• Journal of Yeungnam Medical Science
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• 제13권2호
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• pp.261-271
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• 1996

저자들은 1992년 1월 1일부터 1995년 6월 30일까지 영남대학병원에서 양에너지 방사선 골밀도 측정기로 요추 골밀도를 측정한 자연적 폐경기 여성 136명을 대상으로 설문과 의무기록지를 검토하여 연령, 신장, 체중, 초경 및 폐경 연령, 자녀수, 모유수유 자녀수, 경구 피임력, 골다공증의 가족력, 우유 및 커피섭취량, 흡연 및 음주력 그리고 신체활동량을 평가하였다. 평균 연령은 55.2세였고, 평균 폐경 연령은 47.9세였다. 골밀도는 신장, 체중 그리고 신체활동량과 유의한 양의 상관관계를 보였고, 나이, 폐경 후 기간 그리고 자녀수와는 유의한 음의 상관관계를 보였다. % age-matched 골밀도는 나이, 신장, 체중, 신체활동량 그리고 폐경 후 기간과 유의한 상관관계를 보였다. 골밀도를 종속변수로 한 다중회귀분석에서는, 폐경 후 기간, 신체활동량 그리고 체중이 골밀도에 영향을 주는 유의한 변수였고, 그 중 폐경 후 기간이 가장 영향을 주는 변수였다. 나이의 효과를 통제하기 위해 % age-matched 골밀도를 종속변수로 한 다중회귀분석에서는, 신체활동량과 체중이 % age-matched 골밀도에 영향을 주는 유의한 변수였고, 신체활동량이 가장 영향을 주는 변수였다. 그 결과 폐경기 여성의 골밀도에 영향을 미치는 인자들 중 나이의 영향을 배제하면 신체활동량과 체중이 중요한 인자로 생각된다. 그러므로 지속적인 신체활동이 골다공증의 예방에 중요하다는 것을 알 수 있었다.

• 한국산학기술학회논문지
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• 제21권8호
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• pp.325-333
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• 2020

본 연구의 목적은 기존 자동심장충격기인 T-AED와 새롭게 개발된 SC-AED의 제세동 신속성 및 사용자가 느끼는 주관적 편의성을 비교하는 것이다. 2017년 2월부터 2018년 4월까지 전남지역의 D대학, C대학병원의 기본인명소생술 교육센터에서 의료종사자 및 일반인을 위한 기본소생술과정에 참여한 156명을 T-AED (n = 77) 및 SC-AED (n = 79) 그룹에 무작위할당 하였다. 각 그룹은 제세동을 실시한 후, 총 제세동 지연시간, 제세동 지연시간, 쇼크버튼 누름 지연시간, 후속 흉부압박 재개시간까지의 시간을 측정하였고 이를 t-검정을 통해 분석했다. 실험 후 조작자신감, 사용편의성, 의사결정 도움, 이상 3가지 요인에 대한 자료를 설문으로 수집하였고 각각 t-검정을 통해 분석하였다. SC-AED는 T-AED와 비교하여 총 제세동 지연시간(11.22 초), 제세동 지연시간(11.04 초) 및 쇼크버튼 누름지연시간(2.15 초)가 현저히 단축되었습니다 (p<0.001). 주관적 편의성 측면에서 자신감(T-AED : 7.62±1.25VAS vs. SC-AED : 7.80±0.98VAS, p = .358)는 중요하지 않았지만, 편의성(T-AED : 7.05±1.36VAS vs. SC) -AED : 8.95±0.89VAS, p<0.001) 및 의사결정도움(T-AED : 6.58 ± 1.73VAS vs. SC-AED : 9.08±0.98VAS, p = 0.001)은 유의한 차이를 보여주었다. 결론적으로 T-AED에 비해 의료종사자 및 일반인 집단 모두에서 더욱 신속한 제세동을 가능하게 하였으며, 사용자의 편의성과 명확한 의사결정을 크게 도와주었다. SC-AED에 적용된 기술이 향후 보편적인 자동심장충격기에 상용화된다면 더욱 효과적인 PAD를 통해 심정지 환자의 생존율 제고에도 이바지할 것이다.

• Clinical and Experimental Reproductive Medicine
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• 제46권4호
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• pp.152-165
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• 2019

Objective: This study aimed to examine the effect of vitrification on apoptosis and survival in human preantral follicles after thawing. Methods: This experimental study was conducted at an acute tertiary care hospital from March 2012 to April 2013. Ovaries were sliced into 5 × 5 × 1-mm pieces and divided into the following three groups: preantral follicle isolation, ovarian tissue vitrification-warming followed by follicle isolation, and immunohistochemistry of fresh ovarian tissue. For statistical analyses, the Student t-test, chi-square test, Kruskal-Wallis test, and Kaplan-Meier survival analysis were used. Results: A total of 161 preantral follicles (70% secondary) were collected from ovarian cortex tissue of six women between 30 and 37 years of age who underwent oophorectomy due to cervical cancer or breast cancer. There were no significant differences in the follicular morphology of fresh preantral follicles and vitrified follicles after thawing. The mean Fas ligand (FasL) mRNA expression level was 0.43 ± 0.20 (relative to β-actin) in fresh preantral follicles versus 0.51 ± 0.20 in vitrified follicles (p= 0.22). The mean caspase-3 mRNA expression level in fresh preantral follicles was 0.56 ± 0.49 vs. 0.27 ± 0.21 in vitrified follicles (p= 0.233). One vitrified-thawed secondary follicle grew and developed to an antral follicle within 6 days of culture. Conclusion: Vitrification did not affect preantral follicle morphology or mRNA expression of the apoptosis markers FasL and caspase-3. Further studies are required to establish whether vitrification affects the outcomes of in vitro culture and the maturation of preantral follicles.

• 한국병원경영학회지
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• 제6권3호
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• pp.69-89
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• 2001

This study is focused that the electronic commerce(EC) on the purchasing section may improve the efficiency and transparency of the hospitals management. After reviewing the purchasing activity of hospitals, I study the introduction, expected effects, and problems of EC. So, I am going to provide basic information for activating EC. The samples are managers of 170 hospitals, which are located on Seoul. As a result of collection this survey, I analyze 79 hospitals. For data analysis, I use $X^2$-test and ANOVA for purchasing management and the relevance of EC according to the level of care. The results of this study are 1. The problems on the management of purchasing section are: firstly, they don't have sufficient time to study market. Secondly, it is difficult to find competitive suppliers. And, lastly, they cannot gather a lot of information about the price of products. 2. There are many answers of the needs on the introduction of B2B. However, some hospitals think they don't need it. But, the most answers are that the EC will be settled within 4 years. So, we can realize that these hospitals are getting interested on the EC. On the other hand, I find that they prefer outside EC companies for the introduction of EC. 3. On the expected effects on EC, first is the effectiveness of the market survey. The next is to collect information of adequate price of products owing to clear transaction, find easier new suppliers and gather useful data. 4. On the external problems of the introduction of EC, there is low credibility related to the security and the weakness of suppliers' information system. Especially, on the Real Transaction Price Payment system, the bigger bed size, the higher understanding on these problems. On the internal problems of the introduction of EC, first is the burden of the introduction of EC and operating cost. Especially, on the burden of the disclosure of revenue source, the smaller bed size, the higher understanding on this problem So, this is a point which deserves my attention statistically. However, this shows relatively little understanding about incomplete the standard of product category and the weak information system of hospital. Through this study, I am going to suggest 3 points for the activation of the introduction of EC on hospitals. 1. The reform of the Real Transaction Price Payment System on medical supplies and materials for medical treatment 2. The establishment of the standard of product category 3. The promotion of information system based on network.

• 대한간호학회지
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• 제2권1호
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• pp.115-129
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• 1971

As the result of a survey conducted by the author on the status of tile 12 educational institutions for mentally retarded children in Korea and their quartering facilities as well as on 934 children accommodated in such institutions, the following conclusion has been reached: 1) More than a half (approximately 58 percent) of the facilities for mentally retarded children are concentrated in Seoul. About eighty-three percent of these facilities are private establishments, of which 70 percent have their proprietors concurrently as their superintendents. Although these facilities were first established as many as 22 years ago, it has been only five or six years since education was actually started for mentally restarted children. 2) Out of a total of 179 employes, teachers number 99, there by constituting approximately 57.6 percent. Out of them, however, only 32 teachers or 2.8 percent have special teachers licenses. Thus, each teachers has to take care of an average of 29 children. This is excessive a number of children per teachers in view of the special nature of this education, there by indication how urgent it would be to secure more teachers lot this field. 3) Out of the mantally retarded children investigated 57.6 percent suffer from physical disorder in addition to mental retardation, 53.0 percent from mental alienation illnesses besides retardation, and 25 pent from physical, mental disorders in addition to retardation. It is therefore necessary to maintain medical and nursing facilities together with educational facilities. however, two places have no medical facilities at all, and four other places, without medical personnel, have to receive medical support from nearby hospitals or clinics. 4) The total number of children in the surveyed facilities is 934, who can be broken down into 58.7 percent boys and 41.3 percent for girls. They are classified into 12.5 percent for idiot, 37.7 percent for imbeciles, 32.7 percent for morons, and 17.3 percent for thoes children on borderline. Their average age is 13.9 years. 5) As the result of education, the illiteracy rate of mentally retarded children has decreased from 78.1 percent to 32.1 percent while the percentage of those taking the primary school course has increased for 12.2 per cent to 33.5 percent. As a result, it has been learned that education is definitely necessary for Retarded children though it may be a difficult task. 6) The children who have mentally retarded children among their brothers or sisters constitute 6.3 percent of the total number. The corresponding rate for boys is 3.5 percent while that for girls is a remarkably higher rate 10.6 percent. Through studies on the causes of their mental retardation, it has been learned that 39.6 percent of them is of the inherent type and 35.3 percent is of the environmental type. Control and improvement of health of mothers and children, early diagnosis and early treatment are believed to be very important because they could prevent or alleviant much of these conditions. 7) The storage age of teachers and employes is 35.3 years, an indication that a great proportion of them is experienced in a way or another as their major difficulty or problems in serving with these special school, 22.5 percent cited inadequate payment 24.5 gave the inadequate public understanding, and 22.5 percent pointed out the lack of understanding on the part of give parents.

• Journal of Preventive Medicine and Public Health
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• 제25권2호
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• pp.115-126
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• 1992

우리나라 일부지역의 암사망률을 추정하기 위하여 경상남도지역을 대상으로 조사연구를 시행하였다. 조사대상연구는 공무원및교직원의료보험공단 경상남도지부 피보험자 및 피부양자들이며, 이들중 1989년 1월부터 1990년 12월까지의 사망자 3,867명에 대하여 사망원인을 조사하였다. 사망원인의 확정은 사망진단서 및 의료보험공단의 전산화된 의료기관 이용자료를 기본자료로 3단계에 걸쳐 시행하였다. 사망진단서를 이용한 1차조사, 의료기관 이용자료를 이용한 2차조사, 가족설문조사인 3차조사를 시행한 결과 암질환으로 인한 사망자는 990명이었다. 사망원인이 암질환인 사망자 990례를 분석하여 우리나라 경상남도지역의 암사망률 및 부위별 암사망률을 추정하였다. 우리나라 경상남도지역 암질환의 조사망률은 10만 인 년당 남자 138.7, 여자 65.7으로 추정되었다. 또한 부위별 암사망률의 순위는 남자의 경우 위암, 간암, 폐암, 식도암, 조혈기계 암의 순이었으며, 여자는 위암, 폐암, 간암, 유방암, 자궁경부암의 순으로 나타났다.

• Journal of Preventive Medicine and Public Health
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• 제21권2호
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• pp.207-216
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• 1988

Premature rupture of membrane is the most frequent cause of low birth weight infant delivery which increase the maternal and fetal morbidity and perinatal mortality. A retrospective case-control study was performed on 315 mothers who delivered low birth weight infants($\leq$2.5kg) with premature rupture of membrane and as control group 546 mothers who delivered normal birth weight infants(2.9-3.7kg) without premature rupture of membrane were chosen. The results obtained from this study were as follows: 1. The proportion of low birth weight infants due to premature rupture of membrane among all low birth weight infant deliveries was 14.5%, and this is equivalent to 1.1% among all deliveries. 2. The most significant maternal risk factor of low birth weight infant deliveries with premature rupture of membrane was infections on vagina, cervix and uterus during pregnancy. Compared with control, adjusted odds ratio was 7.61(95% confidence interval(CI) 1.88-30.88, p=0.004). Other significant maternal risk factors were the history of induced abortion, spontaneous abortion, and the experience of premature delivery. The risk ratios were 1.82, 2.07, 4.42, respectively. 3. Breech presentation did increase the risk of low birth weight infant delivery with premature rupture of membrane compared with control(Adjusted Odds ratio=2.66, 95% CI 1.35-5.26, p=0.005). 4. Mothers who had not taken antenatal care were having higher risk of low birth weight infant delivery with premature rupture of membrane against control(Adjusted odds ratio=1.73, 95% CI 1.19-2.53, p=0.004). These study results show that maternal factors such as the infection of genital organs during pregnancy, the history of induced abortion and breech presentation are significantly associated with the premature rupture of membrane in the low birth weight deliveries, and that most of these risk factors are controllable ones through proper antenatal cares.

• 한국물환경학회지
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• 제25권3호
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• pp.441-451
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• 2009

To evaluate the soil erosion best management practices, many computer models has been utilized over the years. Among those, the USLE and SWAT models have been widely used. These models estimate the soil erosion from the field using empirically-based USLE/MULSE in it. However, these models are not good enough to estimate soil erosion from highland agricultural watershed where severe storm events are causing soil erosion and muddy water issues at the receiving watersheds. Thus, physically-based WEPP watershed version was applied to a watershed, located at Jawoon-ri, Gangwon with very detailed rainfall data, rather than daily rainfall data. Then it was validated with measured sediment data collected at the sediment settling ponds and through overland flow. In this study, very detailed rainfall data, crop management data, soil data reflecting soil reconditioned for higher crop production were used in the WEPP runs. The $R^2$ and the EI for runoff comparisons were 0.88 and 0.91, respectively. For sediment comparisons, the $R^2$ and the EI values were 0.95 and 0.91. Since the WEPP provides higher accuracies in predicting runoff and sediment yield from the study watershed, various slope scenarios (2%, 3%, 5.5%, 8%, 10%, 13%, 15%, 18%, 20%, 23%, 25%, 28%, 30%) were made and simulated sediment yield values were analyzed to develop appropriate soil erosion management practices. It was found that soil erosion increase linearly with increase in slope of the field in the watershed. However, the soil erosion increases dramatically with the slope of 20% or greater. Therefore special care should be taken for the agricultural field with slope greater than 20%. As shown in this study, the WEPP watershed version is suitable model to predict soil erosion where torrential rainfall events are causing significant amount of soil loss from the field and it can also be used to develop site-specific best management practices.

• 한국산학기술학회논문지
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• 제20권12호
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• pp.110-116
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• 2019

Probiotics와 다양한 병원성 미생물간의 혼합배양에서의 길항적 억제효과를 조사하기 위해 2016년 1월부터 12월까지 국내 김치로부터 다양한 probiotics 균주를 분리하여 16S rRNA sequencing을 통한 계통학적 분석을 통해 140주의 프로바이오틱스를 동정하였다. 이중 항균력이 우수한 probiotics 4종(Enterococcus faecalis, Lactobacillus plantarum, Lactobacillus rhamnosus, and Lactobacillus reuteri )과 병원성 미생물 6종 (Candida albicans, Salmonella Enteritidis, E. coli O157:H7, Shigella flexneri, Staphylococcus aureus, and Pseudomonas aeruginosa)간의 혼합배양에서의 길항적 억제시험에서 probiotics 균주들은 대부분 배양 후에 균수가 정상적으로 크게 증가했지만 C. albicans를 포함하여 대부분의 병원성미생물들은 S. Enteritidis 를 제외하고 거의 완전하게 성장이 억제되었다. 이러한 in vitro 에서의 길항적 억제효과는 생성된 젖산과 유기산등의 낮은 pH에 의한 효과인 것으로 생각된다. 이상의 결과로 한국 김치에서 분리된 probiotics 균주 4종은 여성질염, 대장 및 피부관리 관련 치료제로써의 개발 가능성이 매우 큰 것으로 생각되며 향후 이러한 치료제는 probiotics 관련 국민건강 및 보건향상에 크게 기여할 것으로 생각된다.

• 한국산학기술학회논문지
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• 제18권12호
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• pp.485-493
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• 2017

양육지식은 양육실천에 중요한 관련요인이며 양육지식과 양육실천 정도 사정은 영아기 부모에게 중요하다. 저자는 기 개발된 타당성이 검증된 양육지식 척도(CRKS)와 양육실천 척도(CRPS)의 자국내 도입을 위하여 Saramma와 Thomas가 기 개발한 도구들을 채택하였다. 예비연구가 국제적 언어학적 검증단계에 따라서 수행되었다. 조사대상자는 A의 보건소와 B의 오케타니 마사지실을 방문한 영아 부모 20명이었다. 수집된 자료는 기술통계와 Wilcoxon Rank Sum Test가 도구의 이해도와 일반적 특성에 따른 도구의 평균 정도를 비교하기 위해서 사용되었다. 도구의 신뢰도와 타당도는 Cronbach's alpha, Spearman Correlations을 사용하였다. 대상자의 평균 나이는 33.94(${\pm}2.99$)세였고 영아의 평균 월령은 3.35(${\pm}0.58$)개월였다. CRKS와 CRPS의 이해도는 각각 1.80(${\pm}0.65$)점과 1.33(${\pm}0.54$)점으로 사용하기 쉬웠다. CRKS의 평균점수는 22.50(${\pm}4.89$)점으로 중간점수였고 CRPS의 평균점수는 30.75(${\pm}2.04$)점으로 높았다. CRPS의 Cronbach's alpha는 식이영역이 0.71, 성장과 발달 영역이 0.64, 청결과 보호영역이 0.68, 영아자극 영역이 0.77였다. CRPS의 영아자극과 CRKS의 성장과 발달 영역은 유의한 상관관계가 있었다(r=.530, p=.016). 일반적 특성 중에서 의료인이 비의료인에 비해서 유의하게 CRKS 점수가 높았다(p=0.04). CRKS와 CRPS 척도는 지역사회와 임상실무에서 사용이 간편하고 쉽게 응답할 수 있는 도구로 사용되기를 기대한다.