• Genomics & Informatics
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• v.17 no.3
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• pp.32.1-32.6
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• 2019

Currently, Illumina sequencers are the globally leading sequencing platform in the next-generation sequencing market. Recently, MGI Tech launched a series of new sequencers, including the MGISEQ-2000, which promise to deliver high-quality sequencing data faster and at lower prices than Illumina's sequencers. In this study, we compared the performance of two major sequencers (MGISEQ-2000 and HiSeq 4000) to test whether the MGISEQ-2000 sequencer delivers high-quality sequence data as suggested. We performed RNA sequencing of four human colon cancer samples with the two platforms, and compared the sequencing quality and expression values. The data produced from the MGISEQ-2000 and HiSeq 4000 showed high concordance, with Pearson correlation coefficients ranging from 0.98 to 0.99. Various quality control (QC) analyses showed that the MGISEQ-2000 data fulfilled the required QC measures. Our study suggests that the performance of the MGISEQ-2000 is comparable to that of the HiSeq 4000 and that the MGISEQ-2000 can be a useful platform for sequencing.

• Journal of the Korean Chemical Society
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• v.44 no.1
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• pp.10-16
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• 2000

In general, acid rain is unbuffered solution with low ionic strength and high resistance. Therefore during the pH measurement of acid rain, error can be occurred due to the liquid junction potential difference between the sample and the standard solution. Actually the average conductivity of rain in Taeduk Science Town during 1998 is 12.8 ${\mu}S/cm$, while that of pH standmd solutions is about 5,980 ${\mu}S/cm$. There is a large difference in ionic strength. To compensate the bias due to residual liquid junction potentials, a quality control standard(QCS) of dilute sulfuric acid, which has the conductivity and pH values simikw to rain, was prepared. The pH of QCS solution was determined using the hydrogen electrode system without liquid junction, and compensation has been made for the bias terms by performing the pH measurements with glass electrode. On the basis of this compensation method, the pH vaiues of rain in Taeduk Science Town during 1998 were measured.

• The Journal of the Korea Contents Association
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• v.10 no.4
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• pp.45-54
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• 2010

In this paper, we propose a quality interworking control system to enhance user's quality satisfaction in NGN environment by controling QoS parameters related with QoE in network layer when service user's QoE using variance multimedia service is poor. The proposed system gathers QoS parameter information in network layer through control packet such as RTCP, and evaluates QoE of multimedia service using these QoS parameter information. Comparing the evaluated QoE with the measured QoE in application layer, QCS judges quality degradation, deduces related QoS parameters and decides relative importance of each parameter when QoE is lower than threshold value. QCS generates QoS control values which is based on routing and switching policy in service quality control system(SCS) and forwards them to SCS. Through this proposed system, service and network providers can provide multimedia services of enhanced quality to service users taking account of service characteristic and network performance.

• Journal of the Korean Society for Railway
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• v.8 no.3
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• pp.286-292
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• 2005

In this paper, we introduce IEC 60300(Dependability program management) into urban transit system, and propose effective method to apply IEC 60300 to Subway Corporation. The dependability is the collective term used to describe the availability performance and its influencing factors such as reliability performance, maintainability performance and maintenance support performance. A dependability program covers all phases of a system's life cycle from planning to operation and possibly disposal, and is composed of program elements divided into tasks.

• Proceedings of the Korean Statistical Society Conference
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• 2003.10a
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• pp.53-58
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• 2003

최근 경제 사회의 급속한 발전에 따라 개인의 활동분야가 다양해지고 개인비밀보호 인식이 커지면서 응답자들이 통계조사에 잘 협조하지 않는 경우가 늘어나고 있다. 따라서 대부분의 통계를 현장조사에 의존하여 생산하고 있는 통계청에서는 현장조사 결과물의 품질상태에 좀 더 관심을 가져야만 하게 되었다. 이러한 현장조사에 대한 풀질관리의 일환으로 현재 통계청에서는 통계별 조사대상으로부터 품질관리표본(Quality Control Sample)을 추출하고 이를 대상으로 리인터뷰를 실시함으로써 응답오차측정, 조사현장의 실터파악, 응답자 의견수렴 등에 활용하고 있다. 리인터뷰는 조사직원의 고의적인 자료조작 또는 보충교육 필요성 등 현장조사업무를 평가하거나 응답분산(simple response variation), 응답편의(response bias) 등을 산출하고, 이를 분석하는 모델을 이용하여 응답결과의 신뢰도를 분석하는데 목적을 두고 있다. 본 연구에서는 품질관리표본(QC Sample) 설계 및 추출, 리인터뷰 시나리오개발, CATI(Computer Assisted Telephone Interviewing)를 이용한 리인터뷰 기법 등을 통계청 사업체조사 모니터링 사례를 중심으로 설명하고 조사직원 특성별 응답오차 측정 및 비교, 정확성 항목에 대한 차이분석 등 격과에 대하여 논하고자 한다.

• YAKHAK HOEJI
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• v.51 no.3
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• pp.174-178
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• 2007

A reverse-phase high performance liquid chromatography method with electrospray ionization and detection by mass spectrometry is described for the simultaneous determination of doxifluridine and its active metabolite 5-flu-orouracil (5-FU) in monkey serum. The method has greater sensitivity and simpler process than previous published methods with good accuracy and precision. A proper liquid/liquid extraction was used to extract simultaneously doxifluridine and 5-FU which has considerable difference in the polarity. Extracts were analyzed using LC/MS/MS providing a short analysis time within 5 min. The lower limit of quantification was validated at 10.0 ng/ml of serum for both doxifluridine and 5-FU. Accuracy and precision of quality control (QC) samples for both analytes met FDA Guidance criteria of ±15% for average QC accuracy with coefficients of variation less than 15%. The method will be applicable for preclinical studies and bioequivalence studies.

• Journal of the Korea Safety Management & Science
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• v.26 no.2
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• pp.107-115
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• 2024

This study conducted frequency analysis, reliability analysis, descriptive statistics, and correlation analysis to determine the impact of quality control managers' perception and implementation of KS certification factory inspection evaluation items on follow-up management. Through a multiple linear regression model, the influence of KS certification officer's awareness and implementation of KS certification factory inspection on post management was found to have a positive (+) influence on post management, with implementation having a greater influence on post management than awareness. It was having an impact. The independent variable (perception) has a statistically significant impact on the mediating variable (execution), and in the stage of verifying the mediating effect, the influence of the independent variable (perception) on the dependent variable (follow-up management) has a statistically significant impact. , In the stage where the independent variable (perception) and the mediator (implementation) are input simultaneously, both the independent variable and the mediator have a statistically significant effect on the dependent variable, indicating that there is a mediation effect.

• Design & Manufacturing
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• v.16 no.4
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• pp.52-59
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• 2022

Currently, Korea is an aging society and is expected to become a super-aged society in about four years. X-ray devices are widely used for early diagnosis in hospitals, and many X-ray technologies are being developed. The development of X-ray device technology is important, but it is also important to increase the reliability of the device through accurate data management. Sensor nodes such as temperature, voltage, and current of the diagnosis device may malfunction or transmit inaccurate data due to various causes such as failure or power outage. Therefore, in this study, the temperature, tube voltage, and tube current data related to each sensor and detection circuit of the diagnostic X-ray imaging device were measured and analyzed. Based on QC data, device failure prediction and diagnosis algorithms were designed and performed. The fault diagnosis algorithm can configure a simulator capable of setting user parameter values, displaying sensor output graphs, and displaying signs of sensor abnormalities, and can check the detection results when each sensor is operating normally and when the sensor is abnormal. It is judged that efficient device management and diagnosis is possible because it monitors abnormal data values (temperature, voltage, current) in real time and automatically diagnoses failures by feeding back the abnormal values detected at each stage. Although this algorithm cannot predict all failures related to temperature, voltage, and current of diagnostic X-ray imaging devices, it can detect temperature rise, bouncing values, device physical limits, input/output values, and radiation-related anomalies. exposure. If a value exceeding the maximum variation value of each data occurs, it is judged that it will be possible to check and respond in preparation for device failure. If a device's sensor fails, unexpected accidents may occur, increasing costs and risks, and regular maintenance cannot cope with all errors or failures. Therefore, since real-time maintenance through continuous data monitoring is possible, reliability improvement, maintenance cost reduction, and efficient management of equipment are expected to be possible.

• Journal of the Korean Society of Radiology
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• v.14 no.3
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• pp.245-252
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• 2020

The purpose of this study was intended to recognize the importance of quality control (QC) in order to reduce exposure and improve image quality by comparing the center-point (CP) of according to hospital grade and the difference between X-ray field (XF) and light field (LF) in diagnostic digital X-ray devices. XF and LF size, CP were measured in 12 digital X-ray devices at 10 hospitals located in 00 metropolitan cities. Phantom was made in different width respectively, using 0.8 mm wire after attaching to the standardized graph paper on transparent plastic plate and marked as cross wire in the center of the phantom. After placing the phantom on the table of the digital X-ray device, the images were obtained by shooting it vertically each field of survey. All images were acquired under the same conditions of exposure at distance of 100cm between the focus-detector. XF and LF size, CP error were measured using the picture archiving communication system. data were expressed as mean with standard error and then analyzed using SPSS ver. 22.0. The difference in field between the XF and LF size was the smallest in clinic, followed by university hospitals, hospitals and general hospitals. Based on the university hospitals with the least CP error, there was a statistically significant difference in CP error between university hospitals and clinics (p=0.024). Group less than 36-month after QC had fewer statistical errors than 36-month group (0.26 vs. 0.88, p=0.036). The difference between the XF and LF size was the lowest in clinic and CP error was the lowest in university hospital. Moreover, hospitals with short period of time after QC have fewer CP error and it means that introduction of timely QC according to the QC items is essential.

• Atmosphere
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• v.29 no.3
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• pp.269-282
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• 2019

While it is important to obtain the accurate information on snowfall data due to the increase in damage caused by the heavy snowfall in the winter season, it is not easy to observe the snowfall quantitatively. Recently, snow measurements using a weighing precipitation gauge have been carried out, but there is a problem that high snowfall intensity results in low accuracy. Also, the observed snowfall data are sensitive depending on wind speed, temperature, and humidity. In this study, a new process of quality control for snow water equivalent (SWE) data of the weighing precipitation gauge were proposed to cover the low accuracy of snow data and maximize the data utilization. Snowfall data (SWE) observed by Pluvio, Parsivel, snow-depth meter using laser or ultrasonic, and rainfall gauge in Cloud Physics Observation Site (CPOS) were compared and analyzed. Applying the QC algorithm including the use of number of hydrometeor particles as reference, the increased SWE per the unit time was determined and the data noise was removed and marked by flag. The SWE data converted by the number concentration of hydrometeor particles are tested as a method to restore the QC-removed data, and show good agreement with those of the weighing precipitation gauge, though requiring more case studies. The three events data for heavy snowfall disaster in Pyeongchang area was analyzed. The SWE data with improved quality was showed a good correlation with the eye-measured data ($R^2$ > 0.73).