• Journal of Chest Surgery
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• 제22권1호
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• pp.163-169
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• 1989

Sclerosing hemangiomas of the lung are uncommon benign tumors. Although their histologic appearances are distinct and well-defined, their histogenesis is uncertain. Liebow and Hubbell reported seven cases of unusual pulmonary lesions which they named sclerosing hemangiomas in 1856. Similar cases had previously been reported under different names: Xanthoma, pulmonary histiocytoma, Xanthofibroma. We have experienced 3 cases of sclerosing hemangioma of lung at the Department of Thoracic and Cardiovascular Surgery, Yonsei University, college of Medicine, Seoul, Korea during a period of December 1985 through September 1988. This report is an early result of surgical treatment of three patients with pulmonary sclerosing hemangioma and their pathologic findings.

• Journal of Chest Surgery
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• 제25권10호
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• pp.1076-1081
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• 1992

The sclerosing hemangioma of the lung is rare, benign neoplasms, which are usually solitary, Althoughh their histologic apperances are distinct and well-defined, their histogenesis is uncertain. We experienced a typical lesion of pulmonary sclerosing hemangioma clinically and histologically, which was removed from the right lobe of 64-year-old female. We disccused histogenesis, microscopic feature and progress of the sclerosing hemangioma.

• Journal of Chest Surgery
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• 제20권3호
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• pp.574-577
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• 1987

So-called sclerosing hemangioma of the lung is a rare benign neoplasm of uncertain histiogenesis, with a complex but characteristic histologic appearance. We experienced a typical lesion of pulmonary sclerosing hemangioma clinically and histologically, which was removed from the right lower lobe of 22-year-old male and was reviewed by Darryl Carter at Yale University. We discussed histiogenesis, microscopic features and prognosis of the sclerosing hemangioma.

• Journal of Chest Surgery
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• 제44권1호
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• pp.39-43
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• 2011

Background: Pulmonary sclerosing hemangioma is a rare thoracic tumor, and pathophysiology or clinical course of this tumor is not yet fully described. Furthermore, there is no consensus on the standard operative procedure for this tumor. Material and Methods: Medical records of thirty-two patients, who underwent surgical resection of pulmonary sclerosing hemangioma from 1996 to 2007, were retrospectively reviewed. Results: Nineteen patients underwent lobectomy and thirteen patients underwent limited resection. Video-assisted thoracoscopic surgery was performed in 9 patients in the latter group. Lymph node dissection was done in 21 patients, and one patient was found to have lymph node metastasis of the tumor. There was no postoperative complication, no early death and no tumor-related late mortality. The mean follow-up duration was 39.3 months (2 months~129 months), and all patients were free of local recurrence and distant metastasis during this period. There was no significant difference in patient's characteristics between the two groups, except that the mean hospital stay was shorter in limited resection group than in lobectomy group (p=0.0031). Conclusion: Pulmonary sclerosing hemangioma usually requires surgical resection for both diagnosis and treatment. Limited resection can decrease hospital stay with a surgical outcome comparable to lobectomy, and may be preferred to lobectomy if sufficient resection margin can be achieved.

• 대한세포병리학회지
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• 제9권2호
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• pp.193-199
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• 1998

Sclerosing hemangioma is a rare, benign neoplasm of the lung, usually presented as a solitary pulmonary nodule in an otherwise asymptomatic middle-aged woman. Cytologically it shows papillary, sheet, and cyst-like arrangements representing three main histologic patterns of papillary, solid, and angiomatous ones, respectively. Herein, we report the fine needle aspiration cytology of 5 cases of sclerosing hemangioma of the lung. The most characteristic finding is cyst-like spaces Intimately related to the papillary or solid cell nests. The tumor cells are relatively monotonous round to oval, small to medium in size. They have small amount of eosinophilic cytoplasm. The nuclei are uniform, round and have small but conspicuous nucleoli. The tumor cells in one of the presenting cases are large with abundant cytoplasm and show moderate nuclear pleomorphism. The nuclear chromatin, however, is fine and even without exception, even in the case showing nuclear pleomorphism. Major differential diagnoses based on the cytologic findings are well-differentiated papillary adenocarcinoma, bronchioloalveolar carcinoma, and carcinoid tumor.

• Journal of Chest Surgery
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• 제54권6호
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• pp.528-531
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• 2021

Pulmonary sclerosing pneumocytoma (PSP) is a tumor of pneumocytic origin that is classified as a benign neoplasm. To date, aggressive behavior of this tumor has rarely been reported. Here, we describe a case of a 56-year-old woman with a huge, 19-cm PSP that resulted in mediastinal shift and showed microscopic endobronchial invasion and necrosis. The differential diagnosis included malignant mesenchymal tumors, such as solitary fibrous tumor; however, PSP was confirmed based on the characteristic thyroid transcription factor 1 positivity and membranous expression of Ki-67 on immunohistochemical staining of tumor cells.

• 대한세포병리학회지
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• 제15권2호
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• pp.101-105
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• 2004

Fine needle aspiration (FNA) cytological examination is an appropriate method for the evaluation of pulmonary nodules. In major types of lung cancer, Its diagnostic accuracy is quite high. However, it is sometimes difficult, using this technique, to differentiate between some unusual phenotypes including adenosquamous carcinoma, bronchioloalveolar carcinoma (BAC), neuroendocrine tumor, mucoepidermoid carcinoma, and sclerosing hemangioma. Here, we present a case involving extremely well differentiated adenosquamous carcinoma, mimicking benign lesions, such as pulmonary scar and adenomatoid malformation with squamous metaplasia. The patient was a 68-year-old man presenting with a solitary pulmonary nodule$(1.6\times1.6cm)$, which was incidentally found at the periphery of the right lower lobe. FNA revealed some clusters of glandular cells with minimal atypia, in addition to squamous cells at a nearly full maturational state. Histological examination verified the cytological diagnosis on a lobectomy specimen. The tumor exhibited a well differentiated adenocarcinoma component, mimicking the bronchioles in scarred lung tissue. and a well differentiated squamous cell carcinoma component, mimucking the squamous cell nests of adenoacanthoma, in the other organs. In the present case, the possibility of adenosquamous carcinoma should have been considered if squamous cells were seen in the FNA from the peripheral pulmonary nodule, even though they appeared to be benign.

• Journal of Chest Surgery
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• 제26권3호
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• pp.236-240
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• 1993

Video thoracoscopic surgery is a new modality that gains acceptance rapidly from thoracic surgeons. We have experienced two left lower lobectomies, one left upper lobectomy & one right upper lobectomy with using video thoracoscopy for the four patients with lung parenchymal disease from July 1992 to February 1993. The post-operative courses were uneventful. The final pathologic diagnosis were sclerosing hemangioma, adenocarcinoma, bronchiectasis, leiomyoma & the post-operative courses were short. These patients needed less analgesics because postoperative pain was reduced markedly, and hospitalization was shortened due to rapid recovery. We would like to prefer video thoracoscopic lobectomy to the lobectomy through standard thoracotomy in uncomplicated patients with simple pulmonary parenchymal diseases.

• Journal of Chest Surgery
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• 제14권4호
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• pp.345-349
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• 1981

Pulmonary hamartoma is relatively common among the benign tumors of lung, and is credited to Albrecht who In 1904 described a disorganized arrangement of tissue normally present In an organ. But hamartoma has rare incidence of total pulmonary tumors, and especially endobronchial origin is extremely rare. We have experienced three cases of pulmonary hamartoma Including one bronchial origin. First case was a 27 years old woman who had multiple hamartomas, located all in right middle lobe and middle lobectomy was performed. Second case, a 56 years old woman, had endobronchial hamartoma, l x l .5x l .8cm in size and located at right intermediate bronchus. Right pneumonectomy was Inevitable because of It`s proximal location near the hilum. Third case, a 55 years old man, revealed sclerosing hemangioma microscopically, 4x4x5 cm In size, in right lower lobe and right lower lobectomy was performed. Postoperative course of all of them were uneventful and discharged with good general condition on the ~ 4th to 26th day postoperatively.

• Tuberculosis and Respiratory Diseases
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• 제40권4호
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• pp.384-389
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• 1993

연구배경 : 폐 경화성혈관종은 중년 여성에서 호발하며 양성 폐종양 중 2번째로 많은 빈도를 보이나 국내에서는 이제까지 이에 대한 간헐적인 연구보고가 있었다. 방법 : 저자들은 1985년 1월부터 1993년 4월까지 연세대학교 의과대학 세브란스병원에서 절제수술로서 확진된 폐 경화성혈관종 8예에 대하여 임상기록과 함께 방사선학적, 조직병리학적 소견 등을 후향적으로 조사하였다. 결과 : 상기 조사기간중 본원에서 폐종양으로 수술받은 총 381명의 환자중 폐 경화성혈관종은 양성종양 가운데 2번째의 발생빈도를 보였다. 환자는 남자 1명과 여자 7명이었고 수술당시 환자연령은 14세부터 63세로 평균 43.8세이었다. 호흡기 증상이 있어 진단된 경우는 2예뿐이며 대부분이 무증상군으로 6예에서 통상적인 흉부 X-선 촬영상 우연히 발견되었다. 흉부 X-선상 이상소견이 발견되어 수술로 확진되기까지의 평균기간은 7.9개월이었으며 수술전 양성종양으로 추정된 경우가 4예 있었고 나머지 4예는 악성 폐종양과의 감별을 요하였다. 수술은 5예에서 폐엽절제술, 1예는 폐엽 부분절제, 2예는 종괴적출만 시행되었다. 결론 : 저자들은 수술로 확진된 폐 경화성혈관종 8예를 임상 및 조직병리학적으로 분석한 결과 상기 종양이 비록 양성종양으로 분류되지만 드물게 림프절 전이나 다발성을 보인다는 사실과 수술전에 악성종양과의 감별이 쉽지 않으며 최근 폐 악성종양이 증가하고 있음을 고려할 때 수술은 진단 및 치료목적으로 필요하다고 생각된다.