• Title/Summary/Keyword: Quality safety

Search Result 5,001, Processing Time 0.051 seconds

The Quality Certification of Railway Components for Safety Guarantee (안전성 확보를 위한 철도용품의 품질인증)

  • Kim Jeongguk;Kim Jin-Hwan;Kwon Sung-Tae;Baek Seung-Koo
    • Proceedings of the KSR Conference
    • /
    • 2005.11a
    • /
    • pp.27-31
    • /
    • 2005
  • In order to guarantee the safety of railway, the Railway Safety Law (RSL) and ordinances have been enforced. In RSL, the quality certification is required to guarantee the safety and performance of railway components. Therefore, in this investigation, the detailed guidelines and main contents for the enforcement of quality certification for railway components will be suggested, and the detailed items including the procedures, subjects, management, etc., will be addressed.

  • PDF

Immunomodulatory Properties of Lactobacillus plantarum NC8 Expressing an Anti-CD11c Single-Chain Fv Fragment

  • Liu, Jing;Yang, Guilian;Gao, Xing;Zhang, Zan;Liu, Yang;Yang, Xin;Shi, Chunwei;Liu, Qiong;Jiang, Yanlong;Wang, Chunfeng
    • Journal of Microbiology and Biotechnology
    • /
    • v.29 no.1
    • /
    • pp.160-170
    • /
    • 2019
  • The lactic acid bacteria species Lactobacillus plantarum (L. plantarum) has been used extensively for vaccine delivery. Considering to the critical role of dendritic cells in stimulating host immune response, in this study, we constructed a novel CD11c-targeting L. plantarum strain with surface-displayed variable fragments of anti-CD11c, single-chain antibody (scFv-CD11c). The newly designed L. plantarum strain, named 409-aCD11c, could adhere and invade more efficiently to bone marrow-derived DCs (BMDCs) in vitro due to the specific interaction between scFv-CD11c and CD11c located on the surface of BMDCs. After incubation with BMDCs, the 409-aCD11c strain harboring a eukaryotic vector pValac-GFP could lead to more efficient expression of GFP compared with wild-type strains shown by flow cytometry analysis, indicating the enhanced translocation of pValac-GFP from L. plantarum to BMDCs. Similar results were also observed in an in vivo study, which showed that oral administration resulted in efficient expression of GFP in both Peyer's patches (PP) and mesenteric lymph nodes (MLNs) within 7 days after the last administration. In addition, the CD11c-targeting strain significantly promoted the differentiation and maturation of DCs, the differentiation of $IL-4^+$ and $IL-17A^+$ T helper (Th) cells in MLNs, as well as production of $B220^+$ $IgA^+$ B cells in the PP. In conclusion, this study developed a novel DC-targeting L. plantarum strain which could increase the ability to deliver eukaryotic expression plasmid to host cells, indicating a promising approach for vaccine study.

Safety Management for Small Food Manufactures (10인 이하 농식품 사업장의 안전관리)

  • Lee, Kwan Suk;Chung, Da Yeh
    • Journal of the Korean Society of Safety
    • /
    • v.28 no.1
    • /
    • pp.109-116
    • /
    • 2013
  • The objective of this study is to develop a new system that is simpler to be used to keep the safe workplace at the small food manufacturers which employees less than 10 persons. The number of these small food manufacturers is 13,853 and account for almost 80% of all food manufacturers. Most of these companies do not pay attention to safety and thus keep high accident potential. It is very important to persuade these companies to manage safety but they can hardly handle the complicated requirements of safety, health, quality, food quality, and musculoskeletal disorders intervention. This system is intended to develop a system which can be easily implemented but comprehensive to reflect main points in safety management, musculoskeletal disorders intervention,. ISO 9001, ISO 14001, KOSHA 18001, GAP and ISO 22000.

Analysis of Quality Change Based on Storage Conditions to Set the Use-by date of Bakery Breads (베이커리 식빵의 소비기한 설정을 위한 보관 방법에 따른 품질 변화 연구)

  • Sun Hye Hwang;Ji Yeon Choi;Min Joo Kim;Yong Sun Cho
    • Journal of Food Hygiene and Safety
    • /
    • v.38 no.4
    • /
    • pp.236-245
    • /
    • 2023
  • In this study, the quality safety limit period of seven types of bakery bread was analyzed, and their use-by date was calculated. For evaluating product quality, storage conditions were set as 5, 15, 25, and 35℃ for 50 days, and moisture, microorganisms, sensory characteristics, and dominant bacteria were examined. The quality and safety standards followed the Korea Food Code and Korean industrial standards (KS). The results showed that all products stored at 5℃ satisfied the standard for bacterial count for day 50, but the sensory quality was below the standard level. Samples stored at 15℃ showed high variability from 3-39 days. At 25℃, a quality safety limit period of 2-20 days was set, and one sample was found to have the same shelf life. Bread stored at 35 ℃ had the shortest quality safety limit period. Considering a safety factor of 0.87, a use-by date period of 1.7-13.1 days was calculated. Therefore, setting the use-by date according to the product type is necessary, even for the same product category. Among the bread products sold in bakeries, those managed as room temperature products (1-35℃) can be distributed and stored in a temperature range of up to 35℃. Overall, this study demonstrates the importance of setting a quality retention period based on the product characteristics and carefully considering the safety factor.

A Study on the Application of Quality System Standards in the Safety Certification of LUAVs (무인동력비행장치 안전성인증에서 품질시스템 기준 적용 방안 연구)

  • Ji-Hun Kwon;Shin-Duck Kang;Tae-Seok Oh;Seok-Min Pae;Sauk-Hoon Im
    • Journal of Aerospace System Engineering
    • /
    • v.18 no.2
    • /
    • pp.64-70
    • /
    • 2024
  • The demand for safety certification of Light Unmanned Aerial Vehicles (LUAVs), weighing between 25kg and 150kg, is rapidly increasing in Korea. Unfortunately, the number of LUAV safety certification failures is also on the rise, with manufacturing quality issues being identified as the main culprit. However, there is a lack of quality system standards for manufacturers within the LUAV safety certification system. As a result, this paper aims to analyze the domestic safety certification system and the quality standards set by the American Society for Testing and Materials (ASTM) for small Unmanned Aerial Systems (sUAS). The goal is to establish quality system inspection standards specifically tailored for LUAV manufacturers. To achieve this, we propose additional inspection items that reflect the characteristics of the manufacturing quality system. These items will be identified through on-site inspections of LUAV manufacturers, ensuring that the resulting quality system standard aligns with the actual situation of domestic manufacturers. In order to gauge the feasibility and effectiveness of the proposed quality system standard, we conducted a survey of seven domestic LUAV manufacturers.

The Effects of Job Quality on the Health of Wage Workers: Congruence between the Hard and Soft Job Quality

  • KonShik Kim
    • Safety and Health at Work
    • /
    • v.14 no.1
    • /
    • pp.31-42
    • /
    • 2023
  • Background: This study analyzes the linear and non-linear effects of the hard and soft dimensions of job quality on the overall health of wage workers. It also examines the congruence or fit between the hard and soft job quality on the overall health of wage workers. Methods: This study measured thirty indicators that constitute job quality and reduced the indicators into twelve sub-dimensions of job quality using reflective factor analysis. In addition, this study derived two dimensions of job quality from the twelve subdimensions, namely the hard and soft job quality using formative factor analysis. This paper applied the response surface analysis to analyze the congruence effect between the two dimensions of job quality. Results: A logarithmic relationship was found between the dimension of hard job quality and the worker's overall health. This study also verified that the congruence effect between the two dimensions of job quality does not exist, and the combined effect of job quality is lower when the two dimensions of job quality are at the same level than the effect when either level of job quality is high or low. Conclusions: Although hard and soft job quality has independent positive effects on the overall health of wage workers, the two dimensions of job quality are not congruent or not in harmony with each other. This incongruence between hard and soft job quality, together with a higher impact of hard job quality, suggests that the role of soft job quality on overall health is relatively limited.

Evaluation of Industrial Hygiene Laboratories by on-Site Investigation for Revised Quality Control System (개정된 정도관리제도를 적용한 작업환경측정기관의 실험실 현장 평가)

  • Shin, Jung-Ah;Yi, Gwang-Yong;Park, Seung-Hyun
    • Journal of Korean Society of Occupational and Environmental Hygiene
    • /
    • v.23 no.3
    • /
    • pp.243-249
    • /
    • 2013
  • Objectives: This study assessed the status of domestic industrial hygiene laboratories using data from on-site investigation for revision of quality control systems in 2012-2013. Methods: The target laboratories were 60 industrial hygiene laboratories chosen by random selection and nationwide distribution which had participated in on-site investigations for revision of quality control systems from March 2012 to August 2013. The investigation was performed on-site following standard quality control procedures. The score between each group was compared using Mann-Whitney and Kruskal-Wallis tests, and the correlation between analytical career, sex, academic major of analyst and score of analytical performance was expressed as Spearman's rank correlation coefficient. Results: The assessment revealed that the items to be improved, in sequence, were effort at staff training (score 65.5), ability to calculate data (score 73.4), establishment of internal quality control guidelines (score 75.7), laboratory facilities (score 77.1), degree of understanding and skill at gas chromatography (score 77.1). Analysis performance showed a positive correlation with career of analyst (r=0.56, p<0.01). Conclusions: The practice of on-site investigation for quality control systems showed the current status of industrial hygiene laboratories in the first trial. There were many laboratories which needed improvement and development of analytical systems. This assessment can provide information for the systematic operation and improvement of facilities at each laboratory. Further practice of this investigation will lead to a proficiency testing and accreditation system for autonomous quality control as is the practice in many countries, rather than mandatory practice by legal regulation.

The Task and Role of the Quality Improvement Facilitator (QI전담자의 주요 업무 및 역할 규명)

  • Kim, Moon-sook;Kim, Hyun-ah;Kim, Yoon-sook
    • Quality Improvement in Health Care
    • /
    • v.21 no.2
    • /
    • pp.40-56
    • /
    • 2015
  • Objectives: To outline overall duties of quality improvement (QI) performers within a health care organization, thus describing their key tasks, including task element-related frequency, importance and difficulty in enough detail. Methods: A DACUM (Developing A CurriculUM) workshop took place to outline overall job activities of QI performers. To examine the scope of their duty and task, we performed a questionnaire survey of 338 QI performers from 111 hospitals. Results: The results of our survey showed that for the task assigned to each QI performer, there were 10 duties, 31 tasks and 119 task elements. Respondents cited a project planning as the most frequent/important duty, and a research was the highest level of difficulty in their duty. They also said that the most frequent task was index management, the most important task was a business plan, and the highest level of difficulty was a practical application of QI research. QI performers added that the most frequent task element was receipt of patient safety reporting in patient safety system, the most important task element was an analysis for patient safety and its improvement, and the highest level of difficulty was a regional influence analysis related to the patient safety and its improvement. Conclusion: To ensure that QI performers play a pivotal role as a manager to better improve patient safety and the quality of health care services, proper training program for them should be developed by reflecting the results of our study.

Effect of bamboo shoot dietary fiber on gel properties, microstructure and water distribution of pork meat batters

  • Li, Ke;Liu, Jun-Ya;Fu, Lei;Zhao, Ying-Ying;Zhu, He;Zhang, Yan-Yan;Zhang, Hua;Bai, Yan-Hong
    • Asian-Australasian Journal of Animal Sciences
    • /
    • v.33 no.7
    • /
    • pp.1180-1190
    • /
    • 2020
  • Objective: To develop healthier comminuted meat products to meet consumer demand, the gel properties, rheological properties, microstructure and water distribution of pork meat batters formulated with various amounts of bamboo shoot dietary fiber (BSDF) were investigated. Methods: Different levels of BSDF (0% to 4%) were added to pork batters, and the pH, color, water-holding capacity, texture and rheological properties of pork batters were determined. Then, pork batters were analyzed for their microstructure and water distribution using scanning electron microscopy (SEM) and low-field nuclear magnetic resonance (LF-NMR). Results: Compared with the control, BSDF addition into meat batters showed a significant reduction in L*-value and a significant increase in b*-value (p<0.05). BSDF addition of up to 4% reduced the pH value of pork batters by approximately 0.15 units; however, the cooking loss and expressible water loss decreased significantly (p<0.05) with the increased addition of BSDF. The hardness and gel strength were noticeably enhanced (p<0.05) as the content of BSDF increased. The rheological results showed that BSDF added into pork batters produced higher storage modulus (G') and loss modulus (G") values. The SEM images suggested that the addition of BSDF could promote pork batters to form a more uniform and compact microstructure. The proportion of immobilized water increased significantly (p<0.05), while the population of free water was decreased (p<0.05), indicating that BSDF improved the water-holding capability of pork batters by decreasing the fraction of free water. Conclusion: BSDF could improve the gel properties, rheological properties and water distribution of pork meat batters and decrease the proportion of free water, suggesting that BSDF has great potential as an effective binder in comminuted meat products.

An Analysis on the HMR Purchasing Behavior based on the Life Style of the Customers of Convenience Stores

  • Ahn, Sun-Choung
    • Culinary science and hospitality research
    • /
    • v.23 no.6
    • /
    • pp.36-46
    • /
    • 2017
  • In this study, the influence of the life style on the HMR purchasing behaviors and repurchasing intents and the purchasing behavior on the repurchasing intent were examined in order to provide the basic data for developing competitive HMR product and invigoration of marketing. As results, of the life style factors, the health affected the quality, the taste the convenience and safety, and the economy the convenience, and the convenience the quality, and the safety the safety, significantly. Of the life style factors, health affected the repurchasing intentions negatively, while taste affected the repurchasing intent positively. Of the HMR selection properties, quality, convenience, and safety all affected the repurchasing intent positively. It can be conducted from the study that it is necessary to develop a strategy to enhance the quality and safety of the HMR and enhance the taste and economy of the HMR products for the taste and economy-oriented customers. When developing a new HMR product, the development and formulation of the strategy for quality, convenience, and safety and the overall strategy that covers from production, logistics, sales, and promotion, are supposed to be well established and discussed.