• 한국전산유체공학회:학술대회논문집
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• 2008.03b
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• pp.105-106
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• 2008

As a carrier of malaria and sneak of blood, mosquitoes are an unpleasant insect. However, there are several unknown natural secretes related with mosquitoes. Among them, we focused on the blood sucking process of a female mosquito. The main objective of this study is to understand the mosquito's blood sucking mechanism that can be used to resolve the problem encountered in the injection or transport of infinitesimal biological fluids in a micro-chip. At first, the velocity fields of blood-sucking flow in a proboscis were measured using a micro-particle image velocimetry (PIV) technique. The velocity signals of flow in the proboscis show periodic variation. This seems to be resulted from the beating of the pharyngeal pump which works as driving power. To analyze the pumping mechanism, the temporal variation of the pharyngeal pump was visualized using the synchrotron X-ray micro-imaging technique. The volume variation was estimated by the help of digital image processing techniques. Once the main mechanism of blood sucking process was found, a effective micro-pumping system with high efficiency would be developed in near future.

• Journal of Mechanical Science and Technology
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• v.19 no.spc1
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• pp.343-349
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• 2005

There are many things in common between hemodynamics in arterial systems and multibody dynamics in mechanical systems. Hemodynamics is concerned with the forces generated by the heart and the resulting motion of blood through the multi-branched vascular system. The conventional hemodynamics model has been intended to show the general behavior of the body arterial system with the frequency domain based linear model. The need for detailed models to analyze the local part like coronary arterial tree and cerebral arterial tree has been required recently. Non-linear analysis techniques are well-developed in multibody dynamics. In this paper, the studies of hemodynamics are summarized from the view of multibody dynamics. Computational algorithms of arterial tree analysis is derived, and proved by experiments on animals. The flow and pressure of each branch are calculated from the measured flow data at the ascending aorta. The simulated results of the carotid artery and the iliac artery show in good accordance with the measured results.

• Journal of Korean Neurosurgical Society
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• v.56 no.4
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• pp.348-352
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• 2014

High-flow vertebral arteriovenous fistulas (VAVF) are rare complications of cervical spine surgery and characterized by iatrogenic direct-communication of the extracranial vertebral artery (VA) to the surrounding venous plexuses. The authors describe two patients with VAVF presenting with ischemic presentation after C1 pedicle screw insertion for a treatment of C2 fracture and nontraumatic atlatoaxial subluxation. The first patient presented with drowsy consciousness with blurred vision. The diffusion MRI showed an acute infarction on bilateral cerebellum and occipital lobes. The second patient presented with pulsatile tinnitus, dysarthria and a subjective weakness and numbness of extremities. In both cases, digital subtraction angiography demonstrated high-flow direct VAVFs adjacent to C1 screws. The VAVF of the second case occurred near the left posterior inferior cerebellar artery originated from the persistent first intersegmental artery of the left VA. Both cases were successfully treated by complete occlusion of the fistulous portion and the involved segment of the left VA using endovascular coil embolization. The authors reviewed the VAVFs after the upper-cervical spine surgery including C1 screw insertion and the feasibility with the attention notes of its endovascular treatment.

• Journal of the Korean Society of Visualization
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• v.21 no.2
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• pp.14-23
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• 2023

The pressure difference across stenotic blood vessels is a commonly used clinical metric for diagnosing many cardiovascular diseases. At present, most clinical pressure measurements rely solely on invasive catheterization. In this study, we propose a novel method for non-invasive pressure estimation using the incompressible Navier-Stokes equations and a 3D multi-path integration approach. We verify spatio-temporal convergence on an in-silico dataset of a cylindrical straight pipe phantom with steady and pulsatile flow fields. We then evaluate the proposed method on an in vitro dataset of reconstructed control, pre-operative, and post-operative carotid artery cases acquired from 4D flow MRI. The performance of our method is compared to existing approaches based on the pressure Poisson equation and work-energy relative pressure. The results demonstrate the proposed method's high accuracy, robustness to spatio-temporal subsampling, and reduced sensitivity to noise, highlighting its great potential for non-invasive pressure estimation.

• Journal of Biomedical Engineering Research
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• v.22 no.6
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• pp.535-542
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• 2001

Endovascular embolization technique using a steno is currently used to treat the wide neck aneurysm. Since intraaneurysmal flow characteristics affect thrombus formation and embolisation process. flow visualization technique incorporating photochromic dye was used to elucidate hemodynamic changes by stenting Inside the fusiform aneurysm models. Qualitative observation of flow field and measurement of wall shear rates were Performed at five aneurysm wall locations under pulsatile flow. Intraaneurysmal flow motion was reduced and sluggish vortical motion was maintained during late deceleration phase by stenting. Also wall shear rates were reduced and OSI's were increased in the stented model. These flow characteristics Provide hemodynamic environment favorable for thrombus formation and intimal hyperplasia. The results of this study show hemodynamic changes by stenting Promote thrombus formation and aneurysm embolisation.

• Archives of Reconstructive Microsurgery
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• v.7 no.1
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• pp.15-19
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• 1998

Microsurgical free-tissue transfer has allowed surgeons to salvage injured limbs but choosing appropriate healthy recipient vessels has proved to be a difficult problem. Retrograde flow flaps are established in island flaps. Retrograde flow anastomosis could prevent the possible kinking and twisting of the arterial anastomosis. By not interrupting the proximal blood flow to the fracture or soft tissue defect site, the compromise of fracture or wound healing might be prevented. We wished to estabilish an animal model in rat for a retrograde arterial flow based free flap. Nembutal-anesthetized male rats; weighing 250 to 300 gm, were used. The femoral artery and common carotid artery were exposed and divided. The systemic and retrograde arterial pressure were quantified by utilizing a parallel tubing system connected with peripheral arterial line. In this study, the retrograde flow was not pulsatile and the retrograde arterial pressure was 64-65mmHg, with a mean arterial pressure of 106-109mmHg. An epigastiic skin flap, measuring $3{\times}3cm$, was raised with its vascular pedicle. The epigastric free flap was transfered in the same rat from femoral vessels to carotid vessels in end to end fashion. We anastomosed the donor arteries to the distal parts of the divided recipient arteries and the donor veins to the proximal parts of the recipient veins. Twelve experiments were performed and the transplantations succeeded in 75 percent of them. In the remaining 25 percent, the experiments failed due to thrombosis at the site of anastpmosis, or other causes. This animal model represents an excellent example of retrograde arterial flow free flap transfer that is reliable.

• Proceedings of the SAREK Conference
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• 2007.11a
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• pp.606-611
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• 2007

Pulsation is an inherent phenomenon in reciprocating compressors. It interacts with piping to cause vibrations and performance problems. Indiscriminately connecting to a compressor can be dangerous and cost money in the form of broken equipment and piping, poor performance, inaccurate metering, unwanted vibration, and sometimes noise. Piping connected to a compressor can materially affect the performance and response. To minimize these detrimental effects, reciprocating compressor system should be equipped by pulsation suppression system. This study discusses pressure pulsation phenomena occurred in a reciprocating compressor system. An experiment applied air compressor unit, as pulsating pressure generator, has been done. The compressor was connected sequentially to a snubber model and pressure tank. Sensor probes were placed on the inlet and outlet pipes of snubber. Compressor was driven by a motor controlled by a frequency regulator. The experiment was conducted by adjusting the regulator at 40Hz. General information about an internal gas flow can be achieved by numerical analysis approach. Information of the velocity, pressure and turbulence kinetic energy distribution are presented in this paper. Based on this result, the design improvement might be done.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.38 no.12
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• pp.971-974
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• 2014

A ventricular assist device (VAD) is used for bridge to heart transplantation and heart diseases. Knowing the status of a pneumatic pulsatile VAD when implanting it into the body is important: when the velocity of blood flow through the VAD is slow, a thrombus may occur, and thrombosis can be fatal to a patient. In order to determine the state of a VAD, various sensors need to be implanted. Because this introduces the risk of infection and difficulties with sensor management, we developed a method for estimating the state of a VAD indirectly via the pressure in an air tube that can be measured in vitro. We compared the measured values to in vitro experimental results. The estimated and measured values showed some errors, but the accuracy can be improved by refining the estimation process to minimize the risk of infection.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2005.06a
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• pp.1472-1477
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• 2005

Recently, the performance development of the exhaust system of a car is very important. The most important part of parts that constructing the exhaust system of a car is a muffler. The muffler reducing the exhaust noise from the engine influence on the engine performance directly. The inner parts of the muffler construct with the baffle and perforated pipes and so on. In the recent study, the study to design the semi-active muffler sensing the exhaust gas pressure controlling the back pressure variably with a EVV progress activity. So that the inner parts of the muffler show the complicated turbulent flow phenomena because of pulsatile flow from the engine and the structural properties and so on. The qualitative and quantitative analysis about the turbulent flow phenomena of the inner parts of the muffler is required gradually. In this study, to analysis the flow field of the inner parts of the muffler, analysis results with the PIV measurement to be able to analysis the variable change of the time and the space. Therefore, try to show the design variables to need to design the inner parts of a muffler of a car.

• Proceedings of the Acoustical Society of Korea Conference
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• autumn
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• pp.179-182
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• 2004

혈관의 협착으로 인만 혈류의 교란과 그로 인한 초음파 반향의 영향을 튜브에 편심 협착 (eccentric stenosis)을 부착하고 돼지 혈액을 이용해 실험실에서 연구했다. 상용화된 GE LOGIQ 700 Expert 시스템과 M12L 의 선형 트랜스듀서를 이용해 B-모드 영상을 얻은 후 편심 협착 상류 지점과 하류 지점의 초음파 영상을 비교하여 분석하였다. 분당 20 회와 40 회의 박동율과 혈류속도를 바꿔가며 혈류의 교란에 따른 혈액에서의 초음파 영상을 분석한 결과, 편심 협착으로 인한 혈류의 교란으로 적혈구 응집현상이 달라져 복잡한 초음파 반향 분포가 형성되었다. 비침습적 실시간 초음파 영상은 편심 협착으로 인한 혈류의 교란과 그로 인한 혈액의 적혈구 응집 현상을 이해하고 연구하는데 도움이 된다.