• Title/Summary/Keyword: Quantitative Approaches

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Current Status of Quantitative Trait Locus Mapping in Livestock Species - Review -

  • Kim, Jong-Joo;Park, Young I.
    • Asian-Australasian Journal of Animal Sciences
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    • v.14 no.4
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    • pp.587-596
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    • 2001
  • In the last decade, rapid developments in molecular biotechnology and of genomic tools have enabled the creation of dense linkage maps across whole genomes of human, plant and animals. Successful development and implementation of interval mapping methodologies have allowed detection of the quantitative trait loci (QTL) responsible for economically important traits in experimental and commercial livestock populations. The candidate gene approach can be used in any general population with the availability of a large resource of candidate genes from the human or rodent genomes using comparative maps, and the validated candidate genes can be directly applied to commercial breeds. For the QTL detected from primary genome scans, two incipient fine mapping approaches are applied by generating new recombinants over several generations or utilizing historical recombinants with identity-by-descent (IBD) and linkage disequilibrium (LD) mapping. The high resolution definition of QTL position from fine mapping will allow the more efficient implementation of breeding programs such as marker-assisted selection (MAS) or marker-assisted introgression (MAI), and will provide a route toward cloning the QTL.

A System Dynamics Model for Quantitative Analysis of Patent Systems (특허 시스템의 정량 분석을 위한 시스템 다이내믹스 모형)

  • Yoon, Min-Ho
    • Korean System Dynamics Review
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    • v.17 no.2
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    • pp.33-56
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    • 2016
  • In this paper, a system dynamics model for explaining the application, grant and maintenance of patents is provided. Existing literatures regarding the patent application system are mostly econometric approaches that consider only economic variables such as GDP and R&D. The model in this paper includes patent variables such as disputes as well as economic variables. Moreover, we show that the model can be used in not only a quantitative prediction but also policy experiment. The results of the policy experiment shows that strengthening protection of patents tend to increase the propensity to patent more than R&D investment.

Biomedical Applications of Stereoscopy for Three-Dimensional Surface Reconstruction in Scanning Electron Microscopes

  • Kim, Ki Woo
    • Applied Microscopy
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    • v.46 no.2
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    • pp.71-75
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    • 2016
  • The scanning electron microscope (SEM) offers two-dimensional (2D) micrographs of three-dimensional (3D) objects due to its inherent operating mechanisms. To overcome this limitation, other devices have been used for quantitative morphological analysis. Many efforts have been made on the applications of software-based approaches to 3D reconstruction and measurements by SEM. Based on the acquisition of two stereo images, a multi-view technique consists of two parts: (i) geometric calibration and (ii) image matching. Quantitative morphological parameters such as height and depth could be nondestructively measured by SEM combined with special software programs. It is also possible to obtain conventional surface parameters such as roughness and volume of biomedical specimens through 3D SEM surface reconstruction. There is growing evidence that conventional 2D SEM without special electron detectors can be transformed to 3D SEM for quantitative measurements in biomedical research.

A Study on Evaluation Methodology of Intangible Assets (무형자산 평가 기법에 관한 연구)

  • Hwang, Young-Seob;Leem, Young-Moon
    • Proceedings of the Safety Management and Science Conference
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    • 2008.04a
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    • pp.47-51
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    • 2008
  • Recently, the development of technology has been rapidly proceeding with information technology in various fields. Due to their abstract properties, proper evaluation of intangible assets is very difficult compared to evaluation of tangible assets. Intangible assets are knowledge, technology, and design etc. In general there are two approaches to evaluate the intangible assets such as qualitative and quantitative approach. The qualitative approach contains scoring approach, profile approach, checklist approach, and quantitative approach. Quantitative approach contains cost approach, market approach, income approach, and real-option approach. As an initial step for evaluation of safe work environments, this study compares and analyzes evaluation methods of intangible assets.

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Evaluation of Economic Potential and Level of Concentration of the Regions of Kazakhstan

  • Nurlanova, Nailya K.;Kireyeva, Anel A.;Ruzanov, Rashid M.
    • The Journal of Asian Finance, Economics and Business
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    • v.4 no.2
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    • pp.37-44
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    • 2017
  • This research is devoted to the development of methods general and standard methodological approaches and approbation those for the evaluation of economic potential and level of concentration of the regions of Kazakhstan. This paper presents the results of development of the authors on the selection and justification of the methodological approaches for quantitative evaluation of the economic potential (the degree of territorial differentiation of the profile) and concentration of regions. In this study, we used scientific methods: method of analysis the main trends of economic development, and method of evaluation of concentration of the region. Based on the analysis of foreign techniques developed and tested methodical approaches to the assessment of the economic potential (index and coefficient methods). Proposed methodological approaches to the assessment profile of the territory and developed a system of indicators, which includes an aggregated index of spatial concentration, which accurately reflects the concentration of production in the region. This study shows the results of the analysis of the potential regional disparities and trends of economic development of Kazakhstan. By using, the proposed methodology shows the possibility of their use; we calculated the indicators of integrated assessment of the economic potential and indicators of spatial concentration.

Data-Driven Approaches for Evaluating Countries in the International Construction Market

  • Lee, Kang-Wook;Han, Seung H.
    • International conference on construction engineering and project management
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    • 2015.10a
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    • pp.496-500
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    • 2015
  • International construction projects are inherently more risky than domestic projects with multi-dimensional uncertainties that require complementary risk management at both the country and project levels. However, despite a growing need for systematic country evaluations, most studies have focused on project-level decisions and lack country-based approaches for firms in the construction industry. Accordingly, this study suggests data-driven approaches for evaluating countries using two quantitative models. The first is a two-stage country segmentation model that not only screens negative countries based on country attractiveness (macro-segmentation) but also identifies promising countries based on the level of past project performance in a given country (micro-segmentation). The second is a multi-criteria country segmentation model that combines a firm's business objective with the country evaluation process based on Kraljic's matrix and fuzzy preference relations (FPR). These models utilize not only secondary data from internationally reputable institutions but also performance data on Korean firms from 1990 to 2014 to evaluate 29 countries. The proposed approaches enable firms to enhance their decision-making capacity for evaluating and selecting countries at the early stage of corporate strategy development.

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Men's information search and purchasing behavior related to cosmetic involvement focusing on Korean men in their 20s and 30s (20~30대 남성의 화장품 관여유형에 따른 정보탐색과 구매행동특성)

  • Hong, Hye Rim;Baek, Kyoungjin
    • The Research Journal of the Costume Culture
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    • v.25 no.6
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    • pp.804-818
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    • 2017
  • The purpose of this study was to examine the differences of the information searches and purchasing behavior Korean men in their 20s and 30s, focusing on cosmetic involvement. Research methods consisted of qualitative and quantitative approaches. For the qualitative approach, in-depth interviews and participant observations were conducted to investigate male customers' cosmetic characteristics in information searches and purchasing behavior. Then, the study conducted a quantitative study methodology based on the questionnaires from the in-depth interviews, participant observations, and literature review. The study surveyed 340 Korean men in their 20s and 30s. The cosmetic involvement of the target group was classified into the amusing high-involvement group, the rational low-involvement group, and the obligatory high-involvement group. The results from this study indicated that the groups of male customers classified by cosmetic involvement showed statistically significant differences in terms of information searches and purchasing behaviors. Especially, the obligatory high-involvement group generally displayed high-involvement traits likewise the amusing high-involvement, was more similar to the rational low-involvement group regarding cost effectiveness than the obligatory high-involvement group. Moreover, the classifications of men generally had different characteristics of cosmetic purchasing behavior and information searches than women. This study has a distinctive significance compared with other studies in discovering differences of cosmetic purchasing behaviors of Korean men in their 20s and 30s' cosmetic involvement groups classified using qualitative and quantitative approaches.

Prototype Extraction for the Categorization of Lotus and Crane Patterns Using Qualitative and Quantitative Approaches (질적, 양적 접근방법에 의한 연화문, 사문의 분류원형 추출)

  • 장수경;김재숙
    • Journal of the Korean Society of Clothing and Textiles
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    • v.20 no.6
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    • pp.1016-1026
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    • 1996
  • The purpose of this study was to extract protypes from features and concrete images of Lotus and Crane patterns. A qualitative and a quantitative methods were used. Qualitative informations were obtained from depth Interviews for pattern selection and feature extraction, and quantitative informations from a quail-experiment for pattern caregorization. The subjects were 20 female design students and non-design, students in Teajon. The results were summerized into a similarity metrix which was interpreted by the cluster analysis and the multi-dimensional scling(MDS). The patterns for the study were grouped into 8 clusters. Four dimensions were chosen for the MDS. The location of each pattern was visualized in a 2-dimesional spaces and the location of each cluster in a 3-dimensional spaces. The first dimension, "Lotus" vs "Crane" refired to pattern types, and the second dimension, "realistic" vs "transformable", the transformability. The third dimension, "simple" vs "complex", refired to the degree of simplification, and the forth dimension, "continuous" vs "discontinuous", continuity. The results of the Quantitative analysis could be summerized into 3-level prototype hiararchy In the first level, the patterns were devided clearly into two groups. Lotus and Crane by pattern types. In the second levelk, each group was devided into twosubgroups by continuity. In the third, each subgroup was divided into four subgroups by transformability and the degree of simplification. Four protypes, the final targets of the present study, were extracted from the third level. The are Stylized, Realistic, Decorative, Abstract types.d from the third level. The are Stylized, Realistic, Decorative, Abstract types.

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A Classification of Research Types and Trend Analysis of Research Methods in Korean for Academic Purposes (학문 목적 한국어교육의 연구 유형 분류와 연구 방법의 동향 분석)

  • Na, Wonju;Joo, Hyunha;Kim, Youngkyu
    • Journal of Korean language education
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    • v.28 no.1
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    • pp.79-111
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    • 2017
  • This study is a trend analysis study that discusses the current status and directions of research methods of KAP research. The existing trend ana lysis studies dealing with research methods have problems in that the classification criteria of the studies used are rough and different from each other, rendering comparison between studies being difficult, and do not comprehensively cover research methods of diversified KAP research. Therefore, this study examined the research methods of KAP research from a critical point of view and suggested a set of classification criteria and an analysis framework that can be used consistently in classification and analysis of future KAP research methods. Based on the theoretical background of second language studies and applied linguistics, this study revised and supplemented Brown (2015)'s research method types and selected 289 journals and theses/dissertations from 2012 to 2016 and classified them into a new analysis framework. The primary and secondary studies, which are the major categories, were 219 and 70, respectively, so it was confirmed that there were much more primary studies. The primary studies then were subdivided into 128 qualitative research studies, 142 survey research studies, and 23 quantitative research studies, pointing to the trend that survey and qualitative research methods were preferred. In the qualitative research approaches, there were 21 action research studies, which were used the most. In addition, such qualitative research approaches as case studies and narrative inquiries which were difficult to find in the past, have gradually increased, confirming that the diversification of research methods is becoming common. However, there were still many studies that did not explicitly put forward research questions and there were many studies that did not report reliability and effect sizes in quantitative research. Of the 23 quantitative studies, only 50% reported reliability, and only three reported effect sizes. In order to enable systematic reviews (meta-analysis) of quantitative research and expect quality improvement of research in future KAP research, reporting of quantitative research should be done more systematically. This study is meaningful in that a systematic and detailed analysis framework was proposed to classify various research methods in the future and that the problems and directions for improvement of the KAP research methods were discussed through the analysis of the research trend of the KAP studies for the last 5 years.

Advancing Risk Assessment through the Application of Systems Toxicology

  • Sauer, John Michael;Kleensang, Andre;Peitsch, Manuel C.;Hayes, A. Wallace
    • Toxicological Research
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    • v.32 no.1
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    • pp.5-8
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    • 2016
  • Risk assessment is the process of quantifying the probability of a harmful effect to individuals or populations from human activities. Mechanistic approaches to risk assessment have been generally referred to as systems toxicology. Systems toxicology makes use of advanced analytical and computational tools to integrate classical toxicology and quantitative analysis of large networks of molecular and functional changes occurring across multiple levels of biological organization. Three presentations including two case studies involving both in vitro and in vivo approaches described the current state of systems toxicology and the potential for its future application in chemical risk assessment.