• Radiation Oncology Journal
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• v.20 no.1
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• pp.24-33
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• 2002

Purpose : In order to improve dose homogeneity and to reduce acute toxicity in tangential whole breast radiotherapy, we evaluated two treatment techniques using multiple static fields or universal compensators. Materials and Methods : 1) Multistatic field technique : Using a three dimensional radiation treatment planning system, Adac Pinnacle 4.0, we accomplished a conventional wedged tangential plan. Examining the isodose distributions, a third field which blocked overdose regions was designed and an opposing field was created by using an automatic function of RTPS. Weighting of the beams was tuned until an ideal dose distribution was obtained. Another pair of beams were added when the dose homogeneity was not satisfactory. 2) Universal compensator technique : The breast shapes and sizes were obtained from the CT images of 20 patients who received whole breast radiation therapy at our institution. The data obtained were averaged and a pair of universal physical compensators were designed for the averaged data. DII (Dose Inhomogeneity Index : percentage volume of PTV outside $95\~105\%$ of the prescribed dose) $D_{max}$ (the maximum point dose in the PTV) and isodose distributions for each technique were compared. Results : The multistatic field technique was found to be superior to the conventional technique, reducing the mean value of DII by $14.6\%$ (p value<0.000) and the $D_{max}$ by $4.7\%$ (p value<0.000). The universal compensator was not significantly superior to the conventional technique since it decreased $D_{max}$ by $0.3\%$ (p value=0.867) and reduced DII by $3.7\%$ (p value=0.260). However, it decreased the value of DII by maximum $18\%$ when patients' breast shapes fitted in with the compensator geometry. Conclusion : The multistatic field technique is effective for improving dose homogeneity for whole breast radiation therapy and is applicable to all patients, whereas the use of universal compensators is effective only in patients whose breast shapes fit inwith the universal compensator geometry, and thus has limited applicability.

• Journal of Chest Surgery
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• v.42 no.3
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• pp.311-316
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• 2009

Background: Clopidogrel is widely used just before coronary artery bypass surgery, yet its pharmacological effect can cause postoperative bleeding-related complications. The purpose of this study was to find the effect of preoperative clopidogrel exposure on the blood transfusion requirement and on the rate of reexploration for bleeding control and the rate of readmission caused by bleeding in patients who undergo off-pump coronary artery bypass surgery (OPCAB). Material and Method: This study included 103 patients who had been on clopidogrel preoperatively and they underwent OPCAB by one surgeon from January, 2005 to November, 2007. We divided the patient into two group. Group 1 consisted of 45 patients who stopped cloidogrel 5 days before surgery and group 2 consisted of 58 patients who were taking clopidogrel within 5 days before surgery. Two groups were compared in terms of the bleeding related reoperation rate and the readmission rate, the amount of postoperative bleeding and the required amount of transfusion. Result: There were no significant differences between the two groups concerning the demographic, echocardiographic and hematologic features. There were no significant differences in the postoperative bleeding amount, but the amount of required transfusion was greater in group 2 (p=0.018). While group 1 showed a 0% reoperation rate for hemostasis and 0% readmission rate as related to postoperative bleeding, group 2 showed a 6.9% reoperation and a 5.2% readmission rate, but three were no statistically significant differences between the two groups. Conclusion: Continuous use of clopidogrel did not cause postoperative major bleeding, but can increase the amount of bleeding and the amount of required transfusion postoperatively. We that discontinuation of clopidogrel for a while before elective OPCAB can help the patient's postoperative recovery.

• Journal of the Korean Institute of Landscape Architecture
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• v.42 no.1
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• pp.64-74
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• 2014

Ecological parks enable the sustainable use of natural resources and can be used as a place for site based environmental education. This study presented an opportunity to expand the scope of user perceptions and leisure benefits into urban ecological parks. However, in-depth studies which are aimed at eco-park visitors seeking the leisure benefits of the eco experience programs are lacking. The primary purpose of this study was to examine the urban ecological park user' characteristics which were derived by analyzing the leisure benefits and attitudes for the environment. Also, the attitudes about the environment, and the leisure benefits of visiting urban ecological parks was found to influence visitors' overall satisfaction. To accomplish the purposes of this study, a questionnaire survey with 282 samples was carried out on the urban ecological park(Gildong ecological park, Yeouido tributary ecology park). The results of the analyses are as following: urban ecological park visitors had a positive attitude about the environment, and felt satisfied by the visitors' leisure benefits. The study also examined the relationships between visitors' expectations of the leisure benefits both before visiting and after visiting. The results showed that ecological park visitors had greater expectations regarding the leisure benefits of the ecological program. Leisure benefits have a positive influence on overall satisfaction, and a positive attitude for the environment does not affect satisfaction. This study reaches the conclusion that the ecology experience program utilizing ecological parks is very effective with regard to overall satisfaction in urban areas toward the general environment and ecological parks. One of the major implications of this study is to offer a way to improve user leisure benefits and promote ecological programs by developing ecological parks for the future.

• Journal of Korean Orthopaedic Sports Medicine
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• v.8 no.1
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• pp.26-32
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• 2009

Purpose: This study was performed to compare the strength of ligamentous attached sites of cadaveric distal femur and to obtain reliable biomechanical data to use in ligamentous reconstruction or augmentation. Materials and Methods: Fifteen cadaveric distal femurs were used for this study. After measuring the bone density, 5.0 mm cannulated screw (Experiment 1) or reconstructed porcine ligament (Experiment 2) was inserted into the each ligamentous attached sites of anterior cruciate ligament (ACL), posterior cruciate ligament (PCL), medial collateral ligament (MCL) and lateral collateral ligament (LCL). In experiment 2, reconstructed porcine graft was fixed with bioabsorbable screw in ligamentous insertion sites. And we measured the maximal pullout force of each ligamentous attached sites of cadaveric distal femur. Results: Average bone mineral density was $1.205{\pm}0.137\;g/cm^2$ in experiment 1, $1.236{\pm}0.089\;g/cm^2$ in experiment 2, which showed no statistically significant differences. In experiment 1, average pull-out strength of ACL, PCL, MCL and LCL group were $519.1{\pm}111.7$ N, $638.9{\pm}144.4$ N, $169.7{\pm}56.0$ N, $225.6{\pm}61.5$ N respectively. In experiment 2, the average pull-out strength were $310.6{\pm}31.0$ N, $379.9{\pm}47.4$ N, $104.0{\pm}14.4$ N, $131.5{\pm}21.9$ N respectively. In experiment 1, there was no significant difference between ACL and PCL group and between MCL and LCL group. However, the maximal pullout strength of MCL and LCL group were significantly lower than that of ACL and PCL group (p<0.01). Experiment 2 showed the same results of experiment 1. Conclusion: Because stiffness of MCL and LCL attached sites are much lower than that of ACL and PCL attached sites, we may consider augmented fixation in ligamentous reconstructions of MCL and LCL.

• Clinical and Experimental Pediatrics
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• v.49 no.6
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• pp.623-629
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• 2006

Purpose : The mortality rate of neonatal sepsis has been decreased, however, the incidence has not significantly decreased because of increased invasive procedures. This study was designed to make guidelines for choosing antibiotics by analyzing the causative microorganisms and their antibiotics sensitivity test according to the onset of neonatal sepsis. Methods : One hundred seven cases of culture proven sepsis in 89 patients admitted to the NICU of Chonnam University Hospital from Jan. 2000 to Dec. 2004, were enrolled. By reviewing the medical records, clinical data, laboratory findings, causative organisms and their antibiotics sensitivity, and mortality were analyzed. Results : The incidence of neonatal sepsis was 1.7 percent and more prevalent in premature and low birth weight infants. 85.4 percent of neonatal sepsis was late onset. Almost all microorganisms(92.9 percent) were gram-positive in early onset, however, two thirds were gram-positive and one third were gram-negative and Candida in late onset. Gram-negative organisms and Candida were more prevalent in patients who had central line. Gram-positive organisms were sensitive to vancomycin, teicoplanin, and gram-negative were sensitive to imipenem, and cefotaxime. Conclusion : Neonatal sepsis was more prevalent in premature and low birth weight infants. More than 90 percent were gram-positive in early onset, however, one third was gram-negative and Candida in late onset. The first choice of antibiotics were a combination of third generation cephalosporin and clindamycin in early onset, and third generation cephalosporin and glycopeptide in late onset. If there is no response to antibiotics treatment, the use of antifungal agents should be considered.

• Journal of the Korean Society for Marine Environment & Energy
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• v.11 no.4
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• pp.181-190
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• 2008

To response climate change and Kyoto protocol and to reduce greenhouse gas emissions, marine geological storage of $CO_2$ is regarded as one of the most promising option. Marine geological storage of $CO_2$ is to capture $CO_2$ from major point sources(eg. power plant), to transport to the storage sites and to store $CO_2$ into the marine geological structure such as deep sea saline aquifer. To design a reliable $CO_2$ marine geological storage system, it is necessary to perform numerical process simulation using thermodynamic equation of state. The purpose of this paper is to compare and analyse the relevant equations of state including ideal, BWRS, PR, PRBM and SRK equation of state. To evaluate the predictive accuracy of the equation of the state, we compared numerical calculation results with reference experimental data. Ideal and SRK equation of state did not predict the density behavior above $29.85^{\circ}C$, 60 bar. Especially, they showed maximum 100% error in supercritical state. BWRS equation of state did not predict the density behavior between $60{\sim}80\;bar$ and near critical temperature. On the other hand, PR and PRBM equation of state showed good predictive capability in supercritical state. Since the thermodynamic conditions of $CO_2$ reservoir sites correspond to supercritical state(above $31.1^{\circ}C$ and 73.9 bar), we conclude that it is recommended to use PR and PRBM equation of state in designing of $CO_2$ marine geological storage process.

• The Journal of Korean Society for Radiation Therapy
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• v.24 no.2
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• pp.149-155
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• 2012

Purpose: Long Extension (LE) is used in proton therapy for lung and abdomen. However, it has limitations in surface area, produces collision in posterior oblique beam which creates limitations in various gantry angles in planning therapy and increases air gap (distance between patient and compensator). Therefore, this study investigates the usability of manufactured Rounded Extension (RE) in comparison to LE to use the most suitable extension in proton therapy. Materials and Methods: To compare structural features of LE and RE. This study investigated usable gantry angle for snout sizes 100, 180 and 250 and CT scanned Humanoid phantom. And it compared the air gap in posterior oblique direction. Results: The structural features of two extensions are as follow. Because of the existence of supporting bar, the width of LE was 40 cm and RE was 50 cm. Result of the investigation of usable gantry angle for snout sizes 100, 180 and 250 are as follow. LE is ${\pm}36$ (average) at 180 degree and RE is ${\pm}70$ (average). And also, the air gap of RE is decreased by 11.3 cm in average at the same gantry angle. Conclusion: Manufactured RE for proton therapy has several benefits than LE. Its therapy surface area is wider and range of usable gantry angle is also wider. Also, the air gap at the posterior oblique beam has decreased. Therefore the usability of RE in proton therapy of lung and abdomen will be increased compared to LE. However, the air gap of proton therapy at the lateral direction may be increased, so there may be need for make up to decrease air gap at the lateral direction in the future.

• Journal of dental hygiene science
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• v.9 no.1
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• pp.145-151
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• 2009

The purpose of this study was to examine the correlation of oral health behavior, oral health state and PHP in an effort to facilitate the promotion of oral health and improve oral health care. The subjects in this study were patients who got a scaling at the oral hygiene practice lab in the department of dental hygiene in S college dental clinic from September 5 to December 1, 2007. The collected data were analyzed with SPSS WIN 12.0 program. The findings of the study were as follows: 1. The younger patients had a smaller number of FT index, and the older patients excelled the younger ones in oral health behavior involving the use of oral hygiene supplies, regular visit to dental clinics and dietary control. 2. The patients got 2.62 out of possible five points on oral health behavior, which indicated that their oral health behavior wasn't good enough. Those whose oral health behavior was better had a smaller number of DT index and a larger number of FT index. A better oral health behavior led to a lower PHP index. 3. There was a negative(-) interrelationship between oral health behavior and DT index, and oral health behavior had a positive(+) correlation with FT index. The oral health behavior had a negative(-) correlation to PHP index, which showed that a better oral health behavior led to a lower PHP index. The above-mentioned findings seem to suggest that oral health behavior is one of integral factors to affect oral health status and PHP index, and the kind of oral health education that could change oral health care attitude should be provided during scaling practice after grasping the actual oral health behavior of patients.

• Journal of the Korean Society of Food Science and Nutrition
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• v.37 no.5
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• pp.589-597
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• 2008

The purpose of this study is to arrange for the systematic execution of safety control in children's foods through nutrition and hygiene standard suggestions and guidelines for quality certification system in children's preferable food. Aiming to achieve this objective, the study researched the present status of children’s preferable food sold near elementary schools, elicited the hazards and problems of those foods and selected nutritional and hygienic hazard components in those foods. To suggest the standards and guidelines for quality certification in children's preferable food, the study referred to sundry records, surveyed the practical cases of relevant policies and standards at home and abroad. We studied the standard of nutrition for the quality certification in those foods for sugar, fat, sodium, and additives (tar color: red No. 2 in a ban on use, caffeine), microorganism (aflatoxin $B_1$ (${\mu}g$/kg) and pathogenic bacteria (Staphylococcus aureus, Bacillus cereus, Salmonella spp.), which are the nutrients that may hamper health when taken in a large amount, and the standard for a diet restricted to under 200 kcal per one serving size. Results of distribution of processed foods (242 samples) by nutrition standards were as follows. In case of all ‘low’ level in total sugar, total fat and sodium, 0.4% of total samples was possible to be certified, In case of all ‘medium’ level in total sugar, total fat and sodium, maximumly 22.3% of total samples was possible to be certified. In case of all medium level in nutrients and $\leq$200 kcal/serving, 17.8% of total samples was possible to be certified. Certified food types was milk products and beverages.

• Clinical and Experimental Pediatrics
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• v.51 no.9
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• pp.956-963
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• 2008

Purpose : Indomethacin is widely used for the prophylaxis and treatment of patent ductus arteriosus (PDA); however, it is associated with side effects such as renal failure, intraventricular hemorrhage, and gastrointestinal bleeding. Intravenous ibuprofen has been shown to be as effective as indomethacin in prompting PDA closure. If treatment with oral ibuprofen is as effective as indomethacin, it would have the advantages of greater availability, simpler administration, and lower cost. We conducted this study to compare the efficacy and side effects of indomethacin with those of oral ibuprofen, vis-$\grave{a}$-vis on the pharmacological closure of PDA. Methods : As a randomized double-blind study, 34 preterm infants with respiratory distress syndrome and hemodynamically significant PDA were treated with either intravenous indomethacin or oral ibuprofen. Echocardiography was performed by one cardiologist who was blind to the treatment that any given infant received. The rate of ductal closure, the need for additional drug treatment or surgical ligation, clinical outcome, and the side effects of drug treatment were compared. Results : Ductal closure occurred in 16 of 18 patients (88.9%) from the indomethacin group and in 14 of 16 patients (87.5%) from the ibuprofen group (P>0.05). Three patients in the indomethacin group and four in the ibuprofen group required a second drug treatment (P>0.05). Three patients (i.e., one patient in the indomethacin group and two in the ibuprofen group) underwent surgical ligation (P>0.05). Between the two groups, there was no significant difference vis-$\grave{a}$-vis in side effects or clinical outcome. Conclusion : Compared to indomethacin, oral ibuprofen has the advantages of simpler administration and lower cost, while being as effective; in addition, there are no differences between the two drug treatments with regards to side effects or clinical outcomes. Therefore, the widespread use of oral ibuprofen should be considered in treating PDA in preterm infants.