• Land and Housing Review
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• v.13 no.2
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• pp.81-90
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• 2022

This study is based on social needs for green healing spaces assumed to enhance mental health in a city. This study proposes development directions through the analysis of modern social recognition factors for neighborhood gardens. As a research method, web information data was collected using Textom among big data tools. Text Mining was conducted to extract elements and analyze their relationship through keyword analysis, network analysis, and cluster analysis. As a result, first, the healing space and the healing environment were creating an eco-friendly healthy environment in a space close to the neighborhood within the city. Second, neighborhood gardens included projects and activities that involved government, local administration, and citizens by linking facilities as well as living culture and urban environments. These gardens have been reinforced through green welfare and service programs. In conclusion, friendly gardens in the neighborhood for the purpose of public interest, which are beneficial to mental health, are green infrastructures as a healing environment that can produce positive effects.

• The Journal of Korean Medicine
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• v.25 no.2
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• pp.138-150
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• 2004

Objectives : Alzheimer's disease (AD) is a geriatric dementia that is widespread in old age. In the near future AD will be the biggest problem in public health service. Although a variety of oriental prescriptions, including Sesim-tang, have been traditionally utilized for the treatment of AD, their pharmacological effects and action mechanisms have not yet been fully elucidated. The present study investigated the effects of Sesim-tang on apoptotic cell death induced by CT105 (carboxy terminal 105 amino acid peptide fragment of APP) overexpression in SK-N-SH neuroblastoma cell lines. Methods: We studied the regenerative and inhibitory effects on Alzheimer's disease in CT105-induced SK-N-SH cell lines by Sesim-tang water extract. We examined for cell morphological pattern, DNA fragmentation, LDH activity assay, zymography assay, and immunohistochemistric analysis. Additionally, we investigated the association between the CT105 and neurite degeneration caused by CT105-induced apoptotic response in neurone cells. Results: Findings from our experiments have shown that Sesim-tang inhibits the synthesis or activities of CT105, which has neurotoxicities and apoptotic activities in the cell line. In addition, pretreatment with Sesim-tang ($>50\mu\textrm{g}/ml$ for 12 hours) partially prevented CT105-induced cytotoxicity in SK-N-SH cell lines. SK-N-SH cell lines overexpressed with CT105 exhibited remarkable apoptotic cell damage. Based on morphological observations by phase-contrast microscope and LDH activity measurements in the culture media, the CT105-induced cell death was significantly inhibited by Sesim-tang water extract. Sesim-tang was found to reduce the expression of APP and caspase-3 induced by CT105 in SK-N-SH cell lines and in rat hippocampus. Conclusions: As the result of this study, in the Sesim-tang group, apoptosis in the nervous system is inhibited, the repair against the degeneration of SK-N-SH cell lines by CT105 expression is promoted. Hence, Sesim-tang may be beneficial for the treatment of AD.

• Herbal Formula Science
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• v.13 no.1
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• pp.35-48
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• 2005

Alzheimer's disease(AD) is a geriatric dementia that is widespread in old age. In the near future AD will be the biggest problem in public health service. It has been widely believed that $A{\beta}$ peptide devided from APP causes apoptotic neurotoxicity in brain. However, recent evidence suggests that n99 may be an important factor causing neurotoxicity in AD. Mouse PC12 cells expressed with n99 exhibited remarkable apoptotic cell damage. We invesgated the protective effects of Gagamgobonhwan water extract(GKG). Findings from our experiments have shown that GKG inhibits the activities of CT99, which has neurotoxicities and apoptotic activities in cell line. In addition, treatment of GKG($75{\mu}g/ml$ 24 hours) partially prevented CT99-induced cytotoxicity in PC12 cells. As the result of this study, in GKG group the apoptosis in the nervous system was inhibited, the repair against the degerneration of PC12 cells by CT99 expression is promoted. Taken together, GKG exhibited inhibition of CT99-induced apoptotic cell death. GKG may be beneficial for the treatment of AD.

• Herbal Formula Science
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• v.13 no.1
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• pp.103-121
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• 2005

Alzheimer's disease(AD) is a geriatric dementia that is widespread in old age. In the near future AD will be the biggest problem in public health service. It has been widely believed that $A{\beta}$ peptide devided from APP causes apoptotic neurotoxicity in AD brain. However, recent evidence suggests that n99 may be an important factor causing neurotoxicity in AD. Mouse Neuro 2A cells expressed with CT99 exhibited remarkable apoptotic cell damage. We invesgated the protective effects of Ikgiansintang water extract(IGA). Findings from our experiment have shown that IGA inhibits the activities of CT99, which has neurotoxicities and apoptotic activities in cell line. In addition treatment of IGA($50{\mu}g/ml$ for 24 hours) partially prevented CT99-induced cytotoxicity in Neuro 2A cells. As the result of this study, In IGA group, the apoptosis in the nervous system is inhibited, the repair against the degerneration of Neuro 2A cells by n99 expression is promoted. Base on these findings, IGA may be beneficial for the treatment of AD.

• The Journal of Internal Korean Medicine
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• v.25 no.3
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• pp.482-491
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• 2004

Alzheimer's disease(AD) is a geriatric dementia that is widespread in old age. In the near future AD may be the biggest problem in public health service. Although a variety of oriental therapies in the study of Jimitang have been traditionally utilized for the treatment of AD, their pharmacological effects and active mechanisms have not been fully elucidated. This study in an investigation of effects of Jimitang on apoptotic cell death induced by CT105 overexpression in SK-N-SH neuroblastoma cell lines. DNA fragmentation, neurite outgrowth assay and LDH activity assay were examined. The regeneratory and inhibitory effects on Alzheimer's disease in pCT105-induced neuroblastoma cell lines by Jimitang water extract were examined. Findings from these experiments have shown that Jimitang inhibits the synthesis or activities of CT105, which has neurotoxicities and apoptotic activities in cell lines. In addition, pretreatment of $Jimitang(>50\;{\mu}g/mL\;for\;12\;hours)$ partially prevented CT(105)-induced cytotoxicity in SK-N-SH cell lines, and were inhibited by pretreatment. $Jimitang(>50\;{\mu}g/mL\;for\;12\;hours)$ repaired CT(105)-induced neurite outgrowth when SK-N-SH cell lines were transfected with CT(105). Results of this study show that. in the Jimitang group, the apoptosis in the nervous system in inhibited, the repair against the degerneration of neuroblastoma cells by CT105 expression is promoted. In addition, Jimitang was found to inhibit DNA fragmentation induced by CT105 overexpression, and promote neurite outgrowth. These findings suggest that Jimitang is beneficial for the treatment of AD.

• Journal of the Korean Society of Food Science and Nutrition
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• v.44 no.9
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• pp.1295-1303
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• 2015

Berry fruits are rich in phytochemicals, including polyphenols, anthocyanins, phenolic acids, and organic acids, which are known to have beneficial effects on health. The aim of this study was to investigate chemical composition, functional constituents, and antioxidant activities of mulberry, black raspberry, raspberry, and blueberry cultivated in Korea. Acidity of the four berries ranged from 0.26% to 1.10%, and pH ranged from 3.3 to 5.2. Total mineral contents of the four berries ranged from 92.9 to 256.0 mg/100 g. Among the berries, mulberry contained the most abundant total free sugars, and glucose and fructose were the major sugars in the berries. Mulberry contained more than three times as much ${\gamma}-aminobutyric$ acid as the content of the other berries. Blueberry contained more free phenolic acid than the other berries. Especially, chlorogenic acids were the major free phenolic acids in blueberry. Black raspberry had the highest amount of polyphenols, anthocyanins, and flavonoids among the berries and showed the highest antioxidant activity.

• Journal of the Korean Institute of Landscape Architecture
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• v.49 no.5
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• pp.138-150
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• 2021

This study aims to understand the background and characteristics of the UK's allotments, as the UK is one of the nations participating in allotment invigoration. This study will focus on approaches to policy, active governance, and socioeconomic impact. To address this, allotment-related issues, policies since the beginning of the 19th century were analysed. In addition to this, Sheffield City, UK, was selected as a specific case to analyse the framework of allotment management, active governance concerning allotment management, and the residents' perceptions of allotments through a questionnaire survey. It was found first that the UK government, since 1806, has been consistently producing localism policies aiming to devolve management authority into local governments, which actively obtain sites for allotments. Secondly, the structure of allotment management formed in active governance leads the overall maintenance, partnership, income generation, and monitoring of the allotments. Interestingly, the structure of the department organisation of local government in Sheffield established the position of community manager, who encourages community invigoration. However, a gap between socioeconomic aspects was found in which the allotment invigoration in lesser deprived areas outweighs the invigoration in more deprived areas. In contrast, according to the questionnaire survey, respondents in more deprived areas were more likely to be involved in allotment activities and the community. The key to addressing the socioeconomic gap in the context of allotment invigoration is the adoption of the Public-Community-Private-Partnership framework. This will be of great importance to longer-term promotion of beneficial allotment practices.

• Journal of Korea Entertainment Industry Association
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• v.13 no.6
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• pp.53-67
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• 2019

This study is expected to be of significance in that it attempted to examine the personal information protection awareness of college students and the state of their personal information protection as prospective information processors and private information owners to boost their will to put private information protection in practice. As a result of making an analysis, the most common average time that the students spent in doing every online activity on weekdays was fewer than two or three hours, and the most dominant activities that they did over the Internet were for entertainment or hobbies. As for awareness of the nature of the Internet, they looked upon it as a quite open public space. Regarding the state of private information protection, they thought that changing passwords on a regular basis would be beneficial to personal information protection, and many thought that it's needed to withdraw from or shut down web sites that weren't used for a long time. In terms of actual practice, however, they didn't change their e-mail passwords regularly on the grounds that it's a hassle, and even the students who had experience of personal information leakage didn't report it or didn't ask for counsel on the grounds that they didn't want to be bothered as well. The majority of the students weren't cognizant of how to report or seek counsel. In the future, personal information protection should be educated on a continual basis as part of curriculum to raise awareness of it among students and boost their will to practice it with a sense of responsibility in an effort to prevent the occurrence of collateral damages triggered by personal information leakage.

• The Journal of the Korea Contents Association
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• v.7 no.10
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• pp.311-320
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• 2007

This study is to analyze the present condition of internal dance troupes' web sites contents and through this study, we aim at suggesting beneficial plans not only for constructing better web sites and contents for national dance troupes but also for contributing to the development of national dance troupes. In order to achieve this study's object, we selected eight dance troupes that run their own web sites and examined their contents. the conclusions are as following. First, among internal professional dance troupes, Korea National Ballet, Seoul Ballet Theatre and Universal Ballet Company offer the best contents at their home pages and they have the most lively community concerned activities at their internet web sites. Second as for the web sites of municipal(provincial) dance troupes, those of Gyeonggi provincial dance troupe, Daejeon municipal dance troupe, Busan municipal dance troupe, Seoul municipal dance troupe Incheon municipal dance troupe have lots of contents briskly carried on, but those of the others need complementary measures. Third, Seoul ballet theatre and Universal Ballet Company offer lots of information about their activities to satisfy their customers and make the maximum use for public relations ; performance news, the introduction of their members, the story of ballet press reviews, new letters. On the other hand, at the web sites of Metropolitan Dance Theater Provincial Dance Company, there are much fewer contents about their activities which doesn't lead customers to visit their webs.

• Journal of Digital Convergence
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• v.14 no.5
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• pp.427-432
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• 2016

The purpose of this study was to investigate drowning death patients on clinical care and prevention. Drowning accidents that occurred in the Republic of Korea were identified by using the Emergency Activity Daily Report Data from the National Emergency Management Agency (NEMA). The age of drowning accidents was 20-29 years (25.4%). Drowning cases for the months of August was 17.6%. The main circumstance involved in the drowning cases was swimming (45.0%). Half of swimming incidents related the drowning accidents of people attempting to save a life of a family member or friend from the water. The most common location was at a lake or reservoir (40.2%). Drowning is a main cause of accidents in the Republic of Korea. Preventive strategies that may be beneficial for persons contain life jackets or life rings supply, upgrading swimming ability, placing lifeguards based on public education activities.