• 산업융합연구
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• 제18권5호
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• pp.97-101
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• 2020

이 연구는 초등학생 대상 파이썬 활용 교육의 효과를 메타분석을 통해 분석하기 위해 실시되었다. 연구를 위해 파이썬을 활용하여 교육을 실시한 후 효과에 관해 보고한 선행연구 논문 5편을 선정하여 분석하였다. 설정된 연구문제는 다음과 같다. 전체 효과크기는 무엇인가? 출판 여부, 종속변인 유형 등의 범주형 변인에 따른 효과크기는 무엇인가? 학년, 운영기간 등의 연속형 변인에 따른 효과크기는 무엇인가? 연구 결과로써 파이썬 활용 교육의 전체 효과크기는 중간 효과인 .598로 나타났다. 범주형 변수에 따라, 출판된 연구물의 효과크기가 학위 논문보다, 정의적 영역의 효과크기가 학업성취도, 인지적 영역 보다 효과크기가 큰 것으로 나타났다. 메타회귀분석 결과 교육 운영기간이 길수록, 프로그램 운영시간이 클수록 더 큰 효과가 나타났다. 마지막으로 논의 및 정의적 영역에 대한 질적 탐색, 프로그램 특징을 고려한 운영 등을 중심으로 제언을 제시하였다.

• Physical Therapy Rehabilitation Science
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• 제12권2호
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• pp.115-122
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• 2023

Objective: A previous study reported that cardiovascular training (CT) decreased interleukin-6 (IL-6), a pro-inflammatory cytokine with bidirectional effects. However, because of conflicting results of increasing and decreasing IL-6 levels in stroke patients, it is essential to clarify the effects of CT on IL-6 levels in this population. Therefore, this review aimed to investigate the effects of CT on IL-6 levels in stroke patients through a meta-analysis of randomized controlled trials (RCTs), synthesizing and analyzing the effects qualitatively and quantitatively. Design: A systematic review and meta-analysis of randomized controlled trials. Methods: In this review, conducted in April 2023, electronic databases (Web of Science, CINAHL, Embase, MEDLINE, Google Scholar) were searched to ascertain the effects of CT on IL-6 levels in stroke patients. For qualitative evaluation, ReVMan, provided by the Cochrane Group, was used, and for quantitative evaluation, a random-effects model and SMD (Standardized Mean Difference) were used. Results: Three RCTs measured IL-6 in 117 patients with stroke. The experimental group to which CT was applied showed no significant change compared to the control group.The result of analysis using the random effect model is SMD=-0.23; 95% confidence interval, -0.66 to 0.20. Conclusions: CT does not affect IL-6 levels in stroke patients. These results suggest that CT can be applied regardless of its positive or negative effect on IL-6 levels in stroke patients.

• Asian Pacific Journal of Cancer Prevention
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• 제16권11호
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• pp.4665-4669
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• 2015

The aim of this study was to assess the diagnostic value of RASSF1A methylation in renal cell carcinoma. Systematically search were performed using the Pubmed, ProQest and Web of Science for all articles on the association between RASSF1A methylation and renal cell carcinoma before 15 April 2015. After the filtration, 13 studies involving 677 cases and 497 controls met our criteria. Our meta-analysis suggested that hypermethylation of RASSF1A gene was associated with the increased risk of RCC(OR:4.14, 95%CI:1.06-16.1). Stratified analyses showed a similar risk in qualitative detection method(OR:28.4, 95%CI:10.2-79.6), body fluid sample(OR:12.8, 95%CI:5.35-30.8), and American(OR:10.5, 95%CI:1.97-55.9). Our result identified that RASSF1A methylation had a strong potential in prediction the risk of Renal cell carcinoma.

• Physical Therapy Rehabilitation Science
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• 제12권1호
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• pp.12-18
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• 2023

Objective: Chemotherapy is usually given to inhibit cancer progression. It is the most common side effect of chemotherapyinduced peripheral neuropathy (CIPN) after chemotherapy, and its symptoms include pain such as paresthesia, dysesthesia, allodynia, hyperalgesia, and electrical stimulation. Therefore, in this review, randomized controlled trials (RCTs) were combined to analyze the effect qualitatively and quantitatively in order to find out the effect of manual therapy on patients with CIPN through a meta-analysis. Design: A systematic review and meta-analysis Methods: This review conducted a literature search through international databases (CINAHL, Embase, MEDLINE, Web of Science) in December 2022 to synthesize the effect of manual therapy on the symptomatic improvement of CIPN. Qualitative evaluation (risk of bias) and quantitative evaluation using ReVMan provided by the Cochrane Group were expressed as a random effect model and standardized mean difference (SMD). Results: In four RCTs 165 patients with CIPN were evaluated for symptoms of neuropathy. The experimental group consisting of manual therapy and its subcategories showed significant improvement compared to the control group. The results analyzed through the random effects model were SMD=-1.11; 95% confidence interval, -1.97 to -0.24. Conclusions: We came to the conclusion that manual therapy could significantly contribute to improving the symptoms of CIPN, and since it may vary depending on the technique of manual therapy, further studies on manual therapy suitable for neuropathy are needed.

• 한국초등과학교육학회지:초등과학교육
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• 제42권3호
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• pp.434-454
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• 2023

본 연구는 초등교육 현장에서 이루어진 모델링 수업 사례와 모델링 수업에 관한 초등교사의 인식이 나타난 연구를 통해 초등과학 모델링 수업의 구성과 속성 및 교사의 역량 요인을 탐색하고자 하였다. 이를 위해 모델링 수업 사례와 초등교사의 인식이 드러난 질적 연구물을 종합적으로 분석하는 질적 메타분석을 수행하였다. 분석 결과, 초등과학 모델링 수업의 구성은 모델을 생성하고 평가한 뒤 수정하는 과정을 거치며, 이러한 과정은 소집단 상호작용 안에서 이루어짐을 알 수 있었다. 초등과학 모델링 수업의 속성은 모델링 수업에 영향을 미치는 요인과 모델링 수업에 참여하는 학생에게 요구되는 역량 요인으로 나뉠 수 있는데, 모델링 수업에 영향을 미치는 요인에는 '소집단 상호작용'과 '수업 시간'이 도출되었다. 모델링 수업에 참여하는 학생들에게 요구되는 역량 요인으로는 '과학 지식', '메타모델링 지식', '감정 조절 능력'이 도출되었다. 초등과학 모델링 수업에 필요한 교사의 역량 요인은 교사가 알아야 할 지식, 갖추어야 할 기능, 태도 측면에서 분석되었다. 분석 결과, 교사는 '메타모델링 지식', '모델링 평가지식'을 알고 있어야 하며, '학생에 대한 감정적 지원' 능력을 갖추고, '모델링의 가치에 대해 인식'하는 것이 필요함을 알 수 있었다. 이러한 분석 결과를 바탕으로 본 연구에서는 효과적인 모델링 수업을 위한 교육적 방법에 대해 논의하였다.

• 과학교육연구지
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• 제45권1호
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• pp.11-22
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• 2021

이 연구의 목적은 국제 STEM 교육 분야의 연구 결과를 종합하여 국제 STEM 교육의 주요 이슈를 파악하는 데 있다. 이 연구의 분석 대상 자료는 선정 기준과 전문가 그룹의 검토를 통해 다양한 STEM 교육의 이슈를 반영하고 있는 메타분석 또는 체계적 문헌연구의 결과이다. 총 23개의 연구를 대상으로 질적 메타 분석을 하여 다음과 같은 STEM 교육의 이슈를 선정하였다. 첫째, STEM 교육은 국제적인 교육 동향으로 미국, 캐나다, 호주, 한국, 터키 등 많은 국가에서 연구되고 있다. 둘째, STEM 교육은 학생들의 인지적, 정의적, 심동적, 그리고 진로 영역의 향상에 긍정적으로 기여하고 있다. 셋째, STEM 교육은 다양한 수업 도구와 기술의 사용과 함께 연구되어 왔다. 또한, STEM 교육에 대한 교사의 전문성 신장이 성공적인 STEM 교육의 실현의 주요 요인들 중 하나이다. 그 외에 STEM 교육의 성공적인 실천을 위해 다양성, 평등, 타당하고 신뢰로운 연구 설계 등의 이슈에 대해 논의하였다. 또한 이 연구는 우리나라 융합교육의 방향과 실천 전략을 위한 함의점을 제공할 수 있으며 향후 연구에 대한 제언을 줄 수 있다.

• 산경연구논집
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• 제14권1호
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• pp.49-56
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• 2023

Purpose: This research aims to explore the impact of fashion marketing on the sales of luxury brand items and to identify the strategies that can be used to market luxury fashion items successfully, addressing the research gap of how fashion marketing can lead to increased sales, customer loyalty, and satisfaction for luxury brand items. Research design, data and methodology: The present study conducted the method of the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) which is a reporting guideline for methodical assessments and meta-analyses. It offers a consistent approach for conducting and reporting these types of studies, which can help to improve their quality and transparency. Results: The findings indicated that fashion marketing can positively impact luxury brand sales. It can significantly increase the number of luxury brand purchases. the presence of the quality label increased the participants' purchase intention and attitude towards the brand, suggesting that the quality label can create a positive perception of the brand and increase the likelihood of purchasing. Conclusions: This research concludes that fashion marketing can have a positive effect on improved customer recognition of the brand. Thus, companies should focus on developing campaigns that capture the attention of potential consumers, creating an emotional connection with them.

• The Korean Journal of Pain
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• 제34권3호
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• pp.346-368
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• 2021

Background: Recalcitrant disc herniation may result in chronic lumbar radiculopathy or sciatica. Fluoroscopically directed epidural injections and other conservative modalities may provide inadequate improvement in some patients. In these cases, percutaneous neurolysis with targeted delivery of medications is often the next step in pain management. Methods: An evidence-based system of methodologic assessment, namely, the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) was used. Multiple databases were searched from 1966 to January 2021. Principles of the best evidence synthesis were incorporated into qualitative evidence synthesis. The primary outcome measure was the proportion of patients with significant pain relief and functional improvement (≥ 50%). Duration of relief was categorized as short-term (< 6 months) and long-term (≥ 6 months). Results: This assessment identified one high-quality randomized controlled trial (RCT) and 5 moderate-quality non-randomized studies with an application of percutaneous neurolysis in disc herniation. Overall, the results were positive, with level II evidence. Conclusions: Based on the present systematic review, with one RCT and 5 non-randomized studies, the evidence level is II for percutaneous neurolysis in managing lumbar disc herniation.

• Restorative Dentistry and Endodontics
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• 제47권3호
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• pp.30.1-30.15
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• 2022

Objectives: This study aimed to evaluate the effectiveness of final irrigation with cold saline solution after endodontic treatment compared with saline solution at room temperature against postoperative pain following endodontic treatment. Materials and Methods: A broad search was performed in the PubMed, Web of Science, Scopus, Cochrane Library, Virtual Health Library (LILACS), and Grey Literature databases. Two independent reviewers performed data extraction, risk of bias using the Cochrane methodology, and certainty of evidence using the Grading of Recommendations, Assessment, Development and Evaluations (GRADE) approach. Results: Eight studies were included in qualitative synthesis. Intracanal cryotherapy favored the reduction of postoperative pain in the systematic review. Four studies were included in meta-analyses. The meta-analysis showed that intracanal cryotherapy reduced postoperative pain in teeth with symptomatic apical periodontitis (SAP) at 24 hours. There was no association between intracanal cryotherapy and control (room temperature) groups in teeth with normal periapical tissue with respect to postoperative pain at 24 hours and 48 hours. Conclusions: Intracanal cryotherapy was effective in reducing postoperative pain after endodontic treatment in teeth with SAP.

• Journal of Periodontal and Implant Science
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• 제52권5호
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• pp.352-369
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• 2022

The aim of this systematic review was to evaluate clinical and microbiological outcomes with the use of azithromycin as an adjunct to non-surgical subgingival professional mechanical plaque removal (PMPR) in the treatment of grade C periodontitis. Online database searches using high-level MeSH terms in a PICO structure were conducted along with hand-searching of relevant periodontal journals. Titles and abstracts of identified studies were independently reviewed by both authors and the full texts of studies meeting the inclusion criteria were independently reviewed. In total, 122 studies were identified through searches, of which 6 were included in the qualitative analysis and 4 in the meta-analysis. Three studies included in the meta-analysis were deemed at low risk of bias and 1 at serious risk. There were conflicting results on whether azithromycin reduced the number of subgingival pathogens or detectable subgingival Aggregatibacter actinomycetemcomitans between the included studies. The meta-analysis revealed a statistically significant probing depth reduction difference in favour of azithromycin compared to the control at 3 months (weighted mean difference [WMD]=-0.39 mm; 95% confidence interval [CI], -0.66 to -0.13 mm; I²=0%) and 12 months (WMD=-1.32 mm; 95% CI, -1.71 to -0.93 mm; I²=0%). The clinical attachment level change was also statistically significant in favour of azithromycin compared to the control at 3 months (WMD=-0.61 mm; 95% CI, -1.13 to -0.10 mm; I²=71%) and 12 months (WMD=-0.88 mm; 95% CI, -1.32 to -0.44 mm; I²=0%). Based upon these results, azithromycin offers additional improvements in some clinical parameters when used in conjunction with subgingival PMPR in patients with aggressive periodontitis over control groups. These improvements appear to be maintained for up to 12 months after treatment completion. However, due to a lack of well-designed studies, the conclusions that can be drawn from the available evidence are limited.