• 임상간호연구
• /
• 제30권1호
• /
• pp.35-44
• /
• 2024

Purpose: The purpose of this study is to compare the predictive validity of pressure injury risk assessment, Braden, Braden Q and Braden QD for pediatric patients. Methods: Prospective observational study included patients under the age of 19 who were hospitalized to general wards, intensive care units of a children's hospital. Characteristics related to pressure injury were collected, and predicted validity was compared by calculating the areas under the curve (AUC) of the Braden, Braden Q, and Braden QD scales. Results: A total of 689 patients were included in the study. A total of 13 (1.9%) patients had pressure injuries, and the number of pressure injuries was 17. Factors related to the occurrence of pressure injuries were 9 (52.9%) immobility-related and 8 (47.1%) medical device-related. The AUC for each scale was .91 (95% CI .89~.94) for Braden, .92 (95% CI .90~.95) for Braden Q, and .94(95% CI .92~.96) for Braden QD. The optimal cut-off points were identified as 16 for Braden (sensitivity=88.8%, specificity=86.4%), 17 for Braden Q(sensitivity=63.6%, specificity=94.9%), and 12 for Braden QD (sensitivity=94.4%, specificity=88.7%). Conclusion: The Braden QD scale demonstrated the highest predictive validity for pressure injuries in pediatric patients and is expected to be valuable tool in preventing pediatrics pressure injuries.

• 지구물리와물리탐사
• /
• 제10권3호
• /
• pp.191-202
• /
• 2007

한반도 남부지역의 세부적인 지진파 감쇠특성 규명을 위해, 기존에는 적용이 불가능하였던 Q 토모그래피 역산을 위한 사전 수치검증 연구를 수행하였다. 특히 강지진동모사를 위해 일반적으로 사용되고 있는 추계학적 점지진원 지진동 모델(stochastic point-source ground-motion model; Boore, 2003)에서 사용되는 Q 값에 대한 2차원(2D; 2 Dimensional) 토모그래피 역산을 시도함으로써 역산 결과가 강지진동모사에 직접 활용될 수 있도록 하였다. 수치검증 방법으로는 Q 토모그래피 checkerboard 시험방법이 사용되었는데, 이를 위해 광역 단일 Q 모델의 추계학적 지진동모델 파라미터 역산결과의 지진원과 부지효과 모델 파라미터 값을 이용해서 관측자료와 지진규모-거리-주파수-오차 분포가 동일한 스펙트럼 합성자료를 생성하였다. 수치검증을 위한 Q 블록 격자의 총 개수는 75개(내륙지역=69개(약 $35{\times}44km^2$의 격자크기); 해양지역=6개)로 설정하였으며, $Q_0f^{\eta}$ 함수형태의 Q 블록 값은 $Q_0$=100, 500, ${\eta}=0.0{\sim}1.0$의 분포를 갖도록 하고, 파선의 깊이는 별도로 고려하지 않았다. 스펙트럼 합성자료 생성에 이용된 모델파라미터의 정해와 모델파라미터의 역산결과를 비교하기 위한 checkerboard 수치검증은 3단계에 걸쳐 수행되었는데, 1단계는 블록별 Q의 초기값 추정 단계이며, 2단계는 관측소별 부지증폭함수를 추정하는 단계, 마지막 3단계에서는 최종적인 Q를 도출하는 단계이다. 관측소별 부지증폭함수의 초기 추정값으로는 기 분류된 관측소 등급에 대한 평균 부지증폭함수(연관희, 서정희, 2007)가 사용되었으며, 3단계의 checkerboard 수치검증 결과 최종적으로 추정된 부지효과 모델에는 오차가 발생하였으나 블록별 Q의 정해는 만족할 정도로 추정할 수 있었다.

• Journal of Ecology and Environment
• /
• 제35권3호
• /
• pp.203-212
• /
• 2012

The physiological effects of elevated $CO_2$ concentration and temperature were examined for Quercus gilva and Q. glauca grown under control (ambient $CO_2$ and temperature) and treatment (elevated $CO_2$ and temperature) conditions for 39 months. The objective of the study was to measure the long-term responses, in physiological parameters, of two oaks species exposed to elevated $CO_2$ and temperature. The photosynthetic rate of Q. gilva was found to be decreased, but that of Q. glauca was not significantly affected, after long-term exposure to elevated $CO_2$ and temperature. Stomatal conductance of Q. glauca was reduced by 21.7%, but that of Q. gilva was not significantly affected, by long-term exposure to $CO_2$ and temperature. However, the transpiration rate of the two oak species decreased. Water use efficiency of Q. gilva was not significantly affected by elevated $CO_2$ and temperature, while that of Q. glauca was increased by 56.6%. The leaves of Q. gilva grown under treatment conditions had an increased C:N ratio due to their reduced nitrogen content, while those of Q. glauca were not significantly affected by long-term exposure to elevated $CO_2$ and temperature. These results suggest that the long-term responses to elevated $CO_2$ and temperature between Q. gilva and Q. glauca are different, and that Q. gilva, the endangered species, is more sensitive to elevated $CO_2$ and temperature than Q. glauca.

• 대한전자공학회논문지SD
• /
• 제48권2호
• /
• pp.35-43
• /
• 2011

본 논문에서는 Quadrature LC VCO(Voltage controlled oscillator)의 I/Q 오차를 분석하고, 그 분석된 결과를 이용하여 I/Q 오차 보정 회로를 제안한다. 제안된 I/Q 오차 보정 회로는 높은 주파수 대역폭을 요구하는 위상 오차 검출기를 사용하는 대신에 낮은 주파수 대역폭으로도 동작이 가능한 진폭 오차 검출기를 사용한다. 제안된 I/Q 오차 보정 회로의 검증을 위하여 2.5GHz Quadrature LC VCO가 $0.18{\mu}m$ CMOS 공정으로 제작 및 측정되었다. 측정결과 제안된 진폭 오차 검출기를 사용해도 기존의 위상 오차 검출기는 사용하는 경우들과 유사한 I/Q 오차 보정 성능을 얻을 수 있음을 확인하였다. 본 I/Q 오차 보정 회로는 1.8V 전원 전압에서 0.4mA 전류를 소모하며, 차지하는 칩 면적은 $0.04mm^2$이다.

• 한국간호교육학회지
• /
• 제10권2호
• /
• pp.297-307
• /
• 2004

This study aims to identify the types and type-specific characteristics of subjectivity on complementary alternative therapy of nursing students using Q-methodology and to provide them as basic materials for nursing education. Q-methodology provides a scientific method for identifying perception structures that exist within certain individuals or groups. Thirty C college nursing students' classified 35 selected Q-statements into 9 points standard, according to the level of agreement or disagreement by forced normal distribution. The collected data was analyzed by using a QUNAL PC program. Resultingly, the attitude of nursing students regarding complementary alternative therapy was divided into three types. Type 1 is positive recognition. The students who think the therapy contributes to maintaining and improving health, and is a way to protect human body and improve welfare by enhancing immunity. Type 2 is objective acceptance. The students who think the complementary alternative therapy is effective when it is properly used for specific constitutions in discussion with medical teams after its effects are scientifically reviewed. Type 3 is popularity consideration. The students who put focus on its popular use and regard the therapy as very useful for not only patients but also ordinary healthy people because it is based on the natural and human approach. In conclusion, proposed are studies on influence factor of nursing students' awareness about the complementary alternative therapy and reviews on the effects of the complementary alternative therapy that is applied as nursing intervention.

• Journal of Plant Biotechnology
• /
• 제39권3호
• /
• pp.169-174
• /
• 2012

Quantitative trait loci (QTLs), which were related to the ability of callus induction and plant regeneration in seed culture of rice, were analyzed using a mapping population from a cross between the rice cultivars 'Samgang' (tongil type) and 'Nagdong' (japonica). A tongil type rice cultivar, 'Samgang' showed lower frequency (20%) of plant regeneration than that (35%) of japonica rice, 'Nagdong'. Transgressive segregations were observed for the ability of callus induction and plant regeneration from the seed-derived calli of 58 doubled haploid (DH) lines. The ability of plant regeneration of 58 doubled haploid lines showed a continuous distribution with comparatively wide range (10.0 to 66.7%) of variation. Composite interval mapping analysis was used to identify the QTLs controlling callus induction and plant regeneration ability. Four significant QTLs, qCWS6, qCWS8, qCWS9 and qCWS11, associated with callus weight per seed were detected on chromosomes 6, 8, 9, and 11 with LOD values of 3.30, 2.60, 2.70 and 2.43, explaining 36% of the total phenotypic variation. Three significant QTLs, qPR1, qPR6, and qPR11, for the ability of plant regeneration were located on chromosome 1, 6, and 11 at LOD score of 2.25, 2.15 and 2.55, accounting for 24 % of the total phenotypic variation. The present study should be useful for improving the efficiency of plant regeneration in tissue culture of indica rice by means of marker-assisted selection.

• 전기학회논문지
• /
• 제60권2호
• /
• pp.362-369
• /
• 2011

In this paper, optimal deep reactive ion etching (DRIE) process conditions for fused quartz were experimentally determined by Taguchi method, and fused quartz-based micro cantilevers were fabricated. In addition, comparative study on Q-factors of fused quartz and silicon micro cantilevers was performed. Using a silicon layer as an etch mask for fused quartz DRIE process, different 9 flow rate conditions of $C_4F_8$, $O_2$ and He gases were tested and the optimum combination of these factors was estimated. Micro cantilevers based on fused quartz were fabricated from this optimal DRIE condition. Through conventional silicon DRIE process, single-crystalline silicon micro cantilevers whose dimensions were similar to those of quartz cantilevers were also fabricated. Mechanical Q-factors were calculated to compare intrinsic damping properties of those two materials. Resonant frequencies and Q-factors were measured for the cantilevers having fixed widths and thicknesses and different lengths. The Q-factors were in a range of 64,000 - 108,000 for fused quartz cantilevers and 31,000 - 35,000 for silicon cantilevers. The experimental results supported that fused quartz had a good intrinsic damping property compared to that of single crystalline silicon.

• 한국가금학회지
• /
• 제43권1호
• /
• pp.47-54
• /
• 2016

Coenzyme Q10(CoQ10)은 자연계에 널리 분포하는 화합물로 세포호흡과 항산화제로서 그 기능이 잘 알려졌지만, 최근 유전자들의 발현 조절자로서의 가능성도 제시되었다. 따라서 본 연구는 산란계에서 CoQ10의 첨가 급이가 콜레스테롤과 지방산 대사관련 유전자들의 발현에 미치는 영향을 관찰하고자 실시하였다. Lohmann Brown(40주령) 36수를 CoQ10의 첨가원에 따라 대조군(CON, basal diet(BD)), CoQ10 건조분말 급여군(T1, BD+CoQ10 100 mg/kg 사료) 및 CoQ10 건조분말 유화처리군(T2, BD+micellar of CoQ10 100 mg/kg 사료) 등 모두 3처리구로 설정하여 5주간 사양시험을 실시하였다. 시험 종료 후 각 개체의 간으로부터 total RNA를 추출하고, real-time PCR을 이용하여 유전자들의 발현을 분석하였다. 콜레스테롤 합성 과정에서 주요 조절 효소인 HMGCoA reductase(HMGCR)의 유전자 발현은 대조구에 비하여 CoQ10 분말첨가인 T1과 유화처리된 T2 처리구에서 모두 약 50%씩 억제되었다(p<0.05). 내생 콜레스테롤의 합성을 촉진시키는 전사인자인 SREBP2 mRNA 발현 또한 대조구와 비교해서 T1과 T2에서 각각 30%와 40% 감소하였다(p<0.05). CoQ10의 첨가 급이는 대조구에 비하여 liver X receptor(LXR) 유전자가 약 30~35% 그 발현이 억제되었으며, sterol regulatory element-binding proteins(SREBPs)1 또한 T2에서 약 40% 유전자 발현이 감소하였다(P<0.05). 전사인자인 $PPAR{\gamma}$와 XBP1은 CoQ10에 의하여 약 15~40% 수준으로 효과적으로 억제됨을 확인하였다(p<0.05). 세포 내부로의 에너지 공급원인 포도당의 흡수를 담당하는 GLUT2는 약 35~60% 그리고 GLUT8은 약 25~30%의 유전자발현 각각 감소함을 보였다(p<0.05). CoQ10의 섭취는 중성지방 합성을 위한 지방합성효소(FASN)의 유전자 발현을 분말처리군에서 약 30%, 유화처리군에서 약 65% 억제됨을 확인하였다(P<0.05). 본 연구결과는 CoQ10 첨가급여가 콜레스테롤 및 지방대사 관련 유전자 발현에 영향을 미치며, 세포내 콜레스테롤과 지방의 생성도 억제할 수 있음을 보여주었다.

• Clinical and Experimental Reproductive Medicine
• /
• 제49권4호
• /
• pp.277-284
• /
• 2022

Objective: Oxidative stress is a key player in the development of idiopathic male infertility (IMI), and various antioxidants have been used for the treatment of IMI with inconsistent results. Coenzyme Q10 (CoQ10) is a cofactor and an antioxidant that may improve semen parameters and reduce oxidative stress in patients with idiopathic oligoasthenospermia (OA). Therefore, this study aimed to explore the effect of CoQ10 on semen parameters and antioxidant markers in patients with idiopathic OA. Methods: Fifty patients with idiopathic OA and 35 fertile controls were enrolled in this prospective controlled study. All participants underwent a comprehensive fertility assessment. All patients received CoQ10 (300 mg/day) orally once daily for 3 months. Semen parameters, seminal CoQ10 levels, reactive oxygen species (ROS) levels, total antioxidant capacity (TAC), superoxide dismutase (SOD), and glutathione peroxidase (GPx) were measured in patients and controls at the start of the study and after 3 months. Results: Treatment with CoQ10 resulted in increased sperm progressive motility (p<0.05), total motility (p<0.01), seminal TAC (p<0.01), SOD (p<0.05), GPx (p<0.001), and seminal CoQ10 (p<0.001) levels and reduced ROS (p<0.01) in patients as compared to baseline. Sperm concentration and motility were also significantly correlated with antioxidant measures and seminal CoQ10 levels (r=0.38-0.57). Conclusion: CoQ10 therapy (300 mg/day for 3 months) improved sperm motility and seminal antioxidant markers in patients with idiopathic OA. Therefore, CoQ10 could be a promising treatment for patients with idiopathic infertility and may improve their fertility potential.

• 청정기술
• /
• 제23권2호
• /
• pp.205-212
• /
• 2017

본 연구에서는 합성폐수로부터 암모니아 탈기 시 이유체 벤츄리형 선회 노즐이 장착된 제트 루프 반응기의 성능을 평가하고자 하였다. 이를 위해 이유체 벤츄리형 선회 노즐과 일반 노즐이 장착된 각각의 제트 루프 반응기를 이용하여 조업조건 변화에 따른 암모니아 제거효율과 총괄물질전달계수($K_La$)를 각각 얻은 후, 이를 통해 성능을 비교하였다. 운전변수로는 pH(pH = 10-12), 액체순환유량($Q_L=25-35L\;min^{-1}$), 공기유입량($Q_G=5-20L\;min^{-1}$)을 변화시키며 실험하였다. 실험결과, 동일한 조업조건에서 이유체 벤츄리형 선회 노즐(two-fluid venturi-type swirl nozzle, TVSN)이 장착된 제트 루프 반응기가 이유체 벤츄리형 일반 노즐(two-fluid venturi-type conventional nozzle, TVCN)이 장착된 제트 루프 반응기보다 암모니아 제거효율과 $K_La$가 높게 나타났다. 이와 같은 결과는 이유체 벤츄리형 선회 노즐이 장착된 제트 루프 반응기에서 형성된 선회류 흐름에 의해 난류강도가 이유체 벤츄리형 일반 노즐이 장착된 제트 루프 반응기에 비해 높기 때문이라 판단된다. 또한, 실험조건 범위에서 $K_La$는 pH, 공기유입량 및 액체순환유량이 증가할수록 증가하는 경향을 보였으며, 특히, 실험변수 중 공기유입량이 pH나 액체순환유량에 비해 $K_La$에 미치는 영향이 큰 것으로 나타났다.