• Title/Summary/Keyword: Quantitative and Objective

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Establishing Quantitative Standards for Residual Alkaline Phosphatase in Pasteurized Milk

  • Kim, Dong-Hyeon;Chon, Jung-Whan;Lim, Jong-Soo;Kim, Hong-Seok;Kang, Il-Byeong;Jeong, Dana;Song, Kwang-Young;Kim, Hyunsook;Kim, Kwang-Yup;Seo, Kun-Ho
    • Food Science of Animal Resources
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    • v.36 no.2
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    • pp.194-197
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    • 2016
  • The alkaline phosphatase (ALP) assay is a rapid and convenient method for verifying milk pasteurization. Since colorimetric ALP assays rely on subjective visual assessments, their results are especially unreliable near the detection limits. In this study, we attempted to establish quantitative criteria for residual ALP in milk by using a more objective method based on spectrophotometric measurements. Raw milk was heat-treated for 0, 10, 20, 30, and 40 min and then subjected to ALP assays. The quantitative criteria for residual ALP in the milk was determined as 2 μg phenol/mL of milk, which is just above the ALP value of milk samples heat-treated for 30 min. These newly proposed methodology and criteria could facilitate the microbiological quality control of milk.

CT Quantitative Analysis and Its Relationship with Clinical Features for Assessing the Severity of Patients with COVID-19

  • Dong Sun;Xiang Li;Dajing Guo;Lan Wu;Ting Chen;Zheng Fang;Linli Chen;Wenbing Zeng;Ran Yang
    • Korean Journal of Radiology
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    • v.21 no.7
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    • pp.859-868
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    • 2020
  • Objective: To investigate the value of initial CT quantitative analysis of ground-glass opacity (GGO), consolidation, and total lesion volume and its relationship with clinical features for assessing the severity of coronavirus disease 2019 (COVID-19). Materials and Methods: A total of 84 patients with COVID-19 were retrospectively reviewed from January 23, 2020 to February 19, 2020. Patients were divided into two groups: severe group (n = 23) and non-severe group (n = 61). Clinical symptoms, laboratory data, and CT findings on admission were analyzed. CT quantitative parameters, including GGO, consolidation, total lesion score, percentage GGO, and percentage consolidation (both relative to total lesion volume) were calculated. Relationships between the CT findings and laboratory data were estimated. Finally, a discrimination model was established to assess the severity of COVID-19. Results: Patients in the severe group had higher baseline neutrophil percentage, increased high-sensitivity C-reactive protein (hs-CRP) and procalcitonin levels, and lower baseline lymphocyte count and lymphocyte percentage (p < 0.001). The severe group also had higher GGO score (p < 0.001), consolidation score (p < 0.001), total lesion score (p < 0.001), and percentage consolidation (p = 0.002), but had a lower percentage GGO (p = 0.008). These CT quantitative parameters were significantly correlated with laboratory inflammatory marker levels, including neutrophil percentage, lymphocyte count, lymphocyte percentage, hs-CRP level, and procalcitonin level (p < 0.05). The total lesion score demonstrated the best performance when the data cut-off was 8.2%. Furthermore, the area under the curve, sensitivity, and specificity were 93.8% (confidence interval [CI]: 86.8-100%), 91.3% (CI: 69.6-100%), and 91.8% (CI: 23.0-98.4%), respectively. Conclusion: CT quantitative parameters showed strong correlations with laboratory inflammatory markers, suggesting that CT quantitative analysis might be an effective and important method for assessing the severity of COVID-19, and may provide additional guidance for planning clinical treatment strategies.

A Study on the Estimation Method for the Equipment Operating Costs in the Data Center Outsourcing Environment (데이터 센터 Outsourcing에 있어서 기기 운영비요의 산정 방법에 관한 연구)

  • Hwang, Kyung-Tae;Kwon, Oh-Hun
    • The Transactions of the Korea Information Processing Society
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    • v.4 no.6
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    • pp.1401-1417
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    • 1997
  • The major objective of this study is to propose an estimation method for the equipment operating cost in the data center outsourcing situation. To accomplish the objective, the fundamental concepts about the outsourcing pricing is first established by analyzing the previous research in this area. Then an actual case of data center outsourcing is evaluated. Based on the conceptual model and the actual case, a new method is proposed. Validity of the proposed method is verified by the quantitative comparison with the previous method. Reasonability and usefulness of the method were evaluated through the customer survey.

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Free spans monitoring of subsea pipelines

  • Elshafey, Ahmed A.;Haddara, M.R.;Marzouk, H.
    • Ocean Systems Engineering
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    • v.1 no.1
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    • pp.59-72
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    • 2011
  • The objective of this work is to investigate the possibility of using the longitudinal strain on the surface of a pipe to determine the inception of dangerous free spanning. The long term objective is to develop an online monitoring technique to detect the development of dangerous free spanning in subsea pipelines. This work involves experimental study as well as finite element modeling. In the experiments, the strains at four points on a cross section of a pipeline inside the free span zone are measured. Pipes with different boundary conditions and different diameter to length ratios were tested. The pipe is treated as a simple beam with fixed-fixed or simply supported boundary conditions. The variation of the strains as a function of the diameter to length ratio gives a pointer to the inception of dangerous free spanning. The finite element results agree qualitatively with the experiments. The quantitative discrepancy is a result of the difficulty to replicate the exact boundary conditions that is used by the finite element program.

Design Exploration of High-Lift Airfoil Using Kriging Model and Data Mining Technique

  • Kanazaki, Masahiro;Yamamoto, Kazuomi;Tanaka, Kentaro;Jeong, Shin-Kyu
    • International Journal of Aeronautical and Space Sciences
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    • v.8 no.2
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    • pp.28-36
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    • 2007
  • A multi-objective design exploration for a three-element airfoil consisted of a slat, a main wing, and a flap was carried out. The lift curve improvement is important to design high-lift system, thus design has to be performed with considered multi-angle. The objective functions considered here are to maximize the lift coefficient at landing and near stall conditions simultaneously. Kriging surrogate model which was constructed based on several sample designs is introduced. The solution space was explored based on the maximization of Expected Improvement (EI) value corresponding to objective functions on the Krigingmodels. The improvement of the model and the exploration of the optimum can be advanced at the same time by maximizing EI value. In this study, a total of 90 sample points are evaluated using the Reynolds averaged Navier-Stokes simulation(RANS) for the construction of the Kriging model. In order to obtain the information of the design space, two data mining techniques are applied to design result. One is functional Analysis of Variance(ANOVA) which can show quantitative information and the other is Self-Organizing Map(SOM) which can show qualitative information.

Comparative Evaluation between Cool Roof and Green Roof in terms of Installation Cost: a Case Study of KNU Campus (설비 투자비용의 관점에서 쿨루프와 옥상녹화의 비교 평가: 경북대학교 캠퍼스 사례를 중심으로)

  • Kim, Jun-Woo;Um, Jung-Sup
    • Journal of Environmental Impact Assessment
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    • v.21 no.6
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    • pp.927-939
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    • 2012
  • Cool roofs are currently being emerged as one of important mechanism to save energy in relation to the building. Although green roof has already gained nation-wide recognition as a typical method of energy saving in the roof, this approach did not provide a realistic evidence that is economically feasible in terms of installation cost. This research is primarily intended to compare installation cost between the two techniques. This research proposes a comparative evaluation framework in a more objective and quantitative way for an installation cost between the two techniques. Kyungpook National University (KNU) was selected as a survey objective and an exhaustive and realistic comparison of installation cost between the two techniques was conducted, based on Life Cycle Cost analysis (initial investment cost, maintenance cost, dismantling and waste disposal expense). It was possible to identify that installation cost of cool roofs is 4.7 times cheaper than that of green roof. Also present value based on probabilistic approach was identified as 0.25 (4.95) higher than the installation cost on the assumption of constant price and interest. It is expected that much more installation cost for the large scale green roof will be required since small-size green roof selected as a survey objective in this study could be operated under less initial installation and maintenance condition.

A Study on Evaluation Criteria for quantitatively OSS Selection (정량적인 OSS 선정을 위한 평가지표 연구)

  • Lee, Hoo-Jae;Kim, Doo-Yeon;Choi, Il-Woo
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.13 no.4
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    • pp.1863-1871
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    • 2012
  • Utilization of the former OSS was mainly focused on the usage of system applications such as operating system and DBMS. However, nowadays many companies are trying to make use of OSS based on the application rather than the system software. However, selection of base OSS is the most important to develop of application for utilizing OSS. The scope of existing OSS evaluation studies is covered the entire OSS quality. Thus existing studies of evaluation of OSS selection is insufficient. Also, the result of assessment is based on qualitative measurement rather than quantitative ones. In this paper, we derives only the indicators for selection among the existing OSS assessment indicators and suggests the assessment indicator that is capable of quantitative assessment in accordance with the characteristics of the project. The proposed assessment indicator is divided into an initial assessment indicator that can be assessed with only the information within the OSS community, and the detailed assessment indicator through metrics to make quantitative measurements possible. In this way, an objective basis can be provided through quantitative scores & indicators when selecting OSS.

Quantitative microbial risk assessment of Campylobacter jejuni in jerky in Korea

  • Ha, Jimyeong;Lee, Heeyoung;Kim, Sejeong;Lee, Jeeyeon;Lee, Soomin;Choi, Yukyung;Oh, Hyemin;Yoon, Yohan
    • Asian-Australasian Journal of Animal Sciences
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    • v.32 no.2
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    • pp.274-281
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    • 2019
  • Objective: The objective of this study was to estimate the risk of Campylobacter jejuni (C. jejuni) infection from various jerky products in Korea. Methods: For the exposure assessment, the prevalence and predictive models of C. jejuni in the jerky and the temperature and time of the distribution and storage were investigated. In addition, the consumption amounts and frequencies of the products were also investigated. The data for C. jejuni for the prevalence, distribution temperature, distribution time, consumption amount, and consumption frequency were fitted with the @RISK fitting program to obtain appropriate probabilistic distributions. Subsequently, the dose-response models for Campylobacter were researched in the literature. Eventually, the distributions, predictive model, and dose-response model were used to make a simulation model with @RISK to estimate the risk of C. jejuni foodborne illness from the intake of jerky. Results: Among 275 jerky samples, there were no C. jejuni positive samples, and thus, the initial contamination level was statistically predicted with the RiskUniform distribution [RiskUniform (-2, 0.48)]. To describe the changes in the C. jejuni cell counts during distribution and storage, the developed predictive models with the Weibull model (primary model) and polynomial model (secondary model) were utilized. The appropriate probabilistic distribution was the BetaGeneral distribution, and it showed that the average jerky consumption was 51.83 g/d with a frequency of 0.61%. The developed simulation model from this data series and the dose-response model (Beta Poisson model) showed that the risk of C. jejuni foodborne illness per day per person from jerky consumption was $1.56{\times}10^{-12}$. Conclusion: This result suggests that the risk of C. jejuni in jerky could be considered low in Korea.

Genetic factors influencing milk and fat yields in tropically adapted dairy cattle: insights from quantitative trait loci analysis and gene associations

  • Thawee Laodim;Skorn Koonawootrittriron;Mauricio A. Elzo;Thanathip Suwanasopee;Danai Jattawa;Mattaneeya Sarakul
    • Animal Bioscience
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    • v.37 no.4
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    • pp.576-590
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    • 2024
  • Objective: The objective of this study was to identify genes associated with 305-day milk yield (MY) and fat yield (FY) that also influence the adaptability of the Thai multibreed dairy cattle population to tropical conditions. Methods: A total of 75,776 imputed and actual single nucleotide polymorphisms (SNPs) from 2,661 animals were used to identify genomic regions associated with MY and FY using the single-step genomic best linear unbiased predictions. Fixed effects included herd-year-season, breed regression, heterosis regression and calving age regression effects. Random effects were animal additive genetic and residual. Individual SNPs with a p-value smaller than 0.05 were selected for gene mapping, function analysis, and quantitative trait loci (QTL) annotation analysis. Results: A substantial number of QTLs associated with MY (9,334) and FY (8,977) were identified by integrating SNP genotypes and QTL annotations. Notably, we discovered 17 annotated QTLs within the health and exterior QTL classes, corresponding to nine unique genes. Among these genes, Rho GTPase activating protein 15 (ARHGAP15) and catenin alpha 2 (CTNNA2) have previously been linked to physiological traits associated with tropical adaptation in various cattle breeds. Interestingly, these two genes also showed signs of positive selection, indicating their potential role in conferring tolerance to trypanosomiasis, a prevalent tropical disease. Conclusion: Our findings provide valuable insights into the genetic basis of MY and FY in the Thai multibreed dairy cattle population, shedding light on the underlying mechanisms of tropical adaptation. The identified genes represent promising targets for future breeding strategies aimed at improving milk and fat production while ensuring resilience to tropical challenges. This study significantly contributes to our understanding of the genetic factors influencing milk production and adaptability in dairy cattle, facilitating the development of sustainable genetic selection strategies and breeding programs in tropical environments.