• Journal of the Optical Society of Korea
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• 제17권4호
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• pp.289-295
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• 2013

Although low-level laser therapy (LLLT) has been a valuable therapeutic technology in the clinic, its efficacy may be reduced in deep tissue layers due to strong light scattering which limits the photon density. In order to enhance the photon density in deep tissue layers, this study developed an optical tissue clearing (OTC) laser probe (OTCLP) system which can utilize four different OTC methods: 1) tissue temperature control from 40 to $10^{\circ}C$; 2) laser pulse frequency from 5 to 30 Hz; 3) glycerol injection at a local region; and 4) a combination of the aforementioned three methods. The efficacy of the OTC methods was evaluated and compared by investigating laser beam profiles in ex-vivo porcine skin samples. Results demonstrated that total (peak) intensity at full width at half maximum of laser beam profile when compared to control data was increased: 1) 1.21(1.39)-fold at $10^{\circ}C$; 2) 1.22 (1.49)-fold at a laser pulse frequency of 5 Hz; 3) 1.64 (2.41)-fold with 95% glycerol injection; 4) 1.86 (3.4)-fold with the combination method. In conclusion, the OTCLP system successfully improved the laser photon density in deep tissue layers and may be utilized as a useful tool in LLLT by increasing laser photon density.

• Childhood Kidney Diseases
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• 제9권2호
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• pp.149-158
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• 2005

목 적 : 소아 신증후군 환아 중 신생검을 시행한 경우 그 임상적, 검사적 특징과 조직학적 소견, 그리고 치료 길과를 보기 위해 연구를 시행하였다. 방 법 : 1984년부터 2004년까지 21년 동안 경희의료원 소아과에서 신생검을 시행 받은 169명(남아 130명, 여아 39명)에 대해 그 임상적 특징, 검사 소견, 병리 소견들과 치료 결과를 후향적으로 조사하였다. 신생검의 적응증으로는 입원 당시 비특이적 소견을 보이거나 빈발재발형, 스테로이드 의존성, 스테로이드 저항성 등의 소견으로 세포 독성 약제 치료가 필요했던 경우였다. 결 과 : 약 반수의 환아(52.1$\%$)에서만 미세변화형을 보였고, 그 다음으로는 미만성 메산지움증식형 33.1$\%$, 초점 분절사구체신염 5.3$\%$, 막증식사구체신염 2.4$\%$, 막성신병증 2.4$\%$, Ig A 신염 1.8$\%$ 등이었다. 미세변화형의 경우보다 미세변화형이 아닌 진단명인 경우 혈뇨와 스테로이드에 저항성을 보일 확률이 높았다. 총 37명의 스테로이드 저항성 환아 중 장기간에 걸쳐 스테로이드 치료를 시행한 결과 30명(81.0$\%$)에서 마침내 완해를 보였다. 결 론 : 신생검이 필요했었던 환아의 약 절반에서 미세변화형이 아닌 결과를 보였다. 비정형적 특징들 중 혈뇨와 스테로이드 저항성이 미세변화형이 아닌 진단과 가장 연관되었다. 스테로이드 저항성 환아에서도 장기간의 메틸스테로이드 충격요법으로 좋은 완해율을 보였다.

• 대한물리치료과학회지
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• 제3권2호
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• pp.989-995
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• 1996

본 연구는 건물 계단을 올라감에 따른 심폐기능의 변화를 알아보기 위해 안동전문대학 물리치료과에 재학 중인 1, 2, 3학년 학생 총 136명 중 50명을 무작위로 추출하여 1995년 9월 20일에서 10월 3일까지 14일간 조사된 연구의 분석결과는 다음과 같다. 1. 연구대상자의 일반적인 특성 중 신장은 평균 166.4cm, 체중은 57.7kg이었다. 2. 안정시 수축기혈압은 평균 121.3mmHg, 이완기 혈압은 78.5 mmHg였다. 3. 안정시 맥박수는 평균 71.8회, 호흡수는 20.4회, 체온은 $36.8^{\circ}C$였다. 각 층에서 심폐기능의 변화를 파악하기 위해 분산분석을 실시한 결과는 다음과 같다. 1. 측정 후 2, 3, 4충간의 수축기혈압은 각각 129.0 mmHg, 127.0 mmHg, 132.0 mmHg로 3층에서는 약간 낮았으나 점차 증가하였고 (P=0.1919), 이완기혈압도 80.1mmHg, 76.5mmHg, 82.0 mmHg로 3층에서 약간 낮은 후 점차 증가하였으나 통계적 차이는 없었다(P=0.4229). 2. 맥박수는 2, 3, 4층에서 각각 74.0회, 73.1 회, 74.0회로 충간의 뚜렷한 차이가 없었다(P = 0.8148). 3. 호흡수는 2, 3, 4층에서 21.4회, 23.1회, 24.6회로 층수가 높아짐에 따라 횟수가 증가하여 통계적으로 유의한 차이를 보였다(P = 0.0071). 4. 체온은 2, 3, 4층에서 36.8, 36.6, $36.5^{\circ}C$로 통계적으로 유의하게 낮아짐을 나타내었다(P=0.0040). 따라서 본 연구결과에 의하면 건물의 계단을 올라감에 따라 호흡수는 증가하였고, 체온은 낮아짐을 알 수 있었다. 그래서 중추신경계환자 및 노약자들은 이 점을 의식해야 될 것으로 사료되며, 본 연구는 정상인을 대상으로 측정을 실시하였지만 향후 환자를 대상으로 한 연구가 요구된다.

• 대한한의학회지
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• 제26권3호
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• pp.80-97
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• 2005

Backgrounds : In recent years there has teen renewed interest in the importance of 8-constitution medicine as evidenced by growth of research in this field. Although diagnosis by 8-constitution depends on pulse types, it still is subjective and thus could be insignificant. Therefore, diagnosis based on objective characteristics is essential. Objectives : The purpose of this study was to find objective characteristics of the 4-constitution groups {木(Mok; hepatonia, cholecystonia), {土(To; pancreotonia, gastrotonia), {金(Gum; pulmotonia, colonotonia), {水(Soo; renotonia, vesicotonia)} in 8-constitution for further diagnosis and therapy. Also, some significant clinical tendencies of 4-constitution groups were studied. Methods : From Nov. 2001 to Apr. 2004, data were collected through a questionnaire given to 720 patients who were classified into one of 8 constitutions according to their pulse types and their responses to constitution-based acupuncture therapy. The questionnaire was composed of 80 items which were about personality, physical shape, habit, physiological and pathological symptoms, response to drugs, favorites and responses to various foods. The data were statistically analyzed by cross-tabulation and one-way analysis of variance, and SPSS V10.0.7PC was used. Results : The results are summarized as follows: 1) Among participants, proportions of hepatotonia, pancreotonia, and cholecystotonia were higher than those of vesicotonia, pulmotonia, colonotonia, renotonia, grstrotonia. 2) 52 items of 80 variances showed significant differences by gender, 3) 13 items were highly correlated with 4-constitution groups in males, and 26 items in fremales. 4) 22 items showed significant group differences among 4-constitution groups in males, and 41 items in females. Also, for each item 4-constitution groups were sorted according to their means, so that the constitutional tendencies were objectively figured out by personality, shape, habit, physiological and pathological symptoms, response to drugs, favorites and responses to foods. Conclusions : Most clinical characteristics of 4-constitution groups found in this study coincided with those from the previous ones in this fold. Thus, classifying patients into one of the 4-constitution groups based on significant objective characteristics is of great benefit to diagnosis and therapy. further study should be followed to improve proper therapy for each constitution.

• 한국융합학회논문지
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• 제8권1호
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• pp.97-106
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• 2017

본 융합연구의 목적은 척추마취하에서 전립선절제수술을 받는 환자의 불안, 피로 및 활력징후에 미치는 선호 음악요법의 효과를 확인하기 위함이다. 본 연구는 비동등성 대조군 전후시차설계에 따라 환자 45명을 대상으로 하였으며 실험군에게는 수술 중 선호하는 음악을 들려주었다. 자료는 수술 30분전, 수술 20분 경과, 수술 40분 경과, 및 마취회복실 입실직후에 구조화된 질문지와 직접 계측을 통해 수집하였으며 기술통계, ${\chi}^2-test$, Fisher's exact test, t-test 및 repeated measures ANOVA로 분석하였다. 연구결과 실험군의 불안과 피로수준은 대조군보다 유의하게 낮았다(p=.001; p=.020). 그러나 수축기혈압, 이완기혈압 및 맥박에서는 두 집단 간 유의한 차이가 없었다(p=.821; p=.473; p=.782). 이상의 연구결과를 통해 척추마취 전립선절제술을 시행하는 환자에게 수술 중 환자의 선호 음악요법을 제공하는 것은 수술 관련 불안과 피로를 완화하는 유용한 간호중재가 될 수 있음을 확인하였다.

• 근관절건강학회지
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• 제1권1호
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• pp.48-70
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• 1994

The purpose of this study was to determine the effects of music therapy on acute, subacute and chronic pain and depression of musculoskeletal trauma patients. The study was designed using nonequivalent control group pretest-posttest design within the framework of an adaptation model. The subjects were composed of forty patients, and twenty of them were assigned to the experimental group and twenty to the control group within the unit of patients. Data were summarized as follows : 1. There were significant changes of pain scores in an experimental and a control group measured before and after the treatment. 2. There were significant changes of pulse rates, respiration rates and systolic blood pressure, but were no significant changes of diastolic blood pressure in an experimental and a control group measured before and after the treatment. 3. There were no significant changes of the amount of ${\beta}$-endorphin in an experimental and a control group measured before and after the treatment. 4. There were no significant changes of depression scores in an experimental and a control group measured before and after the treatment. As a result, music therapy was a useful nursing intervention for relief of acute, subacute and chronic pain. Two suggestions could be made on the ground of the results of this study. 1. On the basis of endogenous pain control theory, it's necessary to research the changes of the amount of ${\beta}$-endorphin as the effect of the music therapy on patients having severe pain. 2. It's necessary to research the changes of the amount of ${\beta}$-endorphin according to the lapse of time after the music therapy for pain relief.

• 한국산학기술학회논문지
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• 제16권2호
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• pp.1189-1199
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• 2015

본 연구의 목적은 산부인과 전신마취 수술환자의 불안과 활력징후에 선호음악이 미치는 효과를 검증하는 것이다. 연구 설계는 비동등성 대조군 전후 시차설계이다. 연구기간은 2013년 5월 1일부터 7월 30일까지이며, 대상자는 W대학병원의 산부인과 수술환자로 실험군 21명, 대조군 23명, 총 44명이다. SPSS Win 18.0을 활용하여 Repeated measures ANOVA로 자료를 분석하였다. 연구 결과 선호음악을 제공받은 실험군과 제공받지 않은 대조군 간의 불안은 수술실 입실 시와 마취직전 사이 및 마취 직전과 의식 회복 후(p=.003; p=.011)의 시점에서 유의한 차이를 보였다. 수축기 혈압은 의식 회복 후와 회복실 퇴실 시 사이에 유의한 차이를 보였으며(p=.023), 맥박은 마취 직전과 의식 회복 후 사이에서 유의한 차이가 있었다(p=.016). 향후 선호음악 요법은 산부인과 전신마취 수술환자의 불안 감소 및 안정된 활력징후를 유지를 위한 효과적인 간호중재로 적용될 수 있다.

• 한국전문물리치료학회지
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• 제20권1호
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• pp.18-27
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• 2013

The purpose of this study was to compare the ring lock type knee-ankle-foot orthosis (KAFO) with newly developed 4-bar linkage KAFO on the gait characteristics of persons with poliomyelitis clinically. This 4-bar linkage is the stance control type KAFO which provide the stability during stance phase and knee flexion during swing phase. Two subjects participated in this study voluntarily. We provided the customized 4-bar linkage KAFO then asked the subjects to walk in level surface and stairs under the two different KAFO conditions. The characteristics of gait in the persons with poliomyelitis were evaluated using a 3D motion analysis system and force plate. Additionally 6 minute walk test for physiological cost index were conducted using pulse oximeter to measure the energy consumption. In the results of this study, the differences of 4-bar linkage KAFO compared with ring lock type KAFO are as follows: (1) Walking speed, stride length, and step length on level increased in subjects, (2) The gait symmetry was improved by generated knee flexion and decreased pelvic external rotation on level and stairs walking, (3) Decreased vertical excursion of center of mass and pelvic elevation during swing phase was decreased on level, (4) Knee extension moment, hip flexion moment, hip and knee internal rotation moment of non-braced limb were decreased on level walking, (5) Walking speed in 6-minute walk test was increased and physiological cost index was decreased. These findings indicate that 4-bar linkage KAFO compared with ring lock type KAFO is effective in enhancing pattern, endurance, and energy consumption in level surface and stairs walking.

• 한방재활의학과학회지
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• 제25권4호
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• pp.123-137
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• 2015

Objectives The aim of this clinical study was to find out the changes of vital sign, body composition, skin status before and after combined spa-exercise therapy in participants of middle-aged women. Methods In this study 24 participants of middle-aged women went through 12 weeks of combined spa-exercise therapy. Each week vital sign, body composition, skin status were measured before exercise, which consisted of warming-up, whole body exercise and final exercises bathing in spa ($32{\sim}36^{\circ}C$). Results 1. The average of systolic blood pressure significantly decreased from $126.38{\pm}19.33mmHg$ to $120.46{\pm}11.18mmHg$ after 11 weeks of spa-exercise therapy (p<0.05). 2. The average of moisture of skin significantly increased from $36.83{\pm}3.18$ to $44.21{\pm}7.43$ after 11 weeks of spa-exercise therapy (p<0.05). 3. The average of elasticity of skin significantly increased from $59.75{\pm}3.50$ to $62.63{\pm}2.29$ after 11 weeks of spa-exercise therapy (p<0.05). 4. The average of diastolic blood pressure, pulse, et cetera. didn't significantly change after spa-exercise therapy. Conclusions The results showed that 12 weeks of spa-exercise therapy had significant effect on reducing systolic blood pressure, increasing moisture, elasticity of skin in participants of middle-aged women, which means spa-exercise therapy may be used as a treatment on high blood pressure and cutaneous diseases. Further studies are anticipated to find out other various effects of spa-exercise therapy.

• Journal of Periodontal and Implant Science
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• 제27권3호
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• pp.469-478
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• 1997

The purpose of this study was to evaluate the structural change of root surface and the occlusion of dentinal tubule following $CO_2$ laser treatment. Seven extracted healthy human premolar werw curetted, sectioned, and four specimens were randomly assigned to each of 6 different treatment groups : 1) untreated EDTA etched control: 2) root plande only: 3) $CO_2$ laser treated with 2W mode 6(10msec/pulse, 20pps) for 1 minute: 4) $CO_2$ laser treated with 2W mode 6(lOmsec/pulse, 20pps) for 2 minutes: 5) $CO_2$ laser treated with 2W mode 7(20msec/pulse, 20pps) for 1 minute: 6) $CO_2$ laser treated with 2W mode 7(20msec/pulse, 20pps) for 2 minutes. Following the prescribed treatment, the specimens were prepared for SEM evaluation. Results showed that $CO_2$ laser may be effective to occlude dentinal tubules tor dentin sensitivity treatment. The effect of dentinal tubule occlusion was enhanced with increasing the total energy level lased to specimen regardless of lasing mode. The structural changes of root surfaces were restricted to superficies, and these changes included fissuring, charring, crater formation over the smooth lava like texture. The charring and crater formation implying root damage was observed in the case of the longer duration of a pulse. The results of the present study suggests that the pulsed $CO_2$ laser with shorter pulse duration and longer exposure time can be used effectively in order to obtain the optimal dentinal tubule occlusion with minimal root damage.