• 제목/요약/키워드: R%26D

검색결과 1,353건 처리시간 0.031초

ON THE CONVERGENCE OF FARIMA SEQUENCE TO FRACTIONAL GAUSSIAN NOISE

  • Kim, Joo-Mok
    • 충청수학회지
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    • 제26권2호
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    • pp.411-420
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    • 2013
  • We consider fractional Gussian noise and FARIMA sequence with Gaussian innovations and show that the suitably scaled distributions of the FARIMA sequences converge to fractional Gaussian noise in the sense of finite dimensional distributions. Finally, we figure out ACF function and estimate the self-similarity parameter H of FARIMA(0, $d$, 0) by using R/S method.

EXISTENCE AND UNIQUENESS RESULTS FOR SYSTEM OF FRACTIONAL DIFFERENTIAL EQUATIONS WITH INITIAL TIME DIFFERENCE

  • Nanware, J.A.;Dawkar, B.D.;Panchal, M.S.
    • Nonlinear Functional Analysis and Applications
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    • 제26권5호
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    • pp.1035-1044
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    • 2021
  • Existence and uniqueness results for solutions of system of Riemann-Liouville (R-L) fractional differential equations with initial time difference are obtained. Monotone technique is developed to obtain existence and uniqueness of solutions of system of R-L fractional differential equations with initial time difference.

Phytochemical Constituents of Phyllanthus urinaria

  • Cha, Joon Min;Park, Jong Eel;Choi, Sang Un;Lee, Kang Ro
    • Natural Product Sciences
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    • 제26권2호
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    • pp.151-157
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    • 2020
  • Extensive column chromatography separation of the MeOH extract from the aerial parts of Phyllanthus urinaria afforded seventeen compounds (1 - 17). The structures of the compounds were elucidated by physicochemical and spectroscopic methods to be 5'-β-D-glucopyranosyloxyjasmonic butyl ester (1), (+)-cucurbic acid (2), dendranthemoside B (3), boscialin 4'-O-β-D-glucoside (4), 4,5-dihydroblumenol A (5), (6R,9R)-megastigman-4-ene-9,13-diol (6), (3S,5R,6S,9R)-3,6-dihydroxy-5,6-dihydro-β-ionol (7), (6S,9R)-roseoside (8), mallophenol B (9), icariside B5 (10), corchoinoside B (11), canangaionoside (12), 5,6-epoxy-3-hydroxy-7-megastigmen-9-one (13), icariside B2 (14), (7E)-2β,3β-dihydroxy-megastigm-7-en-9-one (15), betulalbuside A (16), and loliolide (17). The compounds 1, and 3 - 16 were isolated for the first time from this plant. The absolute stereochemistry of compound 1 was newly determined. The isolated compounds were tested for cytotoxic activity against four human tumor cell lines in vitro using a Sulforhodamin B bioassay, but all the compounds showed weak cytotoxic activities.

Interaction of Cu(II)-meso-tetrakis(n-N-methylpyridiniumyl)porphyrin (n = 2,3,4) with Native and Synthetic Polynucleotides Probed by Polarized Spectroscopy

  • Lee, Mi-Jin;Lee, Gil-Jun;Lee, Dong-Jin;Kim, Seog-K.;Kim, Jong-Moon
    • Bulletin of the Korean Chemical Society
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    • 제26권11호
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    • pp.1728-1734
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    • 2005
  • The interactions of Cu(II)-meso-Tetrakis(n-N-methylpyridiniumyl)porphyrin (n = 2,3,4), respectively referred to as o-, m- and p-CuTMPyP, and DNA, poly$[d(A-T)_2]$ and poly$[d(G-C)_2]$ were investigated by circular and linear dichroism (CD and LD). In the o-CuTMPyP case, in which the rotation of the pyridinium ring is prevented, the shape of the CD spectrum when associated to DNA and poly$[d(A-T)_2]$ resembles and is characterized by a positive band at a low drug to DNA concentration ratio (R ratio) and is bisignate at a high R ratio. The former CD spectrum shape has been attributed to porphyrin that is bound monomerically outside of DNA while the latter can be attributed to those that are stacked. When o-CuTMPyP is bound to poly$[d(G-C)_2]$, the excitonic CD appeared at a relatively high R ratio. In contrast, a characteristic negative CD band in the Soret region was apparent for both m- and p-CuTMPyP when bound to DNA and poly$[d(G-C)_2]$ at the low R ratios, indicating that the porphyrin molecule intercalates. However, the DNA is bent near the intercalation site and the plane of the porphyrin molecule tilts relative to the DNA helix axis, as judged by the magnitude of the reduced LD. Various stacking patterns were identified by the shape of the CD spectrum for m- and p-CuTMPyP when bound to poly$[d(A-T)_2]$. Three species for the former complex and two for the latter complex were found which may reflect the extent of the stacking.

연구개발 수행기관 및 협력유형이 소재부품 R&D 효율성에 미치는 영향 (The effects of R&D institutions and cooperation types on R&D efficiency in the components and materials industry)

  • 천동필;우청원;조용곤;한명훈
    • 기술혁신연구
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    • 제27권3호
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    • pp.1-26
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    • 2019
  • 완제품 제조업 중심의 성장을 진행한 한국경제는 소재부품산업의 경쟁력 강화를 통한 산업고도화를 지향하고 있다. 소재부품산업은 기존 핵심산업의 경쟁력 유지 및 4차 산업혁명 시대에 요구되는 신산업의 육성 측면에서 더욱 주목받고 있다. 이러한 중요성에도 불구하고, 소재부품산업의 효율적인 R&D를 위한 연구가 매우 부족한 현황이다. 본 연구는 정부의 소재부품기술개발사업 성과 데이터를 기반으로 R&D 효율성 분석과 이에 기업규모와 협력유형이 미치는 영향에 대하여 탐색적 연구를 진행하였다. 분석결과, 전반적으로 R&D 효율성은 낮은 것으로 나타났으나, 이는 경제적 성과가 반영된 산출변수 설정에 기인한 결과로 판단한다. 중소기업이 주관기관일 경우가 대기업보다 규모 성과가 우수한 것으로 나타났으며, 산학연이 협력할 경우가 그렇지 않은 경우와 비교하여 성과가 저조한 것으로 나타났다. 본 연구의 결과는 연구개발 수행기관 및 협력유형에 따른 R&D 성과 창출에 대한 시사점을 제시하였다. 이는 국내 소재부품산업이 당면한 질적 성장을 위한 산업정책 기획, R&D 투자 및 배분 전략 수립에 도움을 줄 것으로 기대한다.