• Title/Summary/Keyword: Quantitative MRI

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The quantitative analysis of Diffusion Weighted Imaging in Breast MRI (유방 MRI 검사에서 확산강조영상의 정량적 분석)

  • Cho, Jae-Hwan;Kim, Hyeon-Ju;Hong, Yin-Sik;Lee, Hae-Kag
    • Journal of the Korean Society of Radiology
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    • v.5 no.3
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    • pp.149-154
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    • 2011
  • The purpose of this study was to examine the usefulness of diffusion weighted images in breast MRI by performing a quantitative comparative analysis in patients diagnosed with DCIS. On a 3.0T MR scanner, diffusion weighted images and ADC map images were obtained from 20 patients histologically diagnosed with ductal carcinoma in situ (DCIS). The findings from the quantitative image analysis are the following: The diffusion weighted images showed higher SNR and CNR at the lesion area. In addition, the ADC values were lower at the lesion area.

Seed-Based Resting-State Functional MRI for Presurgical Localization of the Motor Cortex: A Task-Based Functional MRI-Determined Seed Versus an Anatomy-Determined Seed

  • Ji Young Lee;Yangsean Choi;Kook Jin Ahn;Yoonho Nam;Jin Hee Jang;Hyun Seok Choi;So Lyung Jung;Bum Soo Kim
    • Korean Journal of Radiology
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    • v.20 no.1
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    • pp.171-179
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    • 2019
  • Objective: For localization of the motor cortex, seed-based resting-state functional MRI (rsfMRI) uses the contralateral motor cortex as a seed. However, research has shown that the location of the motor cortex could differ according to anatomical variations. The purpose of this study was to compare the results of rsfMRI using two seeds: a template seed (the anatomically expected location of the contralateral motor cortex) and a functional seed (the actual location of the contralateral motor cortex determined by task-based functional MRI [tbfMRI]). Materials and Methods: Eight patients (4 with glioma, 3 with meningioma, and 1 with arteriovenous malformation) and 9 healthy volunteers participated. For the patients, tbfMRI was performed unilaterally to activate the healthy contralateral motor cortex. The affected ipsilateral motor cortices were mapped with rsfMRI using seed-based and independent component analysis (ICA). In the healthy volunteer group, both motor cortices were mapped with both-hands tbfMRI and rsfMRI. We compared the results between template and functional seeds, and between the seed-based analysis and ICA with visual and quantitative analysis. Results: For the visual analysis, the functional seed showed significantly higher scores compared to the template seed in both the patients (p = 0.002) and healthy volunteers (p < 0.001). Although no significant difference was observed between the functional seed and ICA, the ICA results showed significantly higher scores than the template seed in both the patients (p = 0.01) and healthy volunteers (p = 0.005). In the quantitative analysis, the functional seed exhibited greater similarity to tbfMRI than the template seed and ICA. Conclusion: Using the contralateral motor cortex determined by tbfMRI as a seed could enhance visual delineation of the motor cortex in seed-based rsfMRI.

A Study on MRI Semi-Automatically Selected Biomarkers for Predicting Risk of Rectal Cancer Surgery Based on Radiomics (라디오믹스 기반 직장암 수술 위험도 예측을 위한 MRI 반자동 선택 바이오마커 검증 연구)

  • Young Seo, Baik;Young Jae, Kim;Youngbae, Jeon;Tae-sik, Hwang;Jeong-Heum, Baek;Kwang Gi, Kim
    • Journal of Biomedical Engineering Research
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    • v.44 no.1
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    • pp.11-18
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    • 2023
  • Currently, studies to predict the risk of rectal cancer surgery select MRI image slices based on the clinical experience of surgeons. The purpose of this study is to semi-automatically select and classify 2D MRI image slides to predict the risk of rectal cancer surgery using biomarkers. The data used were retrospectively collected MRI imaging data of 50 patients who underwent laparoscopic surgery for rectal cancer at Gachon University Gil Medical Center. Expert-selected MRI image slices and non-selected slices were screened and radiomics was used to extract a total of 102 features. A total of 16 approaches were used, combining 4 classifiers and 4 feature selection methods. The combination of Random Forest and Ridge performed with a sensitivity of 0.83, a specificity of 0.88, an accuracy of 0.85, and an AUC of 0.89±0.09. Differences between expert-selected MRI image slices and non-selected slices were analyzed by extracting the top five significant features. Selected quantitative features help expedite decision making and improve efficiency in studies to predict risk of rectal cancer surgery.

Characteristics of Magnetic Resonance-Based Attenuation Correction Map on Phantom Study in Positron Emission Tomography/Magnetic Resonance Imaging System

  • Hong, Cheolpyo
    • Progress in Medical Physics
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    • v.31 no.4
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    • pp.189-193
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    • 2020
  • An MR-based attenuation correction (MRAC) map plays an important role in quantitative positron emission tomography (PET) image evaluation in PET/magnetic resonance imaging (MRI) systems. However, the MRAC map is affected by the magnetic field inhomogeneity of MRIs. This study aims to evaluate the characteristics of MRAC maps of physical phantoms on PET/MRI images. Phantom measurements were performed using the Siemens Biograph mMR. The modular type physical phantoms that provide assembly versatility for phantom construction were scanned in a four-channel Body Matrix coil. The MRAC map was generated using the two-point Dixon-based segmentation method for whole-body imaging. The modular phantoms were scanned in compact and non-compact assembly configurations. In addition, the phantoms were scanned repeatedly to generate MRAC maps. The acquired MRAC maps show differently assigned values for void areas. An incorrect assignment of a void area was shown on a locally compact space between phantoms. The assigned MRAC values were distorted using a wide field-of-view (FOV). The MRAC values also differed after repeated scans. However, the erroneous MRAC values appeared outside of phantom, except for a large FOV. The MRAC map of the phantom was affected by phantom configuration and the number of scans. A quantitative study using a phantom in a PET/MRI system should be performed after evaluation of the MRAC map characteristics.

MRI Quantification Analysis on Fall in Sick Times of the Cerebral Infarction Patients Using Object-Centered Hierarchical Planning (객체 중심 계층적 계획을 이용한 뇌경색 환자의 시기별 MRI 정량적 분석에 관한 연구)

  • Ha, Kwang;Jeon, Gye-Rok;Kim, Gil-Joong
    • Journal of Biomedical Engineering Research
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    • v.24 no.2
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    • pp.61-68
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    • 2003
  • This paper presents a quantitative analysis method for fall in sick times of the cerebral infarction patients using three types of magnetic resonance image, which play an important role in deciding method of medical treatment. For this object, image characteristics obtained by three radiographic methods of MRI and their relation were analyzed by means of object centered hierarchical Planning method. This methode presents an approach to the knowledge based processes for image interpretation and analysis. To compare three type of MRI. a multiple warping algorithm and affine transform method performed for image matching. Then each fall in sick times level of cerebral infarction was quantified and pseudo-color mapping performed by comparing gray level value one another according to Previously obtained hand maid data. The result of this study was compared to a medical doctors decision.

Evaluation of the Resolution Characteristics by Using American College of Radiology Phantom for Magnetic Resonance Imaging (자기공명영상에서 ACR 팬텀을 이용한 해상력 특성 평가)

  • Min, Jung-Whan;Jeong, Hoi-Woun;Han, Ji-Hyun;Lee, Si-Nae;Kim, Min-Ji;Kim, Seung-Chul
    • Journal of radiological science and technology
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    • v.45 no.1
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    • pp.11-17
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    • 2022
  • This study was purpose to quantitative assessment of the resolution characteristics by using American college of radiology(ACR) phantom for magnetic resonance imaging (MRI). The MRI equipment was used (Achiva 3.0T MRI, Philips system, Netherlands) and the head/neck matrix shim SENSE head coil were 32 channels(elements) receive MR coil. And the MRI equipment was used (Discovery MR 750, 3.0T MRI, GE medical system, America) and the head/neck matrix shim MC 3003G-32R 32-CH head coil were receive MR coil. As for the modulation transfer function(MTF) comparison result by using ACR magnetic resonance imaging phantom, the MTF value of the ACR standard T2 image in GE equipment is 0.199 when the frequency is 1.0 mm-1 and the MTF value of the hospital T2 image in Philips equipment is 0.528. It was used efficiently by using a general sequence more than the standard sequence method using the ACR phantom. In addition it is significant that the quantitative quality assurance evaluation method for resolution characteristics was applied mutatis mutandis, and the result values of the physical image characteristics of the 3.0T MRI device were presented.

Assessment of the Location of the Peroneus Longus Tendon in the Cuboid Groove Using 3D Isotropic Fast Spin-Echo MRI

  • Lee, Ji Yoon;Choo, Hye Jung;Lee, Sun Joo;Jung, Joon-Yong;Kim, Dong Wook;Baek, Jin Wook;Heo, Young Jin;Gwak, Heui-Chul
    • Investigative Magnetic Resonance Imaging
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    • v.24 no.1
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    • pp.21-29
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    • 2020
  • Purpose: To investigate normal location of the peroneus longus tendon (PL) in the cuboid groove by evaluating it between ankles with no significant abnormality (asymptomatic group) and those with retromalleolar PL dislocation (dislocation group) using three-dimensional isotropic fast spin-echo (3D-FSE) magnetic resonance imaging (MRI) of the ankle. Materials and Methods: Thirty-six and 32 3D-FSE ankle MRI were assigned to the asymptomatic group and the dislocation group, respectively. Using multiplanar reformatted 3D-FSE, qualitative PL location (i.e., outside, overlying, and inside in relation to the cuboid groove), quantitative PL location (i.e., distance between the proximal margins of PL and cuboid groove), and cuboid groove size were measured in lateral, middle, and medial levels of the cuboid groove. Results: In the asymptomatic group, 64%, 42%, and 11%, respectively, had the outside or overlying-located PL in lateral, middle, and medial levels of the cuboid groove and the quantitative location gradually decreased from lateral to medial level. Qualitative and quantitative PL locations were not significantly different between the asymptomatic group and dislocation group. Cuboid groove size showed significant negative correlation with quantitative PL location in both groups. Conclusion: Outside- or overlying-located PL in lateral and middle levels of the cuboid groove would be a normal finding, regardless of PL status at the retromalleolar level.

Quantitative Evaluation of the Corticospinal Tract Segmented by Using Co-registered Functional MRI and Diffusion Tensor Tractography (정상인에서 기능적 뇌 자기공명영상과 확산텐서영상 합성기법을 이용한 피질척수로의 위치에 따른 정량적 분석)

  • Jang, Sung-Ho;Hong, Ji-Heon;Byun, Woo-Mok;Hwang, Chang-Ho;Yang, Dong-Seok
    • Investigative Magnetic Resonance Imaging
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    • v.13 no.1
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    • pp.40-46
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    • 2009
  • Purpose : The purpose of this study was to investigate the quantitative evaluation of the corticospinal tract (CST) at the multiple levels by using functional MRI (fMRI) co-registered to diffusion tensor tractography (DTT). Materials and Methods : Ten normal subjects without any history of neurological disorder participated in this study. fMRI was performed at 1.5 T MR scanner using hand grasp-release movement paradigm. DTT was performed by using DtiStudio on the basis of fiber assignment continuous tracking algorithm (FACT). The seed region of interest (ROI) was drawn in the area of maximum fMRI activation during the motor task of hand grasp-release movement on a 2-D fractional anisotropy (FA) color map, and the target ROI was drawn in the cortiocospinal portion of anterior lower pons. We have drawn five ROIs for the measurement of FA and apparent diffusion coefficient (ADC) along the corona radiata (CR) down to the medulla. Results : The contralateral primary sensorimotor cortex (SM1) was mainly found to be activated in all subjects. DTT showed that tracts originated from SM1 and ran to the medulla along the known pathway of the CST. In all subjects, FA values of the CST were higher at the level of the midbrain and posterior limb of internal capsule (PLIC) than the level of others. Conclusion : Our study showed that co-registered fMRI and DTT has elucidated the state of CST on 3-D and analyzed the quantitative values of FA and ADC at the multiple levels. We conclude that co-registered fMRI and DTT may be applied as a useful tool for clarifying and investigating the state of CST in the patients with brain injury.

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Study on the Resolution Characteristics by Using Magnetic Resonance Imaging 3.0T (3.0T 자기공명영상을 이용한 해상력 특성에 대한 연구)

  • Min, Jung-Whan;Jeong, Hoi-Woun;Han, Ji-Hyun;Lee, Si-Nae;Han, Song-Yi;Kim, Ki-Won;Kim, Hyun-Soo;Son, Jin-Hyun
    • Journal of radiological science and technology
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    • v.43 no.4
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    • pp.251-257
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    • 2020
  • This study was purpose to quantitative evaluation of edge method of modulation transfer function(MTF) and physical image characteristics of by obtain the optimal edge image by using magnetic resonance imaging(MRI). The MRI equipment was used (MAGNETOM Vida 3.0T MRI, Siemense healthcare system, Germany) and the head/neck matrix shim MR coil were 20 channels(elements) receive coil. The MTF results of showed the best value of 0.294 based on the T2 Nyquist frequency of 1.0 mm-1. The MTF results of showed that the T1 image is 0.160, the T1 CE image is 0.250, T1 Conca2 image is 0.043, and the T1 CE (Concatenation) Conca2 image is 0.190. The T2 image highest quantitatively value for MTF. The physical image characteristics of this study were to that can be used efficiently of the MRI and to present the quantitative evaluation method and physical image characteristics of 3.0T MRI.

Evaluation of the Noise Power Spectrum by Using American College of Radiology Phantom for Magnetic Resonance Imaging (자기공명영상에서 ACR 팬텀을 이용한 잡음전력스펙트럼 평가)

  • Jung-Whan Min;Hoi-Woun Jeong
    • Journal of radiological science and technology
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    • v.47 no.1
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    • pp.21-28
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    • 2024
  • This study was purpose to quantitative evaluation of comparison of the image intensity uniformity and noise power spectrum (NPS) by using American college of radiology (ACR) phantom for magnetic resonance imaging (MRI). The MRI was used achiva 3.0T MRI and discovery MR 750, 3.0T, the head and neck matrix shim SENSE head coil were 32 channels receive MR coil. The MRI was used parameters of image sequence for ACR standard and general hospital. NPS value of the ACR standard T2 vertical image in GE equipment was 7.65E-06 when the frequency was 1.0 mm-1. And the NPS value of the ACR hospital T1 region of interest (ROI) 9 over all vertical image in Philips equipment was 9E-08 when the frequency was 1.0 mm-1 and the NPS value of the hospital T2 ROI 9 over all vertical image in Philips equipment was 1.06E-07 when the frequency was 1.0 mm-1. NPS was used efficiently by using a general hospital vertical sequence more than the standard vertical sequence method by using the ACR phantom. Furthermore NPS was the quantitative quality assurance (QA) assessment method for noise and image intensity uniformity characteristics was applied mutatis mutandis, and the results values of the physical imaging NPS of the 3.0T MRI and ACR phantom were presented.