• Korean Journal of Radiology
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• 제22권10호
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• pp.1719-1729
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• 2021

Objective: Emphysema and small-airway disease are the two major components of chronic obstructive pulmonary disease (COPD). We propose a novel method of quantitative computed tomography (CT) emphysema air-trapping composite (EAtC) mapping to assess each COPD component. We analyzed the potential use of this method for assessing lung function in patients with COPD. Materials and Methods: A total of 584 patients with COPD underwent inspiration and expiration CTs. Using pairwise analysis of inspiration and expiration CTs with non-rigid registration, EAtC mapping classified lung parenchyma into three areas: Normal, functional air trapping (fAT), and emphysema (Emph). We defined fAT as the area with a density change of less than 60 Hounsfield units (HU) between inspiration and expiration CTs among areas with a density less than -856 HU on inspiration CT. The volume fraction of each area was compared with clinical parameters and pulmonary function tests (PFTs). The results were compared with those of parametric response mapping (PRM) analysis. Results: The relative volumes of the EAtC classes differed according to the Global Initiative for Chronic Obstructive Lung Disease stages (p < 0.001). Each class showed moderate correlations with forced expiratory volume in 1 second (FEV₁) and FEV₁/forced vital capacity (FVC) (r = -0.659-0.674, p < 0.001). Both fAT and Emph were significant predictors of FEV₁ and FEV₁/FVC (R² = 0.352 and 0.488, respectively; p < 0.001). fAT was a significant predictor of mean forced expiratory flow between 25% and 75% and residual volume/total vital capacity (R² = 0.264 and 0.233, respectively; p < 0.001), while Emph and age were significant predictors of carbon monoxide diffusing capacity (R² = 0.303; p < 0.001). fAT showed better correlations with PFTs than with small-airway disease on PRM. Conclusion: The proposed quantitative CT EAtC mapping provides comprehensive lung functional information on each disease component of COPD, which may serve as an imaging biomarker of lung function.

• 혜화의학회지
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• 제28권2호
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• pp.20-28
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• 2019

Objectives : Hwangryunhaedok-tang. a traditional Korean herbal medicine, has been widely used for the treatment. This study is purposed to analyze the research trend of Hwangryunhaedok-tang in Korea for developing further research plan. Methods : A search of Korean research database( OASIS, RISS, Korean traditional knowledge portal, NDSL) was conducted to find studies for Hwangryunhaedok-tang. We analyzed studies by publish date, speciality, study method, and field of study. Result : 1. 2.65 papers were published annually on average. 2. After analyzing for the speciality of the journal, most of the papers were published in Traditional Korean Medicine. 3. After analyzing for the study method, in vivo was 33.96%, in vitro was 32.08% and quantitative inspection was 13.21% 4. After analyzing for the subject of the studies, beneficial effect was 81.13%, quantitative and qualitative analysis was 13.21%, toxicity was 3.77% 5. Papers on beneficial effect were classified by the type of diseases. Hwangryunhaedok-tang was most used in skin disease. Conclusions : Hwangryunhaedok-tang is effective in various category of diseases. This study will be useful to future researchers and clinicians to conduct a study on Hwangryunhaedok-tang.

• 한국어교육
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• 제28권1호
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• pp.79-111
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• 2017

This study is a trend analysis study that discusses the current status and directions of research methods of KAP research. The existing trend ana lysis studies dealing with research methods have problems in that the classification criteria of the studies used are rough and different from each other, rendering comparison between studies being difficult, and do not comprehensively cover research methods of diversified KAP research. Therefore, this study examined the research methods of KAP research from a critical point of view and suggested a set of classification criteria and an analysis framework that can be used consistently in classification and analysis of future KAP research methods. Based on the theoretical background of second language studies and applied linguistics, this study revised and supplemented Brown (2015)'s research method types and selected 289 journals and theses/dissertations from 2012 to 2016 and classified them into a new analysis framework. The primary and secondary studies, which are the major categories, were 219 and 70, respectively, so it was confirmed that there were much more primary studies. The primary studies then were subdivided into 128 qualitative research studies, 142 survey research studies, and 23 quantitative research studies, pointing to the trend that survey and qualitative research methods were preferred. In the qualitative research approaches, there were 21 action research studies, which were used the most. In addition, such qualitative research approaches as case studies and narrative inquiries which were difficult to find in the past, have gradually increased, confirming that the diversification of research methods is becoming common. However, there were still many studies that did not explicitly put forward research questions and there were many studies that did not report reliability and effect sizes in quantitative research. Of the 23 quantitative studies, only 50% reported reliability, and only three reported effect sizes. In order to enable systematic reviews (meta-analysis) of quantitative research and expect quality improvement of research in future KAP research, reporting of quantitative research should be done more systematically. This study is meaningful in that a systematic and detailed analysis framework was proposed to classify various research methods in the future and that the problems and directions for improvement of the KAP research methods were discussed through the analysis of the research trend of the KAP studies for the last 5 years.

• 대한설비공학회:학술대회논문집
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• 대한설비공학회 2006년도 하계학술발표대회 논문집
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• pp.970-975
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• 2006

In the high oil prices age, intensification of energy efficiency promotion in the building sector is required. Windows are dominating large percentage whole building loads, and are regarding as the primary target of energy efficiency. The purpose of this study is to draw up a technical counterplan for the intensification of windows energy efficiency and spread promotion by quantitative thermal performance with KS test method for a comparison between the general Pair glass windows and the Low-e pair glass windows.

• Genomics & Informatics
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• 제18권1호
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• pp.4.1-4.6
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• 2020

Transposable elements (TEs) constitute approximately half of Bovine genome. They can be a powerful species-specific marker without regression mutations by the structure variation (SV) at the time of genomic evolution. In a previous study, we identified the Hanwoo-specific SV that was generated by a TE-association deletion event using traditional PCR method and Sanger sequencing validation. It could be used as a molecular marker to distinguish different cattle breeds (i.e., Hanwoo vs. Holstein). However, PCR is defective with various final copy quantifications from every sample. Thus, we applied to the droplet digital PCR (ddPCR) platform for accurate quantitative detection of the Hanwoo-specific SV. Although samples have low allele frequency variation within Hanwoo population, ddPCR could perform high sensitive detection with absolute quantification. We aimed to use ddPCR for more accurate quantification than PCR. We suggest that the ddPCR platform is applicable for the quantitative evaluation of molecular markers.

• 한국국방경영분석학회지
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• 제27권2호
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• pp.56-75
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• 2001

Most O4I Systems are considered as one of the major system in future Information Warfare. However, it is difficult to measure the effectiveness of force improvement when C4I System is used with other weapon systems, quantitatively. In this Paper, we propose a quantitative method to evaluate the force improvement effectiveness of KNTDS(Korea Naval Tactical Data System). This method utilized the Lanchester's equations and its applications. We also showed a numerical example based on a given scenario in a sea battle and the ASP(Analytic Hierarchy Process) Method is applied to verify its results.

• 한국CDE학회논문집
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• 제11권2호
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• pp.148-155
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• 2006

This paper presents a new method for assessing the efficiency of production process plans using tolerance chart to lower production cost. The tolerance chart is used to predict the accuracy of a part that is to be produced following the process plan, and to carry out the quantitative measurement on the efficiency of the process plan. By comparing the values of design tolerances and their corresponding resultant tolerances calculated using the tolerance chart, the process plan that is incapable of satisfying the design requirements and the faulty production operations can be identified. Similarly, the process plan that imposes unnecessarily high accuracy and wasteful production operations can also be identified. For the latter, a quantitative measure on the efficiency of the process plan is introduced. The higher the unnecessary cost of the production, the poor is the efficiency of the process plan. A coefficient is introduced for measuring the process plan efficiency. The coefficient also incorporates two weighting factors to reflect the difficulty of manufacturing operations and number of dimensional tolerances involved. To facilitate the identification of the machining operations and the machined surfaces, which are related to the unnecessarily tight resultant tolerances caused by the process plan, a rooted tree representation of the tolerance chart is introduced, and its use is demonstrated. An example is presented to illustrate the new method. This research introduces a new quantitative process plan evaluation method that may lead to the optimization of process plans.

• 분석과학
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• 제33권5호
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• pp.209-214
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• 2020

This study has been carried out to develop a standard method for quantifying of 3 permitted artificial sweeteners (including sodium saccharine, aspartame, acesulfame potassium) contained in foods by HPLC-DAD. A simple and rapid sample pretreatment method was used to remove fat and protein from the test solution with Carrez clearing regent precipitant know to be effective for protein and fat removal. The artificial sweeteners in the test solution purified through sample pretreatment were detected by high performance liquid chromatograph using a Reverse phase C18 column (5 ㎛, 4.6 × 250 mm). The simultaneous quantitative test of 3 kinds of artificial sweeteners can be effectively performed on the high fat emulsified foods containing a large amount of fat. Using the established simultaneous quantitative test method, artificial sweeteners were tested in foods such as dairy products, snacks and chocolate. The results calibration curve showed good linearity with high regression coefficients and the result of recovery test showed satisfactory recoveries within 80~110 %.

• 대한건축학회논문집:구조계
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• 제34권3호
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• pp.77-86
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• 2018

Recently, Korean construction industry is moving from quantitative growth to qualitative growth. Among the changes in the construction industry, the competency of the project manager who represents the construction project as well as the construction company has been referred to as a factor that effects qualitative growth. This research utilized previous research analysis and expert interview in order to extract essential competency factors of a construction project manager. DEMATEL method was utilized to analyze the quantitative and objective causal relationship between the competency factors. The causal relationship of the competency factors were visualized through Digraph (directed graph) and competency areas of the project manager that requires strengthening were also suggested. Analysis result showed that the important competency categories of a project manager were Internal & External Communication, Project Management Body of Knowledge, and Inspirational Leadership. The analysis results of this research can be utilized in developing competency enhancement method for future project managers and as a basic data in developing an education program.

• 한국수학교육학회지시리즈C:초등수학교육
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• 제19권1호
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• pp.47-60
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• 2016

본 연구는 수학교육에서 혼합 연구방법(양적 연구방법과 질적 연구방법을 혼합한)을 활용한 연구에서 질적 연구 방법이 어떻게 적용되고 있는지를 분석하고, 질적 접근의 적용이 연구 목적 성취에 기여할 수 있는 시사점을 탐색하고 논의하고자 한다. 이러한 연구 목적을 달성하기 위하여, 본 연구에서는 한국수학교육학회의 초등수학교육 학회지에 2012년 게재된 전체 16편의 논문 중, 혼합 연구법을 활용한 논문 5편을 분석 대상으로 선정하였다. 비교 항목별 분석 결과를 양화된 수치로 간략하게 제시하던 기존의 혼합 연구물에 대한 분석 연구와는 달리, 본 연구는 질적 연구자의 관점에서, 자료 수집 및 자료 분석 방법, 연구 참여자 및 샘플링 선정 등을 중심으로 심도 있게 분석하여 그 결과와 시사점을 질적으로 제시하고 있다.