• 동의생리병리학회지
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• 제20권1호
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• pp.245-256
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• 2006

This research sought to survey oriental medicine diagnosis methods currently practiced, analyze their advantages and disadvantages, and work out clinical establish direction for oriental medicine diagnosis methods. Oriental medicine diagnosis methods currently practiced in the related circles are categorized into traditional Korean diagnosis methods and holistic auxiliary diagnosis methods. The traditional Korean diagnosis method focuses on treating diseases of traditional Korean health management methods which are based on the bodily self-viability capabilities according to the Orient's viewpoint of health. Under the diagnosis method, based on the cognition of maximizing the state of the bodily self-viability capabilities together with the characteristics of diseases, symptoms, pulse, first face-to-face patient observation, physical constitution, and life principle are managed according to form, color, pulse and symptom which divide the bodily viability capacities into inherent and acquired elements amid both elements interacting.

• 대한임상검사과학회지
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• 제53권3호
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• pp.241-248
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• 2021

본 연구는 고혈압이 있는 대한민국 성인에서 아스파르트산 아미노전이효소(aspartate aminotransferase, AST)/알라닌 아미노전이효소(alanine aminotransferase, ALT) 비율과 맥압(pulse pressure, PP) 사이의 관계를 평가하기 위해 수행되었다. 제6차 국민건강영양조사(KNHANES VI-3, 2015)에서 성인 1,515명의 데이터를 분석했다. 본 연구에서는 몇 가지 중요한 결과가 있다. 첫째, AST (odds ratio [OR], 1.018; 95% confidence interval [CI], 1.002~1.033), ALT (OR, 0.982; 95% CI, 0.969~0.996) 및 AST/ALT ratio (OR, 1.367; 95% CI, 1.027~1.819)는 고PP 결정하는 독립적인 요인이었다. 둘째, 관련변수(연령, 성별, 흡연, 음주, 규칙적인 운동, TC, TG, HDL-C, FBG, BMI, WC)를 조정한 후의 결과에서 AST/ALT ratio의 1 사분위에 대한 고PP의 OR을 기준으로, AST/ALT ratio의 2 사분위(OR, 1.188; 95% CI, 0.817~1.727) 및 AST/ALT ratio의 3 사분위(OR, 1.169; 95% CI, 0.800~1.710)는 유의하지 않았지만, AST/ALT ratio의 4 사분위(OR, 1.632, 95% CI, 1.113~2.393)에서 유의하게 높았다. 결론적으로, 고혈압이 있는 대한민국 성인에서 고PP은 AST/ALT ratio 및 AST와 양의 상관관계가 있었지만 ALT와 음의 상관계가 있었다.

• 한국지반공학회:학술대회논문집
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• 한국지반공학회 2001년도 봄 학술발표회 논문집
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• pp.167-174
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• 2001

Reflection method using ultrasonic source has been attempted to obtain the information about tunnel lining structures composed of lining, shotcrete, water barrier and voids at the back of lining. In this work, two different types of sources, i.e. single-pulse source and sweep source, can be used. Single-pulse source with short time duration has the frequency content whose amplitudes tend to be concentrated around the dominant frequency, whereas sweep source with long time duration denotes a flat distribution of relatively larger amplitude over a broad frequency band, although the peak to peak amplitude of single-pulse source wavelet is equivalent to that of sweep source one. In traditional seismic application, a single-pulse source(weight drop, dynamite) is typically used. However, to investigate the fine structure, as it is the case in the tunnel lining structure, the sweep wavelet can be also a desirable source waveform primarily due to the higher energy over a broad frequency band. For the investigation purposes of sweep source, a physical modeling is a useful tool, especially to study problems of wave propagation in the fine layered media. The main purpose of this work was using a physical modeling technique to explore the applicability of sweep source to the delineation of inner layer boundaries. To this end, a two-dimensional physical model analogous to the lining structure was built and a special ultrasonic sweep source was devised. The measurements were carried out in the sweep frequency range 10 ∼ 60 KHz, as peformed in the regular reflection survey(e.g. roll-along technique). The measured data were further rearranged with a proper software (cross-correlation). The resulting seismograms(raw data) showed quitely similar features to those from a single-pulse source, in which high frequency content of reflection events could be considerably emphasized, as expected. The data were further processed by using a regular data processing system "FOCUS" and the results(stack section) were well associated with the known model structure. In this context, it is worthy to note that in view of measuring condition the sweep source would be applied to benefit the penetration of high frequency energy into the media and to enhance the resolution of reflection events.

• 한국한의학연구원논문집
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• 제18권1호
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• pp.59-74
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• 2012

Objective : The aim of this study is to investigate current status of Sasang constitutional medicine researches and to provide source in setting a development strategy and making a policy on the Sasang constitutional medicine. Method : This study analyzed trends in research as represented in the 142 articles of Korea Institute of Oriental Medicine in the field of Sasang constitution medicine from 2007 to 2010. Result : The main themes of studies were Sasang constitution clinical study (68, 47%) and developing instruments for measuring diagnosis (48, 33%), especially pulse diagnosis (25, 17%). Genetic researches and trends studies on Sasang constitutional medicine were respectively 17 (12%) and 8 (5%). As a result, Korea Institute of Oriental Medicine established Sasang clinical information bank, and discovered clinical character of Sasang constitution to develope various diagnosis tools include constitution survey form and pulse diagnosis instrument. Genetic researches also discover constitution related genes such as FTO and MC4R, and explore association between heredity and Sasang constitution. Conclusion : The above mentioned achievements of Korea Institute of Oriental Medicine were limited to diagnosis process, unquestionably studies for reproducibility and authenticity of constitution diagnosis were important mission of Sasang constitutional medicine. However, to develop the advance of Sasang constitutional medicine, not only constitution diagnosis but also constitutional treatment studies should be conducted.

• Journal of Electrical Engineering and Technology
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• 제10권3호
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• pp.916-924
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• 2015

Electromagnetic Interference (EMI) is a system to system or environment to system phenomenon. The literature survey proved that the Randomized Pulse Width Modulation (RPWM) technique is a promising technique to reduce EMI. A new Constant Trailing Edge, Randomized Pulse Width Modulation (CTERPWM) technique is proposed in this paper. The effect of the proposed RPWM technique for mitigation of conducted-EMI on Cuk converter operating in Continuous Conduction Mode (CCM) is simulated and tested. In this paper, the analytical expressions for the Power Spectral Density (PSD) are derived for the proposed RPWM technique and are validated by experimental measurements. The effectiveness of the proposed RPWM technique on the mitigation of conducted-EMI is verified comparing simulation and experimental results and it is identified that both the results are almost similar with allowable experimental deviations. The comparative investigation proves that the proposed RPWM technique can mitigate and spread the dominant peaks of conducted-EMI over the complete spectrum for the Cuk converter. Based on the investigation the CTERPWM technique is recommended for adoption.

• 동아시아식생활학회지
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• 제8권3호
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• pp.280-288
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• 1998

The purpose of this study was to evaluate the nutrient and food intake status in underweight female college students living in Seoul. 126 underweight(BMI<20) and 74 normal weight (20$\leq$BMI<25) students were asked for their daily food intake and eating habits by using 3-day food records and questionnaire. We analyzed the amounts of the nutrient intakes and food groups as the subjects. The mean of height and weight were 162.1cm and 49.0kg in underweight and 160.6cm and 54.9kg in normal weight subjects. The mean energy, iron, and vitamin A intakes among the students were smaller than RDA for Koreans. The mean calcium(p<0.01), sodium(p<0.05), and vitamin B$_2$(p<0.05) intakes in underweight subjects were significantly higher than those in normal weight subjects. Total food intakes of underweight and normal weight students were 1235.8g and 1078.1g, respectively. The mean of the pulse group in the underweight was significantly higher than that in normal group(p<0.01) Frequently consumed food or dish items of the subjects were Kimchi, cooked rice, and milk. In the relation between BMI and dietary factors, the BMI was found to have a significant negative correlation with calcium intake(p<0.05), pulse intake(p<0.01) and eating habit score(p<0.01) Eating habit scores about quantity of food and lipid intake showed a significant difference between underweight and normal students.

• Journal of Microbiology and Biotechnology
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• 제16권10호
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• pp.1650-1655
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• 2006

Bacteria belonging to the genus Paenibacillus are facultatively anaerobic endospore formers and are attracting growing ecological and agricultural interest, yet their genome information is very limited. The present study surveyed the genomic features of P. polymyxa ATCC $842^T$ using pulse-field gel electrophoresis of restriction fragments and sample genome sequencing of 1,747 reads (approximately 17.5% coverage of the genome). Putative functions were assigned to more than 60% of the sequences. Functional classification of the sequences showed a similar pattern to that of B. subtilis. Sequence analysis suggests nitrogen fixation and antibiotic production by P. polymyxa ATCC $842^T$, which may explain its plant growth-promoting effects.

• 한국자기공명학회논문지
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• 제17권2호
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• pp.98-104
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• 2013

The ERETIC (Electronic REference To access In vivo Concentrations)2 method is a new qNMR experimental technique to measure analytes based on the signal of the reference compound without additional hardware equipment. In this study, ERETIC2 method was validated, and we sought to identify whether it would be possible to apply this method to a specific compound analysis of metabolites in plant. The $90^{\circ}$ pulse value (P1) and spin-lattice relaxation time ($T_1$) of each compound were measured for ERETIC2. The $9^1H$ of 3-(trimethylsilyl) propionic-2,2,3,3-$d_4$ acid (TSP) was used as a reference peak for ERETIC 2, and then, a suitable solvent and pulse sequence for each compound were selected. Under the NOESY-presat sequence, the relative accuracy error for quantitative analyses of primary metabolites was within the range of 5%, with the exception of glucose, which showed ${\geq}$ 55% error due to saturation. It showed excellent results for the quantification of glucose by using a $30^{\circ}$ pulse sequence, which did not suppress the water peak. In addition, the quantitative accuracy for secondary metabolites was extremely accurate, with an error ${\leq}$5% when considering the purity of the standard sample. The ERETIC2 method showed outstanding linearity, precision, and accuracy.

• 한국콘텐츠학회논문지
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• 제17권6호
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• pp.396-407
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• 2017

본 연구는 일개 대학 치위생과에 스켈링을 받으러 내원한 환자를 대상으로 스켈링 전과 후의 불안 및 공포와 vital sign 변화를 알아보기 위해 2015년 8월부터 11월까지 실시되었다. 자기기입식 설문지 작성과 Vital Sign을 측정하여 진행하였으며, 다음과 같은 결론을 얻었다. 불안 및 공포에 대한 항목 중 '마취용 주사바늘을 볼 때 두려움을 느낀다.'가 가장 높은 점수를 보였으며, 스케일링 전과 후에 각각 2.84점, 2.51점으로 조사되었다. 스케일링 전 맥박은 분당 77.48회에서 스케일링 후 분당 74.36회, 혈압은 스케일링 전 수축기 혈압이 124.86mmHg에서 122.34mmHg로 유의하게 감소하였다. 스케일링 전과 후의 불안 및 공포와 Vital Sign 변수들 간의 상관관계는 모두 수축기 혈압과 이완기 혈압이 가장 높은 양의 상관관계를 보였으며, 일반적 특성에 따른 불안의 경우 스케일링 전에 여자는 2.40점, 남자는 1.86점, 스케일링 후에는 여자 2.16점, 남자 1.65점으로 각각 조사되었다. 일반적 특성에 따른 Vital Sign의 경우 스케일링 전 수축기혈압이 남자가 133.59mmHg, 여자가 118.31mmHg으로 조사되었으며, 스케일링 후에는 수축기혈압이 남자가 129.36mmHg, 여자가 117.87mmHg으로 나타나 통계적으로 유의한 차이를 보였다. 연령에 따른 Vital Sign은 스케일링 후의 이완기 혈압의 경우 10대 69.63mmHg, 20대 76.48mmHg, 30대 이상은 79.29mmHg으로 연령이 증가할수록 이완기 혈압이 상승하는 것으로 조사되었다. 이상의 결과를 정리해보면 스케일링 전과 후의 불안 및 공포와 Vital Sign은 변화가 있으며, 성별, 거주지, 연령 직업 등이 불안과 Vital Sign 변화에 영향을 미치는 것으로 나타났다. 이에 본 연구를 바탕으로 치과에 방문하는 환자들의 불안과 공포를 줄일 수 있는 방안에 대한 연구가 필요할 것으로 사료된다.

• 한국산학기술학회논문지
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• 제14권6호
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• pp.2735-2742
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• 2013

본 연구는 국가자료인 2010년도 국민건강영양조사 자료를 이용하여 20세 이상 성인에서 비타민 D와 맥압의 관련성을 평가하고자 실시하였다. 연구결과에서 PP에 양의 상관관계를 보이는 변수는 연령(p<0.01), TG(p<0.01), TC(p<0.01), FBS (p<0.01), BMI(p<0.01), 허리둘레(p<0.01) 등이었고, 음의 상관관계를 보이는 경우는 HDL-C(p<0.01), 신장(p<0.01), 체중(p<0.01), 25(OH)D(p<0.01) 등이었다. 연령, 신장, 체중, 허리둘레, BMI, TC, TG, HDL-C, FBS, 25(OH)D 등의 독립변수를 사용한 다중선형회귀분석결과에서, PP에 영향을 주는 독립변수는 연령(p<0.001)과 허리둘레(p<0.001), FBS (p<0.001), 25(OH)D(p<0.001), TC(p<0.001), 체중(p<0.001), HDL-C(p<0.001) 등이었다. 결론적으로, 비타민 D의 감소가 PP증가에 영향을 주는 요인이었으며, 비타민 D를 적정수준으로 유지 하는 것은 관상동맥질환의 발생률을 감소시킬 수 있을 것으로 기대된다.