• Title/Summary/Keyword: Pt-Pd

Search Result 434, Processing Time 0.028 seconds

Effects of Panax Ginseng on the Development of Morphine Tolerance and Dependence

  • Kim, Hack-Seang;Oh, Ki-Wan;Park, Woo-Kyu;Shigeru Yamano;Satoshi Toki
    • Proceedings of the Ginseng society Conference
    • /
    • 1987.06a
    • /
    • pp.38-46
    • /
    • 1987
  • The present study was undertaken to determine the inhibitory effects of orally administered ginseng saponins (GS), protopanaxadiol saponins(PD) and protopanaxatriol saponins(PT) on the development of morphine induced tolerance and physical dependence in mice, and to determine the increases in the loss of morphine tolerance and dependence. The study also sought to determine the hepatic glutathione contents, which are closely related to the degree of detoxication of morphinone, a novel metabolite of morphine, and the effects of ginseng saponins on morphine 6-dehydrogenase. The results of the present study showed that GS, PD and PT administered orally inhibited the development of morphine-induced tolerance and dependence. GS, PD and PT, however, increased the loss of morphine tolerance and dependence. GS, PD and PT inhibited the reduction of hepatic glutathione concentration in mice treated chronically with morphine, and the activity of morphine 6-dehydrogenase. So we hypothesized that these results were partially due to the dual action of the test drugs, the inhibition of morphine production and the activation in morphine-glutathione conjugation due to the increased glutathione level for detoxication.

  • PDF

Improvement of $CO_2$Decomposition by Impregnating Noble Metals to Nano-size (Ni, Zn)-ferrites (귀금속 첨가에 의한 나노 (Ni, Zn)-페라이트의 $CO_2$분해 향상)

  • Kim, Jeong-Sik;An, Jeong-Ryul;Gang, Gye-Myeong
    • Korean Journal of Materials Research
    • /
    • v.11 no.10
    • /
    • pp.846-850
    • /
    • 2001
  • In the present study, nano-size powders of ternary ferrites, $Ni_{0.5}Zn_{0.5}Fe_2O_4$, as the potential catalysts of $CO_2$decomposition, were prepared by the wet processing of hydrothermal synthesis and coprecipitation method, and the catalyzing effects of impregnation of the noble metals, Pt and Pd, onto $Ni_{0.5}Zn_{0.5}Fe_2O_4$for the $CO_2$decomposition were investigated. XRD results of the synthesized ferrites showed a typical spinel structure of ferrite and the particle size was very small as about 6~10 nm. BET surface area of the ternary ferrites was not affected by the impregnation of Pt and Pd. The reactivity of the $CO_2$decomposition to carbon was improved by the impregnation of the noble metals of Pd and Pt. The effect of Pd-impregnation on the $CO_2$decomposition rate was higher than Pt-impregnation.

  • PDF

Characteristics of Rh- Pd- Pt Three-Way Catalysts with Double-Layer Washcoat on the Hydrothermal Aging (이중층 워시코트 Rh-Pd-Pt 삼원촉매의 열적 열하에 따른 반응 특성)

  • Choi Byungchul;Jeong Jongwoo;Son Geonseog;Jung Myunggun
    • Transactions of the Korean Society of Automotive Engineers
    • /
    • v.14 no.1
    • /
    • pp.8-16
    • /
    • 2006
  • The research was conducted to characterize of Rh-Pd-Pt TWC with a double-layer washcoat for gasoline vehicle. The physical characteristics on surface of catalyst were inspected by BET, SEM and TEM. The characteristics of catalytic reaction were examined by the TPD/TPR and CO-pulse chemisorption. The catalyst $6Hx(0.35\times11\times3)$ showed superior conversion performance after hydrothermal aging process, which was due to small difference of the surface area between. the fresh and the aged catalyst. The CO-chemisorption and surface area were superior in the 600 cpsi catalyst than other catalysts, this catalyst also shown the higher conversion efficiency of the exhaust emissions. From the TPR test, the conversion performance of the aged catalyst was decreased by the agglomeration and sintering of the PM and metal oxides. From the TPD result, it was found that the NO chemisorption was happed on the bottom-layer washcoat with Pd, and the NO chemisorption was re-happened on the upper-layer washcoat with Pt and Rh in the desorption process.

Synthesis and Characterization of Square Planar Mixed-Ligand Complexes (Ⅰ) : Synthesis and Spectroscopic Property of M(S-S)(N-N) Type Complexes with Ni (Ⅱ), Pd (Ⅱ), and Pt (Ⅱ) (평면사각형 혼합 리간드 착물의 합성과 그 특성 (제 1 보) : Ni (Ⅱ), Pd (Ⅱ) 및 Pt (Ⅱ) 의 M(S-S)(N-N) 형 착물의 합성과 분광학적 성질)

  • O, Sang O;Jeong, Deok Yeong
    • Journal of the Korean Chemical Society
    • /
    • v.34 no.6
    • /
    • pp.593-599
    • /
    • 1990
  • A series of new, square planar, and mixed-ligand complexes of Ni(Ⅱ), Pd(Ⅱ), and Pt(Ⅱ) have been prepared. From the observation of electronic spectrum for the variation of the ligand substituents, the very intense absorption band in the visible range is by the electronic transition of dithiolene to diimine ligand, HOMO to LUMO. In the various solvent systems the IT band shows the similar behavior to IT transition of mixed-valence dinuclear complexes followed with Hush theory, happens rto dominently by the inner sphere charge transfer transition. The negative solvatochromism represents that the excited-state electric dipole is reduced or reversed by the electronic transition.

  • PDF

Effects of Panax Ginseng on the Development of Morphine Induced Tolerance and Dependence(III) -Effects of Protopanaxadiol Fraction and Prtopanaxatriol Fraction in Mice- (모르핀의 내성 및 의존성 형성에 미치는 인삼의 효과(III) -인삼의 Protopanaxadiol 분획 및 Protopanaxatriol 분획의 영향-)

  • 김학성;오세관;최강주;이해빈
    • YAKHAK HOEJI
    • /
    • v.29 no.4
    • /
    • pp.188-192
    • /
    • 1985
  • Protopanaxadiol (PD) fraction and protopanaxatriol (PT) fraction were separated from thebutanol fraction of panax ginseng roots. Each group of mice was injected with morphine hydrochloride (40 mg/kg s.c.) three times at 8 hr intervals for a period of 6 days. PD fraction and PT fraction were injected (25, 100 mg/kg i.p.) to mice 1 hr prior to the third morphine injection daily. Inhibition of morphine tolerance was evidenced by the increase in analgesic response to morphine hydrochloride (10mg/ kg i.p.) as estimated by the tail flick method. Inhibition of morphine tolerance by PT fraction was effective but there was no remarkable difference in inhibition of tolerance development between control group andPD fraction group.

  • PDF

Electrogeneration of Hypochlorite Ions using a Dimensionally Stable Anode-Type (Ti/PtPd(10%)Ox) Electrode

  • Teresa Zayas;Miriam Vega;Guillermo Soriano-Moro;Anabella Handal;Miguel Morales;Leonardo Salgado
    • Journal of Electrochemical Science and Technology
    • /
    • v.15 no.2
    • /
    • pp.268-275
    • /
    • 2024
  • The study examined the electrogeneration of hypochlorite ions (ClO-) via electrolysis of aqueous NaCl solutions using a dimensionally stable anode-type (DSA-type) electrode based on platinum and palladium oxides supported on titanium mesh (Ti/PtPd(10%)Ox). The electrogenerated ClO- was quantified on the basis of the absorption band at 292 nm (Aλ = 292) of the UV-Vis spectrum. The effect of initial pH, concentration of NaCl, cell potential difference and electrolysis time were investigated in this study. The results showed that the electrolysis of aqueous NaCl solutions increases the solution pH up to high values (≥ 8.0) that favor the formation of ClO- over chlorine or hypochlorous acid. The hypochlorite concentration increases significantly at pH values > 7.0 and shows a linear trend with increasing NaCl concentration and with increasing cell potential difference. When the cell potential and NaCl concentration are held constant, the maximum hypochlorite value during electrolysis depends on both the cell potential and NaCl concentration. The Ti/PtPd(10%)Ox anode favors the production of hypochlorite ions, making this anode a promising material for use in electrochemical oxidation of wastewater via an indirect mechanism.

Conversion and Aging Characteristics of Oxidation Catalyst for Natural Gas Vehicle with Lean-burn System (린번 천연가스자동차용 산화촉매의 정화 및 열화특성)

  • 최병철;윤성식;정종우
    • Transactions of the Korean Society of Automotive Engineers
    • /
    • v.11 no.2
    • /
    • pp.134-139
    • /
    • 2003
  • This study was carried out to investigate the aging and conversion characteristics of oxidation catalysts for a natural gas vehicle with lean-bum system. The conversion of $CH_4$ was observed over the various composition ratio of PMs(Precious metals) and washcoating methods. On the fresh catalysts, Pd affected on the activity of $CH_4$ at low temperature more than other PMs in Pd-only and Rh/Pd/Pt catalysts. The activity at low temperature increased as a mount of Pd increases. On the aged catalysts, the $CH_4$ conversion efficiency of Pd-only catalyst with mono-layer washcoat decreased more than that of the other catalysts of $CH_4$ conversion. It was observed that the thermal durability of Rh/Pd/Pt catalysts with double-layer washcoat was better than the single washcoat catalyst.

A study on the oil transformer diagnostic technology using injection type UHF PD sensor (주입식 UHF PD 센서를 이용한 유입식 변압기 진단 기술 연구)

  • Kang, W.J.;Lee, C.J.;Kang, Y.S.;Park, J.B.;Lee, H.C.;Park, J.W.
    • Proceedings of the KIEE Conference
    • /
    • 2004.07c
    • /
    • pp.1891-1893
    • /
    • 2004
  • 이 논무에서는 유입식 변압를 대상으로 UHF 대역의 펄스신호를 검출하는 센서를 소개하고, 이를 이용한 방전 결함별 측정 결과를 소개한다. 측정결과는 기존의 PRPD법과 주파수 Domain과 위상 Domain에 대한 정보를 가지는 p-f-q 분석으로 측정 하였으며, 본 논문에서는 후자의 결과를 중심으로 서술 하였다.

  • PDF

Ginseng protopanaxatriol Saponins but not Protopanaxadiol Saponins Inhibit Spontaneous Motility of Intestine (인삼의 protopanaxatriol이 아니라 protopanaxatriol이 장관운동을 저해함)

  • Young-Hee Shin;Seo
    • Journal of Ginseng Research
    • /
    • v.21 no.1
    • /
    • pp.35-38
    • /
    • 1997
  • We investigated the effects of ginseng protopanaxadiol (PD) and protopanaxatriol (PT) saponins on the spontaneous contractility of intestine. Treatment with PD saponins showed a slight inhibition of spontaneous contraction of rabbit jejunum. In contrast, PT saponins showed much larger inhibition with dose-dependent manner in a range of 25~250 $\mu\textrm{g}$/ml. The inhibitory effect by PT saponins was not desensitized with continuous presence of PT saponins for several minutes. In addition, leu-enkephalin (1 PM) also inhibited the spontaneous contraction of rabbit jejunum but the in- hibition by leu-enkephalin was desensitized rapidly. The presence of PT saponins prevented the desenstization induced by leu-enkephalin. In conclusion, we found that PT saponins exert inhibition of spontaneous contractility of rabbit jejunum and the pattern of inhibition is different from that of opioid.

  • PDF

Fabrication of Pd/NiCr gate MISFET sensor for detecting hydrogen dissolved in Oil. (유중 용존수소 감지를 위한 Pd/NiCr 게이트 MISFET 센서의 제작)

  • Kim, Gop-Sick;Lee, Jae-Gon;Hahm, Sung-Ho;Choi, Sie-Young
    • Journal of Sensor Science and Technology
    • /
    • v.6 no.3
    • /
    • pp.221-227
    • /
    • 1997
  • The Pd/NiCr gate MISFET-type sensors were fabricated for detecting hydrogen dissolved in high-capacivity transformer oil. To improve stability and high concentration sensitivity of the sensor, Pd/NiCr double catalysis metal gate was used. To reduce the serious gate voltage drift of the sensor induced by hydrogen, the gate insulators of 2 FETs were constructed with double layer of silicon dioxide and silicon nitride. The hydrogen sensitivity of the Pd/NiCr gate MISFET is about a half of Pd/Pt gate MISFET's sensitivity but the Pd/NiCr gate MISFET has good stability and high concentration detectivity up to 1000 ppm.

  • PDF