• Sleep Medicine and Psychophysiology
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• v.28 no.2
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• pp.78-85
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• 2021

Objectives: When elderly patients show depressive symptoms, discrimination between depressive disorder and prodromal phase of Alzheimer's disease is important. We tested whether a quantitative electroencephalogram (qEEG) marker was associated with cerebral amyloid-β (Aβ) deposition in older adults with depression. Methods: Non-demented older individuals (≥ 55years) diagnosed with depression were included in the analyses (n = 63; 76.2% female; mean age ± standard deviation 73.7 ± 6.87 years). The participants were divided into Aβ+ (n = 32) and Aβ- (n = 31) groups based on amyloid PET assessment. EEG was recorded during the 7min eye-closed (EC) phase and 3min eye-open (EO) phase, and all EEG data were analyzed using Fourier transform spectral analysis. We tested interaction effects among Aβ positivity, condition (EC vs. EO), laterality (left, midline, or right), and polarity (frontal, central, or posterior) for EEG alpha band power. Then, the EC-to-EO alpha reactivity index (ARI) was examined as a neurophysiological marker for predicting Aβ+ in depressed older adults. Results: The mean power spectral density of the alpha band in EO phase showed a significant difference between the Aβ+ and Aβ- groups (F = 6.258, p = 0.015). A significant 3-way interaction was observed among Aβ positivity, condition, and laterality on alpha-band power after adjusting for age, sex, educational years, global cognitive function, medication use, and white matter hyperintensities on MRI (F = 3.720, p = 0.030). However, post-hoc analyses showed no significant difference in ARI according to Aβ status in any regions of interest. Conclusion: Among older adults with depression, increased power in EO phase alpha band was associated with Aβ positivity. However, EC-to-EO ARI was not confirmed as a predictor for Aβ+ in depressed older individuals. Future studies with larger samples are needed to confirm our results.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2010.10a
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• pp.187-192
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• 2010

In this paper, intrusion detection technique based on the sound field variation of audio frequency in the security space is proposed. The sound field formed by sound source can be detected with the microphone when the obstacle or intruder is positioned. The sound field variation due to the intruder is based on the interference of audio wave. With the help of numerical simulation of sound field formations, the increase or decrease of sound pressure level is analyzed not only the obstacle, but also the intruder. Even the microphone is positioned behind the source, sound pressure level can be increase or decrease due to the interference. Frequency response test is performed with Gaussian white noise signal to get the whole frequency response from 0 to half of sampling frequency. There are three security cases. Case 1 is the situation of empty space with and without intruder, case 2 is the situation of blocking obstacle with and without intruder, and case 3 is the situation of side blocking obstacle with and without intruder. At each case, the frequency response is obtained first at the security space without intruder, and second with intruder. From the experiment, intruder size of $50cm{\times}50cm$ can be successfully detected with the proposed technique. Moreover, the case 2 or case 3 bring about bigger sound field variation. It means that the proposed technique have the potential of more credible security sensing in real situation.

• Earthquakes and Structures
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• v.4 no.4
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• pp.397-428
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• 2013

This paper examines whether the "effective period" of bilinear isolation systems, as defined invariably in most current design codes, expresses in reality the period of vibration that appears in the horizontal axis of the design response spectrum. Starting with the free vibration response, the study proceeds with a comprehensive parametric analysis of the forced vibration response of a wide collection of bilinear isolation systems subjected to pulse and seismic excitations. The study employs Fourier and Wavelet analysis together with a powerful time domain identification method for linear systems known as the Prediction Error Method. When the response history of the bilinear system exhibits a coherent oscillatory trace with a narrow frequency band as in the case of free vibration or forced vibration response from most pulselike excitations, the paper shows that the "effective period" = $T_{eff}$ of the bilinear isolation system is a dependable estimate of its vibration period; nevertheless, the period associated with the second slope of the bilinear system = $T_2$ is an even better approximation regardless the value of the dimensionless strength,$Q/(K_2u_y)=1/{\alpha}-1$, of the system. As the frequency content of the excitation widens and the intensity of the acceleration response history fluctuates more randomly, the paper reveals that the computed vibration period of the systems exhibits appreciably scattering from the computed mean value. This suggests that for several earthquake excitations the mild nonlinearities of the bilinear isolation system dominate the response and the expectation of the design codes to identify a "linear" vibration period has a marginal engineering merit.

• Journal of Animal Environmental Science
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• v.10 no.2
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• pp.119-126
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• 2004

The protein in the extracts from the skins of pineapple and kiwi and the optimal conditions to hydrolyze blood, egg and gluten meals with them were investigated. Protein analysis by SDS-polyacylamide gel electrophoresis showed one protein band with 22 kd molecular weight in the pineapple skin extract, and Hve protein bands with 27 kd, 22.5 kd, 22 kd, 19 kd, and 14.4 kd molecular weight in the kiwi skin extract. The 22 kd protein in the pineapple skin extract is assumed to be bromelain, and the 27 kd protein in the kiwi skin extract is assumed to be actinidin, both are pretense. The optimal conditions for hydrolysis of blood, egg, and gluten meals we: 6-24 hours in time, $60^{\circ}C$ in temperature, and pH 4-pH 7.

• Proceedings of the KIEE Conference
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• 1990.11a
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• pp.85-87
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• 1990

Silicon nitride film was deposited on a silicon wafer using a laser CVD(LCVD) technique, which is based on direct photolysis of $SiH_4/NH_3$ gas mixture by ArF laser beam(${\lambda}=193\;nm$). The refractive index of deposited SiN film is 1.9 at the temperature of $300^{\circ}C$, pressure of 5 torr. The breakdown field strength of LCVD SiN film was 10MV/cm. In IR spectrum, the absorption peak of Si-H, N-H, and Si-N is detected and it is shown that hydrogen is included in SiN film. From analysis of absorption band. it is calculated that density of Si-H, N-H bond is higher than $5{\times}10^{22}cm^{-3}$. LCVD MIS capacitor and PECVD MIS capacitor have injection-type hysteresis but it is known that hysteresis loss of LCVD MIS capacitor is smaller than that of PECVD MIS capacitor. It means that Interface state density of LCVD capacitor is smaller than that of PECVD capacitor. In addition, the flatband voltage($V_{FB}$) of LCVD is smaller than that of PECVD capacitor. And it means that fixed charged density($Q_{FIX}$) of LCVD capacitor is smaller than that of PECVD MIS capacitor.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.29 no.5
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• pp.397-400
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• 2018

This paper presents a miniaturized 65 nm CMOS 30~46 GHz wideband amplifier. To minimize the chip area, coupled inductors are used in the matching networks. The measurement shows that the fabricated amplifier exhibits 9.3 dB of peak gain, 16 GHz of 3 dB bandwidth, and 42 % fractional bandwidth. The measured input and output return losses were more than 10 dB at 35.8~46.0 GHz and 28.6~37.8 GHz, respectively. The chip consumes 42 mW at 1.2 V. The measured group delay variation is 19.1 ps within the 3 dB bandwidth and the chip size excluding the pads is $0.09mm^2$.

• Asian-Australasian Journal of Animal Sciences
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• v.26 no.11
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• pp.1577-1582
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• 2013

The effects of dietary supplementation of selenium (Se), iodine (I), and a combination of both on the blood haematology, serum free thyroxine (FT4) and free triiodothyronine (FT3) hormones and glutathione peroxidase enzyme (GSH-Px) activity were examined on twenty four (7 to 8 months old, $22{\pm}1.17$ kg live weight) Kacang crossbred male goats. Animals were randomly assigned to four dietary treatments (6 animals in each group). Throughout 100 d of feeding trial, the animals of control group (CON) received a basal diet, while the other three groups were offered basal diet supplemented with 0.6 mg/kg diet DM Se (SS), or 0.6 mg/kg diet DM I (PI), or a combination of both Se and I, each at 0.6 mg/kg diet DM (SSPI). The haematological attributes which are haemoglobin (Hb), red blood cell (RBC), packed cell volume (PCV), mean cell volume (MCV), white blood cells (WBC), band neutrophils (B Neut), segmented neutrophils (S Neut), lymphocytes (Lymph), monocytes (Mono), eosinophils (Eosin) and basophils (Baso) were similar among the four treatment groups, while serum levels of Se and I increased significantly (p<0.05) in the supplemented groups. The combined dietary supplementation of Se and I (SSPI) significantly increased serum FT3 in the supplemented animals. Serum GSH-Px activity increased significantly in the animals of SS and SSPI groups. It is concluded that the dietary supplementation of inorganic Se and I at a level of 0.6 mg/kg DM increased serum Se and I concentration, FT3 hormone and GSH-Px activity of Kacang crossbred male goats.

• Transactions of the Korean Society for Noise and Vibration Engineering
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• v.21 no.3
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• pp.212-219
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• 2011

In this paper, intrusion detection technique based on the sound field variation of audio frequency in the security space is proposed. The sound field formed by sound source can be detected with the microphone when the obstacle or intruder is positioned. The sound field variation due to the intruder is mainly caused by the interference of audio wave. With the help of numerical simulation of sound field formations, the increase or decrease of sound pressure level is analyzed not only by the obstacle, but also by the intruder. Even the microphone is positioned behind the source, sound pressure level can be increased or decreased due to the interference of sound wave. Frequency response test is performed with Gaussian white noise signal to get the whole frequency response from 0 to half of sampling frequency. There are three security cases. Case 1 is the situation of empty space with and without intruder, case 2 is the situation of blocking obstacle with and without intruder, and case 3 is the situation of side blocking obstacle with and without intruder. At each case, the frequency response is obtained first at the security space without intruder, and second with intruder. From the experiment, intruder size of diameter of 50 cm pillar can be successfully detected with the proposed technique. Moreover, the case 2 and case 3 bring about bigger sound field variation. It means that the proposed technique have the potential of more credible security guarantee in real situation.

• Journal of Microbiology and Biotechnology
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• v.12 no.6
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• pp.972-978
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• 2002

Streptomyces sp. AD001 is a Gram-positive soil actinomycetes secreting an uncharacterized 2,4-dichlorophenol (DCP) oxidizing enzyme, whose activity is similar to the previously known Actinomycetes lignin-peroxidase (ALiP). This extracellular peroxidase was purified from Streptomyces sp. AD001 as a single protein band on an SDS-PACE by ammonium sulfate fractionation, Q-sepharose, concanavalin A, and Bio-Gel HTP column chromatographies. The molecular mass of the purified peroxidase was determined by SDS-PAGE to be 45.2 kDa, and 49.7 kDa with MALDI-TOF-MS, respectively. The highest level of peroxidase activity was observed at pH 7.5 and $30^{\circ}C$. The amino terminal sequence of the purified peroxidase (G-E-P-E-E-G-N-V-D-G-T-L) showed no significant homologies to my known proteins, suggesting that Streptomyces sp. AD001 may secrete a novel kind of bacterial peroxidase Initial rate kinetic data of the 2,4-DCP oxidation were best modeled with a random-binding bireactant system.

• Proceedings of the Korea Electromagnetic Engineering Society Conference
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• 2000.11a
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• pp.125-129
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• 2000

In this paper, We designed and fabricated C-band bandpass filter using dielectric resonators. From waveguide cutoff frequency which applied the region between adjacent dielectric resonators, the height of cavity is determined. The cavity's diameter is determined to the twice of dielectric resonator's diameter considering the conductor loss. The resonant frequency of the DR-cavity is calculated with travelling wave mode analysis. Conventionally, circular cylindrical dielectric resonator is analysed by Cohn's model which use the evanescent mode in the region between dielectric resonator wall and circular cavity wall, which is an approximated method. The external quality factor, Q$_{ex}$ has found with simulation result using Ansoft's Maxwell simulation tool. The designed filter using dielectric resonators with dielectric constant of 45 has the passband center at 5.065GHz. The bandpass filter using dielectric resonators have about 1dB insertion loss. 20MHz bandwidth and more than 30dB attenuation at f$_{0}$$\pm$15MHz.z.z.