• Title/Summary/Keyword: Quantitative research

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Development of Cloud-Based Medical Image Labeling System and It's Quantitative Analysis of Sarcopenia (클라우드기반 의료영상 라벨링 시스템 개발 및 근감소증 정량 분석)

  • Lee, Chung-Sub;Lim, Dong-Wook;Kim, Ji-Eon;Noh, Si-Hyeong;Yu, Yeong-Ju;Kim, Tae-Hoon;Yoon, Kwon-Ha;Jeong, Chang-Won
    • KIPS Transactions on Computer and Communication Systems
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    • v.11 no.7
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    • pp.233-240
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    • 2022
  • Most of the recent AI researches has focused on developing AI models. However, recently, artificial intelligence research has gradually changed from model-centric to data-centric, and the importance of learning data is getting a lot of attention based on this trend. However, it takes a lot of time and effort because the preparation of learning data takes up a significant part of the entire process, and the generation of labeling data also differs depending on the purpose of development. Therefore, it is need to develop a tool with various labeling functions to solve the existing unmetneeds. In this paper, we describe a labeling system for creating precise and fast labeling data of medical images. To implement this, a semi-automatic method using Back Projection, Grabcut techniques and an automatic method predicted through a machine learning model were implemented. We not only showed the advantage of running time for the generation of labeling data of the proposed system, but also showed superiority through comparative evaluation of accuracy. In addition, by analyzing the image data set of about 1,000 patients, meaningful diagnostic indexes were presented for men and women in the diagnosis of sarcopenia.

A Study on the production of Music Content Using Artificial Intelligence Composition Program (인공지능 작곡 프로그램을 활용한 음악 콘텐츠 제작 연구)

  • Park, Dahae
    • Trans-
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    • v.13
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    • pp.35-58
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    • 2022
  • This study predicts the paradigm shift that the development of artificial intelligence technology will bring to the production of music content, and suggests that works created through collaboration between artificial intelligence and humans can have artistic value as finished products. Anyone can easily produce music content using artificial intelligence composition programs, and it has become an opportunity to inspire artists with various attempts and creative ideas. Although artificial intelligence technology provides convenience in human life and benefits a lot in the efficient aspect of work, it is difficult to escape the perception of data-based pattern music in the art field so far. Pattern music with many quantitative elements is not recognized as a complete creation due to the absence of abstract symbolism or meaning pursued by art. However, it predicts that if qualitative elements such as emotions and creativity are given to artificial intelligence music through human collaboration, it can be recognized as a complete work of art. The development of artificial intelligence technology increases access to culture and art from the public, and it can be expected that anyone can enjoy it as well as aesthetic experiences. In addition, various contents can be produced by improving individual digital literacy, and it is an opportunity to share and communicate with others. As such, artificial intelligence technology serves as a medium connecting the public with culture and art, and is narrowing the gap between humans and technology through art activities. Along with this cultural phenomenon, we predict the possibility of research on the production of artificial intelligence music contents with artistic value and the development of various convergence and complex art contents using artificial intelligence technology in the future.

The effect of local application of thymoquinone, Nigella sativa's bioactive component, on bone healing in experimental bone defects infected with Porphyromonas gingivalis

  • Batug, Ayse Yilmaz;Tomruk, Ceyda Ozcakir;Guzel Elif;Ozdemir, İlkay;Duygu, Gonca;Kutan, Esma;Ulker, Gul Merve Yalcin;Arici, Fatma Ozen
    • Journal of Periodontal and Implant Science
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    • v.52 no.3
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    • pp.206-219
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    • 2022
  • Purpose: This study was performed to evaluate the influence of local application of thymoquinone (TQ) on bone healing in experimental bone defects infected with Porphyromonas gingivalis (PG). Methods: Forty-two female rats were randomly divided into 6 groups. A bone defect was created on the right tibia of all animals. The PG, PG/collagen membrane (COL) and PG/TQ/COL groups were infected with PG. In the COL and PG/COL groups, the defects were covered with a COL; in the TQ/COL and PG/TQ/COL groups, the defects were covered with a TQ-containing COL. After 28 days, all animals were sacrificed. Quantitative measurements of new bone formation and osteoblast lining, as well as semiquantitative measurements of capillary density and tissue response, were analyzed. Furthermore, the presence of bacterial infections in defect areas was evaluated. Results: The new bone formation, osteoblast number, and capillary density were significantly higher in the TQ groups than in the control groups (P<0.001, P<0.001, and P<0.01, respectively). In a comparison between the TQ/COL group, with a TQ-containing COL (TQ/COL), and the PG-infected TQ-containing COL (PG/TQ/COL) group, the newly formed bone and capillary density were higher in the TQ/COL group (P<0.01). When the control group was compared to the PG, PG/COL, and PG/TQ/COL groups in terms of tissue response, the differences were statistically significant (P<0.001, P=0.02, and P=0.041, respectively). The intensity of the inflammatory cell reaction was higher in the PG, PG/COL, and PG/TQ/COL groups (P<0.05). Conclusions: Within the limitations of this study, the local application of a TQ-containing COL positively affected bone healing even if the bone defects were infected. The results suggest that TQ increased angiogenesis and showed promise for accelerating bone defect healing. Further research is warranted to support these findings and reach more definitive conclusions.

Quality Evaluation of Drone Image using Siemens star (Siemens star를 이용한 드론 영상의 품질 평가)

  • Lee, Jae One;Sung, Sang Min;Back, Ki Suk;Yun, Bu Yeol
    • Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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    • v.40 no.3
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    • pp.217-226
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    • 2022
  • In the view of the application of high-precision spatial information production, UAV (Umanned Aerial Vehicle)-Photogrammetry has a problem in that it lacks specific procedures and detailed regulations for quantitative quality verification methods or certification of captured images. In addition, test tools for UAV image quality assessment use only the GSD (Ground Sample Distance), not MTF (Modulation Transfer Function), which reflects image resolution and contrast at the same time. This fact makes often the quality of UAV image inferior to that of manned aerial image. We performed MTF and GSD analysis simultaneously using a siemens star to confirm the necessity of MTF analysis in UAV image quality assessment. The analyzing results of UAV images taken with different payload and sensors show that there is a big difference in σMTF values, representing image resolution and the degree of contrast, but slightly different in GSD. It concluded that the MTF analysis is a more objective and reliable analysis method than just the GSD analysis method, and high-quality drone images can only be obtained when the operator make images after judging the proper selection the sensor performance, image overlaps, and payload type. However, the results of this study are derived from analyzing only images acquired by limited sensors and imaging conditions. It is therefore expected that more objective and reliable results will be obtained if continuous research is conducted by accumulating various experimental data in related fields in the future.

Combining Conditional Generative Adversarial Network and Regression-based Calibration for Cloud Removal of Optical Imagery (광학 영상의 구름 제거를 위한 조건부 생성적 적대 신경망과 회귀 기반 보정의 결합)

  • Kwak, Geun-Ho;Park, Soyeon;Park, No-Wook
    • Korean Journal of Remote Sensing
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    • v.38 no.6_1
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    • pp.1357-1369
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    • 2022
  • Cloud removal is an essential image processing step for any task requiring time-series optical images, such as vegetation monitoring and change detection. This paper presents a two-stage cloud removal method that combines conditional generative adversarial networks (cGANs) with regression-based calibration to construct a cloud-free time-series optical image set. In the first stage, the cGANs generate initial prediction results using quantitative relationships between optical and synthetic aperture radar images. In the second stage, the relationships between the predicted results and the actual values in non-cloud areas are first quantified via random forest-based regression modeling and then used to calibrate the cGAN-based prediction results. The potential of the proposed method was evaluated from a cloud removal experiment using Sentinel-2 and COSMO-SkyMed images in the rice field cultivation area of Gimje. The cGAN model could effectively predict the reflectance values in the cloud-contaminated rice fields where severe changes in physical surface conditions happened. Moreover, the regression-based calibration in the second stage could improve the prediction accuracy, compared with a regression-based cloud removal method using a supplementary image that is temporally distant from the target image. These experimental results indicate that the proposed method can be effectively applied to restore cloud-contaminated areas when cloud-free optical images are unavailable for environmental monitoring.

A Real-time Correction of the Underestimation Noise for GK2A Daily NDVI (GK2A 일단위 NDVI의 과소추정 노이즈 실시간 보정)

  • Lee, Soo-Jin;Youn, Youjeong;Sohn, Eunha;Kim, Mija;Lee, Yangwon
    • Korean Journal of Remote Sensing
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    • v.38 no.6_1
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    • pp.1301-1314
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    • 2022
  • Normalized Difference Vegetation Index (NDVI) is utilized as an indicator to represent the vegetation condition on the land surface in various applications such as land cover, crop yield, agricultural drought, soil moisture, and forest disaster. However, satellite optical sensors for visible and infrared rays cannot see through the clouds, so the NDVI of the cloud pixel is not a valid value for the land surface. This study proposed a real-time correction of the underestimation noise for GEO-KOMPSAT-2A (GK2A) daily NDVI and made sure its feasibility through the quantitative comparisons with Moderate Resolution Imaging Spectroradiometer (MODIS) NDVI and the qualitative interpretation of time-series changes. The underestimation noise was effectively corrected by the procedures such as the time-series correction considering vegetation phenology, the outlier removal using long-term climatology, and the gap filling using rigorous statistical methods. The correlation with MODIS NDVI was higher, and the difference was lower, showing a 32.7% improvement compared to the original NDVI product. The proposed method has an extensibility for use in other satellite products with some modification.

Ginsenoside Rg1 alleviates Aβ deposition by inhibiting NADPH oxidase 2 activation in APP/PS1 mice

  • Zhang, Han;Su, Yong;Sun, Zhenghao;Chen, Ming;Han, Yuli;Li, Yan;Dong, Xianan;Ding, Shixin;Fang, Zhirui;Li, Weiping;Li, Weizu
    • Journal of Ginseng Research
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    • v.45 no.6
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    • pp.665-675
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    • 2021
  • Background: Ginsenoside Rg1 (Rg1), an active ingredient in ginseng, may be a potential agent for the treatment of Alzheimer's disease (AD). However, the protective effect of Rg1 on neurodegeneration in AD and its mechanism of action are still incompletely understood. Methods: Wild type (WT) and APP/PS1 AD mice, from 6 to 9 months old, were used in the experiment. The open field test (OFT) and Morris water maze (MWM) were used to detect behavioral changes. Neuronal damage was assessed by hematoxylin and eosin (H&E) and Nissl staining. Immunofluorescence, western blotting, and quantitative real-time polymerase chain reaction (q-PCR) were used to examine postsynaptic density 95 (PSD95) expression, amyloid beta (Aβ) deposition, Tau and phosphorylated Tau (p-Tau) expression, reactive oxygen species (ROS) production, and NAPDH oxidase 2 (NOX2) expression. Results: Rg1 treatment for 12 weeks significantly ameliorated cognitive impairments and neuronal damage and decreased the p-Tau level, amyloid precursor protein (APP) expression, and Aβ generation in APP/PS1 mice. Meanwhile, Rg1 treatment significantly decreased the ROS level and NOX2 expression in the hippocampus and cortex of APP/PS1 mice. Conclusions: Rg1 alleviates cognitive impairments, neuronal damage, and reduce Aβ deposition by inhibiting NOX2 activation in APP/PS1 mice.

Risk Factors for COVID-19 Infection Among Healthcare Workers. A First Report From a Living Systematic Review and meta-Analysis

  • Dzinamarira, Tafadzwa;Nkambule, Sphamandla Josias;Hlongwa, Mbuzeleni;Mhango, Malizgani;Iradukunda, Patrick Gad;Chitungo, Itai;Dzobo, Mathias;Mapingure, Munyaradzi Paul;Chingombe, Innocent;Mashora, Moreblessing;Madziva, Roda;Herrera, Helena;Makanda, Pelagia;Atwine, James;Mbunge, Elliot;Musuka, Godfrey;Murewanhema, Grant;Ngara, Bernard
    • Safety and Health at Work
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    • v.13 no.3
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    • pp.263-268
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    • 2022
  • Health care workers (HCWs) are more than ten times more likely to be infected with coronavirus infectious disease 2019 (COVID-19) than the general population, thus demonstrating the burden of COVID-19 among HCWs. Factors that expose HCWs to a differentially high-risk of COVID-19 acquisition are important to elucidate, enable appropriate public health interventions to mitigate against high risk and reduce adverse outcomes from the infection. We conducted a systematic review and meta-analysis to summarize and critically analyze the existing evidence on SARS-CoV-2 risk factors among HCWs. With no geographical limitation, we included studies, in any country, that reported (i) the PCR laboratory diagnosis of COVID-19 as an independent variable (ii) one or more COVID-19 risk factors among HCWs with risk estimates (relative risk, odds ratio, or hazard ratio) (iii) original, quantitative study design, and published in English or Mandarian. Our initial search resulted in 470 articles overall, however, only 10 studies met the inclusion criteria for this review. Out of the 10 studies included in the review, inadequate/lack of protective personal equipment, performing tracheal intubation, and gender were the most common risk factors of COVID-19. Based on the random effects adjusted pooled relative risk, HCWs who reported the use of protective personal equipment were 29% (95% CI: 16% to 41%) less likely to test positive for COVID-19. The study also revealed that HCWs who performed tracheal intubations were 34% (95% CI: 14% to 57%) more likely to test positive for COVID-19. Interestingly, this study showed that female HCWs are at 11% higher risk (RR 1.11 95% CI 1.01-1.21) of COVID-19 than their male counterparts. This article presents initial findings from a living systematic review and meta-analysis, therefore, did not yield many studies; however, it revealed a significant insight into better understanding COVID-19 risk factors among HCWs; insights important for devising preventive strategies that protect them from this infection.

Quantitative analysis of drought propagation probabilities combining Bayesian networks and copula function (베이지안 네트워크와 코플라 함수의 결합을 통한 가뭄전이 발생확률의 정량적 분석)

  • Shin, Ji Yae;Ryu, Jae Hee;Kwon, Hyun-Han;Kim, Tae-Woong
    • Journal of Korea Water Resources Association
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    • v.54 no.7
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    • pp.523-534
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    • 2021
  • Meteorological drought originates from a precipitation deficiency and propagates to agricultural and hydrological droughts through the hydrological cycle. Comparing with the meteorological drought, agricultural and hydrological droughts have more direct impacts on human society. Thus, understanding how meteorological drought evolves to agricultural and hydrological droughts is necessary for efficient drought preparedness and response. In this study, meteorological and hydrological droughts were defined based on the observed precipitation and the synthesized streamflow by the land surface model. The Bayesian network model was applied for probabilistic analysis of the propagation relationship between meteorological and hydrological droughts. The copula function was used to estimate the joint probability in the Bayesian network. The results indicated that the propagation probabilities from the moderate and extreme meteorological droughts were ranged from 0.41 to 0.63 and from 0.83 to 0.98, respectively. In addition, the propagation probabilities were highest in autumn (0.71 ~ 0.89) and lowest in winter (0.41 ~ 0.62). The propagation probability increases as the meteorological drought evolved from summer to autumn, and the severe hydrological drought could be prevented by appropriate mitigation during that time.

Comparison of Internal and External Frameworks for Units on Magnets in Elementary Science Textbooks First Developed by the Authorization System (검정제에 의해 최초 개발된 초등과학교과서들의 자석 단원에 대한 내외적 체제 비교)

  • Seongsoo, Jeon
    • Journal of The Korean Association For Science Education
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    • v.42 no.5
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    • pp.525-542
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    • 2022
  • The purpose of this study is to comparatively analyze the internal and external frameworks of elementary science textbooks, which first appeared as the authorization system of elementary science textbooks changed from the national government system. In order to confirm the purpose of the authorization system to support the development of diverse and creative textbooks, this study compared 7 authorized textbooks with the national textbook developed as the 'Use of Magnets' unit of the 2015 revised science curriculum. In this study, the textbook's framework was largely divided into an external framework and an internal framework for the 'Use of Magnets' unit of elementary science textbooks, and quantitative and qualitative analyses were conducted in parallel according to each subcategory. According to the research results, in the external framework of textbook units, all textbooks had the same structure: unit introduction, scientific inquiry, creative convergence, unit arrangement, and scientific reading materials. The framework in the 'Use of Magnets' unit of the 7 types of authorized textbooks was found to have some differences according to the textbook development team's interpretation of the curriculum achievement standards and many commonalities that maintained the framework in the national textbooks. In addition, the characteristics of each textbook were clearly revealed in some areas not specified in curriculum such as unit introduction activities and science reading materials, a meaningful change was also found in that the level of inquiry activity was classified and operated in response to the uniform inquiry activity operation of the existing government textbooks.