• Journal of the Korean Statistical Society
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• v.16 no.2
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• pp.71-79
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• 1987

The linear and quadratic log contrast model with mixtures on the strictly positive simplex, $$ x_{q-1} = {(x_1, \cdots, x_q):\sum x_, = 1 and \delta \leq \frac{x_i}{x_j} \leq \frac{1}{\delta} for all i,j},$$ are considered. Using the invariance arguments, symmetric D-optimal designs are investigated. The class of symmetric D-optimal designs for the linear log contrasts model is given. Any D-optimal design for the quadratic log contrast model is shown to metric D-optimal designs for q=3 and 4 cases are given.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.26 no.1
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• pp.58-63
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• 2022

The daily number of confirmed cases of Coronavirus disease 2019(COVID-19) ranges between 1,000 and 2,000. Despite higher vaccination rates, the number of confirmed cases continues to increase. The Mu variant of COVID-19 reported in some countries by WHO has been identified in Korea. In this study, we predicted the number of confirmed COVID-19 cases in Korea using the SARIMA for the Covid-19 prevention strategy. Trends and seasonality were observed in the data, and the ADF Test and KPSS Test was used accordingly. Order determination of the SARIMA(p,d,q)(P, D, Q, S) model helped in extracting the values of p, d, q, P, D, and Q parameters. After deducing the p and q parameters using ACF and PACF, the data were transformed and schematized into stationary forms through difference, log transformation, and seasonality removal. If seasonality appears, first determine S, then SARIMA P, D, Q, and finally determine ARIMA p, d, q using ACF and PACF for the order excluding seasonality.

• Electronics and Telecommunications Trends
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• v.30 no.1
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• pp.154-161
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• 2015

본고에서는 Q-mark 모델의 R&D(Research & Development) 품질 영향 분석을 기술한다. 이를 위해 Q-mark 모델 특징과 종류 그리고 절차를 간략히 기술하고, R&D 품질에 대한 Q-mark 인증 모델 영향에 대해 연구현장 설문조사 내용을 바탕으로 연구결과 완성도 측면, 대외 신뢰도 개선을 통한 과제 수주 측면, 기술 이전과 사업화 측면, 그리고 과제관리 효율화 측면 등에서 분석하여 제시한다. 또 앞으로 Q-mark 모델이 보다 객관적이고 효과적인 R&D 품질관리를 위한 인증 모델로 개선되고 지속적으로 운영되기 위해 보완되어야 할 사항에 대해 설문조사 결과를 바탕으로 인증 측면, 프로세스 범주 측면, 제공 템플릿 측면, 그리고 품질 지원 서비스 및 전문성 측면에서 기술한다.

• Geophysics and Geophysical Exploration
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• v.10 no.3
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• pp.191-202
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• 2007

To identify the detailed attenuation structure in the southern Korean Peninsula, a numerical test was conducted for the Q tomography inversion to be applied to the accumulated dataset until 2005. In particular, the stochastic pointsource ground-motion model (STGM model; Boore, 2003) was adopted for the 2D Q tomography inversion for direct application to simulating the strong ground-motion. Simultaneous inversion of the STGM model parameters with a regional single Q model was performed to evaluate the source and site effects which were necessary to generate an artificial dataset for the numerical test. The artificial dataset consists of simulated Fourier spectra that resemble the real data in the magnitude-distance-frequency-error distribution except replacement of the regional single Q model with a checkerboard type of high and low values of laterally varying Q models. The total number of Q blocks used for the checkerboard test was 75 (grid size of $35{\times}44km^2$ for Q blocks); Q functional form of $Q_0f^{\eta}$ ($Q_0$=100 or 500, 0.0 < ${\eta}$ < 1.0) was assigned to each Q block for the checkerboard test. The checkerboard test has been implemented in three steps. At the first step, the initial values of Q-values for 75 blocks were estimated. At the second step, the site amplification function was estimated by using the initial guess of A(f) which is the mean site amplification functions (Yun and Suh, 2007) for the site class. The last step is to invert the tomographic Q-values of 75 blocks based on the results of the first and second steps. As a result of the checkerboard test, it was demonstrated that Q-values could be robustly estimated by using the 2D Q tomography inversion method even in the presence of perturbed source and site effects from the true input model.

• Proceedings of the KSME Conference
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• 2002.08a
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• pp.623-626
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• 2002

The object of present study is to find the flow characteristics of centrifugal turbomachinery according to the volute shape change. The experiments were carried out for two model; volute-A designed by free vortex conditions and volute-B designed for use in high mass flow rate conditions using the volute-A test results, Flow measurements were taken in shrouded impeller with 12 backward type blades by using a five-hole pilot-tube and carried out in 4 flow rate, $Q/Q_d\;=0,43,\;1.0,\;1.27,\;1,47$, respectively, For volute-B, we found that pressure distribution was more uniform at high flow rate and from $Q/Q_d\;:\;0,43\;to\;Q/Q_d\;:\;1,20$, losses decreased and efficiency increased compare with volute-A.

• Korean Journal of Radiology
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• v.20 no.4
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• pp.641-648
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• 2019

Objective: The purpose of this study was to investigate whether three-dimensional (3D) magnetic resonance imaging could improve diagnostic accuracy for suspected posterior ligamentous complex (PLC) disruption. Materials and Methods: We used 20 freshly harvested goat spine samples with 60 segments and intact surrounding soft tissue. The animals were aged 1-1.5 years and consisted of 8 males and 12 females, which were sexually mature but had not reached adult weights. We created a paraspinal contusion model by percutaneously injecting 10 mL saline into each side of the interspinous ligament (ISL). All segments underwent T2-weighted sagittal and coronal short inversion time inversion recovery (STIR) scans as well as coronal and sagittal 3D proton density-weighted spectrally selective inversion recovery (3D-PDW-SPIR) scans acquired at 1.5T. Following scanning, some ISLs were cut and then the segments were rescanned using the same magnetic resonance (MR) techniques. Two radiologists independently assessed the MR images, and the reliability of ISL tear interpretation was assessed using the kappa coefficient. The chi-square test was used to compare the diagnostic accuracy of images obtained using the different MR techniques. Results: The interobserver reliability for detecting ISL disruption was high for all imaging techniques (0.776-0.949). The sensitivity, specificity, and diagnostic accuracy of the coronal 3D-PDW-SPIR technique for detecting ISL tears were 100, 96.9, and 97.9%, respectively, which were significantly higher than those of the sagittal STIR (p = 0.000), coronal STIR (p = 0.000), and sagittal 3D-PDW-SPIR (p = 0.001) techniques. Conclusion: Compared to other MR methods, coronal 3D-PDW-SPIR provides a more accurate diagnosis of ISL disruption. Adding coronal 3D-PDW-SPIR to a routine MR protocol may help to identify PLC disruptions in cases with nearby contusion.

• Advances in aircraft and spacecraft science
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• v.9 no.5
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• pp.479-491
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• 2022

This work concerns the investigation of a Q1D methodology employed to study pressure oscillations in solid rocket motors driven by hydrodynamic instabilities. A laboratory-scale solid motor designed to develop vortex-shedding phenomena is analyzed for the whole firing time. The comparison between numerical results and experimental data shows good agreement regarding pressure oscillations signature, especially in the flute-mode behavior, the typical oscillations frequency trend present in any motor liable to hydrodynamic instabilities. Such result ensures the model capability to cope with this particular kind of pressure oscillations source, allowing the investigation of the phenomenon with a lighter and cost savings methodology than CFD simulations.

• Biotechnology and Bioprocess Engineering:BBE
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• v.11 no.1
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• pp.61-66
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• 2006

The simple Langmuir isotherm is frequently employed to describe the equilibrium behavior of protein adsorption on a wide variety of adsorbents. The two adjustable parameters of the Langmuir isotherm - the saturation capacity, or $q_m$, and the dissociation constant, $K_d$ - are usually estimated by fitting the isotherm equation to the equilibrium data acquired from batch equilibration experiments. In this study, we have evaluated the possibility of estimating $q_m$ and $K_d$ for the adsorption of bovine serum albumin to a cation exchanger using batch kinetic data. A rate model predicated on the kinetic form of the Langmuir isotherm, with three adjustable parameters ($q_m,\;K_d$, and a rate constant), was fitted to a single kinetic profile. The value of $q_m$ determined as the result of this approach was quantitatively consistent with the $q_m$ value derived from the traditional batch equilibrium data. However, the $K_d$ value could not be retrieved from the kinetic profile, as the model fit proved insensitive to this parameter. Sensitivity analysis provided significant insight into the identifiability of the three model parameters.

• Korean Journal of Mathematics
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• v.22 no.1
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• pp.29-36
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• 2014

The limiting diffusion of special diploid model can be defined as a discrete generator for the rescaled Markov chain. Choi([2]) defined the operator of projection $S_t$ on limiting diffusion and new measure $dQ=S_tdP$. and showed the martingale property on this operator and measure. Let $P_{\rho}$ be the unique solution of the martingale problem for $\mathcal{L}_0$ starting at ${\rho}$ and ${\pi}_1,{\pi}_2,{\cdots},{\pi}_n$ the projection of $E^n$ on $x_1,x_2,{\cdots},x_n$. In this note we define $$dQ_{\rho}=S_tdP_{\rho}$$ and show that $Q_{\rho}$ solves the martingale problem for $\mathcal{L}_{\pi}$ starting at ${\rho}$.

• Journal of Biomedical Engineering Research
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• v.43 no.1
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• pp.19-26
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• 2022

The Comprehensive in vitro Proarrhythmic Assay(CiPA) project was launched for solving the hERG assay problem of being classified as high-risk groups even though they are low-risk drugs due to their high sensitivity. CiPA presented a protocol to predict drug toxicity using physiological data calculated based on the in-silico model. in this study, features calculated through the in-silico model are analyzed for correlation of changing action potential in the near future, and features are verified through predictive performance according to drug datasets. Using the O'Hara Rudy model modified by Dutta et al., Pearson correlation analysis was performed between 13 features(dVm/dtmax, APpeak, APresting, APD90, APD50, APDtri, Ca_peak, Ca_resting, CaD90, CaD50, CaDtri, qNet, qInward) calculated at 100 pacing, and between dVm/d_{tmax_repol} calculated at 1,000 pacing, and linear regression analysis was performed on each of the 12 training drugs, 16 verification drugs, and 28 drugs. Indicators showing high coefficient of determination(R²) in the training drug dataset were qNet 0.93, AP resting 0.83, APDtri 0.78, Ca resting 0.76, dVm/dt_max 0.63, and APD90 0.61. The indicators showing high determinants in the validated drug dataset were APDtri 0.94, APD90 0.92, APD50 0.85, CaD50 0.84, qNet 0.76, and CaD90 0.64. Indicators with high coefficients of determination for all 28 drugs are qNet 0.78, APD90 0.74, and qInward 0.59. The indicators vary in predictive performance depending on the drug dataset, and qNet showed the same high performance of 0.7 or more on the training drug dataset, the verified drug dataset, and the entire drug dataset.