• Title/Summary/Keyword: Pulse Analysis

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New Geochronological and Lead Isotopic Data for Porphyry-Skarn Cu-Mo-Au Deposits in the Andahuaylas-Yauri Batholith, Southeastern Part of Peru (페루 남동부 안다우아일라스-야우리 저반에 부존하는 반암-스카른 동-몰리브데늄-금광상의 새로운 지질연대 및 납동위원소 자료)

  • Acosta, Jorge;Heo, Chul-Ho;Villarreal, Eder;Yauli, Synthia;Salazar, Carlos;Yang, Seok-Jun;Ortega, Moises;Zorrilla, Braulio
    • Journal of the Mineralogical Society of Korea
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    • v.32 no.1
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    • pp.71-77
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    • 2019
  • New geochronological data of U-Pb, Re-Os and the lead isotope analysis of the Cu-Mo-Au mineral deposits are reported in the Trapiche and Constancia around Apurimac province, southeastern part of Peru. The measured ages were the first regional pulse of previously reported mineralization age between 28 and 33 Ma. The lead isotopic results indicate two sources of mineralization. The first source is thought to be derived from the upper crust and the second one is thought to be derived from a mixture of the upper crust and the lower crust.

3D Printing-Based Ultrafast Mixing and Injecting Systems for Time-Resolved Serial Femtosecond Crystallography (시간 분해 직렬 펨토초 결정학을 위한 3차원 프린팅 기반의 초고속 믹싱 및 인젝팅 시스템)

  • Ji, Inseo;Kang, Jeon-Woong;Kim, Taeyung;Kang, Min Seo;Kwon, Sun Beom;Hong, Jiwoo
    • Korean Chemical Engineering Research
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    • v.60 no.2
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    • pp.300-307
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    • 2022
  • Time-resolved serial femtosecond crystallography (TR-SFX) is a powerful technique for determining temporal variations in the structural properties of biomacromolecules on ultra-short time scales without causing structure damage by employing femtosecond X-ray laser pulses generated by an X-ray free electron laser (XFEL). The mixing rate of reactants and biomolecule samples, as well as the hit rate between crystal samples and x-ray pulses, are critical factors determining TR-SFX performance, such as accurate image acquisition and efficient sample consumption. We here develop two distinct sample delivery systems that enable ultra-fast mixing and on-demand droplet injecting via pneumatic application with a square pulse signal. The first strategy relies on inertial mixing, which is caused by the high-speed collision and subsequent coalescence of droplets ejected through a double nozzle, while the second relies on on-demand pneumatic jetting embedded with a 3D-printed micromixer. First, the colliding behaviors of the droplets ejected through the double nozzle, as well as the inertial mixing within the coalesced droplets, are investigated experimentally and numerically. The mixing performance of the pneumatic jetting system with an integrated micromixer is then evaluated by using similar approaches. The sample delivery system devised in this work is very valuable for three-dimensional biomolecular structure analysis, which is critical for elucidating the mechanisms by which certain proteins cause disease, as well as searching for antibody drugs and new drug candidates.

A Study on UX of Shared Electric Scooters Using Gamification: Focusing on User Engagement and Motivation (게이미피케이션을 이용한 공유 전동킥보드 서비스 UX 연구: 사용자 참여와 동기 부여 향상을 중심으로)

  • Lee, Ja-Eun;Kim, Dongwhan
    • The Journal of the Korea Contents Association
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    • v.22 no.2
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    • pp.173-186
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    • 2022
  • The purpose of this study is to investigate the influence of gamification strategies on improving participation and motivation of shared electric scooter users. To this end, this study derived the user type through the first research question of how the shared electric scooter usage behavior and pulse are, and derived user tasks and scenarios. The second research question, a shared electric kickboard app with gamification, was tested by users to see if it helps increase user participation and form motivation. As a result of the analysis, it was found that users were induced to be considerate of other users by using a combination of the motivational, relational, and self-expression strategies of gamification. Second, it was found that the use of motivation, achievement and reward, and reward visualization strategy elements promotes user's voluntary behavior. Third, through relationship, achievement, and reward strategies, users participated to create a positive culture of shared electric scooters, drawing immediate feedback, indicating that convenience has increased. In conclusion, it was found that the user helped to play a positive role in voluntary participation and motivation through the use of the shared electric kickboard service with gamification.

Experiment and Analysis of Backscattering Signals According to Presence or Absence of Chloroform (클로로폼 침적 유무에 따른 후방산란신호 측정 실험 및 분석)

  • Him Chan Seo;Jee Woong Choi;Yongmyung Kim;Moonjin Lee
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.28 no.spc
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    • pp.18-22
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    • 2022
  • Because it is difficult to apply direct and optical detection techniques to sunken hazardous and noxious substances (HNS), effective acoustic detection techniques are required to detect sunken HNS in water. In this study, the possibility of acoustic detection of sunken HNS was investigated through backscattering signal measurement experiments using chloroform, a sunken HNS. After establishing a pool in an acrylic tank, backscattering signals were measured according to the presences or absence of chloroform by varying the grazing angle from 90° to 50° in 0.5° intervals using a pan&tilt system. A directional transducer transmitted and received sinusoidal signals with a frequency of 200 kHz and a pulse length of 25 ㎲ in a monostatic state. When chloroform was deposited, the received level of the backscattering signal at the interface between water and chloroform became low at a grazing angle of approximately 80° or smaller. Based on the backscattering signal results obtained at the interface between water and chloroform, the possibility of acoustic detection of sunken HNS was demonstrated.

A Case of Hemophagocytic Lymphohistiocytosis with Clonal Karyotype Abnormalities (클론성 염색체이상을 보인 혈구포식 림프조직구증 1예)

  • Choi, Gae-Ryung;Kim, Ha-Nui;Cho, Chi-Hyun;Yoo, Byoung-Joon;Kim, Myung-Han;Kim, Jang-Su;Lim, Chae-Seung;Lee, Kap No
    • Laboratory Medicine Online
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    • v.1 no.2
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    • pp.110-114
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    • 2011
  • There have been a few reports of hemophagocytic lymphohistiocytosis (HLH) with chromosomal abnormalities. Clonal chromosomal abnormalities in HLH patients are usually found in association with hematologic malignancies and rarely with epstein-barr virus (EBV) infection. Here, we report a fatal case of HLH with clonal karyotype abnormalities. A 75-yr-old man was admitted with persistent anorexia and high fever. Laboratory data revealed pancytopenia, hypofibrinogenemia, hyperferritinemia, prolonged prothrombin time and activated partial thromboplastin time, and marked elevated level of serum transaminases. In real time-PCR using whole blood, EBV DNA was not detected but cytomegalovirus (CMV) DNA was detected. The bone marrow aspiration smear showed hyperplasia of mature histiocytes with prominent hemophagocytosis. In chromosomal analysis of bone marrow aspirates, complex chromosomal abnormalities were found. In spite of steroid pulse therapy and antibiotic treatment, he died of disseminated intravascular coagulopathy.

A Study for the Efficient Improvement Measures of Military EMP Protection Ability (국방 EMP 방호능력의 효율적 개선을 위한 방안 연구)

  • Jung, Seunghoon;An, Jae-Choon;Hwang, Yeung-Kyu;Jung, Hyun-Ju;Shin, Yongtae
    • Asia-pacific Journal of Multimedia Services Convergent with Art, Humanities, and Sociology
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    • v.7 no.1
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    • pp.219-227
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    • 2017
  • Current military command information system uses electronic equipment a lot on which semiconductor chip is attached. It seems its' importance will increase more with latest information communication technology developing. Electronic equipment which uses electricity contains regular tolerance to high output electric signal. And EMC specification is the standardized of this electronic equipment's tolerance. On the other hand, the Institute of Atomic Energy Research has ever declared that high output electromagnetic pulse(EMP) will be broken out within the radius of 170Km when 10kt nuclear explosion occurs at an altitude of 40Km above Seoul. Then, the region suffer from the damage of most electronic equipments. Therefore, the norm to protect the influences in that case is defined by EMP protection specification. Most common electronic equipments meet the EMC norm, but there is no way to check whether they meet the EMP norm or not. That is because it is difficult to check whether they meet EMP protection norm and is on the matter of cost. Except inevitable cases, there is no review of checking whether they meet the norm or not. Considering the above, in this research, we speculate about the measures to improve military EMP protection ability by analyzing the EMC-EMP correlation and checking the EMP protection ability of general electronic equipment through the analysis.

Differences in the cardiovascular change in normal and obese according to treadmill exercise (트레드밀 운동에 따른 정상인과 비만인의 심혈관계 변화 차이)

  • Kyung-jin Lee;Young-jun Kim;Sung-hwan Ji;Jeongwoo Jeon;Jiheon Hong;Jaeho Yu;Jinseop Kim;Seong-Gil Kim;Dongyeop Lee
    • Journal of Advanced Technology Convergence
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    • v.2 no.2
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    • pp.39-47
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    • 2023
  • The purpose of this study is to examine the difference in cardiovascular changes between obese people and the general public using a treadmill. This study was conducted by recruiting 32 adult males who had no experience in hospital visits or treatment due to cardiovascular disease. The subjects were divided into an obese group and a general group based on BMI 25 and performed treadmill exercise for 12 minutes. SBP, DBP, HR, MAP, and PP before and after the treadmill were measured to see the difference in cardiovascular system changes. Data analysis was evaluated using an independent t-test. In the case of SBP, MAP, and PP, there were significant differences between groups (P<0.05). For DBP and HR, no significant difference was found between the two groups (P>0.05). The subjects of this study consisted only of healthy adult males in their 20s, and there is a limitation in that it was performed in a short time.

Analysis of Clinical Indicators related to Pattern-Identification in Acute Cerebral Infarction Patient (급성기 뇌경색 환자에 있어 변증형별 유의한 임상지표의 분석)

  • Lee, Eun-chan;Hyun, Sang-ho;Kwak, Seung-hyuk;Woo, Su-kyung;Park, Ju-young;Jung, Woo-sang;Moon, Sang-kwan;Cho, Ki-ho;Park, Sung-wook;Ko, Chang-nam
    • The Journal of the Society of Stroke on Korean Medicine
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    • v.13 no.1
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    • pp.33-42
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    • 2012
  • Object : The aim of this study was to assess the clinical indicators related to Pattern-Identification(PI) in acute cerebral infarction patients. Methods : We studied hospitalized patients within 30days after ictus, who admitted at Korean Medicine Center of Kyung-Hee University from January 2010 to October 2012.(n=290) Two Traditional Korean Medicine(TKM) physicians evaluated the patients independently and diagnosed PI. Inter-rater reliability was measured using simple percentage agreement and the Cohen's kappa(κ) coefficient. To assess the clinical indicators closely related to each PI, we analysed average score of each indicator in each group. Results : Simple percentage agreement of PI between raters was 64.83% and Cohen's kappa(κ) coefficient was 0.526(95% CI: 0.451-0.600). Inter-rater reliability level was fair to good. We analysed the clinical indicators in each group. Significant indicators for Fire-Heat Pattern(FHP) were reddened complexion and strong pulse power, and meaningful indicators for FHP were halitosis and thick tongue fur. Significant indicator for Dampness-Phlegm Pattern(DPP) was overweight and there was no meaningful indicator. Significant indicator for Yin-Deficiency Pattern(YDP) was dry tongue fur and meaningful indicator for YDP was thirst. There was no significant indicator for Qi-Deficiency Pattern(QDP) and pale complexion and faint low voice were meaningful indicators for QDP. Conclusions : This study reveals the significant and meaningful clinical indicators related to each Pattern-Identification in acute cerebral infarction patients. It will contribute to standardization of Korean Medical Diagnosis and Treatment in acute cerebral infarction patients.

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Guided-mode Resonances in Periodic Surface Structures Induced on Si Thin Film by a Laser (레이저에 의해 생성된 Si 박막의 주기적 표면 구조에서의 도파모드 공진 연구)

  • Ji Hyuk Lee;Yoon Joo Lee;Hyun Hong;Eun Sol Cho;Ji Young Park;Ju Hyeon Kim;Min Jin Kang;Eui Sun Hwang;Byoung-Ho Cheong
    • Korean Journal of Optics and Photonics
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    • v.34 no.6
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    • pp.241-247
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    • 2023
  • We examine the spectral characteristics of laser-induced periodic surface structures (LIPSSs) formed on an amorphous silicon film irradiated by a 355-nm nanosecond laser. A Gaussian beam with a diameter of 196 ㎛ is used to perform a two-dimensional raster scan. The laser's pulse number is varied from 190 to 280, and its intensity is adjusted within 100-130 mJ/cm2. LIPSSs with a periodicity of approximately 330 nm form on the surface of the Si film, aligned perpendicular to the laser's polarization. Transmission spectra of the samples show dips around 700 nm for transverse electric polarization and around 500 nm for transverse magnetic polarization. The features are investigated with a one-dimensional-grating model using a rigorous coupled-wave analysis. Simulations confirm that the observed dips are due to the resonant modes, depending on the polarization.

Imaging Assessment of Visceral Pleural Surface Invasion by Lung Cancer: Comparison of CT and Contrast-Enhanced Radial T1-Weighted Gradient Echo 3-Tesla MRI

  • Yu Zhang;Woocheol Kwon;Ho Yun Lee;Sung Min Ko;Sang-Ha Kim;Won-Yeon Lee;Suk Joong Yong;Soon-Hee Jung;Chun Sung Byun;JunHyeok Lee;Honglei Yang;Junhee Han;Jeanne B. Ackman
    • Korean Journal of Radiology
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    • v.22 no.5
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    • pp.829-839
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    • 2021
  • Objective: To compare the diagnostic performance of contrast-enhanced radial T1-weighted gradient-echo 3-tesla (3T) magnetic resonance imaging (MRI) and computed tomography (CT) for the detection of visceral pleural surface invasion (VPSI). Visceral pleural invasion by non-small-cell lung cancer (NSCLC) can be classified into two types: PL1 (without VPSI), invasion of the elastic layer of the visceral pleura without reaching the visceral pleural surface, and PL2 (with VPSI), full invasion of the visceral pleura. Materials and Methods: Thirty-three patients with pathologically confirmed VPSI by NSCLC were retrospectively reviewed. Multidetector CT and contrast-enhanced 3T MRI with a free-breathing radial three-dimensional fat-suppressed volumetric interpolated breath-hold examination (VIBE) pulse sequence were compared in terms of the length of contact, angle of mass margin, and arch distance-to-maximum tumor diameter ratio. Supplemental evaluation of the tumor-pleura interface (smooth versus irregular) could only be performed with MRI (not discernible on CT). Results: At the tumor-pleura interface, radial VIBE MRI revealed a smooth margin in 20 of 21 patients without VPSI and an irregular margin in 10 of 12 patients with VPSI, yielding an accuracy, sensitivity, specificity, positive predictive value, negative predictive value, and F-score for VPSI detection of 91%, 83%, 95%, 91%, 91%, and 87%, respectively. The McNemar test and receiver operating characteristics curve analysis revealed no significant differences between the diagnostic accuracies of CT and MRI for evaluating the contact length, angle of mass margin, or arch distance-to-maximum tumor diameter ratio as predictors of VPSI. Conclusion: The diagnostic performance of contrast-enhanced radial T1-weighted gradient-echo 3T MRI and CT were equal in terms of the contact length, angle of mass margin, and arch distance-to-maximum tumor diameter ratio. The advantage of MRI is its clear depiction of the tumor-pleura interface margin, facilitating VPSI detection.