• Title/Summary/Keyword: Q10

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The Effect of coenzyme QI0 Supplement On Cardiorepiratory Function and the Energy Substrates Utilization During Maximal Exercise

  • Kim, Jun-Mo
    • Journal of the Korean Data and Information Science Society
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    • v.19 no.4
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    • pp.1091-1100
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    • 2008
  • The purpose of this study is to find out how energy substrate's utilizations in the maximal exercise-cardiorespiratory function and the energy metabolic variation- have the effect on before and after the supplements of coenzyme Q10(100mg per day for 8 weeks) based on the male students(CoQ10=8, placebo=8) of high school. The results of this study are as follows: Maximal oxygen uptake and maximal oxygen per weight are found to have the significant increase respectively in supplement group. Glucose is found to have the significant decrease after the supplement of CoQ10. And then FFA is found to have the significant increase. In the above results, the supplements of CoQ10 and cardiorespiratory function in the maximal exercise are found to have the improvement. CoQ10 in the anaerobic exercise spares the energy's utilization of Glucose and then is found to have the increase of the utilization of FFA. CoQ10 in the aerobic exercise is reported to have the increase of the utilization of FFA and then CoQ10 in the maximal exercise is also recognized to have the increase of the utilization of FFA, or energy substrates.

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Injury Study for Q6 and Q10 Child Dummies (Q6, Q10 어린이 인체모형의 상해치 연구)

  • Sun, Hongyul;Lee, Seul;Seok, Juyup;Yoo, Wonjae;Yoon, Ilsung
    • Journal of Auto-vehicle Safety Association
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    • v.8 no.1
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    • pp.31-37
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    • 2016
  • The Child Occupant Safety Assessment was first introduced and carried out by Euro NCAP in 2003, with the goal of ensuring manufacturers to develop safe vehicles for passengers of all ages; the objective was to evaluate the safety and protection offered by different Child Restraint Systems (CRS) in the event of a crash. In 2013, the formerly used P child dummy series was replaced by newer and more biofidelic Q1.5 and Q3 child dummies, representing 1.5 and 3 year old children respectively. The frontal and side impact dynamic performances of the Q1.5 and Q3 were tested within all classes of vehicles assessed by Euro NCAP at the time. As an extension to that initiative, Q6 and Q10 child dummies were later developed representing children of 6 and 10 years old. Since the protection of larger children during vehicle crashes relies greatly on the interaction of vehicle restraint systems such as seat belt and the CRS, instrumented Q6 and Q10 dummies will be used to assess the protection offered in the event of front and side impact crashes. In this paper, we focused on injury criteria of Q6 and Q10 child dummies at 64 kph 40% offset frontal crash test. The whole procedure was designed with DFSS analysis. The full vehicle sled test results of both dummies were conducted with different restraint systems settled through previous sled test. It showed that several injury criteria and image data were collected as the result of the full vehicle sled test. Based on the results of these investigations, this paper describes which factor is most important and combination shows the best performance when evaluating rear seat occupant protection for Q6 and Q10 child dummies.

Coenzyme $Q_{10}$ Production by Sphingomonas sp. ZUTE03 with Novel Precursors Isolated from Tobacco Waste in a Two-Phase Conversion System

  • Qiu, Lequan;Wang, Weijian;Zhong, Weihong;Zhong, Li;Fang, Jianjun;Li, Xuanzhen;Wu, Shijin;Chen, Jianmeng
    • Journal of Microbiology and Biotechnology
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    • v.21 no.5
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    • pp.494-502
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    • 2011
  • Coenzyme $Q_{10}$ ($CoQ_{10}$) is a widely used supplement in heart diseases treatment or antioxidative dietary. The microbial production of $CoQ_{10}$ was enhanced by addition of solanesol and novel precursors recovered from waste tobacco. The novel precursors were separated by silica gel and identified as ${\alpha}$-linolenic acid (LNA) and butylated hydroxytoluene (BHT) based on the effect on $CoQ_{10}$ production and GC-MS. The effects of novel precursors on $CoQ_{10}$ production by Sphingomonas sp. ZUTE03 were further evaluated in a two-phase conversion system. The precursor's combination of solanesol (70 mg/l) with BHT (30 mg/l) showed the best effect on the improvement of $CoQ_{10}$ yield. A maximal $CoQ_{10}$ productivity (9.5 mg $l^{-1}$ $h^{-1}$) was achieved after 8 h conversion, with a molar conversion rate of 92.6% and 92.4% on BHT and solanesol, respectively. The novel precursors, BHT and LNA in crude extracts from waste tobacco leaves, might become potential candidates for application in the industrial production of $CoQ_{10}$ by microbes.

Bioaccessibility of β-Lactoglobulin Nanoemulsions Containing Coenzyme Q10: Impact of Droplet Size on the Bioaccessibility of Coenzyme Q10

  • Ha, Ho-Kyung;Lee, Mee-Ryung;Lee, Won-Jae
    • Food Science of Animal Resources
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    • v.38 no.6
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    • pp.1294-1304
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    • 2018
  • The aims of this research were to examine the effect of heating temperature (65, 75, and $85^{\circ}C$) and $CaCl_2$ concentration level (3, 4, and 5 mM) on the physicochemical properties of ${\beta}$-lactoglobulin (${\beta}$-lg) nanoemulsions (NEs) and to study how the droplet size of NEs affects the bioaccessibility (BA) of coenzyme $Q_{10}$ ($CoQ_{10}$). The droplet size of NEs and BA of $CoQ_{10}$ was assessed by particle size analyzer and UV-Vis spectrophotometer, respectively. An increase in heating temperature and $CaCl_2$ concentration level resulted in a significant (p<0.05) increase in the droplet size of NEs while there were no significant differences in polydispersity index and zeta-potential of NEs. When NEs containing $CoQ_{10}$ were incubated in simulated small intestinal phases, an increase in the droplet size and polydispersity index of NEs was observed. This indicated that NEs were not stable in small intestine and digestion of NEs occurred. As heating temperature and $CaCl_2$ concentration level were decreased, a significant (p<0.05) increase in BA of $CoQ_{10}$ was observed. There was a significant (p<0.05) increase in BA of $CoQ_{10}$ with a decrease in the droplet size of NEs. In conclusion, heating temperature and $CaCl_2$ concentration level were key-parameters affecting the initial droplet size of NEs and BA of $CoQ_{10}$ was negatively correlated with initial droplet size of NEs.

The Effects of Coenzyme Q10 Supplementation on Oxidative Status and Lipid Profile in Migraine Patients: A Randomized Double-Blinded Controlled Clinical Trial

  • Monireh Dahri;Atefeh Sarafan Sadeghi;Naseh Pahlavani;Elyas Nattagh-Eshtivani;Mazyar Hashemilar;Mohammad Asghari-Jafarabadi;Hanieh Barghchi;Ali Tarighat-Esfanjani
    • Clinical Nutrition Research
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    • v.12 no.4
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    • pp.257-268
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    • 2023
  • Migraine is a common neurological disease correlated with oxidative stress and lipid profile disorders. The present study was designed to determine the effects of Coenzyme Q10 (Co-Q10) supplementation on oxidative status and lipid profile in migraine individuals. This clinical trial was conducted on 84 females aged 18-50 years, diagnosed for episodic migraine according to the International Headache Society. Subjects were randomized to receive either Co-Q10 supplement (400 mg/day) or placebo for 12 weeks. Lipid profile and oxidative stress indices including malondialdehyde (MDA) and total antioxidant capacity (TAC) were measured before and after intervention in both groups. Also, anthropometric indices, dietary intakes, and clinical features were collected. Data analysis was conducted using SPSS version 16. Seventy-seven of the participants, with mean age of 33.70 ± 7.75 years, completed the study. After 12-week intervention, Co-Q10 led to a significant decrease in MDA levels compared to placebo (p = 0.009), with no effect on TAC levels (p = 0.106). A significant increase in serum Co-Q10 concentration and high-density lipoprotein cholesterol (HDL-C) level in Co-Q10 group was observed, but no significant differences were found in other lipid profile variables (low-density lipoprotein cholesterol, triglycerides and total cholesterol). Among anthropometric variables, Co-Q10 only caused a significant reduction in body fat percentage (BFP), but we did not find any significant changes in others. A 12-week Co-Q10 supplementation led to significant improvement in clinical features, BFP, and HDL-C level among migraine individuals.

LITTLE HANKEL OPERATORS ON WEIGHTED BLOCH SPACES IN Cn

  • Choi, Ki-Seong
    • Communications of the Korean Mathematical Society
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    • v.18 no.3
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    • pp.469-479
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    • 2003
  • Let B be the open unit ball in $C^{n}$ and ${\mu}_{q}$(q > -1) the Lebesgue measure such that ${\mu}_{q}$(B) = 1. Let ${L_{a,q}}^2$ be the subspace of ${L^2(B,D{\mu}_q)$ consisting of analytic functions, and let $\overline{{L_{a,q}}^2}$ be the subspace of ${L^2(B,D{\mu}_q)$) consisting of conjugate analytic functions. Let $\bar{P}$ be the orthogonal projection from ${L^2(B,D{\mu}_q)$ into $\overline{{L_{a,q}}^2}$. The little Hankel operator ${h_{\varphi}}^{q}\;:\;{L_{a,q}}^2\;{\rightarrow}\;{\overline}{{L_{a,q}}^2}$ is defined by ${h_{\varphi}}^{q}(\cdot)\;=\;{\bar{P}}({\varphi}{\cdot})$. In this paper, we will find the necessary and sufficient condition that the little Hankel operator ${h_{\varphi}}^{q}$ is bounded(or compact).

Varietal Differences in Growth and Development Affected by Temperature in Barley (대맥품종의 오도에 따른 생육반응)

  • 천종은;박문웅;김정곤;이은섭
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.33 no.4
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    • pp.343-349
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    • 1988
  • In order to get informations for breeding early barley cultivars, the thermosensitivity and low temperature growth ability about the breeding materials vernalized were tested at the high '||'&'||'amp; low temperature and field conditions. The temperature coefficient (Q10), ratio and thermosensitivity for plant height were various among cultivars versus temperature treatments. The early cultivars had greater Q10 values and insensitive responses to temperature changes. The Q10 and thermosensitivity for the time of flag leaf unfolding were various among cultivars, but the coefficient of variation in the thermosensitivity was greater, so the character would be more useful for investigating the varietal differences. The Q10 and thermosensitivity for plant height were not significantly correlated with Q10 and thermosensitivity for the time of flag leaf unfolding. The periods from heading to flowering were 2 to 4 days at the high temperature plot, but 1 to 11 days at the low temperature plot, showing much greater variations. In general the cultivars with greater difference of heading time between the high and low temperature plots were Suwon 218, SB 76588, Oweolbori, and Jogangbori, showing the sensitive thermophase and early heading.

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