• Title/Summary/Keyword: Quantitative Methodology

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Development of new agrochemicals by quantitative structure-activity relationship (QSAR) methodology. III. 3D QSAR methodologies and computer-assisted molecular design (CAMD) (정량적인 구조-활성상관 (QSAR) 기법에 의한 새로운 농약의 개발. III. 3D QSAR 기법들과 컴퓨터를 이용한 분자설계(CAMD))

  • Sung, Nack-Do
    • The Korean Journal of Pesticide Science
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    • v.7 no.1
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    • pp.1-11
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    • 2003
  • Acoording to improvement of HTOS (high throughput organic synthesis) and HTS (high throughput screening) technique, the CoMFA (comparative molecular field analysis), CoMSIA (comparative molecular similarity indeces analysis) and molecular HQSAR (hologram quantitative structure-activity relationship) analysis techniques as methodology of computer assisted molecular design (CAMD) were introduced generally and summarized for some application cases.

An Inquiry about Mixed Methodology for Family Studies (가족연구를 위한 혼합방법론에 대한 고찰)

  • Yang, Sung-Eun
    • Journal of the Korean Home Economics Association
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    • v.44 no.9
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    • pp.1-8
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    • 2006
  • The purposes of the present article are to suggest pragmatism as offering a philosophical paradigm for mixed methods research, to explain the fundamental principles of mixed methodology, and to present examples of research for understanding how to apply it to family studies. Mixed methods research is the class of research where the researcher mixes or combines quantitative and qualitative techniques, methods, approaches, concepts or language into a single study. Mixed methodology has its roots in pragmatism, which is a new philosophical paradigm to criticize the traditional dualism and to endorse eclecticism and pluralism. The present article argues that mixed methods research has the potential to answer a broader and more complete range of research questions, and to provide strong evidence for a conclusion through convergence and corroboration of the qualitative and the quantitative methods.

A Study for the Service Quality Audit System Development based on the Analysis of Airline Cabin Service Process (항공사 기내서비스 프로세스분석에 근거한 서비스품질 감사시스템개발에 관한 연구)

  • Lee, Chi-Min;Kim, Youn-Sung
    • Journal of Korean Society for Quality Management
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    • v.40 no.3
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    • pp.406-414
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    • 2012
  • Purpose: In this study, we developed a service quality audit system through analyzing service processes of airlines' cabin service. Methods: Applying the qualitative approach to service processes analysis; 'service blueprint' methodology was developed, providing airlines a blueprint for cabin service and applying the quantitative service quality audit approach called 'walk-through audit', an audit methodology tailored to airline cabin service called PCPA (Passenger Cabin Patrol Audit) was developed. Results: This study tried to apply both the qualitative and the quantitative methodologies to develop service quality audit checklist and tried to develop details to systemize them into a new methodology. Conclusion: This study will be helpful for Airline services improvement by providing 'service quality audit model', so as to find out the problems and share those with the stakeholders.

Process Improvement in Software Companies: A Live Study at Motorola

  • Kumari, Neeraj
    • The Journal of Industrial Distribution & Business
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    • v.7 no.1
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    • pp.11-14
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    • 2016
  • Purpose - The study aims to show the successful application of Six Sigma in software companies for process improvement. Research design, data and methodology - A mixed methodology has been used which include both qualitative and quantitative research. In the qualitative research methodology part, a detailed and comprehensive literature study have been carried out. The literature study consists of articles, books, web materials, discussion forms and others. In the quantitative research methodology part, interviews have been conducted. Results - Six sigma is the practical application of a theoretical statistical measurement that equates to 3.4 defects per million opportunities -a position of practically zero defects for any process or service. Initially originating in Motorola Inc. in 1985 as a response to drastic quality improvement pressures from the threat of Japanese competition, it quickly gained many followers particularly G.E., Allied Signal, Ford Motor Company etc. and more recently attentions have shifted to service environments. There are still some problems and misconceptions existed about the applicability of Six Sigma in software companies. Conclusions - The paper concludes that Six Sigma can bring large benefits for software companies too. Furthermore, software companies have already started to implement Six Sigma approach, like Ericsson, Tata Consultancy Service, etc.

A Study on the System Design of Chemical Process using Quantitative Risk Assessment Methodology (정량적 위험성평가기법을 이용한 화학공정 시스템 구축에 관한 연구)

  • Byun, Yoon Sup
    • Journal of the Korean Institute of Gas
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    • v.18 no.6
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    • pp.32-39
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    • 2014
  • To ensure the reliability of the safety system so that handing large quantities of hazardous materials in chemical plant is considered basic information in chemical process design. However, the reliability of the production system may be reduced when the reliability of the safety system emphasized in order to ensure the safety of chemical process. It is necessary to balance the reliability of the production system and reliability of the safety. In this study, a quantitative risk assessment was performed by selecting the furnace process, which is widely used in the chemical plant in order to suggest a way to ensure the safety and productivity of chemical process, based on the quantitative data. Quantitative risk assessment methodology have been used directed graph analysis methodology. It is possible to evaluate the reliability of the safety system and the production system. In this study, the optimum system design requirement to improve the safety and the productivity of the furnace is two-out-of-three logic for TT and PT.

Quantitative Analysis of PET Measurements in Tumors (종양학 분야에서 양전자방출촬영을 이용한 정량분석)

  • Choi, Chang-Woon
    • 대한핵의학회:학술대회논문집
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    • 2001.05a
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    • pp.60-65
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    • 2001
  • The positron emission tomography (PET) has been used for the evaluation of the characteristics of various tumors. The role of PET in oncology has been evolved from a pure research tool to a methodology of enormous clinical potential. The unique characteristics of PET imaging make sophisticated quantitation possible. Several quantitative methods, such as standardized uptake values (SUV), simplified quantitative method, Patlak graphical analysis, and Sokoloff's glucose metabolism measurement, have been used in the field of oncology. However, each quantitative method has limitations of its own. For example, the SUV has been used as a quantitative index of glucose metabolism for tumor classification and monitoring response to treatment, even though it depends on blood glucose level, body configuration of patient, and scanning time. The quantitative methods of PET are reviewed and strategy for implementing these methods are presented.

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A Study of Human System Integration Methodology For the Mobile Industry Sustainability System Evaluation Model Design (모바일산업 지속가능 시스템 평가모델 설계를 위한 인간시스템통합 (HSI) 방법론 연구)

  • Kim, Sang Jin;Cha, Woo Chang
    • Journal of the Korean Society of Systems Engineering
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    • v.17 no.1
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    • pp.43-52
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    • 2021
  • The aim of this study is to propose the design suitable for sustainability evaluation model of the mobile industry considering system process (SEP). Although a quantitative evaluation was conducted on the link between the national sustainability report and the mobile industry, it was confirmed that it was difficult to identify stakeholders. So it is necessary to develop the design process suitable for the more operator-specific interfaces. The Human System Integration (HSI) methodology was proposed through linkage with work domain analysis. Agile methodology and Resilience engineering methodology were added for sustainable model design. The proposed sustainability system evaluation model is applied so that it can be easily used in all industries.

Reflection on Nursing Methodology (간호학 방법론에 대한 성찰)

  • 이은주;박영숙
    • Journal of Korean Academy of Nursing
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    • v.23 no.3
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    • pp.453-466
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    • 1993
  • Quantitative methodology has been the predominent methodology utilized in research in nursing. However since the 1970s qualitative methodology has also emerged as a useful methodology and has been utilized by many researchers. But in the use of this methodology, the philosophical, epistemelogical, and theoretical backgrounds have been neglected by many researchers. This paper reports a review of the literature on methodologies, quanitative and qualitative, used in nursing, and makes suggestions for future research directions. It explains why qualitative methodology has emerged as as effective methodology in nursing and discusses how the qualitative methodology differs from the quanitative one. A comparison of the two is made based on perspectives of humane being and human behavior as well as the development of nursing science. This paper also presents several views on change in nursing science, since viewpoint not only influences the determination of the current stage of nursing science but also the shaping of the future directions of nursing science and research. Scientific revolution by Kuhn, the evolutionary perspective by Toulmin, the transition of research tradition by Laudan. and convolutionary processes are presented. However, this paper indicates that it is too early to adopt these points of view, because the history of nursing science is too short. It suggests that nursing needs pluralism in philosophy, paradigms and theory, as well as in methodology. Although we experience paradoxes in adopting different perspectives in nursing, it is wise for us to continue to include a variety of viewpoints including those to which we are not accustomed, such as qualitative methodology, since we are not yet able to decide what is best for the development of nursing science.

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Quantitative Reliability Assessment for Safety Critical System Software

  • Chung, Dae-Won
    • Journal of Electrical Engineering and Technology
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    • v.2 no.3
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    • pp.386-390
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    • 2007
  • At recent times, an essential issue in the replacement of the old analogue I&C to computer-based digital systems in nuclear power plants becomes the quantitative software reliability assessment. Software reliability models have been successfully applied to many industrial applications, but have the unfortunate drawback of requiring data from which one can formulate a model. Software that is developed for safety critical applications is frequently unable to produce such data for at least two reasons. First, the software is frequently one-of-a-kind, and second, it rarely fails. Safety critical software is normally expected to pass every unit test producing precious little failure data. The basic premise of the rare events approach is that well-tested software does not fail under normal routine and input signals, which means that failures must be triggered by unusual input data and computer states. The failure data found under the reasonable testing cases and testing time for these conditions should be considered for the quantitative reliability assessment. We presented the quantitative reliability assessment methodology of safety critical software for rare failure cases in this paper.

Methodology of Mapping Quantitative Trait Loci for Binary Traits in a Half-sib Design Using Maximum Likelihood

  • Yin, Zongjun;Zhang, Qin;Zhang, Jigang;Ding, Xiangdong;Wang, Chunkao
    • Asian-Australasian Journal of Animal Sciences
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    • v.18 no.12
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    • pp.1669-1674
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    • 2005
  • Maximum likelihood methodology was applied to analyze the efficiency and statistical power of interval mapping by using a threshold model. The factors that affect QTL detection efficiency (e.g. QTL effect, heritability and incidence of categories) were simulated in our study. Daughter design with multiple families was applied, and the size of segregating population is 500. The results showed that the threshold model has a great advantage in parameters estimation and power of QTL mapping, and has nice efficiency and accuracy for discrete traits. In addition, the accuracy and power of QTL mapping depended on the effect of putative quantitative trait loci, the value of heritability and incidence directly. With the increase of QTL effect, heritability and incidence of categories, the accuracy and power of QTL mapping improved correspondingly.