• Mycobiology
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• 제37권3호
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• pp.230-237
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• 2009

The oyster mushroom (Pleurotus ostreatus) is one of the most important edible mushrooms worldwide. The mechanism of P. ostreatus fruiting body development has been of interest both for the basic understanding of the phenotypic change of the mycelium-fruiting body and to improve breeding of the mushrooms. Based on our previous publication of P. ostreatus expressed sequence tag database, 1,528 unigene clones were used in macroarray analysis of mycelium, fruiting body and basidiospore developmental stages of P. ostreatus. Gene expression profile databases generated by evaluating expression levels showed that 33, 10, and 94 genes were abundantly expressed in mycelium, fruiting body and basidiospore developmental stages, respectively. Among them, the genes specifically expressed in the fruiting body stage were further analyzed by reverse transcription-polymerase chain reaction and Northern blot to investigate temporal and spatial expression patterns. These results provide useful information for future studies of edible mushroom development.

• 한국전문물리치료학회지
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• 제16권3호
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• pp.50-59
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• 2009

The aim of the study was to evaluate the effectiveness of exercise therapy on physical function of patients with anklyosing spondylitis (AS) through the systemic review and meta-analysis. The 54 studies were identified from computerized search of published researches on PubMed, Embase, CINAHL, PEDro, KISS, KERIS database until February, 2008 and review of reference lists. The main search terms were the combination "ankylosing spondylitis", "exercise", "spondyloarthropathy and exercise", "ankylosing spondylitis and physical therapy". The subgroup analysis was performed by the publication year, quality score, type of disease, content of intervention, intervention provider, type of intervention, method of intervention, intervention period and the point of outcome measured. Two reviewers independently selected trials for inclusion, assessed the quality and extracted the data. The result was as follows: The 10 trials were eligible for inclusion criteria, then the systematic review and meta-analysis was assessed on effectiveness of exercise therapy. The meta-analysis of 10 studies based on the random effect model showed that the exercise therapy was beneficial in treating the diseases (effect size .55; 95% confidence interval -.3.75~.61). The findings suggest that the exercise therapy would be appropriate to manage the physical function of AS with evidence based on Meta-analysis. Therefore, the exercise therapy supervised by physical therapist should be recognized as the essential approach to manage the AS and necessarily recommended to improve physical function.

• International Journal of Knowledge Content Development & Technology
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• 제11권3호
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• pp.29-44
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• 2021

The study provides a quantitative and qualitative description of global research in the domain of quantum machine learning (QML) as a way to understand the status of global research in the subject at the global, national, institutional, and individual author level. The data for the study was sourced from the Scopus database for the period 1999-2020. The study analyzed global research output (1374 publications) and global citations (22434 citations) to measure research productivity and performance on metrics. In addition, the study carried out bibliometric mapping of the literature to visually represent network relationship between key countries, institutions, authors, and significant keyword in QML research. The study finds that the USA and China lead the world ranking in QML research, accounting for 32.46% and 22.56% share respectively in the global output. The top 25 global organizations and authors lead with 35.52% and 16.59% global share respectively. The study also tracks key research areas, key global players, most significant keywords, and most productive source journals. The study observes that QML research is gradually emerging as an interdisciplinary area of research in computer science, but the body of its literature that has appeared so far is very small and insignificant even though 22 years have passed since the appearance of its first publication. Certainly, QML as a research subject at present is at a nascent stage of its development.

• Journal of Preventive Medicine and Public Health
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• 제52권5호
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• pp.281-291
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• 2019

Objectives: The validity of instruments measuring socioeconomic position (SEP) has been a major area of concern in research on cardiovascular health disparities. The purpose of this systematic review is to identify the current status of the methods used to measure SEP in research on cardiovascular health disparities in Korea and to provide directions for future research. Methods: Relevant articles were obtained through electronic database searches with manual searches of reference lists and no restriction on the date of publication. SEP indicators were categorized into compositional, contextual, composite, and life-course measures. Results: Forty-eight studies published from 2003 to 2018 satisfied the review criteria. Studies utilizing compositional measures mainly relied on a limited number of SEP parameters. In addition, these measures hardly addressed the time-varying and subjective features of SEP. Finding valid contextual measures at the organizational, community, and societal levels that are appropriate to Korea's context remains a challenge, and these are rarely modeled simultaneously. Studies have rarely focused on composite and life-course measures. Conclusions: Future studies should develop and utilize valid compositional and contextual measures and appraise social patterns that vary across time, place, and culture using such measures. Studies should also consider multilevel influences, adding a focus on the interactions between different levels of intertwined SEP factors to advance the design of research. More attention should be given to composite and life-course measures.

• 대한한방내과학회지
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• 제42권3호
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• pp.308-322
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• 2021

Objectives: This study investigates the latest clinical studies on Korean medicine treatment of chronic subdural hematoma (CSDH) in China. Methods: A CNKI search investigated the last 10 years of clinical studies of Korean medicine treatments in Chinese medical journals for CSDH. The search focused on authors, publication years, types of studies, purposes of studies, methods and duration of treatment, evaluation criteria, and results of treatment. Results: In 19 studies, there were 14 randomized controlled trials (RCTs), 4 case series, and 1 case-control study. In all 19 studies, Korean medical treatment and Western treatment were combined. Herbal medicine was used in 19 studies and acupuncture treatment in 2 studies. The most frequently used prescription was Hyeolbuchukeo-tang-gagambang, and the most frequently used acupoint was PC6. In all 19 studies, the effectiveness of Korean medicine treatment performed in parallel with Western treatment was confirmed. Conclusions: In this study, Korean medicine combined with Western treatment for CSDH was effective. More clinical studies and case reports are required to develop a guided treatment for CSDH.

• Asian Journal of Innovation and Policy
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• 제11권2호
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• pp.258-276
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• 2022

The historical aspects, policies, institutions, awards and measurement results of scientific literacy and scientific culture development in Indonesia have currently attracted further exploration. This paper utilizes secondary data research, further analyzed by employing the Supplementary Analysis technique. The results revealed that the tradition of writing and publishing scientific journals in Indonesia has existed ever since the Dutch East Indies with the journal's publication entitled 'Natuurkundig tijdschrift voor Nederlandsch Indië' in 1850. To date, Indonesia has owned 5,990 nationally accredited journals. Policy support has been provided at the national and regional levels, despite limitations in cultivating literacy and reading habit. From the institutional perspective, Indonesia provides a wide array of public support, including the effort of the Ministry of Education and Culture for advocating the national literacy movement and the availability of a reference database and scientific access established by the National Library; the Indonesian Institute of Sciences, and the Ministry of Research and Technology. Similarly, in the award-related perspective, the Indonesia government has granted awards to individuals or groups and local governments engaging in the cultivation of scientific literacy and scientific culture. However, among the global measurements for literacy development in Indonesia (in 2020) recorded that three indicators scored less than those in 2019.

• 동의생리병리학회지
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• 제36권2호
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• pp.41-47
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• 2022

Postherpetic neuralgia(PHN) is one of the most common intractable chronic pain syndromes. This review was conducted to investigates the trends in recent clinical studies of PHN in China and to find out the efficacy of Chinese medicine treatment for PHN. Based on CNKI databases, nineteen randomized controlled trials(RCTs) were analyzed. The search focused on the authors, publication year, sample size, age, duration of illness, treatment period, lesion sites, methods, outcome measures, and results of the selected articles. Four studies used herbal medicine. The most frequently used herbs were Angelicae Gigantis Radix(當歸) and Corydalis Tube(玄胡索). Eighteen studies used acupuncture treatment. The most frequently used acupoints were ST36, LR3, LI4. Three studies used moxibustion and 5 studies used cupping treatment. In all nineteen studies, the efficacy of Chinese medicine treatments was confirmed. More varied and scientifically designed clinical studies are required to develop treatments for PHN. The results of current study could be used as guidance for further studies of treatment on PHN.

• 한방재활의학과학회지
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• 제33권1호
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• pp.31-45
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• 2023

Objectives The aim of this study is to find the future perspective through analyzing the trends of acupuncture treatment for gouty arthritis (GA) by searching the China National Knowledge Infrastructure (CNKI) and PubMed. Methods We searched clinical studies about acupuncture treatment for GA through the searching the electronic database of CNKI and PubMed. We analyzed the characteristics of selected studies according to research design, sample size, publication year, treatment methods, evaluation criteria and adverse events. Results Twenty-nine studies published from January 1, 2015 to July 1, 2022 were selected. They consisted of 25 randomized controlled trials, 3 non-randomized controlled trials, and 1 case reports. In these studies, several types of acupuncture treatments were performed and the most treatment was conventional acupuncture treatment with fine needles. The most commonly used evaluation outcome was effective rate. Conclusions Through this result, the Chinese literature positively reported the effect of acupuncture on GA. However, high-quality evaluation by rigorous research using well-designed and more objective outcomes is required.

• Asian Journal of Innovation and Policy
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• 제12권1호
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• pp.131-154
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• 2023

This study investigates the productivity of Indonesian social scientists during the COVID-19 pandemic, with a particular concentration on their contributions to COVID-19 prevention and management. By categorizing social science research according to themes such as authors' gender, authors' institution of origin, forms of collaboration, and journal quality, this study examines the patterns and factors that influence research output. Using information from the Scopus database, 1,071 journal articles were analyzed in total. The findings indicate that collaborations with foreign researchers considerably improve productivity and publication quality, with Malaysian and Australian institutions serving as the most active partners. Nevertheless, there are gender disparities, as female authors write and are cited less frequently than male authors. The study stresses the importance of increasing international collaboration among Indonesian authors and implementing affirmative action policies to support and empower female researchers. This study contributes to the existing body of knowledge by providing policymakers, funding agencies, and academic institutions with recommendations for fostering a more inclusive and influential research environment in Indonesia.

• 연구윤리
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• 제4권2호
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• pp.1-5
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• 2023

Purpose: There are already hundreds of millions of users of the Metaverse platform, and within a few years, it is expected to develop into a stage for new economic activities with huge industrial ripple effects due to the size of users. The purpose of this study is to derive considerations for the development of metaverse ethical guidelines. Research design, data, and methodology: The concept of the metaverse was examined through various opinions of industry and experts on the metaverse, and literature related to metaverse ethics was analyzed in the Korean journal database. Results: Six issues were identified through the existing research. (1) Establishing a unified definition of metaverse (2) Necessity of establishing ethical principles considering the operator (3) Personal information protection and privacy (4) Expression in a virtual environment (5) Copyright and intellectual property rights of creations (6) Virtual economy and fairness of trade. Conclusions: Metaverse ethics will be developed and implemented in a form and method different from the real world, but basically, continuous discussions on ethical rationality are needed in the process. In addition, since the ethical judgment in the metaverse environment accompanies cultural differences and epochal changes, it is necessary to focus on metaverse ethics cases.