• 인터넷정보학회논문지
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• 제5권1호
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• pp.51-57
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• 2004

무선 인터넷을 이용하여 사용자들은 공간적 제약 없이 중요한 정보를 신속하게 제공 받을 수 있지만, 무선 통신의 특성상 불안전하고 시간 지연된 서비스에 대한 불편이 있다. 이를 개선하기 위한 방안으로 데이터 복제 기법이 제안되었으나, 복제 데이터를 유지하기 위한 부담을 극복할 필요가 있다. 본 논문은 이동형 환경에서의 거래 안정성과 데이터 가용성 증대를 위한 새로운 복제 데이터 관리 기법을 제안한다. 제안된 위임 정족수 합의(Proxy Quarum Consensus) 모델은 프락시를 이용하여 불안정한 상태의 다수의 모바일 사이트에 직접적인 투표를 하지 않는 대신이 미리 선출한 대표 정족 집단에 위임함으로써, 안정된 위임 투표(Proxy Voting)를 진행하는 제어 기법이다. 또한, 시뮬레이션과 성능 분석을 통하여 제안 기법이 기존의 복제 데이터 제어 기법에 비하여 처리 성능이 우수함을 검증하였다.

• Journal of Microbiology
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• 제41권3호
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• pp.175-182
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• 2003

Production of ribosomally synthesized antimicrobial peptides usually referred to as bacteriocins is an inducible trait in several gram positive bacteria, particularly in those belonging to the group of lactic acid bacteria. In many of these organisms, production of bacteriocins is inducible and induction requires secretion and extracellular accumulation of peptides that act as chemical messengers and trigger bacteriocin production. These inducer peptides are often referred to as autoinducers and are believed to permit a quorum sensing-based regulation of bacteriocin production. Notably, the peptides acting as autoinducers are dedicated peptides with or without antimicrobial activity or the bacteriocins themselves. The autoinducer-dependent induction of bacteriocin production requires histidine protein kinases and response regulator proteins of two-component signal transduction systems. The current working model for the regulation of class II bacteriocin production in lactic acid bacteria and the most relevant direct and indirect pieces of evidence supporting the model are discussed in this minireview.

• Animal Bioscience
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• 제37권2_spc호
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• pp.337-345
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• 2024

Ruminants possess a specialized four-compartment forestomach, consisting of the reticulum, rumen, omasum, and abomasum. The rumen, the primary fermentative chamber, harbours a dynamic ecosystem comprising bacteria, protozoa, fungi, archaea, and bacteriophages. These microorganisms engage in diverse ecological interactions within the rumen microbiome, primarily benefiting the host animal by deriving energy from plant material breakdown. These interactions encompass symbiosis, such as mutualism and commensalism, as well as parasitism, predation, and competition. These ecological interactions are dependent on many factors, including the production of diverse molecules, such as those involved in quorum sensing (QS). QS is a density-dependent signalling mechanism involving the release of autoinducer (AIs) compounds, when cell density increases AIs bind to receptors causing the altered expression of certain genes. These AIs are classified as mainly being N-acyl-homoserine lactones (AHL; commonly used by Gram-negative bacteria) or autoinducer-2 based systems (AI-2; used by Gram-positive and Gram-negative bacteria); although other less common AI systems exist. Most of our understanding of QS at a gene-level comes from pure culture in vitro studies using bacterial pathogens, with much being unknown on a commensal bacterial and ecosystem level, especially in the context of the rumen microbiome. A small number of studies have explored QS in the rumen using 'omic' technologies, revealing a prevalence of AI-2 QS systems among rumen bacteria. Nevertheless, the implications of these signalling systems on gene regulation, rumen ecology, and ruminant characteristics are largely uncharted territory. Metatranscriptome data tracking the colonization of perennial ryegrass by rumen microbes suggest that these chemicals may influence transitions in bacterial diversity during colonization. The likelihood of undiscovered chemicals within the rumen microbial arsenal is high, with the identified chemicals representing only the tip of the iceberg. A comprehensive grasp of rumen microbial chemical signalling is crucial for addressing the challenges of food security and climate targets.

• The Plant Pathology Journal
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• 제29권3호
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• pp.249-259
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• 2013

Burkholderia glumae causes rice grain rot and sheath rot by producing toxoflavin, the expression of which is regulated by quorum sensing (QS). The QS systems of B. glumae rely on N-octanoyl homoserine lactone, synthesized by TofI and its cognate receptor TofR, to activate the genes for toxoflavin biosynthesis and an IclR-type transcriptional regulator gene, qsmR. To understand genome-wide transcriptional profiling of QS signaling, we employed RNAseq of the wild-type B. glumae BGR1 with QS-defective mutant, BGS2 (BGR1 tofI::${\Omega}$) and QS-dependent transcriptional regulator mutant, BGS9 (BGR1 qsmR::${\Omega}$). A comparison of gene expression profiling among the wild-type BGR1 and the two mutants before and after QS onset as well as gene ontology (GO) enrichment analysis from differential expressed genes (DEGs) revealed that genes involved in motility were highly enriched in TofI-dependent DEGs, whereas genes for transport and DNA polymerase were highly enriched in QsmR-dependent DEGs. Further, a combination of pathways with these DEGs and phenotype analysis of mutants pointed to a couple of metabolic processes, which are dependent on QS in B. glumae, that were directly or indirectly related with bacterial motility. The consistency of observed bacterial phenotypes with GOs or metabolic pathways in QS-regulated genes implied that integration RNAseq with GO enrichment or pathways would be useful to study bacterial physiology and phenotypes.

• 한국지능시스템학회논문지
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• 제18권3호
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• pp.392-400
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• 2008

This paper proposes a novel optimization algorithm inspired by bacteria behavior patterns for foraging. Most bacteria can trace attractant chemical molecules for foraging. This tracing capability of bacteria called chemotaxis might be optimized for foraging because it has been evolved for few millenniums. From this observation, we developed a new optimization algorithm based on the chemotaxis of bacteria in this paper. We first define behavior and decision rules based on the behavior patterns of bacteria and then devise an optimization algorithm with these behavior and decision rules. Generally bacteria have a quorum sensing mechanism that makes it possible to effectively forage, but we leave its implementation as a further work for simplicity. Thereby, we call our algorithm a simple bacteria cooperative optimization (BCO) algorithm. Our simple BCO is tested with four function optimization problems on various' parameters of the algorithm. It was found from experiments that the simple BCO can be a good framework for optimization.

• 미생물학회지
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• 제44권2호
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• pp.85-92
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• 2008

Pseudomonas aeruginosa는 기회 감염성 병원균으로, Cystic fibrosis, 미생물 감염성 각막염,화상 부위 2차 감염 등의 다양한 질병을 초래한다. 정족수 인식(쿼럼 센싱)이라고도 알려져 있는 세포간 신호전달 기전이 이러한 감염에서 중요한 역할을 하기 때문에 P. aeruginosa의 정족수 인식 시스템들이 집중적으로 연구되어 왔다. P. aeruginosa의 정족수 인식 시스템들을 소개하는 많은 문헌들이 주로 두 개의 주요 acyl-homoserine lactone (AHL) 계열 정족수 신호물질들인 N-3-oxododecanoyl homoserine lactone (3OC12)과 N-butanoyl homoserine lactone (C4)에 초점을 맞추어 설명하고 있지만, 실제로는 몇 가지 새로운 신호물질들이 발견되어져 왔고, 그들이 P. aeruginosa의 병독성과 신호전달에 중요한 역할을 할 수 있음이 제안되어져 왔다. 그 중 하나가 PQS(Pseudomonas quinolone signal; 2-heptyl-3-hydroxy-4-quinolone)인데, 이 물질은 현재 P. aeruginosa의 잘 규명된 주요 신호물질로 인식되고 있다. 이에 더하여, 최근의 연구들은 또 다른 가능성 있는 P. aeruginosa신호물질들을 제안해 왔는데, diketopiperazines (DKPs)과 pyocyanin이 그들이다. DKPs는 환형 dipeptide로써 이를 구성하는 아미노산의 종류에 따라 다양한 구조를 가진다. P. aeruginosa의 배양액에서 검출된 몇몇 DKPs들이 기존에는 AHL에만 특이적으로 반응한다고 알려졌던 Vibrio 랸�N갸 LuxR biosensor를 활성화 시킬 수 있다는 것이 발견되어 새로운 신호물질로 제안되었다. Pyocyanin (1-hydroxy-5-methyl-phenazine)은 P. aeruginosa가 생산하는 여러 phenazine 화합물들 중의 하나로써, 특징적인 청록색을 띄는 산화-환원 활성물질이다. 이 물질도 정체 성장기 동안 일부 정족수 인식의 조절을 받는 유전자들의 발현을 증가시키는 최종 신호 인자로 최근 제안되었으며, 그 신호는 또 다른 전사 조절 인자인 SoxR에 의해 매개된다고 제안되었다. 본 논문에서는 P. aeruginosa에서 새롭게 발견, 제안되고 있는 이들 신호 전달 물질들에 대해 자세히 다루어 보기로 한다.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제11권8호
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• pp.3862-3888
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• 2017

In high diversity node situation, single-channel MAC protocols suffer from many collisions. To solve this problem, the research of multichannel MAC protocol has become a hotspot. And the cyclic quorum-based multichannel (CQM) MAC protocol outperformed others owing to its high frequency utilization. In addition, it can avoid the bottleneck that others suffered from and can be easily realized with only one transceiver. To obtain the accurate performance of CQM MAC protocol, a Markov chain model, which combines the channel hopping strategy of CQM protocol and IEEE 802.11 distributed coordination function (DCF), is proposed. The metrics (throughput and average packet transmission delay) are calculated in performance analysis, with respect to node number, packet rate, channel slot length and channel number. The results of numerical analysis show that the optimal performance of CQM protocol can be obtained in saturation bound situation. And then we obtain the saturation bound of CQM system by bird swarm algorithm (BSA). Finally, the Markov chain model and saturation bound are verified by Qualnet platform. And the simulation results show that the analytic and simulation results match very well.

• Journal of Information Processing Systems
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• 제4권3호
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• pp.103-112
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• 2008

This paper proposes a policy adjuster-driven Grid workflow management system for collaborative healthcare platform, which supports collaborative heart disease diagnosis applications. To select policies according to service level agreement of users and dynamic resource status, we devised a policy adjuster to handle workflow management polices and resource management policies using policy decision scheme. We implemented this new architecture with workflow management functions based on policy quorum based resource management system for providing poincare geometrycharacterized ECG analysis and virtual heart simulation service. To evaluate our proposed system, we executed a heart disease identification application in our system and compared the performance to that of the general workflow system and PQRM system under different types of SLA.

• 한국산학기술학회논문지
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• 제11권1호
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• pp.182-189
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• 2010

본 논문에서는 비동기적 분산시스템에서 고장 추적 장치를 이용한 상호배제의 문제를 서술하고 이러한 문제를 해결하는 가장 약한 고장 추적 장치를 결정하고자 한다. 이를 위해서 $M^*$라고 정의한 modal failure detector star 고장 추적 장치를 정의하고 $M^*$를 이용해서 상호배제 문제는 비동기적 분산 시스템에서 해결 가능함을 보인다. $M^*$는 perfect failure detector P보다 확실히 약하며 eventually perfect failure detector ◇P보다는 강한 고장추적 장치이다. 본 논문에서는 어떤 환경 안에서 이러한 문제가 해결 가능함을 보인다.