethereal), benzaldehyde (sweet, fragrant), ethyl acetate (sweet) and ethyl octanoate (sweet, ethanolic) had the highest log$_3$-flavor dilution (FD) factors in ATM. Results of sensory evaluation demonstrated that intensities of undesirable aroma attributes, such as koji and yeasty notes in control, and raw medicinal herb notes in PTM, were lowest in wine with ATM. Wines made with ATM had the most attractive aroma attributes among the three different traditional Korean medicinal wines.