• Archives of Pharmacal Research
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• v.23 no.2
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• pp.128-138
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• 2000

In continuation of the previous work (Fathalla, 1992) on the synthesis of some heterocycles containing uracil moiety, we report herein the incorporation of uracil moiety into cyan-opyridine thione, thiosemecarbazone, semicarbazone, cyanopyridine, ami nocyano pyridine, isoxazoline, pyrazoline, pyrimidine, triazolo pyrimidine, pyran, selena and thiazole derivatives which might modify their biological activities. The biological studies revealed that the chemical compound III f showed high molluscicdal activity than other compounds. The profile of the nucleoprotein extracted from chemically (compound IIIc, e, f and g) treated or UV-irradiated B.alexandrina snails did not show appreciable differences when compared to non-treated (native) snails by using SDS-PAGE, where no obvious qualitative or quantitative differences were observed. Immunization of experimental animals with the nucleoprotein extracted from native, chemically (compound III f ＆ g) treated or physically treated B.alexandrina snails induced significant protection against challenge with normal S.mansoni cercariae, as compared to the non-immunized challenged control. As well as , a decrease in the number of granuloma formation and the size range of granuloma was also observed in immunized animals. It is concluded that, compounds III f and g have a potent molluscicidal activity. They also induced chemical modification comparable to that induced by physical treatment in the snail's nucleoprotein, which could possibly be used in immunization against S. mansoni infection.

• The Korean Journal of Pain
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• v.34 no.3
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• pp.346-368
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• 2021

Background: Recalcitrant disc herniation may result in chronic lumbar radiculopathy or sciatica. Fluoroscopically directed epidural injections and other conservative modalities may provide inadequate improvement in some patients. In these cases, percutaneous neurolysis with targeted delivery of medications is often the next step in pain management. Methods: An evidence-based system of methodologic assessment, namely, the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) was used. Multiple databases were searched from 1966 to January 2021. Principles of the best evidence synthesis were incorporated into qualitative evidence synthesis. The primary outcome measure was the proportion of patients with significant pain relief and functional improvement (≥ 50%). Duration of relief was categorized as short-term (< 6 months) and long-term (≥ 6 months). Results: This assessment identified one high-quality randomized controlled trial (RCT) and 5 moderate-quality non-randomized studies with an application of percutaneous neurolysis in disc herniation. Overall, the results were positive, with level II evidence. Conclusions: Based on the present systematic review, with one RCT and 5 non-randomized studies, the evidence level is II for percutaneous neurolysis in managing lumbar disc herniation.

• Proceedings of the Korean Vacuum Society Conference
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• 2014.02a
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• pp.433.1-433.1
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• 2014

The research of graphene, a monolayer of carbon atoms with honeycomb lattice structure, has explosively increased after appeared in 2004. As a result, its high transmittance, mobility, thermal conductivity, and outstanding mechanical and chemical stability have been proved. Especially, many researches were executed about the field of transparent electrode highlighting material of substituting the indium tin oxide (ITO). In addition, qualitative and quantitative improvements have been achieved due to many synthesis methods were discovered. Among them, mostly used method is chemical vapour deposition of graphene grown on copper or nickel. The transmittance, mobility, sheet resistance, and other many properties are completely changed according to these two types of synthesis method of graphene. In this research, considering the difference of characteristics as the synthesis method of graphene, what types of graphene should be used and how to use it were studied. The stacked graphene harvested on copper and multi-layer graphene harvested on nickel were compared and analyzed, as a result, the transmittance of 90% and the sheet resistance of $70{\Omega}{\square}$ was showed even though stacked graphene layers were 4 layers. The reason that could bring these results is lowered sheet resistance due to stacked monolayer graphenes. Moreover, light output power of the three stacked graphene spreading layer shows the highest value, but light-emitting diode with multi-layer graphene died out from 12mA due to also its high sheet resistance. Therefore, we need to clarify about what types of graphene and how to use the graphene in use.

• Journal of Broadcast Engineering
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• v.28 no.2
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• pp.238-241
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• 2023

Recently deep learning models are widely used for various tasks such as facial recognition and face editing. Their training process often involves a dataset with imbalanced age distribution. It is because some age groups (teenagers and middle age) are more socially active and tends to have more data compared to the less socially active age groups (children and elderly). This imbalanced age distribution may negatively impact the deep learning training process or the model performance when tested against those age groups with less data. To this end, we propose an age-controllable face synthesis technique using a feature decomposition to classify age from facial images which can be utilized to synthesize novel data to balance out the age distribution. We perform extensive qualitative and quantitative evaluation on our proposed technique using the FFHQ dataset and we show that our method has better performance than existing method.

• Journal of the Korean Ceramic Society
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• v.12 no.4
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• pp.19-28
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• 1975

In order to obtain the superior refractory setter having better spalling resistance, cordierite was synthesized from domestic raw materials. Raw mixtures were fired between 125$0^{\circ}C$ and 140$0^{\circ}C$, and qualitative determination of crytallization was investigated by x-ray diffraction analysis. The results obtained are as follows; 1) The optimum batch composition of synthesized cordierite is 80.5% of Hadong kaolin (pink), 14% of Kyulsung tromolite talc and 5.5% of magnesia clinker, and the firing temperature is 1375$^{\circ}C$. 2) The composition of the refractory setter which exhibits the best values for the thermal properties is 40% of synthesized cordierite, 30% of kaolin chamotte(contains more than 60% of mullite), and 30% of Japanese clay. 3) The optimum particle size distribution of ternary mixture consists of 50% of coarse articles (3.327-1.168mm), 25% of intermediate particles (1.168-0.208mm) and 25% of fine particles (0.208-0.000mm).

• Transactions of the Korean Society of Mechanical Engineers
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• v.18 no.4
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• pp.846-855
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• 1994

An effective stiffness, analogous to that of a wound spring, can be created by antagonistic redundant actuation of general closed-chain mechanisms. The qualitative and quantitative characteristics of the effective stiffness are investigated through a Four-bar mechanism, and a load distribution method is introduced which simultaneously guarantees the required system motion and the effective stiffness of the Four-bar mechanism. Furthermore, a simulation is performed to understand the inter-relationship among the effective stiffness, the Four-bar geometry, and the actuation effort. Based on this analysis, the Four-bar synthesis problem for effective stiffness generation is discussed.

• Asia pacific journal of information systems
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• v.25 no.2
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• pp.356-369
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• 2015

Public sectors around the world utilize social media tools and technologies in their daily activities for a variety of purposes, including disseminating useful information, fostering mass collaboration, and enforcing laws and regulations. A number of social media-based government stage models have emerged to document this use. In this chapter, we conducted a qualitative meta-synthesis of four social media-based government models. These models include 1) the open government maturity model, 2) the social media utilization model, 3) the adoption process for social media, and 4) the social media-based engagement model. The concepts, metaphors, and themes contained in these developmental models are extracted through a series of in-depth semantic analyses of descriptions, resulting in a common frame of reference.

• Journal of Dairy Science and Biotechnology
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• v.23 no.2
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• pp.107-114
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• 2005

The trend towards ageing populations has been observed over many years in Europe and the US but has accelerated significantly in developed countries in Asia including Japan and South Korea. In the latter country the elderly population (65+) has increased 5-fold between 1960 and 2000 and this group will comprise 40% of the population by 2050. This creates a new socio-economic group with specific demands and considerable spending power. As ageing occurs a range of changes occur in the body that can be moderated by adjustments in nutrition. A significant body of evidence points to changes in the balance of glutathione synthesis and utilisation as people age. Glutathione is tile most important natural anti-oxidant of the body and the amounts present can become limited by available cysteine in the diet. A cysteine-enriched peptide product, Cysteine Peption$^{TM}$ has been developed by DMV International for dietary supplement and food applications. A qualitative consumer trial has indicated benefits including improved sleep and more energy. Animal and clinical trial will be described that provide indications on bioavailability and possible mechanisms of action of Cysteine Peption$^{TM}$ with particular focus on the ageing population.

• Journal of Korean Elementary Science Education
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• v.19 no.1
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• pp.71-83
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• 2000

This study examined the influences of science project activities based on multiple intelligences on problem solving behaviors of elementary school children. Specifically, the influences of the project activities on the problem solving skills and propensities of the children were investigated. Forty-four fifth graders were selected for the study. They performed the projects and made their products of it during five months on the units of "Weather" and "Our Body" Criteria for assessment of problem solving abilities were determined. The patterns reflected in products of the project activities were examined, then the observation of the subjects' problem solving behaviors and the interviews were performed based on the criteria. The results were analyzed through both of qualitative and quantitative approaches. In these analyses, the implementation of the science projects was found to contribute to the improvement in all sub-factors of problem solving, specially, skills associated with the propensities of problem identification and of the collection, analysis, and synthesis of data significantly increased

• Journal of The Korean Astronomical Society
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• v.31 no.2
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• pp.77-87
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• 1998

The accumulated knowledge of the influence of solar granulation on spectral lines, i.e. their asymmetry, provides a key to analyze stellar spectral line asymmetries. In this paper, a simple line synthesis using a simple 'model' of granulation was calculated. By adjusting the properties of the granule model, the observed imprints of convection on spectral lines can be reproduced. Since we depict convective flows using a continuous function rather than using a few components of flows (cf. Gray and Toner 1985, 1986; dravins 1990), we were able to identify which components of convection are important in line bisector shapes. The results of this study can be summarized as follows: Firstly, the intensity contrast (i.e. temperature fluctuation), and the area coverage of up- and down-flows are the two important factors which determine the line bisector shapes. Secondly, on the contrary to the assumption of other studies, the effect of horizontal flows is non-negligible. This exercise provides a qualitative understanding of the effect of convection on spectral lines. This knowledge serves as a guideline for understanding the characteristic difference in convection for stars on either side of the 'Granulation Boundary' (Gray 1982; Gray and Nagel 1989).